Month: December 2022

Rudnitskaya, Olga V. published the artcileA balance of redox and ligand-exchange processes in the reaction of H₂[OsCl₆] with thiourea: Isolation and characterization of a novel osmium complex [(NH₂)₂CSSC(NH₂)₂]₂[Os^IVCl₆]Cl₂·3H₂O, Recommanded Product: Formamidine disulfide dihydrochloride, the publication is Inorganica Chimica Acta (2019), 352-356, database is CAplus.

A novel complex with the stoichiometry [(NH₂)₂CSSC(NH₂)₂]₂[Os^IVCl₆]Cl₂·3H₂O (1) was isolated as a product of the reaction of H₂[OsCl₆] with thiourea in concentrated HCl under deliberately optimized conditions favoring a partial thiourea oxidation to α,α’-dithiobisformamidinium dication but preserving hexachloroosmate [OsCl₆]²_– anions. A bromide analog [(NH₂)₂CSSC(NH₂)₂]₂[Os^IVBr₆]Br₂·3H₂O (2) is afforded by a similar reaction. A counter synthesis of 1 is accomplished via the direct ion-exchange reaction between H₂[OsCl₆] and [S₂C₂(NH₂)₄]Cl₂. Crystal structures of 1 and 2 are unambiguously established by synchrotron radiation-based single-crystal x-ray diffraction at 100 K. The two compounds are isostructural and are crystallized in the orthorhombic space group Cmcm, Z = 4. Unit cell parameters are for 1:a = 11.279(2) Å, b 13.611(3), c 16.731(3) Å; for 2: a 11.695(2), b 14.005(3), c 17.015(3) Å. The osmium atoms in [OsX₆]^2- (X = Cl or Br) anions adopt slightly distorted octahedral coordination. The α,α’-dithiobisformamidinium cations are paired into rings via the NH…Cl^– hydrogen bonds. The rings are further linked into a spatial network by H-bonds with water mols. and S…Cl nonvalence interactions.

Inorganica Chimica Acta published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Recommanded Product: Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Coniglio, Romina O. published the artcileEnzyme-assisted extraction of phenolic compounds and proteins from sugarcane bagasse using a low-cost cocktail from Auricularia fuscosuccinea, Related Products of ethers-buliding-blocks, the publication is International Journal of Food Science and Technology (2022), 57(2), 1114-1121, database is CAplus.

Sugarcane bagasse is the major byproduct of the sugarcane industry, and it can serve as a substrate for biotechnol. processes for obtaining value-added products. This study gave multiple adding values to sugarcane bagasse using it in two sep. bioprocesses. Sugarcane bagasse was used as a substrate for enzymic cocktail production from Auricularia fuscosuccinea LBM 244 and as a source of proteins and phenolic compounds A. fuscosuccinea LBM 244 enzyme cocktail-assisted extraction, com. enzyme assisted extraction and conventional extraction were compared. Enzymic-assisted extractions released 557-827% more protein content than those at 0 h. A. fuscosuccinea LBM 244 enzyme cocktail released 50% and 30% phenolic compounds more than conventional and com. enzyme extraction, resp. These phenolic compounds were represented mainly by ρ-coumaric and ferulic acids. On top of that, the cost of the enzymes in enzyme-assisted extraction was reduced fourfold using the A. fuscosuccinea LBM 244 enzyme cocktail.

International Journal of Food Science and Technology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Resta, Claudio published the artcileConsequences of Chirality on the Aggregation Behavior of Poly[2-methoxy-5-(2′-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV), Synthetic Route of 146370-51-6, the publication is Macromolecules (Washington, DC, United States) (2014), 47(15), 4847-4850, database is CAplus.

Poly[2-methoxy-5(2′-ethylhexoxy)-p-phenylenevinylene] (MEH-PPV) has been for the first time prepared and fully characterized in enantiopure (R) form. If the polymer mol. weight is sufficiently low, (R)-MEH-PPV assumes a helical supramol. structure in the solution aggregates, with consequences on the tendency to aggregation and on the fluorescence quenching, both of which are reduced with respect to the racemic analog.

Macromolecules (Washington, DC, United States) published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, Synthetic Route of 146370-51-6.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Rochette, Etienne published the artcileIsodesmic C-H Borylation: Perspectives and Proof of Concept of Transfer Borylation Catalysis, Formula: C11H17BO3S, the publication is Journal of the American Chemical Society (2019), 141(31), 12305-12311, database is CAplus and MEDLINE.

The potential advantages of using arylboronic esters as B source in the C-H borylation are discussed. The concept is showcased by using com. available 2-mercaptopyridine as a metal-free catalyst for the transfer borylation of heteroarenes, using arylboronates as borylation agents. The catalysis shows a unique functional group tolerance among C-H borylation reactions, tolerating notably terminal alkene and alkyne functional groups. The computational study of the mechanism is also described.

Journal of the American Chemical Society published new progress about 596819-12-4. 596819-12-4 belongs to ethers-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Ether,Boronate Esters,Boronic acid and ester, name is 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C11H17BO3S, Formula: C11H17BO3S.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lee, Yong Ho published the artcilePalladium-catalysed carboformylation of alkynes using acid chlorides as a dual carbon monoxide and carbon source, Product Details of C11H10O, the publication is Nature Chemistry (2021), 13(2), 123-130, database is CAplus and MEDLINE.

Hydroformylation, a reaction that installs both a C-H bond and an aldehyde group across an unsaturated substrate, is one of the most important catalytic reactions in both industry and academia. Given the synthetic importance of creating new C-C bonds, the development of carboformylation reactions, wherein a new C-C bond is formed instead of a C-H bond, would bear enormous synthetic potential to rapidly increase mol. complexity in the synthesis of valuable aldehydes. However, the demanding complexity inherent in a four-component reaction, utilizing an exogenous CO source, has made the development of a direct carboformylation reaction a formidable challenge. Here, we describe a palladium-catalyzed strategy that uses readily available aroyl chlorides as a carbon electrophile and CO source, in tandem with a sterically congested hydrosilane, to perform a stereoselective carboformylation of alkynes [e.g., 2-methylbenzoyl chloride + i-Pr₃SiH + n-PrCCPr-n â†?(Z)-I (up to 83%)]. An extension of this protocol to four chemodivergent carbonylations further highlights the creative opportunity offered by this strategy in carbonylation chem.

Nature Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Product Details of C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhao, Lanxiao published the artcileRegioselective C-H Alkylation of Aromatic Ethers with Alkenes by a Half-Sandwich Calcium Catalyst, SDS of cas: 93-04-9, the publication is ACS Catalysis (2022), 12(13), 7877-7885, database is CAplus.

The catalytic ortho-regioselective C-H alkylation of a of alkoxy-substituted benzene derivatives with alkenes could be achieved by the use of a half-sandwich calcium alkyl complex [(CpAr₅)Ca{CH(SiMe₃)₂}(THF)] (CpAr₅ = C₅Ar₅, Ar = 3,5-i-Pr-C₆H₃) as the precatalyst to form 1-alkoxy-2-phenethylbenzene derivatives I [R = H, 4-Me, 4-SMe, etc.; R¹ = OMe, OEt, i-Pr, etc.]. The potential catalytic reaction intermediates, half-sandwich calcium anisyl complexes [(CpAr₅)Ca(o-MeO-m-Ph-C₆H₃) (THF)₂] and [(CpAr₅)Ca(o-MeO-2-Np) (THF)₂] (Np = naphthyl), were isolated and X-ray structurally characterized. DFT calculations were carried out to elucidate the different reaction profiles of sp² and sp³ C-H activations.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C19H14Cl2, SDS of cas: 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Fu, Gui-Ming published the artcileAnalysis of microbial community, physiochemical indices, and volatile compounds of Chinese te-flavor baijiu daqu produced in different seasons, Safety of 1,2-Dimethoxybenzene, the publication is Journal of the Science of Food and Agriculture (2021), 101(15), 6525-6532, database is CAplus and MEDLINE.

Chinese te-flavor baijiu (CTF), the most famous Chinese baijiu in Jiangxi province, China, is made from a unique daqu. Its characteristic style is closely related to the daqu used for fermentation However, current studies on the effects of different production seasons on microbial communities, physicochem. indexes, and volatile compounds in CTF daqu are very rare. The relationships of microbial communities, physicochem. indexes, and volatile compounds in CTF daqu produced in summer (July and August) and autumn (Sept. and Oct.) were studied. The results of Illumina MiSeq sequencing indicated that there was greater bacterial diversity in the CTF daqu-7 (produced in July) and CTF daqu-8 (produced in August) and greater fungal diversity in the CTF daqu-9 (produced in Sept.) and CTF daqu-10 (produced in Oct.). The physicochem. indexes of CTF daqu produced in different seasons were significantly different. It was determined that CTF daqu-9 had the highest esterification and liquefaction abilities. A total of 44 volatile compounds, including alcs., esters, aldehydes, and ketones were identified in CTF daqu produced during different seasons. Among them, CTF daqu-9 had the greatest alc. content. Sept. (early autumn) is the best production period for CTF daqu. The results of the study provide a theor. basis for the standardized and uniform production of Chinese baijiu. 2021 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Kato, Kahoko published the artcilePrimary amine synthesis by hydrogen-involving reactions over heterogeneous cobalt catalysts, Computed Properties of 6850-57-3, the publication is Catalysis Science & Technology, database is CAplus.

A composite of metallic cobalt and silica particles that exhibits high catalytic performance for the selective synthesis of primary amines RNH₂ [R = heptyl, cyclohexyl, Bn, [5-(hydroxymethyl)oxolan-2-yl]methyl, etc.] via hydrogenation of nitriles RCN and reductive amination, even under mild conditions was reported. A mechanistic study revealed that the substrate nitrile and the product amine retarded the hydrogenation of secondary imine intermediates, which resulted in a selective reaction. On the basis of this knowledge, the selectivity for the primary amine was further improved by the addition of coordinating organic mols., which provided new insights into the control of selectivity toward primary amines unlike that with classical methods using ammonia.

Catalysis Science & Technology published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Computed Properties of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Perez, Dolores published the artcileEffect of non-wine Saccharomyces yeasts and bottle aging on the release and generation of aromas in semi-synthetic Tempranillo wines, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is International Journal of Food Microbiology (2022), 109554, database is CAplus and MEDLINE.

Interest in the use of non-conventional yeasts in wine fermentation has been increased in the last years in the wine sector. The main objective of this manuscript was to explore the aromatic diversity produced by wild and non-wine strains of S. cerevisiae, S. eubayanus, S. kudriavzevii, and S. uvarum species in young and bottle-aged Tempranillo wines as well as evaluate their fermentation capacity and the yield on ethanol, glycerol, and organic acids, that can contribute to diminishing the effects of climate change on wines. S. uvarum strain U1 showed the highest ability to release or de novo produce monoterpenes, such as geraniol and citronellol, whose values were 1.5 and 3.5-fold higher than those of the wine S. cerevisiae strain. We found that compared to the normal values for red wines, β-phenylethyl acetate was highly synthesized by U1 and E1 strains, achieving 1 mg/L. Addnl., after aging, wines of S. eubayanus strains contained the highest levels of this acetate. Malic acid was highly degraded by S. kudriavzevii yeasts, resulting in the highest yields of lactic acid (>5-fold) and Et lactate (>2.8-fold) in their wines. In aged wines, we observed that the modulating effects of yeast strain were very high in β-ionone. S. uvarum strains U1 and BMV58 produced an important aging attribute, Et isobutyrate, which was highly enhanced during the aging. Also, the agave S. cerevisiae strain develops an essential aroma after aging, reaching the highest Et leucate contents. According to the results obtained, the use of wild non-wine strains of S. cerevisiae and strains of the cryotolerant species S. eubayanus, S. kudriavzevii, and S. uvarum in Tempranillo wine fermentation increase the aroma complexity. In addition, wines from S. kudriavzevii strains had twice addnl. glycerol, those from S. uvarum 4-fold more succinic acid, while wines from wild strains yielded 1% volume/volume less ethanol which may solve wine problems associated with climate change.

International Journal of Food Microbiology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Pham, Johnny D. published the artcilePolymorphism of Oligomers of a Peptide from β-Amyloid, Safety of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, the publication is Journal of the American Chemical Society (2014), 136(14), 5432-5442, database is CAplus and MEDLINE.

This contribution reports solution-phase structural studies of oligomers of a family of peptides derived from the β-amyloid peptide (Aβ). We had previously reported the x-ray crystallog. structures of the oligomers and oligomer assemblies formed in the solid state by a macrocyclic β-sheet peptide containing the Aβ_15-23 nonapeptide. In the current study, we set out to determine its assembly in aqueous solution In the solid state, macrocyclic β-sheet peptide 1 assembles to form hydrogen-bonded dimers that further assemble in a sandwich-like fashion to form tetramers through hydrophobic interactions between the faces bearing V₁₈ and F₂₀. In aqueous solution, macrocyclic β-sheet peptide 1 and homolog 2a form hydrogen-bonded dimers that assemble to form tetramers through hydrophobic interactions between the faces bearing L₁₇, F₁₉, and A₂₁. In the solid state, the hydrogen-bonded dimers are antiparallel, and the β-strands are fully aligned, with residues 17-23 of one of the macrocycles aligned with residues 23-17 of the other. In solution, residues 17-23 of the hydrogen-bonded dimers are shifted out of alignment by two residues toward the C-termini. The two hydrogen-bonded dimers are nearly orthogonal in the solid state, while in solution the dimers are only slightly rotated. The differing morphol. of the solution-state and solid-state tetramers is significant, because it may provide a glimpse into some of the structural bases for polymorphism among Aβ oligomers in Alzheimer’s disease.

Journal of the American Chemical Society published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C25H23NO4, Safety of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem