Category: ethers-buliding-blocks

Xiong, Ying published the artcileEnantioselective Total Synthesis of (-)-Hamigeran F and Its Rearrangement Product, Application In Synthesis of 725251-81-0, the publication is Organic Letters (2022), 24(28), 5161-5165, database is CAplus and MEDLINE.

Herein, we report the first enantioselective total synthesis of the highly complex hamigeran diterpenoid (-)-hamigeran F and its rearrangement product. The synthetic strategy features key steps of asym. hydrogenation, Horner-Wadsworth-Emmons olefination, and intramol. Friedel-Crafts acylation to construct the [6,6,5]-tricyclic skeleton bearing three consecutive stereocenters, a sequence of steps involving Rosenmund reduction, Wittig reaction, dihydroxylation to assemble the α-acetoxy ketone group, and an intramol. aldol reaction to build the tetracyclic core structure.

Organic Letters published new progress about 725251-81-0. 725251-81-0 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Methoxy-5-methylphenyl)boronic acid, and the molecular formula is C18H23N3O4S, Application In Synthesis of 725251-81-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhou, Yu-Xiao published the artcileMIL-101-SO₃H: A Highly Efficient Bronsted Acid Catalyst for Heterogeneous Alcoholysis of Epoxides under Ambient Conditions, SDS of cas: 1589-47-5, the publication is Chemistry – A European Journal (2014), 20(46), 14976-14980, database is CAplus and MEDLINE.

For the first time, a ∼100% sulfonic acid functionalized metal-organic framework (MOF), MIL-101-SO₃H, with giant pores (macroporous material) has been prepared by a hydrothermal process followed by a facile postsynthetic hydrochloric acid (HCl) treatment strategy. The replete readily accessible Lewis acidic and especially Bronsted acidic sites distributed throughout the framework as well as high stability endow the resultant MOF exceptionally high efficiency and recyclability, which surpass all other MOF-based catalysts, for the ring opening of epoxides with alcs. (especially, methanol) as nucleophiles under ambient reaction conditions. The synthesis of the target compound (catalyst) was achieved using chromium oxide (CrO₃) with 2-sulfo-1,4-benzenedicarboxylic acid sodium salt [i.e., 2-sulfoterephthalic acid monosodium salt] as reactants. Oxirane starting materials included 2-(phenyl)oxirane, 2-(methyl)oxirane, 2-(chloromethyl)oxirane, 2-oxiranemethanol and 2,2-dimethyl(epoxide). Regioselective ring-opening reaction products with alcs. included β-(methoxy)benzeneethanol, β-(ethoxy)benzeneethanol, β-(propoxy)benzeneethanol, β-(1,1-dimethylethoxy)benzeneethanol, 2-methoxy-1-propanol, 2-ethoxy-1-propanol, 2-propoxy-1-propanol and related compounds (primary alcs.). Secondary alcs. were also formed.

Chemistry – A European Journal published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C19H14O2, SDS of cas: 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yao, Juanjuan published the artcileNew insight into the regulation mechanism of visible light in naproxen degradation via activation of peroxymonosulfate by MOF derived BiFeO₃, Application of 2-Methoxynaphthalene, the publication is Journal of Hazardous Materials (2022), 128513, database is CAplus and MEDLINE.

BiFeO₃ (BFO) nanocage prepared by metal-organic-framework derivatization (MOF-d) was adopted as activator to first investigate the effect mechanism of visible-light on naproxen-degradation via peroxymonosulfate (PMS) activation. MOF-d BFO expressed more excellent PMS activation ability than hydrothermal-synthetic BFO, due to highly ordered mesopores. A 3.0 times higher pseudo-first-order degradation rate constant was achieved after visible-light introduced. The quenching experiments indicated that the contribution of ROS in naproxen degradation followed the order of SO•^–₄>¹O₂ ≈ •OH in MOF-d BFO/PMS/dark system, while changed into h⁺>¹O₂ > >O•-app2SO•^–₄> •OH after visible-light introduced. EPR tests first revealed that visible-light promoted ¹O₂ yield (non-radical pathway) but suppressed •OH and SO•^–₄ generation (free-radical pathways). N2-purging experiments further proved that ¹O₂ primarily originates from the reaction between h⁺ and PMS, equivalently to that between O₂ and e^–-h⁺ in MOF-d BFO/PMS/vis system. Under visible-light, PMS activation via Fe (III) might be hindered by e- filling on Fe 3d orbital and anion PMS preferred to approach h⁺ rather than e^–, resulting in the decrease of •OH and SO•^–₄ yields. Moreover, PMS faces competition from adsorbed-O₂ and oxygen-vacancies for e^– capture. The degradation-pathways for naproxen in dark and under visible light were both proposed in MOF-d BFO/PMS system.

Journal of Hazardous Materials published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C22H38O2, Application of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Pan, Jiang-Qing published the artcileSynthesis and characterization of fully soluble polyphenylenevinylene, SDS of cas: 146370-51-6, the publication is Chinese Journal of Polymer Science (2000), 18(6), 541-549, database is CAplus.

Fully soluble poly[2-(2-ethylhexyloxy)-5-methoxy-p-phenylenevinylene] was synthesized by the polymerization of 2-(2-ethylhexyloxy)-5-methoxy-1,4-xylylene dibromide with addition of mol. weight modifiers (chain stopper, free radical scavengers) to a polymerization system containing monomer, catalyst, and solvent. The polymers synthesized in this work were characterized by IR, NMR, and UV-visible spectroscopy, and gel-permeation chromatog. Results show that the weight-average mol. weight of the polymer can be controlled by the addition of chain stopper (benzyl bromide) and radical inhibitor (BHT). The polymerization mechanism in the presence of these additives was also discussed. A dual mechanism involving carbene for the polymerization was proposed.

Chinese Journal of Polymer Science published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, SDS of cas: 146370-51-6.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, HPLC of Formula: 91-16-7, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, Recommanded Product: 2-Methoxynaphthalene, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chang, Hson Mou published the artcileStructure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen), HPLC of Formula: 2944-47-0, the publication is Journal of Organic Chemistry (1990), 55(11), 3537-43, database is CAplus.

Eleven new compounds were isolated from the dried root of Salvia miltiorrhiza Bunge “Danshen”, and their structures were elucidated by spectrometric methods. The total syntheses of 2 new compounds namely, 1,2-didehydromiltirone (I) and 4-methylenemiltirone (II) are also reported.

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, HPLC of Formula: 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lui, Yuen Wai published the artcileMethylation with Dimethyl Carbonate/Dimethyl Sulfide Mixtures: An Integrated Process without Addition of Acid/Base and Formation of Residual Salts, COA of Formula: C11H10O, the publication is ChemSusChem (2022), 15(3), e202102538, database is CAplus and MEDLINE.

Di-Me sulfide, a major byproduct of the Kraft pulping process, was used as an inexpensive and sustainable catalyst/co-reagent (Me donor) for various methylations with di-Me carbonate (as both reagent and solvent), which afforded excellent yields of O-methylated phenols and benzoic acids, and mono-C-methylated arylacetonitriles. Furthermore, these products could be isolated using a remarkably straightforward workup and purification procedure, realized by di-Me sulfide’s neutral and distillable nature and the absence of residual salts. The likely mechanisms of these methylations were elucidated using exptl. and theor. methods, which revealed that the key step involves the generation of a highly reactive trimethylsulfonium methylcarbonate intermediate. The phenol methylation process represents a rare example of a Williamson-type reaction that occurs without the addition of a Bronsted base.

ChemSusChem published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, COA of Formula: C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Qingyu published the artcileHypervalent Chalcogenonium…π Bonding Catalysis, Computed Properties of 91-16-7, the publication is Angewandte Chemie, International Edition, database is CAplus and MEDLINE.

A proof-of-concept study of hypervalent chalcogenonium…π bonding catalysis was performed. A new catalytic strategy using 1,2-oxaselenolium salts as chalcogen bond donors and alkenes as chalcogen bond acceptors is described. The feasibility of this concept is demonstrated by the use of trisubstituted selenonium salts in the metal-free catalytic hydrofunctionalization and polymerization of alkenes via unconventional seleniranium ion-like intermediates. The results indicate that counter anions have a significant effect on the catalysis based on hypervalent chalcogenonium…π bonding interactions.

Angewandte Chemie, International Edition published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C7H5Cl2NO, Computed Properties of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Qingyu published the artcileHypervalent Chalcogenonium…π Bonding Catalysis, Synthetic Route of 93-04-9, the publication is Angewandte Chemie, International Edition, database is CAplus and MEDLINE.

A proof-of-concept study of hypervalent chalcogenonium…π bonding catalysis was performed. A new catalytic strategy using 1,2-oxaselenolium salts as chalcogen bond donors and alkenes as chalcogen bond acceptors is described. The feasibility of this concept is demonstrated by the use of trisubstituted selenonium salts in the metal-free catalytic hydrofunctionalization and polymerization of alkenes via unconventional seleniranium ion-like intermediates. The results indicate that counter anions have a significant effect on the catalysis based on hypervalent chalcogenonium…π bonding interactions.

Angewandte Chemie, International Edition published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C9H9BN2O2, Synthetic Route of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem