Author: Jessica.F

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Related Products of 73724-45-5.

Mukherjee, Nabanita;Roy, Rajsekhar;Ghosh, Satyajit;Ghosh, Surajit research published 《 Self-Assembled Antimitotic Peptide Vesicle Designed from α,β-Tubulin Heterodimer Interface for Anticancer Drug Delivery》, the research content is summarized as follows. Peptide based anticancer mol. act simultaneously as potent anticancer therapeutic as well as unique drug delivery vehicle for the targeted delivery of often cytotoxic abysmally bioavailable anticancer drugs to their designated organelle. The atypical self-assembling propensity of peptides gives rise to distinct nanostructures capable of encapsulating various drug payload. Among three different types of cytoskeletons presents in eukaryotes, microtubule plays a quintessential role during the course of cell cycle. Microtubule-targeting agents continues to be the most unwavering classes of antineoplastic drugs for the treatment of cancer. Any intervention to the dynamic tubulin assembly-disassembly process will definitely lead to complete perturbation of total cell division process. Several tubulin targeted antimitotic drugs had been designed as well as discovered to disrupt this dynamic nature of tubulin monomers either by inducing extensive polymerization or depolymerization, thereby facilitating overall cell cycle arrest. However, in cancer cells, aberrant mTOR activity causes growing resistance against numerous tubulin targeted drugs inducing metastasization, and simultaneous invasion to new healthy tissues. In recent years, numerous tubulin targeted drugs have been found to have high activity in a combination with mTOR inhibitors like tacrolimus, everolimus (RAD001), etc. but restrained bioavailability, non-specificity and quick excretion are the major impediments for the successful implementation. Combining the immense importance of protein-peptide interaction for the development of future anticancer therapeutics as well as self-assembling propensity of peptides we have taken a unique approach to craft a microtubule targeting antimitotic peptide designed from α,β-tubulin heterodimer interface, which promotes both in vitro and in vivo tubulin depolymerization, exhibiting middling toxicity towards MCF7 cells, causing cell cycle arrest. Further AFM images of this β-sheet forming peptide reveals that this peptide upon self-assembly give rise to spectacular vesicle structural characteristics which can be used as a vehicle for a combination delivery of Docetaxel and RAD001 in order to enhance their individual therapeutic potency. Encapsulation of propidium iodide and concomitant release studies suggest that Pep-4 vesicles could be a potential candidate for tubulin targeted sustained release of therapeutics. Here, our designed peptide vesicles are found to capable for the delivery of tubulin targeting drug Docetaxel along with an well-known mTOR inhibiting drug RAD001 successfully to breast cancer cell line in order to achieve a robust symbiotic effect.

73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Related Products of 73724-45-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Application In Synthesis of 122775-35-3.

Mudasani, Gopal;Paidikondala, Kalyani;Gurska, Sona;Maddirala, Shambabu Joseph;Dzubak, Petr;Das, Viswanath;Gundla, Rambabu research published 《 C-5 Aryl Substituted Azaspirooxindolinones Derivatives: Synthesis and Biological Evaluation as Potential Inhibitors of Tec Family Kinases》, the research content is summarized as follows. In this review, a structure-activity relationship study of a new series of 5′-(benzo[d][1,3]dioxol-5-yl)spiro[piperidine-4,3′-pyrrolo[2,3-b]pyridin]-2′(1’H)-one linked with N-acyl and C-5 aryl-substituted scaffolds I [R = 3,4-difluorophenyl, 3,4,5-trimethoxyphenyl, benzodioxol-5-yl, etc.; R¹ = H, (1-fluorocyclopropyl)carbonyl, 2-fluoro-2-methylpropanyl, biotinyl, [1-(methoxycarbonyl)cyclopropyl]carbonyl, etc.] in a panel of interleukin-2-inducible kinase (ITK) and Bruton tyrosine kinase (BTK) cancer cell lines was conducted. Four compounds I [R = benzodioxol-5-yl; R¹ = (1-fluorocyclopropyl)carbonyl, 2-fluoro-2-methylpropanyl, biotinyl, [1-(methoxycarbonyl)cyclopropyl]carbonyl] showed high antiproliferative activity against ITK and BTK cell lines. Compounds I [R = benzodioxol-5-yl; R¹ = (1-fluorocyclopropyl)carbonyl, 2-fluoro-2-methylpropanyl] with a C-5 benzodioxole group and gem-dialkyl group attached to carbonyl on piperidine were highly effective in ITK-high Jurkat and CEM cell lines, and compound I [R = benzodioxol-5-yl; R¹ = biotinyl], a biotin analog, was identified as a good inhibitor of BTK-high RAMOS cells. Compound I [R = benzodioxol-5-yl; R¹ = [1-(methoxycarbonyl)cyclopropyl]carbonyl] with cyclopropyl group attached to carbonyl on piperidine also showed good activity in ITK and BTK cell lines.

Application In Synthesis of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Synthetic Route of 122775-35-3.

Mori-Quiroz, Luis M.;Comadoll, Chelsea G.;Super, Jonathan E.;Clift, Michael D. research published 《 Exploiting Iminoquinones as Electrophilic at Nitrogen “N+” Synthons for C-N Bond Construction》, the research content is summarized as follows. New methods for C-N bond construction exploiting the N-centered electrophilic character of iminoquinones were reported. Iminoquinones, generated in situ via the condensation of o-vinylanilines with benzoquinones, underwent acid-catalyzed cyclization to afford N-arylindoles I [R = H, F; R¹ = H, Me, Ph, etc.; R² = H, Me; R³ = H, Cl, CO₂Me, etc.; Ar = 3,5-di-(t-Bu)-4-OHC₆H₂, 3,5-di-Me-4-OHC₆H₂, 3,5-di-(t-Bu)-2-OHC₆H₂, 10-hydroxy-9-phenanthryl] in excellent yields. Under similar reaction conditions, homoallylic amines reacted analogously to afford N-arylpyrroles II [R⁴ = Ph, 3-MeOC₆H₄, 4-FC₆H₄, 2,6-di-FC₆H₃, 2,3-dihydrobenzofuran-5-yl; R⁵ = H, 4-MeC₆H₄; Ar = 3,5-di-(t-Bu)-4-OHC₆H₂]. Addnl., organometallic nucleophiles were shown to add to the nitrogen atom of N-alkyliminoquinones to provide amine products. Finally, iminoquinones were shown to be competent electrophiles for copper-catalyzed hydroamination.

122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Synthetic Route of 122775-35-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Related Products of 111-90-0.

Montano, Alfredo;Cortes-Delgado, Amparo;Sanchez, Antonio Higinio;Ruiz-Barba, Jose Luis research published 《 Production of volatile compounds by wild-type yeasts in a natural olive-derived culture medium》, the research content is summarized as follows. The production of volatile compounds in naturally fermented green table olives from Manzanilla cultivar was investigated. A total of 62 volatile compounds were detected after 24 wk of fermentation To clarify the contribution of yeasts to the formation of these compounds, such microorganisms were isolated from the corresponding fermenting brines. Five major yeast strains were identified: Nakazawaea molendinolei NC168.1, Zygotorulaspora mrakii NC168.2, Pichia manshurica NC168.3, Candida adriatica NC168.4, and Candida boidinii NC168.5. When these yeasts were grown as pure cultures in an olive-derived culture medium, for 7 days at 25°C, the number of volatiles produced ranged from 22 (P. manshurica NC168.3) to 60 (C. adriatica NC168.4). Contribution of each yeast strain to the qual. volatile profile of fermenting brines ranged from 19% (P. manshurica NC168.3) to 48% (Z. mrakii NC168.2 and C. adriatica NC168.4). It was concluded that C. adriatica NC168.4 presented the best aromatic profile, being a solid candidate to be part of a novel starter culture to enhance the organoleptic properties of naturally fermented green table olives.

Related Products of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. HPLC of Formula: 111-90-0.

Mohammadian, Esmaeil;Foroumadi, Alireza;Hasanvand, Zaman;Rahimpour, Elaheh;Zhao, Hongkun;Jouyban, Abolghasem research published 《 Simulation of mesalazine solubility in the binary solvents at various temperatures》, the research content is summarized as follows. The present study aims are to develop general models based on Abraham solvation parameters and Hansen solubility parameters to predict mesalazine solubility in cosolvency systems at different temperatures The Jouyban-Acree model as an accurate math. model is combined with physicochem. parameters of the Abraham solvation parameters and the Hansen solubility parameters to achieve the predictive cosolvency models. KAT-LSER model was also applied for the representation of mesalazine solubility data at 298.2 K. The applicability of the proposed methods was evaluated by calculating the overall mean relative deviations (MRDs %) values of the solubility data for mesalazine in 11 cosolvency systems and discussed. The trained models present a good estimation of the solubility behavior of mesalazine in various cosolvency systems, including aqueous and non-aqueous mixtures The essential information presented by these models can be used in different stages of new drug and drug candidate discovery, development, and industrial procedures, so that they permit the scientist the choice the best solvent system for mesalazine with considering the fact that some solvents such as ethanol, propylene glycol, polyethylene glycols, N-Me pyrrolidone, and carbitol are commonly used solvents in drug preparation procedure and other organic and volatile solvents are used in the extraction and purification step.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., HPLC of Formula: 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Recommanded Product: 2-Methoxy-N-methylethanamine.

Mohamad, Rapidah;Awang, Normah;FarahanaKamaludin, Nurul research published 《 Synthesis and characterization of new organotin (IV)(2-Methoxyethyl)- methyldithiocarbamate complexes》, the research content is summarized as follows. Three new organotin(IV) dithiocarbamate complexes (complexes 1-3) employing (2-methoxyethyl)-methylamine as their secondary amine were successfully synthesized in situ. Elemental anal. of the complexes gave the general formula of RnSn[S2CN(C2H4OCH3)(CH3)]n-2 where R = C4H9(Bu) and C6H5Phfor n = 2; R = C6H11 (Cy) for n = 3. The complexes were analyzed using FTIR and 1H, 13C, and 119Sn NMR. The important absorption peaks and chem. shift of NCS2 carbon were found in all the three complexes. 119Sn NMR suggested that tin atom in the complexes are coordinated by five and six coordination numbers

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Recommanded Product: 2-Methoxy-N-methylethanamine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. COA of Formula: C4H11NO.

Mohamad, Rapidah;Awang, Normah;Kamaludin, Nurul Farahana;Pim, Norraphat Uttraphan research published 《 Spectral characterization and X-Ray crystallographic studies of some triphenyltin(IV) dithiocarbamates compounds》, the research content is summarized as follows. Three novel triphenyltin(IV) compounds with N-(2-methoxyethyl)-N-methyldithiocarbamate (1), N-benzyl-N-phenethyldithiocarbamate (2) and N-methyl-N-hexyldithiocarbamate (3) ligands have been successfully synthesized via in situ insertion method. The newly synthesized compounds gave fairly sharp m.ps. indicating their purity and were successfully isolated as crystalline solids. All the compounds have been characterized by CHNS elemental anal., FT-IR, ¹H, ¹³C and ¹¹⁹Sn NMR spectroscopies. A single C-S vibration band around 1000cm^-1 was observed in all compounds, suggesting bidentate bonding of dithiocarbamate ligand to tin metal through both sulfur donor atoms. The crystal structures of all the compounds were determined by x-ray crystallog. All the compounds were crystallized in triclinic system. The single crystal x-ray diffraction data illustrated all three dithiocarbamato ligands are bidentate but in asym. fashion due to D (Sn-S) bond length and the geometry at the tin center is described as distorted trigonal bipyramidal.

COA of Formula: C4H11NO, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers do have nonbonding electron pairs on their oxygen atoms, 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Application In Synthesis of 38256-93-8.

Mohamad, Rapidah;Awang, Normah;Kamaludin, Nurul Farahana;Jotani, Mukesh M.;Tiekink, Edward R. T. research published 《 Crystal structures and Hirshfeld surface analyses of bis[N,N-bis(2-methoxyethyl)dithiocarbamato-κ²S,S’]di-n-butyltin(IV) and [N-(2-methoxyethyl)-N-methyldithiocarbamato-κ²S,S’]triphenyltin(IV)》, the research content is summarized as follows. The crystal and mol. structures of the two title organotin dithiocarbamate compounds, [Sn(C₄H₉)₂(C₇H₁₄NO₂S₂)₂], (I), and [Sn(C₆H₅)₃(C₅H₁₀NOS₂)], (II), are described. Both structures feature asym. bound dithiocarbamate ligands leading to a skew-trapezoidal bipyramidal geometry for the metal atom in (I) and a distorted tetrahedral geometry in (II). The complete mol. of (I) is generated by a crystallog. twofold axis (Sn site symmetry 2). In the crystal of (I), mols. self-assemble into a supramol. array parallel to (10-1) via methylene-C-H···O(methoxy) interactions. In the crystal of (II), supramol. dimers are formed via pairs of weak phenyl-C-H···π(phenyl) contacts. In each of (I) and (II), the specified assemblies connect into a three-dimensional architecture without directional interactions between them. Hirshfeld surface analyses confirm the importance of H···H contacts in the mol. packing of each of (I) and (II), and in the case of (I), highlight the importance of short methoxy-H···H(butyl) contacts between layers.

Application In Synthesis of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Safety of 2-Methoxy-N-methylethanamine.

Mohamad, Rapidah;Awang, Normah;Kamaludin, Nurul F.;Jotani, Mukesh M.;Tiekink, Edward R. T. research published 《 Di-n-butylbis[N-(2-methoxyethyl)-N-methyldithiocarbamato-κ²S,S′]tin(IV): crystal structure and Hirshfeld surface analysis》, the research content is summarized as follows. The complete mol. of the title compound, [Sn(C₄H₉)₂(C₅H₁₀NOS₂)₂], is generated by a crystallog. mirror plane, with the Sn^IV atom and the two inner methylene C atoms of the Bu ligands lying on the mirror plane; statistical disorder is noted in the two terminal Et groups, which deviate from mirror symmetry. The dithiocarbamate ligand coordinates to the metal atom in an asym. mode with the resulting C₂S₄ donor set defining a skew trapezoidal bipyramidal geometry; the Bu groups are disposed to lie over the longer Sn-S bonds. Supramol. chains aligned along the a-axis direction and sustained by methylene-C-H···S(weakly coordinating) interactions feature in the mol. packing. A Hirshfeld surface anal. reveals the dominance of H···H contacts in the crystal.

Safety of 2-Methoxy-N-methylethanamine, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Name: 2-Methoxy-N-methylethanamine.

Mohamad, Rapidah;Awang, Normah;Jotani, Mukesh M.;Tiekink, Edward R. T. research published 《 Distinct coordination geometries in bis[N,N-bis(2-methoxyethyl)dithiocarbamato-κ²S,S′]diphenyltin(IV) and bis[N-(2-methoxyethyl)-N-methyldithiocarbamato-κ²S,S′]diphenyltin(IV): crystal structures and Hirshfeld surface analysis》, the research content is summarized as follows. The crystal and mol. structures of two diphenyltin bis(dithiocarbamate)s, [Sn(C₆H₅)₂(C₅H₁₀NOS₂)₂], (I), and [Sn(C₆H₅)₂(C₇H₁₄NO₂S₂)₂], (II), are described. In (I), in which the metal atom lies on a twofold rotation axis, the dithiocarbamate ligand coordinates with approx. equal Sn-S bond lengths and the ipso-C atoms of the Sn-bound Ph groups occupy cis-positions in the resulting octahedral C₂S₄ donor set. A quite distinct coordination geometry is noted in (II), arising as a result of quite disparate Sn-S bond lengths. Here, the four S-donors define a trapezoidal plane with the ipso-C atoms lying over the weaker of the Sn-S bonds so that the C₂S₄ donor set defines a skewed trapezoidal bipyramid. The packing of (I) features supramol. layers in the ab plane sustained by methylene-C-H···π(Sn-aryl) interactions. In (II), supramol. chains along the b-axis direction are formed by methylene-C-O(ether) interactions; these pack with no directional interactions between them. A Hirshfeld surface anal. was conducted on both (I) and (II) and revealed the dominance of H···H interactions contributing to the resp. surfaces, i.e. >60% in each case, and other features consistent with the description of the mol. packing above.

38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Name: 2-Methoxy-N-methylethanamine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem