Category: 2398-37-0

In 2019,Applied Organometallic Chemistry included an article by Moradi, Parisa; Hajjami, Maryam; Valizadeh-Kakhki, Fatemeh. Name: 1-Bromo-3-methoxybenzene. The article was titled 《Biochar as heterogeneous support for immobilization of Pd as efficient and reusable biocatalyst in C-C coupling reactions》. The information in the text is summarized as follows:

Biochar nanoparticles (BNPs) was modified with 3-choloropropyltrimtoxysilane and further 2-(thiophen-2-yl)-1H-benzo[d]imidazole was anchored on its surface. Then, palladium nanoparticles were fabricated on the surface of the modified BNPs and further the catalytic application was studied as recyclable biocatalyst in carbon-carbon coupling reactions such as Suzuki-Miyaura and Heck-Mizoroki cross-coupling reactions to afford biaryl compounds R-R1 [R = Ph, 3,4-FC6H3; R1 = Ph, 4-BrC6H4, 2-naphthyl, etc.] and phenyl-acrylates R2CH=CHR3 [R2 = CO2Bu, CO2Me, CN; R3 = Ph, 2-MeC6H4, 4-MeOC6H4, etc.] was reported. The structure of the catalyst was characterized using SEM, transmission electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric anal., X-ray diffraction and at. absorption spectroscopy. In the experiment, the researchers used many compounds, for example, 1-Bromo-3-methoxybenzene(cas: 2398-37-0Name: 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Name: 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Khan, Danish; Parveen, Iram; Shaily; Sharma, Saurabh published an article in Asian Journal of Organic Chemistry. The title of the article was 《Design, Synthesis and Characterization of Aurone Based α,β-unsaturated Carbonyl-Amino Ligands and their Application in Microwave Assisted Suzuki, Heck and Buchwald Reactions》.Application In Synthesis of 1-Bromo-3-methoxybenzene The author mentioned the following in the article:

A new series of phosphine-free aurone-based α,β-unsaturated carbonyl-amino bidentate ligands I [R1 = 2-furanyl, Ph, 3-4-dimethoxyphenyl, etc.; R2 = Ph, 3-nitrophenyl, 1-naphthyl, etc.] were synthesized and characterized via different anal. techniques such as IR, 1H-NMR, 13C-NMR and mass spectrometry. Moreover, the structure of ligand I [R1 = 2-furanyl; R2 = 2-nitrophenyl] was also characterized by single-crystal X-ray diffraction. The synthesized ligands I with the PdCl2 salt showed excellent catalytic activity in the Suzuki-Miyaura, Mizoroki-Heck and Buchwald-Hartwig reactions. A broad range of substrates including heterocycles, chalcones and sterically hindered coupling partners were well tolerated in the developed protocol. Addnl., the metal complex formed in the catalytic cycle was characterized by 1H-NMR spectroscopy and mass spectrometry. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0Application In Synthesis of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Application In Synthesis of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC of Formula: 2398-37-0In 2022 ,《Synthesis of selenopyrano[2,3-b]indol-4(9H)-ones and their C H arylation》 was published in Journal of Heterocyclic Chemistry. The article was written by Woo-Jin, Choi; Jalani, Hitesh B.; Jeong, Jin-Hyun. The article contains the following contents:

Herein, authors disclose the synthesis of selenopyrano[2,3-b]indol-4(9H)-ones and their aryl derivatives using seleno-pyran ring formation via an in situ-generated selenide reacting directly with α-halo-β-ynones of substituted indoles providing selenopyrano[2,3-b]indol-4(9H)-ones. Subsequent direct CH arylation of the these compounds by palladium-catalyzed Heck reaction enables the incorporation of aryl substituents on the selenopyrano[2,3-b]indol-4(9H)-ones scaffolds with moderate yields. This new chemo-type incorporating an indole ring may be useful for the biol. screenings. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0HPLC of Formula: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.HPLC of Formula: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Basson, Ashley J.; Halcovitch, Nathan R.; McLaughlin, Mark G. published an article in Chemistry – A European Journal. The title of the article was 《Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization》.Synthetic Route of C7H7BrO The author mentioned the following in the article:

A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs. The experimental process involved the reaction of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Synthetic Route of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Synthetic Route of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xu, Hang; Yan, Zhong-zuo; Guo, Meng-bi; An, Ran; Wang, Xin; Zhang, Rui; Mou, Yan-hua; Hou, Zhuang; Guo, Chun published their research in European Journal of Medicinal Chemistry in 2021. The article was titled 《Lead optimization generates selenium-containing miconazole CYP51 inhibitors with improved pharmacological profile for the treatment of fungal infections》.Application In Synthesis of 1-Bromo-3-methoxybenzene The article contains the following contents:

A series of selenium-containing miconazoles. compounds I, II [R = H, 3-F, 2-Me, etc. ; X= F, Cl], III [R = H, 3-F, 2-Me, etc.; X= F, C] were identified as potent antifungal drugs in our previous study. Representative compound I (MIC = 0.01μg/mL against C.alb. 5314) proved efficacious in inhibiting the growth of fungal pathogens. However, further study showed lead compound I exhibited potential hemolysis, significant cytotoxic effect and unfavorable metabolic stability and was therefore modified to overcome these drawbacks. In this article, the further optimization of selenium-containing miconazole derivatives resulted in the discovery of similarly potent compound II [R = 4-F ; X= F] (MIC = 0.02μg/mL against C.alb. 5314), exhibiting a superior pharmacol. profile with decreased rate of metabolism, cytotoxic effect and hemolysis. Furthermore, compound II [R = 4-F ; X= F] showed fungicidal activity against Candida albicans and significant effects on the treatment of resistant Candida albicans infections. Meanwhile, compound II [R = 4-F ; X= F] not only could reduce the ergosterol biosynthesis pathway by inhibiting CYP51, but also inhibited biofilm formation. More importantly, compound II [R = 4-F ; X= F] also shows promising in vivo efficacy after i.p. injection and the PK study of compound II [R = 4-F ; X= F] was evaluated. In addition, mol. docking studies provide a model for the interaction between the compound II [R = 4-F ; X= F] and the CYP51 protein. Overall, it was believed that these selenium-containing miconazole compounds can be further developed for the potential treatment of fungal infections. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Application In Synthesis of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Application In Synthesis of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Product Details of 2398-37-0In 2020 ,《Engineering the charge-transfer state to facilitate spin-orbit charge transfer intersystem crossing in spirobis[anthracene]diones》 was published in Angewandte Chemie, International Edition. The article was written by Lv, Meng; Yu, Yang; Sandoval-Salinas, Maria E.; Xu, Jianhua; Lei, Zuhai; Casanova, David; Yang, Youjun; Chen, Jinquan. The article contains the following contents:

Spiro conjugation has been proposed to dictate the efficiency of charge transfer, which could directly affect the spin-orbit charge transfer intersystem crossing (SOCT-ISC) process. However, this process has yet to be exemplified. Herein, we prepared three spirobis[anthracene]diones, in which two benzophenone moieties are locked in close proximity and differentially functionalized to fine-tune the charge transfer state. Its feasibility for SOCT-ISC was theor. predicted, then exptl. evaluated. Through fine-tuning the spiro conjugation coupling and varying the solvent dielec. constants, ISC rate constants were engineered to vary in a dynamic range of three orders of magnitude, from 7.8×108 s-1 to 1.0×1011 s-1, which is the highest ISC rate reported for SOCT-ISC system to our knowledge. Our findings substantiate the key factors for effective SOCT-ISC and offer a new avenue for the rational design of heavy atom free triplet sensitizers. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0Product Details of 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Product Details of 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Cyr, Patrick; Joseph-Valcin, Eve-Marline; Boissarie, Patrick; Simoneau, Bruno; Marinier, Anne published an article in European Journal of Organic Chemistry. The title of the article was 《Copper-Catalyzed N1 Coupling of 3-Aminoindazoles and Related Aminoazoles with Aryl Bromides》.Synthetic Route of C7H7BrO The author mentioned the following in the article:

The N1-selective arylation of 3-aminoindazoles using copper catalysis was reported. The reaction used readily accessible aryl bromides as coupling partners, including those from heterocycles and allowed easy access to a broad variety of substituted 3-aminoindazoles. The methodol. was also examined on other aminoazoles of interest for the pharmaceutical industry. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0Synthetic Route of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Synthetic Route of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Cartagenova, Daniele; Bachmann, Stephan; Puntener, Kurt; Scalone, Michelangelo; Newton, Mark A.; Peixoto Esteves, Fabio A.; Rohrbach, Thomas; Zimmermann, Patrik P.; van Bokhoven, Jeroen A.; Ranocchiari, Marco published an article in Catalysis Science & Technology. The title of the article was 《Highly selective Suzuki reaction catalyzed by a molecular Pd-P-MOF catalyst under mild conditions: role of ligands and palladium speciation》.Synthetic Route of C7H7BrO The author mentioned the following in the article:

A molecularly-defined heterogeneous palladium catalyst based on a phosphine-metal-organic framework (P-MOF) ligand system was reported. This catalyst performed Suzuki reactions of aryl bromides and Ph boronic acid to afford biaryls R-R1 [R = Ph; R1 = 3-MeC6H4, 3-OMeC6H4, 3-pyridyl, etc.] in exceptionally mild conditions while displayed a unique selectivity, higher than that achieved using Pd(PPh3)4, a standard homogeneous catalyst. The new palladium P-MOF catalyst was active for a wide range of substrates. Determination of the palladium speciation showed that molecularly-defined palladium-phosphine sites catalyzed the Suzuki cross-coupling with very high selectivity, and that, when formed, palladium nanoparticles promoted hydrodehalogenation. The fraction of molecularly defined palladium was maximized by having excess of phosphine ligand in the system. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Synthetic Route of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Synthetic Route of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xavier, Tania; Pichon, Christophe; Presset, Marc; Le Gall, Erwan; Condon, Sylvie published an article in 2021. The article was titled 《Efficient Preparation of Methyl 2-Oxo-3-aryl (heteroaryl)-2H-pyran-5-carboxylate via Pd-Catalyzed Negishi Coupling》, and you may find the article in European Journal of Organic Chemistry.Application In Synthesis of 1-Bromo-3-methoxybenzene The information in the text is summarized as follows:

Me 3-bromocoumalate, readily obtained from Me 2-pyrone-5-carboxylate (Me coumalate), is easily substituted by cross-coupling reactions with arylzinc reagents ArZnBr (R = Ph, 3-acetylphenyl, thiophen-2-yl, etc.) under palladium catalysis, leading to Me 2-oxo-3-aryl (heteroaryl)-2H-pyran-5-carboxylates I. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Application In Synthesis of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Application In Synthesis of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hu, Zhiyong; Wei, Xiao-Jing; Handelmann, Jens; Seitz, Ann-Katrin; Rodstein, Ilja; Gessner, Viktoria H.; Goossen, Lukas J. published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Coupling of Reformatsky reagents with aryl chlorides enabled by ylide-functionalized phosphine ligands》.Computed Properties of C7H7BrO The article contains the following contents:

The coupling of aryl chlorides with Reformatsky reagents is a desirable strategy for the construction of α-aryl esters but has so far been substantially limited in the substrate scope due to many challenges posed by various possible side reactions. This limitation has now been overcome by the tailoring of ylide-functionalized phosphines to fit the requirements of Negishi couplings. Record-setting activities were achieved in palladium-catalyzed arylations of organozinc reagents with aryl electrophiles using a cyclohexyl-YPhos ligand bearing an ortho-tolyl-substituent in the backbone. This highly electron-rich, bulky ligand enables the use of aryl chlorides in room temperature couplings of Reformatsky reagents. The reaction scope covers diversely functionalized arylacetic and arylpropionic acid derivatives Aryl bromides and chlorides can be converted selectively over triflate electrophiles, which permits consecutive coupling strategies. In addition to this study using 1-Bromo-3-methoxybenzene, there are many other studies that have used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Computed Properties of C7H7BrO) was used in this study.

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Computed Properties of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem