Studies on mixed trialkyltin derivatives. VIII. Synthesis, characterization and biological activities of methyldicyclohexyltin aryloxyacetates was written by Jiang, Li;Yang, Zhi-Qiang;Xie, Qing-Lan;Shan, Shu-Xiang. And the article was included in Huaxue Xuebao in 1995.Formula: C9H10O4 This article mentions the following:
The synthesis of twenty XnC6H5-nOCH2CO2SnCy2Me (Cy = cyclohexyl; n = 1, X = H, 2-, 3-, and 4-Cl, 2- and 4-Br, 2-, 3-, and 4-Me, 2- and 4-MeO, 4-iodo, 3-NO2; n = 2, X2 = 2,3-, 2,4-, 2,6-, 3,4-, and 3,5-Me2, 2-MeO-4-allyl; n = 3, X3 = 2,4,5-Cl3) in 90-95% yields from bis(methyldicyclohexyltin) oxide and the corresponding aryloxyacetic acids is reported. Their characterization by IR and NMR (1H, 13C, 119Sn) spectroscopy is described. These compounds are five-coordinate, carboxylate-bridged polymers except 11 and 12. A good linear relation is found between the 119Sn chem. shifts and the aryl groups: δ119Sn = 6.23σ + 94.67, r = 0.943. The results of the preliminary bioassay showed that the compounds have better antibiotic activities to plant pathogenic fungi, herbicidal and inhibitory activities, especially high acaricidal activity. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Formula: C9H10O4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Formula: C9H10O4