Category: ethers-buliding-blocks

Jin, Youngeup published the artcileSynthesis and electroluminescent properties of copolymers based on PPV with fluoro groups in vinylene units, Application In Synthesis of 146370-51-6, the publication is Polymer (2007), 48(6), 1541-1549, database is CAplus.

Electroluminescent copolymers with fluoro groups on vinylene units, poly(2-ethylhexyloxy-5-methoxy-p-phenylenevinylene-co-2-dimethyloctylsilyl-p-phenylenedifluorovinylene) (MEH-PPV-co-DMOS-PPDFV) and poly(2-dimethyloctylsilyl-p-phenylenevinylene-co-2-dimethyloctylsilyl-p-phenylenedifluorovinylene) (DMOS-PPV-co-DMOS-PPDFV), were synthesized by the Gilch polymerization route. The fluoro groups were introduced on vinylene units to increase the electron affinity of the copolymers. In both copolymers, the band gap increased with higher ratio of DMOS-PPDFV. As compared to the photoluminescence (PL) spectra in solution, the PL spectra in solid state and EL spectra of both copolymers showed red shift and broad peaks caused by aggregation. The LEDs fabricated using MEH-PPV-co-DMOS-PPDFVs emit light with maximum at around 538-577 nm. By adjusting the feed ratio of DMOS-PPDFV in the copolymer, the emission colors were tuned from orange yellow to green. The DMOS-PPV-co-DMOS-PPDFV showed maximum electroluminescence (EL) peaks at about 514-543 nm. The DMOS-PPV-co-DMOS-PPDFV with 1:9 feed ratio showed the highest luminescence efficiency of 1.31 lm/W.

Polymer published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, Application In Synthesis of 146370-51-6.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

De Joarder, Dripta published the artcileEnantioselective synthesis of a potential 1,5-syn-polyol C1-C24 subunit of (-)-caylobolide A, Safety of (+)-B-Methoxydiisopinocampheylborane, the publication is Tetrahedron Letters (2013), 54(43), 5826-5829, database is CAplus.

The synthesis of a protected possible 1,5-syn-polyol C(1)-C(24) subunit, I (TES = Et₃Si), resident in (-)-caylobolide A was accomplished. The key reaction sequence was a repetitive protocol for the construction of the syn-1,5-diol segment by Ru-catalyzed cross-metathesis and B-mediated allylation reactions.

Tetrahedron Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Safety of (+)-B-Methoxydiisopinocampheylborane.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bartling, Christian R. O. published the artcileTargeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation, SDS of cas: 77128-73-5, the publication is Journal of the American Chemical Society (2021), 143(2), 891-901, database is CAplus and MEDLINE.

There is an urgent need for novel therapeutic approaches to treat Alzheimer’s disease (AD) with the ability to both alleviate the clin. symptoms and halt the progression of the disease. AD is characterized by the accumulation of amyloid-β (Aβ) peptides which are generated through the sequential proteolytic cleavage of the amyloid precursor protein (APP). Previous studies reported that Mint2, a neuronal adaptor protein binding both APP and the γ-secretase complex, affects APP processing and formation of pathogenic Aβ. However, there have been contradicting results concerning whether Mint2 has a facilitative or suppressive effect on Aβ generation. Herein, we deciphered the APP-Mint2 protein-protein interaction (PPI) via extensive probing of both backbone H-bond and side-chain interactions. We also developed a proteolytically stable, high-affinity peptide targeting the APP-Mint2 interaction. We found that both an APP binding-deficient Mint2 variant and a cell-permeable PPI inhibitor significantly reduced Aβ₄₂ levels in a neuronal in vitro model of AD. Together, these findings demonstrate a facilitative role of Mint2 in Aβ formation, and the combination of genetic and pharmacol. approaches suggests that targeting Mint2 is a promising therapeutic strategy to reduce pathogenic Aβ levels.

Journal of the American Chemical Society published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C25H23NO4, SDS of cas: 77128-73-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Diao, Xinyong published the artcileFabricating high temperature stable Mo-Co₉S₈/Al₂O₃ catalyst for selective hydrodeoxygenation of lignin to arenes, Quality Control of 91-16-7, the publication is Applied Catalysis, B: Environmental (2022), 121067, database is CAplus.

Achieving high-temperature stability/duration without compromising the activity remains an arduous task in catalyst design, particularly for MoS₂ materials. Herein, a robust catalyst with Mo doped Co₉S₈ nanoparticles anchored on Al₂O₃ matrix is fabricated, which could selectively convert lignin to arenes with high hydrodeoxygenation activity, selectivity and particularly excellent stability. In the hydrodeoxygenation of di-Ph ether, this catalyst afforded 99.8% conversion and 91.0% yield of benzene at 265°C for at least 10 reaction runs. The resultant Mo-Co₉S₈ structure with chem. connection by covalent bonds of Mo-S-Co type on the Co₉S₈ surface demonstrates strong ability in the adsorption and activation of oxygen-containing substrates, which enables the effective C-O cleavage while avoids undesirable hydrogenation of benzene ring. The superior stability and water-resistance at elevated temperature was attributed to the anchoring effect of Al₂O₃ matrix and “protection” of surface-rich Co₉S₈ species to the active Mo-Co₉S₈ center. This strategy provides new sights for the rational design of efficient and stable sulfide catalysts toward the applications in demanding high-temperature reactions.

Applied Catalysis, B: Environmental published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Quality Control of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Jia, Zhichao published the artcileHighly Selective Hydrodeoxygenation of Lignin to Naphthenes over Three-Dimensional Flower-like Ni₂P Derived from Hydrotalcite, Category: ethers-buliding-blocks, the publication is ACS Catalysis (2022), 12(2), 1338-1356, database is CAplus.

A strategy for low-temperature synthesis of hydrotalcite-based nickel phosphide catalysts (Ni₂P-Al₂O₃) with flower-like porous structures was proposed. The in situ reduction of red phosphorus at 500°C enables Ni₂P catalysts with small particle size and abundant active and acidic sites, which facilitate the activation of substrates and H₂. In the hydrodeoxygenation of guaiacol, a 100% conversion and 94.5% yield of cyclohexane were obtained over the Ni₂P-Al₂O₃ catalyst under 5 MPa H₂ at 250°C for 3 h. Other lignin-derived phenolic compounds could also afford the corresponding alkanes with yields higher than 85%. Moreover, Ni₂P-Al₂O₃ exhibited high hydrodeoxygenation activity in the deconstruction of more complex wood structures, including lignin oil and real lignin. Among the two different types of Ni sites of Ni(1) and Ni(2) in Ni₂P, d. functional theory (DFT) calculations showed that the Ni(2) site, highly exposed on the Ni₂P-Al₂O₃ surface, possesses a stronger ability to break C-OH bonds during the hydrodeoxygenation of guaiacol in comparison with the Ni(1) site.

ACS Catalysis published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Xu, Wenshuai published the artcileOne-pot synthesis of dimethyl carbonate over basic zeolite catalysts, Application In Synthesis of 1589-47-5, the publication is Modern Research in Catalysis (2013), 2(2A), 22-27, database is CAplus.

One-pot synthesis of di-Me carbonate (DMC) from methanol, propylene oxide (PO) and carbon dioxide has been investigated using the basic zeolites as catalysts. Among the zeolites studied, Beta showed the best catalytic performance for DMC production That the desilication of zeolite structure resulted in a hierarchical porosity of Beta, leading to more amount of KOH can be loaded on the surface of zeolite and therefore enhancing the base strength of the catalyst was proposed to be the reason for improved catalytic performance.

Modern Research in Catalysis published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C17H14F3N3O2S, Application In Synthesis of 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Guo, Ying published the artcileA ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system, Category: ethers-buliding-blocks, the publication is Research on Chemical Intermediates (2015), 41(11), 8651-8664, database is CAplus.

A ligand-free, powerful, and practical method for mono and polymethoxylation of unactivated aryl bromides has been developed; CuCl was used as catalyst, HCOOMe as cocatalyst, and methanolic MeONa as both nucleophile and solvent. This eco-friendly procedure is characterized by operational simplicity, inexpensive substrates (unactivated mono to polybromoarenes), full conversion, and direct recovery of pure MeOH.

Research on Chemical Intermediates published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bolton, P. D. published the artcileHydrolysis of amides. III. Dilute acid hydrolysis of amides of the type RCH2CONH2, Formula: C3H7NO2, the publication is Australian Journal of Chemistry (1969), 22(3), 527-32, database is CAplus.

Rate constants over a range of temperature, enthalpies of activation, and entropies of activation are reported for the dilute acid hydrolysis of n-valeramide, isovaleramide, 3,3-dimethylbutanamide, phenylacetamide, cyclohexylacetamide, methoxyacetamide, bromoacetamide, and chloroacetamide. The rate constants of the first six amides together with those of two other alkyl-substituted acetamides determined earlier are almost perfectly correlated by the Taft linear steric energy relation. The enthalpies of activation, also, show a linear dependence on the steric parameter, Es. The results obtained for the halo amides indicate that the acid hydrolysis of amides may show a slight sensitivity to polar effects.

Australian Journal of Chemistry published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Formula: C3H7NO2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bolton, Peter D. published the artcileHydrolysis of amides. V. Alkaline hydrolysis of alkyl-substituted amides, COA of Formula: C3H7NO2, the publication is Australian Journal of Chemistry (1971), 24(5), 969-74, database is CAplus.

Enthalpies and entropies of activation were derived from rate constants measured over a range of temperature for the alk. hydrolysis of acetamide, propionamide, butyramide, n-valeramide, isovaleramide, phenylacetamide, cyclohexylacetamide, methoxyacetamide, cyclohex-anecarboxamide, cyclopentane carboxamide, α-methylbutyramide, isobutyramide, and trimethylacetamide. These results are discussed in terms of their correlation by Taft-type equations which were extended to incorporate a factor based upon the α-hydrogen bond concept of hyperconjugative stabilization. The rate constants of these 13 amides under these conditions appear to be governed by a combination of polar, steric, and hyperconjugative factors.

Australian Journal of Chemistry published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, COA of Formula: C3H7NO2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Brown, Herbert C. published the artcileChiral synthesis via organoboranes. 13. A highly diastereoselective and enantioselective addition of [(Z)-γ-alkoxyallyl]diisopinocampheylboranes to aldehydes, COA of Formula: C21H37BO, the publication is Journal of the American Chemical Society (1988), 110(5), 1535-8, database is CAplus.

Isomerically pure [(Z)-γ-methoxyallyl]diisopinocampheylboranes, I, prepared from (+)-α-pinene and II, have been prepared from B-methoxydiisopinocampheylborane and lithiated allyl Me ether. These enantiomeric [(Z)-γ-methoxyallyl]diisopinocampheylboranes retain their stereochem. identity under the reaction conditions. They have been successfully condensed with various aldehydes, such as acetaldehyde, propionaldehyde, 2-methylpropionaldehyde, and benzaldehyde in a regioselective and stereoselective manner to yield the corresponding threo-β-methoxyhomoallyl alcs. in â‰?9% diastereoselectivities and â‰?5% enantioselectivities. Similarly, [(Z)-γ-[(methoxymethyl)oxy]allyl]diisopinocampheylborane was prepared and was utilized for the preparation of threo-1,2-diol.

Journal of the American Chemical Society published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, COA of Formula: C21H37BO.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem