Category: ethers-buliding-blocks

Zou, Zidan published the artcileCore shell hetero-structured SiO₂@Ni/SiO₂ catalyst for efficient aqueous-phase hydrogenation of bio-derived unsaturated compounds, SDS of cas: 134-96-3, the publication is Fuel (2022), 123694, database is CAplus.

Silica is one of the most referenced materials for the preparation of heterogeneous metal catalysts. However, silica spheres with smooth surfaces have difficulty encapsulating active metals due to their small surface area and the presence of only a handful of silicon hydroxyl groups on the surface. In this work, the silica sphere has been first consciously transformed into a hierarchical SiO₂@silicate structure, and then the core-shell hetero-structured SiO₂@Ni/SiO₂ catalyst can be tactfully obtained by reducing treatment. The core-shell catalyst is composed of a rigid core (SiO2) and a rough shell (Ni NPs highly disperse on nanosheet SiO₂), which are carefully verified by X-ray diffraction (XRD), transmission electron microscope (TEM), field scanning electron microscope (FESEM), H₂-TPR/TPD and XPS. The derived SiO₂@Ni/SiO₂ catalyst can selectively hydrogenate vanillin in the aqueous phase at near-room temperature (40 °C) and low hydrogen pressure (2 MPa H₂), and the conversion of vanillin can be up to 99%. The preparation method of the SiO₂@Ni/SiO₂ catalyst is simple and can be amplified to a large scale at a low price, thus can be adopted to convert bio-derived unsaturated compounds in an economical and eco-friendly way.

Fuel published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C10H16BNO2, SDS of cas: 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Guo, Ge published the artcileCatalytic depolymerization of Kraft lignin towards liquid fuels over bifunctional molybdenum oxide based supported catalyst, Application of 1,2-Dimethoxybenzene, the publication is Fuel (2021), 121599, database is CAplus.

Catalytic depolymerization of Kraft lignin towards valuable liquid fuels and monomeric phenols has been a significant and extremely attractive target, but it remains a great challenge. Herein, we report a catalytic system consisted of bifunctional molybdenum oxide based supported catalyst for catalytic lignin hydroconversion into alkylated benzenes and phenols. In the meantime, the achieved yield of liquid product was 95% and petroleum ether extracted product was 65% at 300°C for 12 h over 20%MoO_x/ZIF-8@ZIF-67 catalyst. The calorific value was increased from 25.66 MJ/ Kg to 34.31 MJ/Kg. The characterization studies show the incorporation of MoOx species leads to the synergy between redox sites and acid sites. The product anal. and catalytic studies demonstrate its synergism to promote catalytic cleavage of C-O linkages via the coupled hydrodeoxygenation and alkylation reaction. The reasonable catalytic mechanism and redox cycle route of catalyst indicate that the cooperative catalytic system paves the way for high-efficiency waste lignin utilization.

Fuel published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Application of 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lei, Tailong published the artcileADMET Evaluation in Drug Discovery. Part 17: Development of Quantitative and Qualitative Prediction Models for Chemical-Induced Respiratory Toxicity, SDS of cas: 16332-06-2, the publication is Molecular Pharmaceutics (2017), 14(7), 2407-2421, database is CAplus and MEDLINE.

As a dangerous end point, respiratory toxicity can cause serious adverse health effects and even death. Meanwhile, it is a common and traditional issue in occupational and environmental protection. Pharmaceutical and chem. industries have a strong urge to develop precise and convenient computational tools to evaluate the respiratory toxicity of compounds as early as possible. Most of the reported theor. models were developed based on the respiratory toxicity data sets with one single symptom, such as respiratory sensitization, and therefore these models may not afford reliable predictions for toxic compounds with other respiratory symptoms, such as pneumonia or rhinitis. Here, based on a diverse data set of mouse i.p. respiratory toxicity characterized by multiple symptoms, a number of quant. and qual. predictions models with high reliability were developed by machine learning approaches. First, a four-tier dimension reduction strategy was employed to find an optimal set of 20 mol. descriptors for model building. Then, six machine learning approaches were used to develop the prediction models, including relevance vector machine (RVM), support vector machine (SVM), regularized random forest (RRF), extreme gradient boosting (XGBoost), naïve Bayes (NB), and linear discriminant anal. (LDA). Among all of the models, the SVM regression model shows the most accurate quant. predictions for the test set (q²_ext = 0.707), and the XGBoost classification model achieves the most accurate qual. predictions for the test set (MCC of 0.644, AUC of 0.893, and global accuracy of 82.62%). The application domains were analyzed, and all of the tested compounds fall within the application domain coverage. We also examined the structural features of the compounds and important fragments with large prediction errors. In conclusion, the SVM regression model and the XGBoost classification model can be employed as accurate prediction tools for respiratory toxicity.

Molecular Pharmaceutics published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, SDS of cas: 16332-06-2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Secinti, Hatice published the artcileTotal Syntheses of Multicaulins via Oxidative Photocyclization of Stilbenes, Application In Synthesis of 2944-47-0, the publication is Journal of Natural Products (2014), 77(9), 2134-2137, database is CAplus and MEDLINE.

The Wittig reaction of 3-isopropyl-4-methoxybenzaldehyde and 2,3-dimethylbenzylphosphonium bromide afforded the corresponding stilbene mixture I. Oxidative photocyclization of stilbene I with iodine facilitated the first total synthesis of 7-isopropyl-6-methoxy-1,2-dimethylphenanthrene, multicaulin (II). The O-demethylation of II with BBr₃ afforded the 7-isopropyl-1,2-dimethylphenanthren-6-ol, O-demethylmulticaulin (III).

Journal of Natural Products published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C16H10O5, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Barry, Conor S. published the artcileStereoselective Synthesis of the Tetrahydropyran Core of Polycavernoside A, SDS of cas: 99438-28-5, the publication is Organic Letters (2005), 7(13), 2683-2686, database is CAplus and MEDLINE.

A concise and stereoselective synthesis of the tetra-substituted tetrahydropyran core of polycavernoside A was achieved in 55% overall yield from 3-benzyloxypropanal. A stereoselective allyl transfer reaction was used in the synthesis of enol ether I followed by a TFA-mediated cyclization to create the three new asym. centers in the tetrahydropyran with complete stereocontrol in a single-pot process.

Organic Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, SDS of cas: 99438-28-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yi, Wen-Bin published the artcileFriedel-Crafts alkylation in fluorous biphasic system catalyzed by rare earth(III) perfluorooctanesulfonate, Recommanded Product: 2-Isopropylanisole, the publication is Yingyong Huaxue (2006), 23(2), 212-214, database is CAplus.

Rare earth (III) perfluorooctanesulfonate salts (catalysts) were prepared and used in Friedel-Crafts alkylation in fluorous biphasic systems. Perfluorohexane, perfluoromethylcyclohexane, perfluorotoluene, perfluorooctane, perfluorooctyl bromide and perfluorodecalin can be used as the fluorous solvent for this kind of reaction. The catalytic activities of other rare earth metal salts with different ligands were tested. The results show that Yb(OSO₂C₈F₁₇)₃ [1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonic acid ytterbium(3+) salt], ,and C₁₀F₁₈ were the best catalyst and fluorous solvent resp. The yield of alkylation of anisole with benzyl alc. was 96% in the presence of Yb(OSO₂C₈F₁₇)₃ and C₁₀F₁₈. By simple phase-separation the fluorous phase containing only catalyst could be re-utilized up to five times with a slight decrease in activity.

Yingyong Huaxue published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C18H26ClN3O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yi, Wen-Bin published the artcileRare earth(III) perfluorooctanesulfonates catalyzed Friedel-Crafts alkylation in fluorous biphase system, Application of 2-Isopropylanisole, the publication is Journal of Fluorine Chemistry (2005), 126(5), 831-833, database is CAplus.

The catalyst of rare earth(III) perfluorooctanesulfonates (RE(OSO₂C₈F₁₇)₃, RE = Sc, Y, La-Lu) were prepared from either rare earth(III) chlorides or oxides and perfluorooctanesulfonic acid. The perflates thus obtained act as novel catalysts for Friedel-Crafts alkylation in fluorous biphasic system. Perfluorohexane (C₆F₁₄), perfluoromethylcyclohexane (C₇F₁₄), perfluorotoluene (C₇F₈), perfluorooctane (C₈F₁₈), perfluorooctyl bromide (C₈F₁₇Br), and perfluorodecalin (C₁₀F₁₈, cis- and trans-mixture) can be used as fluorous solvents for this reaction. By simple separation of the fluorous phase containing only catalyst, alkylation can be repeated many times.

Journal of Fluorine Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C3H8N2S, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bai, Yu published the artcileTunable synthesis of propylene glycol ether from methanol and propylene oxide under ambient pressure, SDS of cas: 1589-47-5, the publication is Kinetics and Catalysis (2011), 52(3), 386-390, database is CAplus.

A series of basic and acidic ionic liquids, 1-butyl-3-methylimidazolium hydroxide (BMIMOH), 1-acetyl-3-methylimidazolium chloride (AcMIMCl) and AcMIMCl-FeCl₃, or analogs of AcMIMCl, namely 1-potassium acetate-3-methylimidazolium chloride (KAcMIMCl), 1-potassium (sodium, ammonium) acetate-3-methylimidazolium hydroxides (KAcMIMOH, NaAcMIMOH and NH₄AcMIMOH), were prepared and used as catalysts for catalytic synthesis of propylene glycol ether via reaction of propylene oxide (PO) with methanol under mild reaction conditions. KAcMIMOH exhibited outstanding catalytic performance with 94.2% of conversion of PO and 99.1% of selectivity to 1-methoxy-2-propanol (MP-2) at 60°C and ambient pressure for 4 h. However, AcMIMCl-FeCl₃ showed a good catalysis performance with high selectivity to 2-methoxy-1-propanol (MP-1). The tunable synthesis of MP-2 or MP-1 catalyzed by basic compound KAcMIMOH or acidic ionic liquid AcMIMCl-FeCl₃ was realized.

Kinetics and Catalysis published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, SDS of cas: 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

De, Chunyan published the artcileHighly selective synthesis of propylene glycol ether from methanol and propylene oxide catalyzed by basic ionic liquid, Related Products of ethers-buliding-blocks, the publication is Journal of Chemical Technology and Biotechnology (2011), 86(1), 105-108, database is CAplus.

Propylene glycol ether is expected to be a safe substitute for toxic ethylene glycol ether usually used in industry owing to its negligible toxicity. Although catalysis of solid acids or bases for the synthesis of the ether can avoid separation of catalysts, liquid waste treatment and corrosion problems, it suffers from drawbacks, e.g. lower activity and selectivity to target product, high reaction pressure and temperature In order to solve these problems, a basic ionic liquid, namely choline hydroxide was prepared and used as a catalyst for synthesis of the ether via atom-economy reaction from propylene oxide and methanol. The ionic liquid showed excellent catalytic performance exhibiting 95.4% conversion of propylene oxide (PO) and 94.6% selectivity to 1-methoxy-2-propanol. It is also an effective catalyst for the reaction of PO with other primary alcs. to yield corresponding ethers. In addition this catalyst can be recovered and reused. The high activity and selectivity can probably be ascribed to its basicity and/or the strong polarity and electrostatic field of the reaction medium caused by the ionic liquid

Journal of Chemical Technology and Biotechnology published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Jiawei published the artcileNano metal oxides as efficient catalysts for selective synthesis of 1-methoxy-2-propanol from methanol and propylene oxide, COA of Formula: C4H10O2, the publication is RSC Advances (2018), 8(8), 4478-4482, database is CAplus.

Nano metal oxides such as Fe₂O₃, Fe₃O₄, CuO, NiO, ZnO and SnO₂ were prepared and characterized using XRD, SEM and TEM anal. These as-prepared metal oxide materials were used as catalysts for the etherification of methanol with propylene oxide (PO). The results showed that α-Fe₂O₃ exhibited outstanding catalytic performance with 97.7% conversion and 83.0% selectivity to MP-2 at 160 °C for 8 h. Furthermore, the relationship between the catalytic activity or selectivity and surface basicity or energy gap was investigated. This catalyst could be easily recovered and reused due to its heterogeneous catalytic nature.

RSC Advances published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C7H10N2O2, COA of Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem