Category: 2380-78-1

Extrapolation of hydroxytyrosol and its analogues as potential anti-inflammatory agents was written by Kumar, Naresh;Gorai, Biswajit;Gupta, Saurabh;Shiva;Goel, Nidhi. And the article was included in Journal of Biomolecular Structure and Dynamics in 2021.Related Products of 2380-78-1 The following contents are mentioned in the article:

Discovery of potential lead mol. is a challenging, and complex process which require lots of money, patience, and manpower. Human beings are using natural products, predominantly secondary metabolites, for this purpose since ancient time and they are still working on them as a potent source for drug discovery due to their wide structural diversity. Phenolic phytochems. such as hydroxytyrosol and tyrosol are natural antioxidant and involved in many biol. disease cure. Herein, we have carried out the quantum chem. calculations for conformational anal., geometry optimization and computation of electronic as well as optical properties of hydroxytyrosol and its analogs (1a-1k) in terms of d. functional theory by using Gaussian 09 program suite. The eventual charge transfer within the mols. has been confirmed by the anal. of frontier MOs. The mol. docking studies of 1a-1k with cyclooxygenase-2 showed the noticeable binding affinity as compared to other nonsteroidal anti-inflammatory drugs viz. aspirin, naproxen and celecoxib. Computation of pharmacokinetics and pharmacol. properties confirmed the lead/drug like potential of these screened mols. Furthermore, the mol. dynamics simulation of best three docked ligands (1f, 1h and 1k)-receptor complex and their binding free energy calculations reveals that these mols. bind in the catalytic cavity of cyclooxygenase-2 and found stable during the 100 ns of simulation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Related Products of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 2380-78-1

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalytic upgrading of Kraft lignin derived bio-oil in supercritical ethanol over different crystal size hierarchical nano-HZSM5 was written by Agarwal, Ashutosh;Park, Seong-Jae;Park, Jeong-Hun. And the article was included in Fuel in 2020.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

In this study, different crystal size hierarchical nano-HZSM5 single crystals were hydrothermally synthesized by using a mixture with the molar composition of 3TPAOH:0.5Na₂O:0.5Al₂O₃:25SiO₂:xH₂O. Based upon the value of x, the synthesized nano-HZSM5 were designated as HZSM5-375, HZSM5-450 and HZSM5-750. These were characterized by XRD, TEM, EDS, NH₃-TPD, and N₂ adsorption/desorption isotherms. The synthesized zeolites exhibited large total surface area and mesopore volume than com. HZSM5-P38. These zeolites were employed for upgrading of Kraft lignin derived liquefaction bio-oil in a batch reactor at 300°C in supercritical ethanol. The chem. compositions of the upgraded bio-oil samples were determined by GC-MS and CHNS elemental anal. Among all the zeolites used in this research, HZSM5-375 was found to be the best catalyst for bio-oil upgrading due to its small crystal size and significantly large very-strong acid site content. Upon bio-oil upgrading, the HHV value of the stock bio-oil increased from 27.03 MJ/Kg to 30.85 MJ/Kg over HZSM5-375 zeolite. Lastly, the spent catalysts were rejuvenated and characterized by solid-state ²⁷Al/²⁹Si MAS-NMR and XRD techniques. The catalytic performance of rejuvenated HZSM5-375 zeolite was found to decrease due to the loss of Al atoms from the zeolite framework. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Particulate and gaseous emissions from charcoal combustion in barbecue grills was written by Vicente, E. D.;Vicente, A.;Evtyugina, M.;Carvalho, R.;Tarelho, L. A. C.;Oduber, F. I.;Alves, C.. And the article was included in Fuel Processing Technology in 2018.Product Details of 2380-78-1 The following contents are mentioned in the article:

The use of charcoal for cooking and heating can be a major source of air pollution and lead to a wide range of health outcomes. The aim of this study was to exptl. quantify and characterize the gaseous and particulate matter (PM_2.5) emissions from charcoal combustion in a typical brick barbecue grill. The gaseous emission factors were 219±44.8gkg^-1 for carbon monoxide (CO), 3.01±0.698gkg^-1 for nitrogen oxides (NO_x expressed as NO₂), and 4.33±1.53gCkg^-1 for total organic carbon (TOC). Particle emissions (7.38±0.353gkg^-1 of dry charcoal burned) were of the same order of magnitude as those from traditional residential wood burning appliances. About 50% of the PM_2.5 emitted had a carbonaceous nature while water soluble ions accounted, on average, for 17% of the particulate mass. Alkanes (C₁₁-C₁₆ and C₂₃), hopanes, steranes and alkyl-PAHs accounted for small mass fractions of PM_2.5. Phenolic compounds and saccharides represented the major particle-bond organic constituents. The high proportion of either resin acids or syringyl and vanillyl compounds is consistent with emissions from charred coniferous wood. The ratios between anhydrosugars for charcoal are much lower than the values reported for lignite combustion, but overlap those from other biomass burning sources. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Product Details of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Product Details of 2380-78-1

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Evaluation of bioremediation and detoxification potentiality for papermaking black liquor by a new isolated thermophilic and alkali-tolerant Serratia sp. AXJ-M was written by An, Xuejiao;Zhong, Bin;Chen, Guotao;An, Weijuan;Xia, Xiang;Li, Hanguang;Lai, Fenju;Zhang, Qinghua. And the article was included in Journal of Hazardous Materials in 2021.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

There is a great need for efficiently treating papermaking black liquor because it can seriously pollute both soil and water ecosystems. In this study, the Plackett-Burman (PB) exptl. design combined with response surface methodol. (RSM) was used for improving the biodegradation efficiency of lignin by a new isolated thermophilic and alkali-tolerant strain Serratia sp. AXJ-M, and the results showed that a biodegradation efficiency of 70.5% was achieved under optimal culture conditions. The bacterium with ligninolytic activities significantly decreased target the parameters (color 80%, lignin 60%, phenol 95%, BOD 80% and COD 80%). The control and treated samples were analyzed by gas chromatog.-mass spectrometer (GC-MS), which showed that the concentrations of a majority of low-mol.-weight compounds were decreased after biol. treatment. Furthermore, toxicol., genotoxicity and phytotoxicity studies have supported the detoxification by the bacterium of black liquor. Finally, the genome sequence of the thermophilic, alkali-tolerant and lignin-degrading bacterium AXJ-M was completed, and the genetic basis of the thermophilic and alkali-resistant properties of AXJ-M was preliminarily revealed. The dyp-type peroxidase was first reported to have the potential to catalyze lignin degradation structurally. These findings suggest that Serratia sp. AXJ-M may be potentially useful for bioremediation applications for papermaking black liquor. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Reductive Catalytic Depolymerization of Semi-industrial Wood-Based Lignin was written by Lu, Xiaojia;Lagerquist, Lucas;Eranen, Kari;Hemming, Jarl;Eklund, Patrik;Estel, Lionel;Leveneur, Sebastien;Grenman, Henrik. And the article was included in Industrial & Engineering Chemistry Research in 2021.Recommanded Product: 2380-78-1 The following contents are mentioned in the article:

The current work studies the reductive catalytic depolymerization (RCD) of lignin from a novel semi-industrial process. The aim was to obtain aromatic mono-, di-, tri-, and tetramers for further valorization. The substrate and products were characterized by multiple anal. methods, including high pressure size-exclusion chromatog. (HPSEC), gas chromatog.-mass spectrometry, GC-flame ionization detector (FID), GC-FID/thermal conductivity detector (TCD), and NMR. The RCD was studied by exploring the influence of different parameters, such as lignin solubility, reaction time, hydrogen pressure, reaction temperature, pH, type and loading of the catalyst, as well as type and composition of the organic/aqueous solvent. The results show that an elevated temperature, a redox catalyst, and a hydrogen atm. are essential for the depolymerization and stability of the products, while the reaction medium also plays an important role. The highest obtained mono- to tetramers yield was 98% and mono- to dimers yield over 85% in the liquid phase products. The reaction mechanisms influenced the structure of the aliphatic chain in the monomers, but left the phenolic structure along with the methoxy groups largely unaltered. The current work contributes to the development and debottlenecking of the novel and sustainable overall process, which utilizes efficiently all the fractions of wood, in line with the principles of green engineering and chem. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

LC-QTOF-MS identification of major urinary cyclopropylfentanyl metabolites using synthesized standards was written by Vikingsson, Svante;Rautio, Tobias;Wallgren, Jakob;Strand, Anna;Watanabe, Shimpei;Dahlen, Johan;Wohlfarth, Ariane;Konradsson, Peter;Wu, Xiongyu;Kronstrand, Robert;Green, Henrik. And the article was included in Journal of Analytical Toxicology in 2019.HPLC of Formula: 2380-78-1 The following contents are mentioned in the article:

The aim of this studywas to provide the exact structure of abundant and unique metabolites of cyclopropylfentanyl along with synthesis routes. In this study, metabolites were identified in 13 post-mortem urine samples using liquid chromatog- raphy quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). Samples were analyzed with and without enzymic hydrolysis, and seven potential metabolites were synthesized inhouse to provide the identity of major metabolites. Cyclopropylfentanyl was detected in all samples, and the most abundant metabolite was norcyclo- propylfentanyl (M1) that was detected in 12 out of 13 samples. Reference materials were synthesized (synthesis routes provided) to identify the exact structure of the major metabolites 4-hydroxyphenethyl cyclopropylfentanyl (M8), 3,4-dihydroxyphenethyl cyclopropylfentanyl (M5) and 4-hydroxy-3-methoxyphenethyl cyclopropylfentanyl (M9). These metabolites are suitable urinary markers of cyclopropylfentanyl intake as they are unique and detected in a majority of hydrolyzed urine samples. Minor metabolites included two quinone metabolites (M6 and M7), not previously reported for fentanyl analogs. Interestingly, with the exception of norcyclopropylfentanyl (M1), the metabolites appeared to be between 40% and 90% conjugated in urine. In total, 11 metabolites of cyclo- propylfentanyl were identified, including most metabolites previously reported after hepatocyte incubation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1HPLC of Formula: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 2380-78-1

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Preparation of biomass-based gas separation membranes from biochar residue obtained by depolymerization of lignin with ZSM-5 to promote a circular bioeconomy was written by He, Dongpo;Xu, Jingyu;Yang, Yingying;Zhu, Hongwei;Yu, Mengtian;Li, Shengnan;Xu, Shuangping;Zhou, Jinghui;Wang, Xing. And the article was included in International Journal of Biological Macromolecules in 2022.Synthetic Route of C9H12O3 The following contents are mentioned in the article:

Reuse of biochar residues after lignin degradation will not only save costs but also reduce the pollution, protect and improve the environment. In this study, biochar residue (BR) after peanut shell lignin selective depolymerization on ZSM-5 were recycled, and characterized by SEM, surface area and pore size distribution analyzers, TGA. Subsequently, a series of hybrid matrix membranes were prepared using Et cellulose as the matrix and biochar residue after depolymerization under different reaction conditions as the filler.separation performance of BR/EC membranes for CO₂/CH₄ mixed gas and CO₂/N₂ mixed gas was measured. The results showed that the gas separation membranes prepared with biochar residue (3 h, 300°C) as filler had good gas separation characteristics. The resulting mixed-matrix membrane exhibited a permeability of 66.00 Barrer for CO₂ and selectivities of 9.97 for CO₂/CH₄. Meanwhile, the resulting mixed-matrix membrane exhibited a permeability of 79.53 Barrer for CO₂ and selectivities of 20.01 for CO₂/N₂. Both exceed the upper limit of known pure EC membranes. Therefore, the use of biochar residue after ZSM-5 depolymerization as a filler for gas separation membranes is a feasible way. Furthermore, the membrane is well stabilized, proving its good potential for industrial applications. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Synthetic Route of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Potential of Thai herbal extracts on lung cancer treatment by inducing apoptosis and synergizing chemotherapy was written by Poofery, Juthathip;Khaw-on, Patompong;Subhawa, Subhawat;Sripanidkulchai, Bungorn;Tantraworasin, Apichat;Saeteng, Somcharoen;Siwachat, Sopon;Lertprasertsuke, Nirush;Banjerdpongchai, Ratana. And the article was included in Molecules in 2020.Name: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

The incidence of lung cancer has increased while the mortality rate has continued to remain high. Effective treatment of this disease is the key to survival. Therefore, this study is a necessity in continuing research into new effective treatments. In this study we determined the effects of three different Thai herbs on lung cancer. Bridelia ovata, Croton oblongifolius, and Erythrophleum succirubrum were extracted by Et acetate and 50% ethanol. The cytotoxicity was tested with A549 lung cancer cell line. We found four effective extracts that exhibited toxic effects on A549 cells. These extracts included Et acetate extracts of B. ovata (BEA), C. oblongifolius (CEA), and E. succirubrum (EEA), and an ethanolic extract of E. succirubrum (EE). Moreover, these effective extracts were tested in combination with chemotherapeutic drugs. An effective synergism of these treatments was found specifically through a combination of BEA with methotrexate, EE with methotrexate, and EE with etoposide. Apoptotic cell death was induced in A549 cells by these effective extracts via the mitochondria-mediated pathway. Addnl., we established primary lung cancer and normal epithelial cells from lung tissue of lung cancer patients. The cytotoxicity results showed that EE had significant potential to be used for lung cancer treatment. In conclusion, the four effective extracts possessed anticancer effects on lung cancer. The most effective extract was found to be E. succirubrum (EE). This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Name: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalytic depolymerization of alkaline lignin to value-added phenolic-based compounds over Ni/CeO₂-ZrO₂ catalyst synthesized with a one-step chemical reduction of Ni species using NaBH₄ as the reducing agent was written by Totong, Sansanee;Daorattanachai, Pornlada;Laosiripojana, Navadol;Idem, Raphael. And the article was included in Fuel Processing Technology in 2020.Recommanded Product: 2380-78-1 The following contents are mentioned in the article:

Alk. lignin obtained from paper manufacturing is a potential feedstock for upgrading to produce value-added chems. This study demonstrates the efficiencies of synthesized Ni supported CeO₂-ZrO₂ catalysts to convert this low-cost alk. lignin into value-added phenolic-based chems. for further com. applications. Lignin depolymerization was performed under mild reaction conditions, namely, reaction temperature of 200-300°C, and reaction time of 1-5 h. Three different catalyst preparation methods (simple wet-impregnation, wet-impregnation assisted reduction in H₂ atmosphere and one-step chem. reduction) were investigated and used to evaluate possible correlations between the active Ni phase and catalytic performance in lignin depolymerization The active Ni phase was successfully formed by one-step chem. reduction method which showed a significant improvement on product yield, especially lignin oil. The best result obtained in lignin depolymerization was by using 10%Ni/CeO₂-ZrO₂-red catalyst which resulted in producing a high yield of lignin oil (46.8%) from lignin feedstock under mild condition of 250°C. The major phenolic compounds in lignin oil were: guaiacol, methyl-guaiacol, ethyl-guaiacol, vanillin, acetovanillone, and homovanillic acid. Furthermore, the reaction temperature affected the product yield and product distribution resulting in higher diversity of phenolic compounds in lignin oil. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 2380-78-1

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Quantitative analysis of aqueous phases of bio-oils resulting from pyrolysis of different biomasses by two-dimensional comprehensive liquid chromatography was written by Lazzari, Eliane;Arena, Katia;Caramao, Elina B.;Herrero, Miguel. And the article was included in Journal of Chromatography A in 2019.Application of 2380-78-1 The following contents are mentioned in the article:

Agrifood byproducts are perfect candidates to be further processed under the concept of circular economy, in order to produce their valorization. Although significant amounts of food-related wastes that are discarded are produced worldwide, these might still be rich in valuable compounds A strategy to further valorize agrifood-related byproducts is based on pyrolysis processes. The result of this process is a liquid product termed bio-oil which is composed of an organic phase and an aqueous phase. This bio-oil is rich on a variety of components and its anal. implies several challenges. In this work, quant. online comprehensive two-dimensional liquid chromatog. (LC × LC) is proposed for the first time to characterize several aqueous phases of different bio-oils. Rice husk, peanut shell, spent coffee grounds, peach core and Eucalyptus sawdust biomasses were analyzed. The developed quant. LC × LC method presented very good linearity, precision, reproducibility, recovery and LODs and LOQs as low as 0.05 μg mL^-1 and 0.16 μg mL^-1, resp. As much as 28 components were simultaneously separated and quantified in those samples. Our results found that the composition of these bio-oils was different but strongly related to the agrifood byproduct submitted to pyrolysis. The developed methodol. is foreseen as a valuable tool for the quant. study of other bio-oils, considering the great complexity and high dimensionality of these samples. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem