Month: December 2022

Yang, Fa-Liu published the artcileAn Efficient Homogenized Ruthenium(II) Pincer Complex for N-Monoalkylation of Amines with Alcohols, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine, the publication is European Journal of Organic Chemistry (2017), 2017(24), 3481-3486, database is CAplus.

An ionic 2,6-bis(imidazo[1,2-α]pyridin-2-yl)pyridine-based N^N^N pincer ruthenium(II) complex exhibited high efficiency in the C-N bond formation between amines and alcs. by the “borrowing hydrogen” (BH) or “hydrogen autotransfer” (HA) concept. The synthetic protocol selectively generated monoalkylated amines without formation of tertiary amines during the reaction. The unique selectivity enabled the formation of sym. and asym. substituted diamines. This methodol. features several advantages including a low catalyst loading (as low as 0.5 mol-%), a short reaction time (as short as 2 h), and excellent N-monoalkylation selectivity.

European Journal of Organic Chemistry published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is Al2H32O28S3, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Zhen published the artcileCharacterization of the key odorants and their content variation in Niulanshan Baijiu with different storage years using flavor sensory omics analysis, Safety of 1,2-Dimethoxybenzene, the publication is Food Chemistry (2022), 131851, database is CAplus and MEDLINE.

Niulanshan Baijiu (NLS) is a light-flavor Baijiu (LFB) with a long history. The aroma-active compounds in six NLSs with different storage years were analyzed using gas chromatog.-olfactometry-mass spectrometry (GC-O-MS), coupled with Osme and aroma extraction dilution anal. (AEDA). A total of 59 odorants were identified, 5 odorants of them were, for the first time, identified as aroma-active compounds of LFB. After quantifying and calculating their odorant activity values (OAVs), 34 compounds had OAVs > 1, and the recombination and omission experiments further confirmed that Et acetate, Et acrylate, Et 2-methylbutyrate, γ-nonalactone, Et isovalerate, Et butyrate, isoamyl acetate, Et caprylate, Et valerate, 3-methylbutanal, β-damascenone, and geosmin have important contributions to the aroma of NLS. One-way ANOVA anal. further found that the contents of key odorants in NLS stored for four to five years were relatively stable. This study provides an important reference for product quality control in NLS.

Food Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C12H6NNaO4, Safety of 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gao, Anjiang published the artcileVolatile-char interactions during biomass pyrolysis: Reactor design toward product control, Name: 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Renewable Energy (2022), 1-7, database is CAplus.

This paper proposes a novel reactor featuring controllable adjustment of volatile-char interactions to investigate the pyrolysis of poplar wood and corresponding products. Controllable adjustment of volatile-char interactions enables the selective production of pyrolysis products. The oxygen content in biochar nearly disappears with the reduction of volatile-char interactions and the pore structure of biochar is improved after the interactions being intensified. Moreover, as the interactions reduce, the bio-oil yield increases by 1.23 times, and the outputs of acetic acid and phenols in the bio-oil exhibit decreasing trends, while that of levoglucosan is improved by nearly 4.5 times. Furthermore, the average mol. weight of bio-oil decreases from 786 to 322 g/mol with the continuous intensification of volatile-char interactions. It concludes that the controllable adjustment of volatile-char interactions plays a vital role in regulating the distribution of pyrolysis products and is of great importance to the production of light oil.

Renewable Energy published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Name: 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Yang published the artcileTrifluoromethyl Selenoxides: Electrophilic Reagents for C-H Trifluoromethylselenolation of (Hetero)Arene, Safety of 2-Methoxynaphthalene, the publication is Organic Letters (2022), 24(16), 3009-3013, database is CAplus and MEDLINE.

Herein, designed and synthesized the new electrophilic trifluoromethylselenolation reagents, trifluoromethyl selenoxides I [X = H, CF₃, CN], which were easy to prepare and easy-to-handle and were not moisture or air sensitive. The selenoxides are successfully applied to metal-free C-H trifluoromethylselenolation of a series of (hetero)arenes to gave ((trifluoromethyl)selanyl)aryl ArSeCF₃ [Ar = 4-HOC₆H₄, 1H-indol-3-yl, (5-methoxycarbonyl-1H-pyrrol-3-yl), etc.].

Organic Letters published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Safety of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

He, Xinxin published the artcileBis-selenonium Cations as Bidentate Chalcogen Bond Donors in Catalysis, Safety of 2-Methoxynaphthalene, the publication is ACS Catalysis (2021), 11(20), 12632-12642, database is CAplus.

Hydrolytically stable bidentate Lewis acid catalysts derived from selenonium dicationic centers were developed. The bis-selenonium catalysts were employed in the activation of imine and carbonyl groups in various transformations with good yields and selectivity. Lewis acidity of the bis-selenonium salts was found to be stronger than that of the monoselenonium systems, attributed to the synergistic effect of the two cationic selenonium centers. In addition, the bis-selenonium catalysts were not inhibited by strong bases or moisture.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Safety of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sokolsky, Alexander published the artcileSpirastrellolide E: synthesis of an advanced C(1)-C(24) southern hemisphere, Product Details of C21H37BO, the publication is Tetrahedron Letters (2015), 56(23), 3160-3164, database is CAplus and MEDLINE.

The synthesis of a C(1)-C(24) advanced southern hemisphere fragment (I) towards the total synthesis of spirastrellolide E has been achieved. Highlights of the route include a highly convergent Type I Anion Relay Chem. (ARC) tactic for fragment assembly, in conjunction with a directed, regioselective gold-catalyzed alkyne functionalization to generate the central unsaturated [6,6]-spiroketal.

Tetrahedron Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C9H9F5Si, Product Details of C21H37BO.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Xu, Yanlin published the artcileThe role of Nb₂O₅ in controlling metal-acid sites of CoMoS/γ-Al₂O₃ catalyst for the enhanced hydrodeoxygenation of guaiacol into hydrocarbons, COA of Formula: C8H10O2, the publication is Journal of Catalysis (2022), 19-28, database is CAplus.

Transformation of lignin-derived feedstocks into valuable hydrocarbons is of significant importance but still challenging. Herein, we report a novel and highly efficient bifunctional metal/acid CoMoS/γ-Al₂O₃ catalyst with doping of Nb₂O₅ for the hydrodeoxygenation of guaiacol. The dopant Nb₂O₅ significantly improves the HDO activity of CoMoS/γ-Al₂O₃ catalyst from 72.4% to 97.5% at 340°C. Extensive characterizations confirm that the modification of Nb₂O₅ weakens the metal-support interaction, and thus improves the sulfidation degree of Mo species and the dispersion of MoS₂ phases, leading to more MoS₂ edges. Accordingly, the induced formation of more Bronsted acid sites originating from -SH on increased MoS₂ edges greatly promotes the C_(sp2)-O scissions of phenolics, and therefore enhances the yield of hydrocarbons especially benzene. This work focuses on the mechanistic insights into the effect of Nb₂O₅ on sulfided Mo-based catalyst in the HDO of lignin compound and provides a promising approach for facilitation of lignin valorization with extensive applications.

Journal of Catalysis published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C5H6N2O2, COA of Formula: C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Hongliang published the artcileElectrophilic amidomethylation of arenes with DMSO/MeCN reagents, Related Products of ethers-buliding-blocks, the publication is Organic Chemistry Frontiers (2022), 9(9), 2430-2437, database is CAplus.

An efficient electrophilic amidomethylation of aromatics was described to construct N-benzylic amides, which are core structures in drugs and natural products. The simple combination of DMSO (DMSO, as the CH₂ unit) and acetonitrile (MeCN, as the nitrogen unit) as a highly active amidomethylation reagent enables the efficient C-C, C-N and C=O bond construction. Notably, this method provides a practical protocol for the efficient preparation of deuterated benzylamine derivatives with easily available d₆-DMSO or d₃-MeCN, and is also applied in the concise synthesis of Nonivamide and Pimavanserin.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C15H24S, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Xu, Ren-Rui published the artcilePalladium-catalyzed cascade Heck-type thiocarbonylation for the synthesis of functionalized thioesters, Safety of 2-Methoxynaphthalene, the publication is Organic Chemistry Frontiers (2022), 9(5), 1417-1421, database is CAplus.

A palladium-catalyzed cascade Heck-type cyclization and carbonylation reaction has been developed for the synthesis of functionalized thioesters. With arylsulfonyl chlorides as odorless and readily available sulfur sources, a variety of thioesters were obtained in moderate to good yields with good functional group compatibility. In this system, Mo(CO)₆ acts as both a convenient CO surrogate and a suitable reductant.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C8H8O3, Safety of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Yonglong published the artcileTunable Photocatalytic Two-Electron Shuttle between Paired Redox Sites on Halide Perovskite Nanocrystals, Recommanded Product: 2-Methoxynaphthalene, the publication is ACS Catalysis (2022), 12(10), 5903-5910, database is CAplus.

Perovskite semiconductors as advanced solar energy-converting materials are promising catalysts for photoredox organic synthesis. Despite the high concentration of charge carriers generated on the perovskite surface, efficient utilization of these nonequilibrium and shambolic energetic carriers to trigger a chem. reaction remains a hot and challenging subject. Here, we report a photon-mediated electron shuttle between paired redox sites on perovskite nanocrystals for the reformation of highly stable carbon-halogen bonds, where both surface electrons and holes are utilized simultaneously. The photo-redox cascade can be effortlessly tailored by precise control of the surface-reducing/-oxidizing reaction rates, which unlocks the transformation for a wide range of (het)arenes. This work demonstrates colloidal perovskite photocatalysts for the direct installation of more than 10 different synthetically important functional groups onto arenes and heteroarenes.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem