Category: 2380-78-1

Sustainable Process for the Depolymerization/oxidation of softwood and hardwood kraft lignins using hydrogen peroxide under ambient conditions was written by Ahmad, Zaid;Al Dajani, Waleed Wafa;Paleologou, Michael;Xu, Chunbao Charles. And the article was included in Molecules in 2020.Quality Control of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

The present study demonstrated a sustainable and cost-effective approach to depolymerize/oxidize softwood (SW) and hardwood (HW) kraft lignins using concentrated hydrogen peroxide at temperatures ranging from 25 to 35°C, in the absence of catalysts or organic solvents. The degree of lignin depolymerization could be simply controlled by reaction time, and no further separation process was needed at the completion of the treatment. The obtained depolymerized lignin products were comprehensively characterized by GPC-UV, FTIR, ³¹P-NMR, TGA, Py-GC/MS and elemental anal. The weight-average mol. weights (M_w) of the depolymerized lignins obtained from SW or HW lignin at a lignin/H₂O₂ mass ratio of 1:1 after treatment for 120 h at room temperature (≈25°C) were approx. 1420 Da. The contents of carboxylic acid groups in the obtained depolymerized lignins were found to significantly increase compared with those of the untreated raw lignins. Moreover, the depolymerized lignin products had lower thermal decomposition temperatures than those of the raw lignins, as expected, owing to the greatly reduced M_w. These findings represent a novel solution to lignin depolymerization for the production of chems. that can be utilized as a bio-substitute for petroleum-based polyols in polyurethane production This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Quality Control of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Influence of Diet-Induced Obesity on the Bioavailability and Metabolism of Raspberry Ketone (4-(4-Hydroxyphenyl)-2-Butanone) in Mice was written by Zhao, Danyue;Yuan, Bo;Kshatriya, Dushyant;Polyak, Andrew;Simon, James E.;Bello, Nicholas T.;Wu, Qingli. And the article was included in Molecular Nutrition & Food Research in 2020.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Raspberry ketone (RK) is the primary aroma compound in red raspberries and a dietary supplement for weight loss. This work aims to (1) compare RK bioavailability in male vs. female, normal-weight vs. obese mice; (2) characterize RK metabolic pathways. Study 1: C57BL/6J male and female mice fed a low-fat diet (LFD; 10% fat) receive a single oral gavage dose of RK (200 mg kg^-1). Blood, brain, and white adipose tissue (WAT) are collected over 12 h. Study 2: Male mice are fed a LFD or high-fat diet (45% fat) for 8 wk before RK dosing. Samples collected are analyzed by UPLC-MS/MS for RK and its metabolites. RK is rapidly absorbed (T_max ≈ 15 min), and bioconverted into diverse metabolites in mice. Total bioavailability (AUC_0-12h) is slightly lower in females than males (566 vs 675 nmol mL^-1 min^-1). Total bioavailability in obese mice is almost doubled that of control mice (1197 vs 679 nmol mL^-1 min^-1), while peaking times and elimination half-lives are delayed. Higher levels of RK and major metabolites are found in WAT of the obese than normal-weight animals. RK is highly bioavailable, rapidly metabolized, and exhibits significantly different pharmacokinetic behaviors between obese and control mice. Lipid-rich tissues, especially WAT, can be a direct target of RK. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Efficient Utilization and Conversion of Whole Components in Waste Biomass with One-Pot-Oriented Liquefaction was written by Feng, Junfeng;Tong, Le;Zhu, Yanqi;Jiang, Jianchun;Hse, Chungyun;Pan, Hui. And the article was included in ACS Sustainable Chemistry & Engineering in 2019.Computed Properties of C9H12O3 The following contents are mentioned in the article:

A simple oriented liquefaction with microwave assistance was introduced to produce phenolic compounds and cellulose nanofibers from the comprehensive utilization of biomass. Effects of process parameters on the yield and composition of liquefied straw products were investigated. Liquefied products was separated into liquid and solid products. The highest phenolics content (72.87%) in liquid products was achieved; the yield of nanofibers from liquefied solid products was 47.43 wt %. With stepwise extraction, phenolics with nice reactivity were largely separated into three fractions. They were mainly composed of phenolic compounds and aromatic derivatives and had good solubility in organic solvents. After a chem.-purified treatment, solid products containing highly crystalline cellulose were converted into nanofibers with good application. These simple processes achieve a comprehensive use of liquefied products to various synthetical directions based on different mol. structures and chem. solubility Directional liquefaction was significantly effective to produce renewable phenolics and nanofibers and realizes the integrated valorization of whole components in waste biomass. Oriented liquefaction with microwave assistance to produce phenolic compounds and cellulose nanofibers from the comprehensive utilization of biomass is discussed. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Computed Properties of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Microwave Assisted Depolymerization of Alkaline Lignin over Hydrotalcite-Based CuNiAl Mixed Oxides was written by Zhou, Minghao;Sharma, Brajendra K.;Liu, Peng;Xia, Haihong;Xu, Junming;Jiang, Jian-chun. And the article was included in ACS Sustainable Chemistry & Engineering in 2018.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

In this study, microwave assisted depolymerization of alk. lignin into bio-oil was investigated in the presence of CuNiAl hydrotalcite based solid base catalysts in methanol. The effects of catalysts, reaction temperature, time, and heating methods were all studied in detail to improve the bio-oil yield. The promotion effect of microwave heating and Cu amount in the CuNiAl based catalysts was obviously observed during degradation of lignin, leading to improved bio-oil yield and lower mol. weight The highest yield of bio-oil was up to 60.1%, when the depolymerization was conducted at 160 °C for 80 min over CuNiAl based catalyst (metal ratio of 1.5:4.5:2). The monomers and oligomers were identified by GC-MS and MALDI-TOF MS, finding p-hydroxyacetophenone (H2), guaiacol (G1), p-hydroxyacetovanillon (G5), and syringaldehyde (S3) as the main monophenols in bio-oil. The possible chem. structures for oligomers with mol. weight of 288 m/z, 306 m/z, 316 m/z, 330 m/z, 412 m/z, 426 m/z, and 456 m/z were obtained, and plausible depolymerization pathways were proposed in order to facilitate the understanding of possible relationship for the formation of prominent oligomers and monomers. This study confirmed that heterogeneous base catalysts coupled with microwave heating could provide a promising technique to convert lignin to liquid fuels. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Deep catalytic hydroconversion of straw-derived bio-oil to alkanes over mesoporous zeolite Y supported nickel nanoparticles was written by Kang, Yu-Hong;Wei, Xian-Yong;Zhang, Xiao-Qi;Li, Yan-Jun;Liu, Guang-Hui;Ma, Xiang-Rong;Li, Xiao;Bai, Hong-Cun;Li, Zhen-Ni;Yan, Hai-Jun;Zong, Zhi-Min. And the article was included in Renewable Energy in 2021.Recommanded Product: 2380-78-1 The following contents are mentioned in the article:

A supported nickle catalyst was prepared by loading ca. 11% of nickel nanoparticles (NNPs) on mesoporous zeolite Y (MZY) and denoted as Ni11%/MZY. A straw was methanolyzed at 300 °C to obtain methanol-soluble portion as a straw-derived bio-oil (SDBO) in the yield of 19.3%. According to the anal. with a gas chromatograph/mass spectrometer, SDBO consists of arenes (7.8%), oxygen-containing organic compounds (82.8%), nitrogen-containing organic compounds (6.3%), and sulfur-containing organic compounds (3.1%). It was subjected to catalytic hydroconversion (CHC) over Ni11%/MZY in n-hexane under 5 MPa of initial hydrogen pressure (IHP) at 160 °C for 16 h. As a result, all the compounds in SDBO were converted to chain alkanes (60.1%) and cyclanes (39.9%). In Ni11%/MZY, uniformly dispersed NNPs and strong Lewis acid sites in the defective crystal texture of MYZ play crucial roles in hydrogenating aromatic rings and removing heteroatoms (HAs), resp. Benzyloxybenzene (BOB) was used as a lignin-related model compound The main product from the CHC of BOB over Ni11%/MZY in n-hexane under 5 MPa of IHP at 160 °C for 2 h is methylcyclohexane in the yield of 90.9%, indicating that both hydrogenation of benzene rings and deoxygenation significantly proceeded. After being recycled 4 times, Ni11%/MZY is still active for the CHC of BOB. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Influence of pre-fermentative addition of aqueous solution tannins extracted from oak wood (Quercus petraea) on the composition of Grillo wines was written by Corona, Onofrio;Bambina, Paola;De Filippi, Diego;Cinquanta, Luciano. And the article was included in European Food Research and Technology in 2021.Recommanded Product: 2380-78-1 The following contents are mentioned in the article:

In this research, the chem. characterization of fixed and volatile compounds of two different tannins in aqueous solution (Pratiko L-Harvest and L-Fruit) extracted from oak wood, has been studied. The influence of the above tannins, at different concentrations, on the alc. fermentation kinetics and on the composition and sensorial characteristics of a white wine were then evaluated. The wines added tannins in aqueous solution compared to control wines showed significant differences in fixed compounds (colloids, polyphenols and ellagitannins) and volatile compounds (phenolic aldehydes, volatile phenols, furanic and piranic compounds). The differences of aqueous solution tannins extracted from oak wood were partly due to the drying/maturing and roasting methods used in barrel production Alc. fermentation was partially facilitated by the addition of tannins in aqueous solution The wines obtained showed a higher content of Et esters of medium-chain fatty acids (from 22 to 31%) and, in some cases, higher acetate alcs. (from 15 to 28%), relevant to the olfactory sensations provided to the wines. The tannins added to the must before fermentation also made it possible to obtain an addnl. supply of polyphenols (from 25 to 85%) able to induce more complex sensory profiles in the wines, with increased persistent taste notes. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Natural Product Phenolic Diglycosides Created from Wildfires, Defining Their Impact on California and Oregon Grapes and Wines was written by Crews, Phillip;Dorenbach, Paul;Amberchan, Gabriella;Keiffer, Ryan F.;Lizama-Chamu, Itzel;Ruthenburg, Travis C.;McCauley, Erin P.;McGourty, Glenn. And the article was included in Journal of Natural Products in 2022.Reference of 2380-78-1 The following contents are mentioned in the article:

Forest fires produce malodorous phenols, bioaccumulated in grapes as odorless phenol glycosides (mono- to tri-), and produce unpleasant smoke tainted wines when these complexes are transformed by glycosidases in saliva. Metabolomic analyses were used to further understand smoke taint by quantitating marker phenolic diglycosides via UHPLC separations and MS/MS multiple reaction monitoring. A collection of grapes and wines provided data to forecast wine quality of grapes subjected to wildfire smoke infestations; the analytics used a panel of reference compounds (1-6). Overall, eight different Vitis vinifera varietals were examined from 2017-2021 vintages involving >218 distinct samples (wines and/or grapes) from 21 different American Viticulture Areas. Results acquired allowed correlation of phenolic diglycoside levels as a function of grape cultivar, varietal clones, and intensity of wildfire smoke. Baseline data were tabulated for nonsmoked samples (especially, Cabernet Sauvignon having a sum 1-6 of <6μg/L) and then compared to those exposed to six other levels of smoke. Outcomes established that (1) analyzing paired samples (bottled wines vs. smoke-exposed grapes) can provide diagnostic metabolomic data, (2) phenolic diglycosides are stable in wines aged for >2.5 years, and (3) major gaps exist in our current understanding of this pool of metabolites. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Reference of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties was written by Choi, Wonbeen;Villegas, Valente;Istre, Hannah;Heppler, Ben;Gonzalez, Niki;Brusman, Nicole;Snider, Lindsey;Hogle, Emily;Tucker, Janelle;Onate, Alma;Onate, Sandra;Ma, Lili;Paula, Stefan. And the article was included in Bioorganic Chemistry in 2019.Application of 2380-78-1 The following contents are mentioned in the article:

Inhibitors of the enzyme xanthine oxidase (XO) with radical scavenging properties hold promise as novel agents against reperfusion injuries after ischemic events. By suppressing the formation of damaging reactive oxygen species (ROS) by XO or scavenging ROS from other sources, these compounds may prevent a buildup of ROS in the aftermath of a heart attack or stroke. To combine these two properties in a single mol., we synthesized and characterized the non-purine XO inhibitor caffeic acid phenethylester (CAPE) and 19 derivatives using a convenient microwave-assisted Knoevenagel condensation protocol. Varying systematically the number and positions of the hydroxyl groups at the two Ph rings, we derived structure-activity relationships based on exptl. determined XO inhibition data. Mol. docking suggested that critical enzyme/inhibitor interactions involved π-π interactions between the phenolic inhibitor ring and Tyr914, hydrogen bonds between inhibitor hydroxyl groups and Glu802, and hydrophobic interactions between the CAPE Ph ring and non-polar residues located at the entrance of the binding site. To effectively scavenge the stable radical DPPH, two hydroxyl groups in 1,2- or 1,4-position at the Ph ring were required. Among all compounds tested, E-Ph 3-(3,4-dihydroxyphenyl)acrylate, a CAPE analog without the Et tether, showed the most promising properties. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hydrothermal processing of waste pine wood into industrially useful products was written by Gokhale, Jyoti S.;Hude, Moreshwar P.;Yadav, Ganapati D.;Thomas, Morgan;Kozinski, Janusz;Dalai, Ajay K.. And the article was included in Journal of the Indian Chemical Society in 2022.Related Products of 2380-78-1 The following contents are mentioned in the article:

An ongoing major outbreak of mountain pine beetle in Western Canada has provided a clear opportunity to utilize waste pinewood as a source of renewable energy. Therefore hydrothermal processing of waste pinewood as a feedstock for bio-oil and biochar production using subcritical and supercritical water technol. was carried out in semi-batch mode to investigate the effect of pressure (200-400 bar) and temperature (300-400°C) on the yield and composition of bio-oil. The pinewood samples have very high cellulose and hemicellulose content but low ash content and are thus a formidable feedstock for bioenergy production The optimum conditions for the hydrothermal processing of the pinewood in a tubular reactor were found to be 400°C and 250 bars with respect to biochar and bio-oil yield based on the highest calorific value anal. Detailed characterization of bio-oil and biochar was performed using GCMS, NMR, SEM, calorific value and elemental anal., resp. The critical components of bio-oil were found to be phenols, methoxyphenols, hydroxymethyl furfural (HMF) and vanillin, whereas as compared to the raw pine wood, the biochar was considerably lower H:C and O:C ratios than those of the unprocessed pinewood. The analyzes of bio-oil by means of GCMS and ¹H NMR showed that it was mainly composed of heterocyclic compounds, phenols, aldehydes and acids. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Related Products of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chemical structure of semiochemicals and key binding sites together determine the olfactory functional modes of odorant-binding protein 2 in Eastern honey bee, Apis cerana was written by Li, Hong-Liang;Song, Xin-Mi;Wu, Fan;Qiu, Yi-Lei;Fu, Xiao-Bin;Zhang, Lin-Ya;Tan, Jing. And the article was included in International Journal of Biological Macromolecules in 2020.Quality Control of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Insects can exhibit flexible olfaction that is sensitive to complex natural chem. environments. Odorant-binding proteins (OBPs) in insects’ antennal chemosensilla can act as transporters of plant volatiles and pheromones across the sensillar lymph. Although the physiol. functions of OBPs have been widely reported, it is still unclear how OBP binds to ligands with various structures in detail. Here, we further investigated the ligand-binding modes and characteristics of AcerOBP2 from the Eastern honey bee (Apis cerana). The results showed that, as a specific protein distributed below the base of chemosensilla on the antennal surface, AcerOBP2 was strongly bound with the candidate floral volatiles and bee pheromones. By docking anal. and site-directed mutagenesis, four different binding modes were found in the five AcerOBP2 mutants between six ligands. Two key amino acids, Ser123 and Lys51, play a key role in AcerOBP2 binding to odors, depending on the presence or absence of hydrogen bonds. In addition, the binding modes depend on their chem. structures and the binding poses of the diverse ligands. These results not only further prompted the functional basis of the relationship between the chem. structures of odorants and bee OBPs, but also revealed the complexity of the flexible behavioral modes of odor binding in insect olfactory systems. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Quality Control of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem