Month: December 2022

Luo, Huihui published the artcileNitrogen-Doped Carbon-Modified Cobalt-Nanoparticle-Catalyzed Oxidative Cleavage of Lignin β-O-4 Model Compounds under Mild Conditions, SDS of cas: 183303-74-4, the publication is ACS Sustainable Chemistry & Engineering (2018), 6(11), 14188-14196, database is CAplus.

A noble-metal-free Co-based catalyst, derived from pyrolysis of natural vitamin B₁₂ on activated carbon, is developed for the first time for one-pot oxidative cleavage of lignin linkages to phenols and aromatic esters with mol. oxygen as the oxidant under mild reaction conditions. High yields of phenol were obtained, and no oxidative coupling of phenol was produced based on the present cobalt catalyst. Compared to the previous report, the present catalyst can achieve the oxidative cleavage of β-O-4 ketones even at room temperature using a dioxygen balloon. The heterogeneous catalyst shows robust recyclability and can be conveniently recovered and reused up to eight times without an appreciable loss of catalytic activity. Moreover, this catalyst system can realize the bond cleavage of organosolv lignin. The evidence of depolymerization was given by two-dimensional heteronuclear single quantum coherence NMR and gel permeation chromatog. Characterization of the catalyst by inductively coupled plasma, N₂ adsorption-desorption, Raman spectroscopy, SEM, transmission electron microscopy (TEM), high-resolution TEM, high-angle angular dark-field scanning TEM, energy-dispersive X-ray spectroscopy, XPS, and control experiments provide a fundamental understanding of the catalytic materials and the reaction pathway. Co₃O₄ in situ supported on a N-doped carbon matrix by the way of high-temperature pyrolysis might be a catalytically active species. Two reaction intermediates are detected and confirmed by gas chromatograph-mass spectrometry.

ACS Sustainable Chemistry & Engineering published new progress about 183303-74-4. 183303-74-4 belongs to ethers-buliding-blocks, auxiliary class Benzene,Alcohol,Ether, name is 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol, and the molecular formula is C16H18O4, SDS of cas: 183303-74-4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Shu, Bin published the artcileNewly generated and increased bound phenolic in lychee pulp during heat-pump drying detected by UPLC – ESI-triple-TOF-MS / MS, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Journal of the Science of Food and Agriculture (2022), 102(4), 1381-1390, database is CAplus and MEDLINE.

During the thermal processing of fruit, it has been observed for phenolic compounds to either degrade, polymerize, or transfer into macromols. In this study, the bound and free phenolic compound composition, content, and phenolic-related enzyme activity of lychee pulp were investigated to determine whether the free phenolic had converted to bound phenolic during heat-pump drying (HPD). It was found that after HPD, when compared with the fresh lychee pulp (control), the content of bound phenolics of dried lychee pulp had increased by 62.69%, whereas the content of free phenolics of dried lychee pulp decreased by 22.26%. It was also found that the antioxidant activity of bound phenolics had also increased after drying. With the use of high-performance liquid chromatog.-tandem mass spectrometry, it was identified that (+)-gallocatechin, protocatechuic aldehyde, isorhamnetin-3-O-rutoside, 3,4-dihydroxybenzeneacetic acid, and 4-hydroxybenzoic acid were newly generated during HPD, when compared with the control sample. After drying, the contents of gallic acid, catechin, 4-hydroxybenzoic acid, vanillin, syringic acid, and quercetin in bound phenolics had also increased, and polyphenol oxidase and peroxidase still showed enzyme activity, which could be related to the conversion of free phenolics to bound phenolics. Overall, during the thermal processing of lychee pulp, the free phenolics weres found to be converted into bound phenolics, new substances were generated, and antioxidant activity was increased. Hence, it was concluded that HPD improved the bound phenolics content of lychee pulp, thus providing theor. support for the lychee processing industry. 2021 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C17H27BN2O4S, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Luo, Zhiqiang published the artcileA Stable Zn-Based Metal-Organic Framework as an Efficient Catalyst for Carbon Dioxide Cycloaddition and Alcoholysis at Mild Conditions, Formula: C4H10O2, the publication is Catalysis Letters (2020), 150(5), 1408-1417, database is CAplus.

Developing highly efficient heterogeneous catalysts for cycloaddition of CO₂ and epoxides to produce cyclic carbonates is promising but challenging. In this work, a novel three-dimensional metal organic framework (MOF) with cylinder pore systems and unsaturated Zn sites has been demonstrated as potent candidate in CO₂ fixation at mild and solvent-free conditions. The Zn(atz)(bdc)_0.5, where atz = aminotriazole and H₂bdc = terephthalic, exhibits microporous nature that can regulate the catalytic interaction of active centers and substrates. The structure stability has been systematically investigated and proven to be sufficient for practical application. Furthermore, the cooperative effects of porosity, CO₂ binding affinity, activation centers, and synergism with co-catalyst have been deeply investigated. Moreover, high propylene epoxide conversion (97%) and selectivity (> 99%) have been achieved at mild conditions (60°C and 1 MPa) with excellent cycle stability. Owing to the well-defined pore system, an obvious substrates selectivity has been clearly observed A possible catalytic mechanism has been proposed and verified by DFT calculations Furthermore, the prepared Zn-MOF can also be used as an efficient heterogeneous catalyst for the reaction of epoxides with alcs. to produce β-alkoxy alc.

Catalysis Letters published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lu, Ye published the artcileHydrogenation of nitriles to primary amines catalyzed by an unsupported nanoporous palladium catalyst: understanding the essential reason for the high activity and selectivity of the catalyst, Recommanded Product: (2-Methoxyphenyl)methanamine, the publication is Nanoscale (2022), 14(26), 9341-9348, database is CAplus and MEDLINE.

An efficient and highly selective heterogeneous catalyst system for nitrile hydrogenation was developed using unsupported palladium nanopores (PdNPore). The PdNPore-catalyzed selective hydrogenation of nitriles proceeded smoothly, without any additives, under mild conditions (low H₂ pressure and low temperature) to yield primary amines with satisfactory to excellent yields. Systematic studies demonstrated that the high activity and excellent selectivity of the PdNPore originated from its good Lewis acidity and porous structure. No palladium leached from the PdNPore during the hydrogenation reaction. Moreover, the catalyst was easily recovered and reused without any loss of catalytic activity. A deuterium-hydrogen exchange reaction clearly indicated that the present hydrogenation involves heterolytic H₂ splitting on the surface of the PdNPore catalyst.

Nanoscale published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Recommanded Product: (2-Methoxyphenyl)methanamine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Liang, Ge published the artcileDirect C-H Thiolation for Selective Cross-Coupling of Arenes with Thiophenols via Aerobic Visible-Light Catalysis, SDS of cas: 93-04-9, the publication is Organic Letters (2021), 23(20), 8082-8087, database is CAplus and MEDLINE.

An aerobic metal-free, visible-light-induced regioselective thiolation of phenols with thiophenols is reported. The cross-coupling protocol exhibits great functional group tolerance and high regioselectivity. Mechanistic studies revealed that the disulfide radical cation plays a crucial role in the visible-light catalysis of aerobic thiolation. Simply controlling the equivalent ratio of substrates enables the selective formation of sulfide or sulfoxide products with high activity in a one-pot reaction.

Organic Letters published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, SDS of cas: 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

An, Shengxin published the artcileEfficient lignin depolymerization with Ru- and W-modified bi-functional solid acid catalyst, Safety of 1,2-Dimethoxybenzene, the publication is BioResources (2022), 17(1), 1062-1089, database is CAplus.

A novel Ru-modified composite catalyst, Ru-W/Sn-AlOx, was prepared, and the effects of the catalyst on lignin depolymerization were investigated in this study. The catalyst converted approx. 95% lignin into liquid product at 300°C in 12 h and 2/3 of the liquid product could be soluble in petroleum ether. The petroleum ether (PE) soluble product was mainly composed of monomers, dimers and some trimmers. This indeed indicated that the catalyst could effectively depolymerize lignin into small-mol. products. 7.22% of monomers was obtained at 310°C for 12 h. Meanwhile, the catalyst effectively reduced the char formation to 2%. After the catalytic depolymerization, the higher heating value (HHV) of the liquid product increased from 25.7 to 32.4 MJ/kg. The product could be utilized as fuel additive or converted to biofuels. This catalysis system showed great potential in the conversion of lignin into biofuels.

BioResources published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Huixia published the artcileDiscovery, SAR, and putative mode of action of N-benzyl-2-methoxybenzamides as potential bleaching herbicides, Application In Synthesis of 6850-57-3, the publication is Pest Management Science (2021), 77(6), 2804-2811, database is CAplus and MEDLINE.

Herbicides acting on biosynthesis of plant pigments have contributed greatly to weed control in recent years. In our previous studies, 2-methoxybenzamides were discovered as a novel type of lead compound for the development of bleaching herbicides. A total of 67 benzamide analogs were synthesized and evaluated for herbicidal activity. The structure-activity relationship (SAR) revealed that a methoxyl substitution at the 2-position of the benzoyl moiety is essential for the herbicidal activity of benzamide derivatives, and introduction of small substituents at the meta- or para-position of the benzylamine moiety is also beneficial. Compounds 4, 43 and 44 showed 100% inhibition against Abutilon theophrasti and Amaranthus retroflexus at an application rate of 150 g a.i. ha^-1. The relationship between the structure and herbicidal activity of 2-methoxybenzamides was discussed intensively. Compounds 4, 43 and 44 may serve as novel candidates with a bleaching effect.

Pest Management Science published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C4H12ClNO, Application In Synthesis of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gao, Hailian published the artcileEnhanced oxidative depolymerization of lignin in cooperative imidazolium-based ionic liquid binary mixtures, Recommanded Product: 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Bioresource Technology (2022), 127333, database is CAplus and MEDLINE.

The aerobic oxidation of lignin model 2-phenoxyacetophenone (2-PAP) in cooperative ionic liquid mixtures (CoILs) with 1-ethyl-3-methylimidazolium acetate ([C₂C₁i.m.]OAc) and 1-benzyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([B_ZC₁i.m.]NTf₂) was investigated. Complete degradation of 2-PAP was achieved with [C₂C₁i.m.]OAc/[B_ZC₁i.m.]NTf₂ molar ratio (R_IL) of 1/1 and 1/2 at 100 °C for 2 h. The conversion and product yields from CoILs were higher than those in pure ILs, indicating the cooperative effects of [C₂C₁i.m.]OAc/[B_ZC₁i.m.]NTf₂ on cleaving aryl-ether bonds. [C₂C₁i.m.]OAc promoted the catalytic cleavage of aryl-ether bonds and solvation, and [B_ZC₁i.m.]NTf₂ induced the formation of alkyl radicals and enhanced the product selectivity. Accordingly, the highest conversion of alkali lignin (79.8%) was obtained with RIL of 5/1 at 100 °C for 2 h, and phenol monomers (306 mg/g) were selectively produced. The CoILs exhibited good catalytic capacities for oxidative depolymerization of lignin, which strongly depends on the changes in intermol. interactions and structural organization with varying RIL.

Bioresource Technology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Recommanded Product: 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Yan published the artcileComparison analysis of widely-targeted metabolomics revealed the variation of potential astringent ingredients and their dynamic accumulation in the seed coats of both Carya cathayensis and Carya illinoinensis, Category: ethers-buliding-blocks, the publication is Food Chemistry (2022), 131688, database is CAplus and MEDLINE.

Pecan and hickory nuts are two of consumers favorite ones. Pecan seeds can be eaten fresh, while hickory ones must remove astringency before eating. Here, we reported that total phenols, flavonoids and condensed tannins of hickory seeds were reduced after de-astringent treatments. They gradually increased with development, showing higher levels in hickory seed coat at mid-late periods than that in pecans. Widely-targeted metabonomics anal. of developing testa identified 424 kinds of components, including 101, 38, 58, 27 classes of flavonoids, tannins, phenolic acids, organic acids and others, showing 16 different changing trends. Notably, most kinds of flavonoids, hydrolysable tannins and phenolic acids at maturity were more than that of pecans, while oligomeric condensed tannins were opposite. Gene expression anal. provided further explanations for their dynamic accumulation. These results unraveled potential astringent components in hickory testa and preliminary mol. mechanisms of their dynamic changes, offering theor. basis for the targeted de-astringency.

Food Chemistry published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Cui, Wenjing published the artcileBase-Free Oxidative Coupling of Amines and Aliphatic Alcohols to Imines over Au-Pd/ZrO₂ Catalyst under Mild Conditions, HPLC of Formula: 6850-57-3, the publication is Russian Journal of Physical Chemistry A (2021), 95(5), 958-967, database is CAplus.

The base-free synthesis of imines from amines and aliphatic alcs. over Au-Pd alloy catalysts under ambient conditions were developed. A series of Au-Pd/ZrO₂ bimetallic catalysts with varying metal loadings and Au : Pd molar ratios were prepared and their catalytic performance were investigated. The 3.0 wt % Au-Pd/ZrO₂ alloy catalyst with Au : Pd molar ratio of 1 : 1 showed the best catalytic performance. Under air atm., various imines were obtained from coupling of amines and aliphatic alcs. without any additives or promoters. The performance of alloy NPs were superior to that of monometallic catalysts due to the synergistic effect which were demonstrated by TEM, XPS, and UV-Vis characterization. Transformation differed slightly from those reactions between amine and benzyl alc. and a possible mechanism were proposed. Moreover, the Au-Pd/ZrO₂ catalyst was easily separated and reused for at least five successive runs with high catalytic activity.

Russian Journal of Physical Chemistry A published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, HPLC of Formula: 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem