Tag: 100-200

On December 31, 2012, Jiang, Tongzhou; He, Yong; Jian, Yu; Nie, Jun published an article.Product Details of 929-37-3 The title of the article was Exploration for decreasing the volume shrinkage for photopolymerization. And the article contained the following:

This article explored one method to decrease the volume shrinkage for photopolymerization including synthesis of a series of methacrylate-vinyl ether hybrid monomer, combination initiator system and introduction of chain transfer agent. Its photopolymerization kinetics was monitored by Fourier transform real-time IR spectroscopy (FTIR) and the volume shrinkage is measured by using laser displacement sensor (LDS), the adhesion strength is also evaluated. The results indicated that the volume shrinkage could be adjusted in some degree on demand which is good for adhesion strength. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Product Details of 929-37-3

The Article related to exploration decreasing volume shrinkage photopolymerization, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Product Details of 929-37-3

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Ether – Wikipedia,
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Alhamed, Samiyah; Alnakhli, Jawzah; Boadi, William; Beni, Ryan published an article in 2019, the title of the article was Triphenylmethanol conjugates of triptorelin as anti-lipid peroxidation prodrugs.Product Details of 321-28-8 And the article contains the following content:

Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable mols. that the body produces as a reaction to environmental and other pressures. Free radicals may play a role in heart disease, cancer and other diseases. If the body cannot process and remove free radicals efficiently, oxidative stress can result. This can harm cells and body function. Free radicals are also known as reactive oxygen species (ROS). In this research, Triptorelin (TRP) conjugates of triphenylmethanol derivatives (TPMs) were synthesized to evaluate their in vitro lipid peroxidation potency. Comparative lipid peroxidation assays between TRP-TPMs conjugates and the corresponding TPMs derivatives were measured using thiobarbituric reactive substance (TBARS) in a dose- and time-dependent manner following the Fenton’s pathway. Overall, TBARS decreased between 20% – 30% for the treated samples of synthesized conjugates compared to their resp. control phys. mixtures These data suggest that TRP-TPMs derivatives can be used to improve the biol. activity of TRP. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to triphenylmethanol triptorelin antilipid peroxidation, Pharmacology: Other (All Agents and Effects Not Otherwise Assignable) and other aspects.Product Details of 321-28-8

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 8, 2016, Sugihara, Shinji; Kawamoto, Yuki; Maeda, Yasushi published an article.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol The title of the article was Direct Radical Polymerization of Vinyl Ethers: Reversible Addition-Fragmentation Chain Transfer Polymerization of Hydroxy-Functional Vinyl Ethers. And the article contained the following:

Unprecedented controlled radical vinyl polymerization (CRP) of vinyl ethers using reversible addition-fragmentation chain transfer (RAFT) polymerization is reported. In order to overcome the challenge of direct radical polymerization of vinyl ethers, com. hydroxy-functional vinyl ethers such as 2-hydroxyethyl vinyl ether (HEVE) were subjected to free radical polymerization, generating vinyl polymers without polyacetals obtained by self-polyaddition polymerization In the case of bulk polymerization using a nonacidic azo-initiator such as di-Me 2,2′-azobis(2-methylpropionate), conventional free radical vinyl polymerization occurred with sufficiently high number-average mol. weight For example, poly(HEVE) was produced from the corresponding HEVE monomer with Mn = 26 400 in high yield, ≥75%. The resulting polymer was nearly identical to the polymer prepared by living cationic polymerization using the protected monomers except for the steric regularity (meso dyads are 51% and 67% for radical and cationic polymerizations, resp.). Furthermore, cyanomethyl methyl(phenyl)carbamodithioate was found to be an efficient RAFT agent, enabling the CRP of hydroxy-functional vinyl ethers. Under the polymerization conditions, poly(HEVE) macromol. chain transfer agent (macro-CTA) was prepared The kinetic studies of RAFT polymerization showed a linear increase of the mol. weight, with up to 50% monomer conversion and relatively low polydispersities (Mw/Mn < 1.38). In addition, chain extension experiments including block copolymerization with vinyl acetate and N-vinylpyrrolidone were demonstrated using the resulting poly(HEVE) macro-CTA to confirm the "livingness" of the poly(HEVE). The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Reference of 2-(2-(Vinyloxy)ethoxy)ethanol

The Article related to radical polymerization vinyl ether, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol

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On March 31, 2021, Wu, Zhuo; Wei, Feng; Wan, Bin; Zhang, Yanghui published an article.Application In Synthesis of 2-Methoxynaphthalene The title of the article was Pd-Catalyzed ipso,meta-Dimethylation of ortho-Substituted Iodoarenes via a Base-Controlled C-H Activation Cascade with Dimethyl Carbonate as the Methyl Source. And the article contained the following:

A Me group can have a profound impact on the pharmacol. properties of organic mols. Hence, developing methylation methods and methylating reagents is essential in medicinal chem. We report a palladium-catalyzed dimethylation reaction of ortho-substituted iodoarenes using di-Me carbonate as a Me source. In the presence of K2CO3 as a base, iodoarenes are dimethylated at the ipso- and meta-positions of the iodo group, which represents a novel strategy for meta-C-H methylation. With KOAc as the base, subsequent oxidative C(sp3)-H/C(sp3)-H coupling occurs; in this case, the overall transformation achieves triple C-H activation to form three new C-C bonds. These reactions allow expedient access to 2,6-dimethylated phenols, 2,3-dihydrobenzofurans, and indanes, which are ubiquitous structural motifs and essential synthetic intermediates of biol. and pharmacol. active compounds The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Application In Synthesis of 2-Methoxynaphthalene

The Article related to palladium catalyzed ipso meta dimethylation, dimethylation ortho substituted iodoarene, carbonhydrogen activation cascade reaction dimethyl carbonate methyl source, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Application In Synthesis of 2-Methoxynaphthalene

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Ether – Wikipedia,
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Vora, Harit U.; Silvestri, Anthony P.; Engelin, Casper J.; Yu, Jin-Quan published an article in 2014, the title of the article was Rhodium(II)-Catalyzed Nondirected Oxidative Alkenylation of Arenes: Arene Loading at One Equivalent.Reference of 1-Fluoro-2-methoxybenzene And the article contains the following content:

A bimetallic RhII catalyst promoted the C-H alkenylation of simple arenes at 1.0 equiv without the use of a directing group. A phosphine ligand as well as cooperative reoxidation of RhII with Cu(TFA)2 and V2O5 proved essential in providing monoalkenylated products in good yields and selectivities, especially with di- and trisubstituted arenes. E.g., in presence of [Rh2(OAc)4], tricyclohexylphosphine, Cu(TFA)2, and V2O5 in DCE under N2 at 140 °C, alkenylation of PhMe with Bu acrylate gave a 74% mixture (1:1) of (E)-I and (E)-II. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Reference of 1-Fluoro-2-methoxybenzene

The Article related to rhodium catalyst nondirected oxidative alkenylation arene, ch activation, alkenylation, bimetallic catalysts, homogeneous catalysis, rhodium, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Reference of 1-Fluoro-2-methoxybenzene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On December 31, 2020, Li, Yuqiang; Luo, Yixin; Peng, Long; Li, Yangyang; Zhao, Binzhi; Wang, Wang; Pang, Hailiang; Deng, Yi; Bai, Ruopeng; Lan, Yu; Yin, Guoyin published an article.Related Products of 321-28-8 The title of the article was Reaction scope and mechanistic insights of nickel-catalyzed migratory Suzuki-Miyaura cross-coupling. And the article contained the following:

In this work, a Ni-catalyzed migratory Suzuki-Miyaura cross-coupling featuring high benzylic or allylic selectivity has been developed. With this method, unactivated alkyl electrophiles and aryl or vinyl boronic acids can be efficiently transferred to diarylalkane or allylbenzene derivatives under mild conditions. Importantly, unactivated alkyl chlorides can also be successfully used as the coupling partners. To demonstrate the applicability of this method, showcase that this strategy can serve as a platform for the synthesis of terminal, partially deuterium-labeled mols. from readily accessible starting materials. Exptl. studies suggest that migratory cross-coupling products are generated from Ni(0/II) catalytic cycle. Theor. calculations indicate that the chain-walking occurs at a neutral nickel complex rather than a cationic one. In addition, the original-site cross-coupling products can be obtained by alternating the ligand, wherein the formation of the products has been rationalized by a radical chain process. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Related Products of 321-28-8

The Article related to diarylalkane allylbenzene derivative preparation nickel catalyst, alkyl electrophile aryl vinyl boronic acid suzuki miyaura coupling, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Related Products of 321-28-8

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, Han; Hu, Lingfei; Hu, Yanlei; Lv, Xiangying; Wu, Yan-Bo; Lu, Gang published an article in 2021, the title of the article was Origins of Lewis acid acceleration in nickel-catalyzed C-H, C-C and C-O bond cleavage.Safety of 2-Methoxynaphthalene And the article contains the following content:

The current understanding of Lewis acid effects on transition metal catalysis is generally based on the enhanced charge transfer from metal to substrate due to the formation of Lewis acid-base adducts. The critical factors of how Lewis acids manipulate complex catalyst-substrate interactions to facilitate reactions are seldom clarified. Herein, using the energy decomposition approach, we quantify the contributions of multiple factors which account for the Lewis acid acceleration in Ni-catalyzed C-X (X = H, C, O) bond cleavage via oxidative addition The results reveal that the dominant factors for Lewis acid promotion highly depend on the features of transition states with Lewis acids. In the transition states having only heteroatom-Lewis acid interactions (e.g., C-H, C-CN and C(acyl)-O oxidative additions), the reactivity is improved majorly by enhancing charge transfer from the metal to the Lewis acid-activated substrates, which is consistent with the conventional viewpoint. However, for the transition states with heteroatom-Lewis acid and heteroatom-transition metal interactions (e.g., C(benzyl)-O and C(aryl)-O oxidative additions), the decisive factor for the improved reactivity is ascribed to the reduced Pauli repulsion between occupied orbitals. Further, in the transition states having heteroatom-Lewis acid and Lewis acid-transition metal interactions (e.g., C(benzyl)-O oxidative addition), the reaction is facilitated by strengthening electrostatics and polarization due to greater charge separation and electron delocalization effects. These three types of dominant factors are generally employed by a series of different Lewis acids in promoting Ni-catalyzed bond cleavage. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene

The Article related to carbon hydrogen oxygen bond cleavage catalyst oxidative addition, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Safety of 2-Methoxynaphthalene

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Ether – Wikipedia,
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Mongin, Florence; Curty, Christophe; Marzi, Elena; Leroux, Frederic R.; Schlosser, Manfred published an article in 2015, the title of the article was Substituent effects on the relative rates and free energies of ortho-lithiation reactions: families of fluorobenzenes as the substrates.Category: ethers-buliding-blocks And the article contains the following content:

2-, 3- And 4-substituted fluorobenzenes and 5-substituted 1,3-difluorobenzenes were metalated with sec-butyllithium (LIS) and with lithium 2,2,6,6-tetramethylpiperidide (LiTMP) under irreversible conditions in order to determine the rates of reaction relative to the unsubstituted parent compounds (fluorobenzene and 1,3-difluorobenzene). In addition, the pairs of resulting aryllithiums were subjected to acid-base equilibration to furnish the thermodn. stabilities (or: basicities) of these species again relative to the parent compounds Not surprisingly, the effect diminishes with the distance of a given substituent to the lithiation center (ortho > meta > para) and it reaches its maximum at the ground state equilibration of the organometallic intermediate whereas it fades away at transition states, in particular reactant-like ones. Fluorine, the most powerful activator in the entire series if located at an ortho position, increases the rates of LIS- and LiTMP-promoted metalations by resp. 2 and 3 powers of ten, but by 7 to 8 powers of ten the aryllithium equilibrium stability. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Category: ethers-buliding-blocks

The Article related to fluorobenzene lithiation substituent effect kinetics equilibrium, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pratali Maffei, Luna; Faravelli, Tiziano; Cavallotti, Carlo; Pelucchi, Matteo published an article in 2020, the title of the article was Electronic structure-based rate rules for H ipso addition-elimination reactions on mono-aromatic hydrocarbons with single and double OH/CH3/OCH3/CHO/C2H5 substituents: a systematic theoretical investigation.Quality Control of 2-Methylanisole And the article contains the following content:

The recent interest in bio-oils combustion and the key role of mono-aromatic hydrocarbons (MAHs) in existing kinetic frameworks, both in terms of poly-aromatic hydrocarbons growth and surrogate fuels formulation, motivates the current systematic theor. investigation of one of the relevant reaction classes in MAHs pyrolysis and oxidation: ipso substitution by hydrogen. State-of-the-art theor. methods and protocols implemented in automatized computational routines allowed to investigate 14 different potential energy surfaces involving MAHs with hydroxy and Me single (phenol and toluene) and double (o-,m-,p-C6H4(OH)2, o-,m-,p-CH3C6H4OH, and o-,m-,p-C6H4(CH3)2) substituents, providing rate constants for direct implementation in existing kinetic models. The accuracy of the adopted theor. method was validated by comparison of the computed rate constants with the available literature data. Systematic trends in energy barriers, pre-exponential factors, and temperature dependence of the Arrhenius parameters were found, encouraging the formulation of rate rules for H ipso substitutions on MAHs. The rules here proposed allow to extrapolate from a reference system the necessary activation energy and pre-exponential factor corrections for a large number of reactions from a limited set of electronic structure calculations We were able to estimate rate constants for other 63 H ipso addn-elimination reactions on di-substituted MAHs, reporting in total 75 rate constants for H ipso substitution reactions o-,m-,p-R’C6H4R + H → C6H5R + R’, with R,R’ = OH/CH3/OCH3/CHO/C2H5, in the 300-2000 K range. Addnl. calculations performed for validation showed that the proposed rate rules are in excellent agreement with the rate constants calculated using the full computational protocol in the 500-2000 K range, generally with errors below 20%, increasing up to 40% in a few cases. The main results of this work are the successful application of automatized electronic structure calculations for the derivation of accurate rate constants for H ipso substitution reactions on MAHs, and an efficient and innovative approach for rate rules formulation for this reaction class. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Quality Control of 2-Methylanisole

The Article related to phenol toluene substitution reaction kinetics activation energy, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Quality Control of 2-Methylanisole

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On April 30, 2021, Jain, Suresh S.; Yadav, Ganapati D. published an article.Related Products of 578-58-5 The title of the article was Kinetic study for ionic liquid catalyzed green O-methylation of cresols using dimethyl carbonate. And the article contained the following:

In this work, we have systematically studied the kinetics and mechanism of ionic liquid catalyzed solvent less liquid-phase O-methylation of p-cresol with di-Me carbonate (DMC). The effect of various parameters such as mass transfer resistance, catalyst loading, mole ratio, initial CO2 pressure, and temperature was studied. The reaction was found to be pseudo zero order with respect to p-cresol and first order with respect to DMC. o- and m-Cresols were also used. The values of apparent activation energy for o-, m-, and p-cresol are found as 32.5, 34.0, and 32.5 kcal/mol, resp. Our study also suggests that type of cation and anion affects the catalytic acitivity of ionic liquids Ionic liquid, tetra Bu phosphonium bromide, offers excellent activity, selectivity, reusability, recyclability and stability. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Related Products of 578-58-5

The Article related to methylation cresol ionic liquid catalyst reaction kinetic study, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Related Products of 578-58-5

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem