Category: 101-84-8

Recently I am researching about PRENATAL EXPOSURE; FETAL-GROWTH; CORD BLOOD; PERFLUOROALKYL SUBSTANCES; POLYCHLORINATED-BIPHENYLS; GENES; PBDES; SERUM; PCBS; AGE, Saw an article supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health [HHSN275200800013C, HHSN275200800002I, HHSN27500006, HHSN275200800003IC, HHSN275200800014C, HHSN275200800012C, HHSN275200800028C, HHSN275201000009C, HHSN27500008, HHSN2752911999911]; National Institute on Minority Health and Health DisparitiesUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute on Minority Health & Health Disparities (NIMHD); National Institute of Diabetes and Digestive and Kidney DiseasesUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK); NIH Office of the DirectorUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA. Safety of Diphenyl oxide. Published in BMC in LONDON ,Authors: Ouidir, M; Mendola, P; Louis, GMB; Kannan, K; Zhang, CL; Tekola-Ayele, F. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide

Background Prenatal maternal plasma persistent organic pollutant (POP) concentrations have been associated with neonatal outcomes. However, the underlying mechanisms remain unknown. Placental epigenetic mechanisms may be involved, but no prior epigenome-wide studies have investigated the impact of maternal POPs on placental DNA methylation. We studied the association between maternal plasma POP concentration in early pregnancy and epigenome-wide placental DNA methylation among 260 pregnant women from the NICHD Fetal Growth Studies. Results Our analysis focused on POPs with more than 80% plasma concentrations above the limit of quantification, including 3 organochlorine pesticides (hexachlorobenzene, trans-nonachlor,p,p’-dichlorodiphenyldichloroethylene), 1 polybrominated diphenyl ether (PBDE 47), 3 polychlorinated biphenyls (138/158, 153, 180), and 6 poly- and perfluorinated alkyl substances (PFASs) (perfluorodecanoic acid, perfluorohexanesulfonic acid, perfluorononanoic acid, perfluorooctanesulfonic acid, perfluoroundecanoic acid (PFUnDA)). Using 5% false discovery rate, POPs were associated with a total of 214 differentially methylated CpG sites (nominalpvalues ranging from 2.61 x 10(-21)to 2.11 x 10(-7)). Out of the 214 CpG sites, 24 (11%) were significantly correlated with placental expression of 21 genes. Notably, higher PFUnDA was associated with increased methylation at 3 CpG sites (cg13996963, cg12089439, cg18145877) annotated toTUSC3, and increased methylation at those 3 CpG sites was correlated with decreased expression ofTUSC3in the placenta. Increased methylation at cg18145877 (TUSC3) and decreased expression ofTUSC3were correlated with shorter birth length. Out of the 214 CpG sites, methylation at 44 CpG sites was correlated (pvalue < 0.10) with at least one neonatal anthropometry measure (i.e., birth weight, birth length, and head circumference). Seven CpG sites mediated (pvalue < 0.05) the association between PBDE 47 and neonatal anthropometry measures. Genes annotating the top differentially methylated CpG sites were enriched in pathways related to differentiation of embryonic cells (PBDE 47) and in pathways related to brain size and brain morphology (PFASs). Conclusions DNA methylation changes in the placenta were significantly associated with maternal plasma POPs concentration. The findings suggest that placental DNA methylation and gene expression mechanism may be involved in the prenatal toxicity of POPs and their association with neonatal anthropometry measures. Safety of Diphenyl oxide. Welcome to talk about 101-84-8, If you have any questions, you can contact Ouidir, M; Mendola, P; Louis, GMB; Kannan, K; Zhang, CL; Tekola-Ayele, F or send Email.

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In 2019 ECOTOX ENVIRON SAFE published article about VALIDATION; TOOL; PREDICTIONS; ENVIRONMENT; REGRESSION; SOFTWARE; HAZARD; WATER in [Khan, Kabiruddin; Roy, Kunal] Jadavpur Univ, Dept Pharmaceut Technol, 188 Raja SC Mullick Rd, Kolkata 700032, India; [Benfenati, Emilio; Roy, Kunal] Ist Ric Farmacol Mario Negri IRCCS, Lab Environm Chem & Toxicol, Via La Masa 19, I-20156 Milan, Italy in 2019, Cited 39. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. Computed Properties of C12H10O

In the present work, quantitative structure-activity relationship (QSAR) models have been developed for ecotoxicity of pharmaceuticals on four different aquatic species namely Pseudokirchneriella subcapitata, Daphnia magna, Oncorhynchus mykiss and Pimephales promelas using genetic algorithm (GA) for feature selection followed by Partial Least Squares regression technique according to the Organization for Economic Co-operation and Development (OECD) guidelines. Double cross-validation methodology was employed for selecting suitable models. Only 2D descriptors were used for capturing chemical information and model building, whereas validation of the models was performed by considering various stringent internal and external validation metrics. Interestingly, models could be developed even without using any LogP terms in contrary to the usual dependence of toxicity on lipophilicity. However, the current manuscript proposes highly robust and more predictive models employing computed logP descriptors. The applicability domain study was performed in order to set a pre-defined chemical zone of applicability for the obtained QSAR models, and the test compounds falling outside the domain were not taken for further analysis while making a prioritized list. An additional comparison was made with ECOSAR, an online expert system for toxicity prediction of organic pollutants, in order to prove predictability of the obtained models. The obtained robust consensus models were utilized to predict the toxicity of a large dataset of approximately 9300 drug-like molecules in order to prioritize the existing drug-like substances in accordance to their acute predicted aquatic toxicities following a scaling technique. Finally, prioritized lists of 500 most toxic chemicals obtained by respective consensus models and those predicted from ECOSAR tool have been reported.

Computed Properties of C12H10O. Welcome to talk about 101-84-8, If you have any questions, you can contact Khan, K; Benfenati, E; Roy, K or send Email.

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Hoang, AQ; Takahashi, S; Le, ND; Duong, TT; Pham, TMH; Pham, TNM; Nguyen, TAH; Tran, TM; Tu, MB; Le, TPQ in [Anh Quoc Hoang; Takahashi, Shin] Ehime Univ, Ctr Adv Technol Environm, Grad Sch Agr, 3-5-7 Tarumi, Matsuyama, Ehime 7908566, Japan; [Anh Quoc Hoang; Thi Ngoc Mai Pham; Thi Anh Huong Nguyen; Tri Manh Tran; Minh Binh Tu] Vietnam Natl Univ, Univ Sci, Fac Chem, 19 Le Minh Tong, Hanoi 10000, Vietnam; [Nhu Da Le; Thi Phuong Quynh Le] Vietnam Acad Sci & Technol, Inst Nat Prod Chem, Lab Environm Chem, 18 Hoang Quoc Viet, Hanoi 10000, Vietnam; [Nhu Da Le; Thi Phuong Quynh Le] Vietnam Acad Sci & Technol, Grad Univ Sci & Technol, 18 Hoang Quoc Viet, Hanoi 10000, Vietnam; [Thi Thuy Duong] Vietnam Acad Sci & Technol, Inst Environm Technol, 18 Hoang Quoc Viet, Hanoi 10000, Vietnam; [Thi Mai Huong Pham] Hanoi Univ Ind, 298 Cau Dien, Hanoi 10000, Vietnam published Comprehensive determination of polychlorinated biphenyls and brominated flame retardants in surface sediment samples from Hanoi urban area, Vietnam: Contamination status, accumulation profiles, and potential ecological risks in 2021.0, Cited 70.0. Name: Diphenyl oxide. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8.

Comprehensive and updated information about polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs) in surface sediments from Hanoi, the capital city of Vietnam, is rather scarce. In this study, concentrations and profiles of 209 PCBs, 41 polybrominated diphenyl ethers (PBDEs), 2,2 ‘,4,4 ‘,5,5 ‘-hexabromobiphenyl (BB-153), hexabromocyclododecane (HBCD), pentabromoethylbenzene (PBEB), 1,2-bis(2,4,6tribromophenoxy)ethane (BTBPE), and decabromodiphenyl ethane (DBDPE) were determined in sediment samples collected from the Red River and some inner-city rivers of Hanoi. Concentrations (ng/g dry weight, median and range) of pollutants decreased in the order: DBDPE (28; not detected ND – 59) approximate to PCBs (27; 1.7-50) > PBDEs (23; 0.20-61) > HBCD (1.2; ND – 5.2) > BTBPE (0.46; ND – 3.6) > BB-153 (0.004; ND – 0.014) > PBEB (ND). Pollutant levels in the inner-city river sediments were about one to two orders of magnitude higher than those measured in the Red River main stream sediments. Tri-to hexa-CBs are major homologs but detailed profiles vary between individual samples, reflecting source and/or seasonal variations. CB-11 and CB-209 were found at higher proportions in sediments than in technical PCB mixtures, suggesting their novel sources from pigments. Deca-BDE and DBDPE are the most predominant BFRs with an increasing trend predicted for DBDPE. A preliminary ecological risk assessment was conducted for these pollutants in sediments. Total PCBs and deca-BDE in a few inner-city river sediments may exhibit adverse effects on benthic organisms, but no serious risk was estimated in general.

Name: Diphenyl oxide. Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.

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Ether – Wikipedia,
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Category: ethers-buliding-blocks. Recently I am researching about AGGREGATION-INDUCED EMISSION; CATALYZED CARBOARYLATION; REARRANGEMENT; ALKYNES; C-14; TETRAPHENYLETHENE; EFFICIENT; VESICLES; OLEFINS; CATIONS, Saw an article supported by the Ecole Polytechnique Federale de Lausanne (EPFL); Swiss National Science FoundationSwiss National Science Foundation (SNSF)European Commission. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Suleymanov, AA; Doll, M; Ruggi, A; Scopelliti, R; Fadaei-Tirani, F; Severin, K. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide

Tetraarylethenes are obtained by acid-induced coupling of vinyl triazenes with aromatic compounds. This new C-H activation route for the synthesis of aggregation-induced emission luminogens is simple, fast, and versatile. It allows the direct grafting of triarylethenyl groups onto a variety of aromatic compounds, including heterocycles, supramolecular hosts, biologically relevant molecules, and commercial polymers.

Category: ethers-buliding-blocks. Welcome to talk about 101-84-8, If you have any questions, you can contact Suleymanov, AA; Doll, M; Ruggi, A; Scopelliti, R; Fadaei-Tirani, F; Severin, K or send Email.

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Authors Wan, NN; Zhuo, CY; Qiao, L; Gong, J; Yang, Y; Ran, Y in TAYLOR & FRANCIS INC published article about PEARL RIVER DELTA; POLYCYCLIC AROMATIC-HYDROCARBONS; POLYBROMINATED DIPHENYL ETHERS; CONTAMINATION; GROUNDWATER; QUALITY; DROUGHT; TRENDS; WASTE; CORES in [Wan, Nannan; Zhuo, Chenya; Qiao, Lei; Yang, Yu; Ran, Yong] Chinese Acad Sci, Guangzhou Inst Geochem, State Key Lab Organ Geochem, Guangzhou, Peoples R China; [Wan, Nannan; Zhuo, Chenya; Qiao, Lei; Yang, Yu; Ran, Yong] Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Prov Key Lab Environm Protect & Resourc, Guangzhou, Peoples R China; [Wan, Nannan; Zhuo, Chenya; Qiao, Lei] Univ Chinese Acad Sci, Beijing, Peoples R China; [Gong, Jian] Guangzhou Univ, Sch Environm Sci & Engn, Guangdong Prov Key Lab Radionuclides Pollut Contr, Guangzhou, Peoples R China in 2020.0, Cited 37.0. Safety of Diphenyl oxide. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8

Polybrominated diphenyl ethers (PBDEs) and polycyclic aromatic hydrocarbons (PAHs) were detected by gas chromatography-mass spectrometry in the sediment core form Poyang Lake. The concentrations of sigma 17 PBDEs and sigma 15 PAHs ranged from 1.13 to 4.64 ng/g, and from 341 to 744 ng/g, respectively. The Rock-Eval test was conducted to obtain organic matter parameters such as total organic carbon (TOC), S2, and hydrogen index (HI). The value of TOC, S2, and HI showed an increasing trend from the bottom to the surface. Source analysis results showed that the source of PAHs was combustion. Moreover, the correlation analysis of PBDEs, PAHs, and annual average temperature with S2 and HI showed that BDE-202, BDE-201, BDE-183, and BDE-154 were negatively correlated with S2 and HI, while BDE-85 and BDE-47 were positively correlated. There was no significant correlations of PAHs with S2 and HI, which is related to the disturbance of sediments. It is interesting that significantly positive correlation of HI with five-year moving averages of the air temperature was demonstrated, demonstrating that the climate warming enhanced the increase of algae in the Poyang Lake.

Safety of Diphenyl oxide. Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.

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Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Quality Control of Diphenyl oxide. Authors Wu, D; Wang, QY; Safonova, OV; Peron, DV; Zhou, WJ; Yan, Z; Marinova, M; Khodakov, AY; Ordomsky, VV in WILEY-V C H VERLAG GMBH published article about in [Wu, Dan; Wang, Qiyan; Zhou, Wenjuan; Yan, Zhen] CNRS Solvay, UMI 3464, Ecoefficient Prod & Proc Lab E2P2L, Shanghai 201108, Peoples R China; [Wu, Dan; Wang, Qiyan; Peron, Deizi, V; Khodakov, Andrei Y.; Ordomsky, Vitaly V.] Univ Lille, Univ Artois, CNRS, Cent Lille,ENSCL,UMR 8181,UCCS Unite Catalyse & C, F-59000 Lille, France; [Marinova, Maya] Univ Lille, Univ Artois, CNRS, INRAE,Cent Lille,FR2638,IMEC Inst Michel Eugene C, F-59000 Lille, France; [Safonova, Olga, V] Paul Scherrer Inst, CH-5253 Villigen, Switzerland in 2021.0, Cited 67.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8

The cleavage of C-O linkages in aryl ethers in biomass-derived lignin compounds without hydrogenation of the aromatic rings is a major challenge for the production of sustainable mono-aromatics. Conventional strategies over the heterogeneous metal catalysts require the addition of homogeneous base additives causing environmental problems. Herein, we propose a heterogeneous Ru/C catalyst modified by Br atoms for the selective direct cleavage of C-O bonds in diphenyl ether without hydrogenation of aromatic rings reaching the yield of benzene and phenol as high as 90.3 % and increased selectivity to mono-aromatics (97.3 vs. 46.2 % for initial Ru) during depolymerization of lignin. Characterization of the catalyst indicates selective poisoning by Br of terrace sites over Ru nanoparticles, which are active in the hydrogenation of aromatic rings, while the defect sites on the edges and corners remain available and provide higher intrinsic activity in the C-O bond cleavage.

Welcome to talk about 101-84-8, If you have any questions, you can contact Wu, D; Wang, QY; Safonova, OV; Peron, DV; Zhou, WJ; Yan, Z; Marinova, M; Khodakov, AY; Ordomsky, VV or send Email.. Quality Control of Diphenyl oxide

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Ether – Wikipedia,
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Recently I am researching about BENZYNE-CLICK CHEMISTRY; FACILE N-ARYLATION; O-ARYLATION; NUCLEOPHILIC-SUBSTITUTION; SELECTIVE SYNTHESIS; GENERATION; EFFICIENT; PHENOLS; MAGNESIUM; REAGENTS, Saw an article supported by the Sao Paulo Research Foundation (FAPESP)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2017/21990-0]; National Council for Scientific and Technological Development (CNPq)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ); Coordination for the Improvement of Higher Education Personnel (CAPES)Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES); FAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2016/10894-7]. Application In Synthesis of Diphenyl oxide. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Muraca, ACA; Raminelli, C. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide

A class of aryne precursors, that is, 2-(trimethylsilyl)aryl 4-chlorobenzenesulfonates, has been developed through well-established synthetic routes, which allow the formation of arynes under relatively mild conditions. All the aryne precursors were obtained from phenols and 4-chlorobenzenesulfonyl chloride, an inexpensive and easy-to-handle reagent with relatively low toxicity, and subjected to nucleophilic addition reactions, providing addition products in yields of 24 to 92%, and to cycloaddition reactions, affording cycloadducts in yields up to 80%. This work provides interesting insights into the mechanisms of aryne generation. In addition, 2-(trimethylsilyl)phenyl 4-chlorobenzenesulfonate was successfully employed in the total synthesis of (+/-)-aporphine.

Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.. Application In Synthesis of Diphenyl oxide

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HPLC of Formula: C12H10O. I found the field of Chemistry very interesting. Saw the article Para-selective borylation of monosubstituted benzenes using a transient mediator published in 2020, Reprint Addresses Wang, P (corresponding author), Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China.; Wang, P (corresponding author), Shanghai Inst Organ Chem, CAS Key Lab Energy Regulat Mat, Shanghai 200032, Peoples R China.; Peng, Q (corresponding author), Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide.

Herein, we conceptualized a transient mediator approach that has the capability of para-selective C-H functionalization of monosubstituted aromatics. This approach is enabled by in situ generation of a versatile sulfonium salt via highly electrophilic phenoxathiine or thianthrene dication intermediate which can be readily generated from its sulfoxide with tri-fluoromethanesulfonic anhydride. Preliminary mechanistic study implied that the remarkable para selectivity might be related to the incredible electrophilicity of thianthrene dication intermediate. The versatility of this approach was demonstrated via para-borylation of various monosubstituted simple aromatics combining the sulfonium salt formation with further photocatalyzed transformation.

HPLC of Formula: C12H10O. Welcome to talk about 101-84-8, If you have any questions, you can contact Wu, J; Wang, ZW; Chen, XY; Wu, YC; Wang, DM; Peng, Q; Wang, P or send Email.

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Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Li, C; Yang, LL; Shi, MW; Liu, GR in [Li, Cui; Yang, Lili; Liu, Guorui] Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China; [Li, Cui; Yang, Lili; Liu, Guorui] Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100190, Peoples R China; [Shi, Miwei] Hebei Acad Sci, Inst Geog Sci, Hebei Engn Res Ctr Geog Informat Applicat, Shijiazhuang 050051, Hebei, Peoples R China published Persistent organic pollutants in typical lake ecosystems in 2019.0, Cited 86.0. Recommanded Product: 101-84-8. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8.

Persistent organic pollutants (POPs) are highly toxic organic chemicals. Lakes are one of the main sinks of POPs. POPs can be accumulated in multiple matrices in lake ecosystems and biomagnified through the food web, and thus pose a potential threat not only to lake ecosystems, but also to human health. Given their potential persistent risks, they have received much attention over the past decades. This review comprehensively summarizes the data on the levels and distributions of POPs in selected typical lake ecosystems in China and worldwide, involving water, sediments, organisms, and surrounding soils and atmosphere. It was found that current publications on POPs in Chinese lakes are mainly related to lakes in the developed eastern plain area, with only a few studies concerning the less-developed Qinghai-Tibet Plateau area. Similarly, around the world, there are more research on POPs in developed countries and less in relatively less-developed areas. Moreover, there are significant differences in the levels of POPs in different matrices in different lake ecosystems. Legacy POPs, such as polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), and polybrominated diphenyl ethers (PBDEs), were commonly detected and reported in different lakes, while emerging POPs like perfluorinated compounds (PFCs), polychlorinated naphthalenes (PCNs), Tetrabromobisphenol A (TBBPA), and hexabromocyclododecane (HCBD) were relatively less detected or reported. A comprehensive summarization on the levels and distributions of traditional and emerging POPs in lake ecosystems could be significant for further understanding the behaviors and risks of POPs in lake ecosystems.

Recommanded Product: 101-84-8. Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.

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Ether – Wikipedia,
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Recently I am researching about VASCULAR DISRUPTING AGENTS; INHIBITORS; COMPLEX; DESIGN, Saw an article supported by the Spanish Ministerio de Economia y Competitividad [SAF2015-64629-C2-1-R, BFU2016-75319-R]; CSIC (Proyecto Intramural) [PIE-201668E079]. Published in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER in ISSY-LES-MOULINEAUX ,Authors: Bueno, O; Gargantilla, M; Estevez-Gallego, J; Martins, S; Diaz, JF; Camarasa, MJ; Liekens, S; Perez-Perez, MJ; Priego, EM. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide. Computed Properties of C12H10O

Microtubule targeting agents represent a very active arena in the development of anticancer agents. In particular, compounds binding at the colchicine site in tubulin are being deeply studied, and the structural information recently available on this binding site allows structure-directed design of new ligands. Structural comparison of our recently reported high resolution X-Ray structure of the cyclohexanedione derivative TUB075 bound to tubulin and the tubulin-DAMA-colchicine complex has revealed a conformational change in the alpha T5 loop. By a grid-based computational analysis of the tubulin-DAMA-colchicine binding site, we have identified a new favourable binding area in the colchicine-site that was unexplored by our lead TUB075. Thus, based on a structure-guided design, new cyclohexanedione derivatives have been synthesized and tested for tubulin binding and in cellular assays. As a result, we have identified diphenyl ether derivatives with IC50 values around 10-40 nM against three different tumor cell lines and affinity constants for tubulin similar to that of colchicine around 10(7) M-1. As expected, they halted the cell cycle progression at G2/M phase at concentrations as low as 0.08 mu M. (C) 2019 Elsevier Masson SAS. All rights reserved.

Computed Properties of C12H10O. Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.

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Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem