Tag: 100-200

On June 8, 2021, Wang, Tao; Hoffmann, Marvin; Dreuw, Andreas; Hasagic, Edina; Hu, Chao; Stein, Philipp M.; Witzel, Sina; Shi, Hongwei; Yang, Yangyang; Rudolph, Matthias; Stuck, Fabian; Rominger, Frank; Kerscher, Marion; Comba, Peter; Hashmi, A. Stephen K. published an article.Application In Synthesis of 2-Methylanisole The title of the article was A Metal-Free Direct Arene C-H Amination. And the article contained the following:

Here, a metal-free arene e.g., mesitylene C-H amination using hydroxylamine derivatives 4-(CH3)C6H5S(O)2ON(R)R1 (R = H, Me; R1 = Me, Boc, Bn, etc.) under benign conditions was reported. A charge transfer interaction between the aminating reagents and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven exptl. In addition, this was rationalized by a theor. study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen mol. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole

The Article related to aryl amine preparation chemoselective, arene hydroxylamine amination, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Application In Synthesis of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 17, 2020, See, Yi Yang; Sanford, Melanie S. published an article.Quality Control of 2-Methylanisole The title of the article was C-H Amination of Arenes with Hydroxylamine. And the article contained the following:

This Letter describes the development of a TiIII-mediated reaction for the C-H amination of arenes with hydroxylamine. This reaction is applied to a variety of electron-rich (hetero)arene substrates, including a series of natural products and pharmaceuticals. It offers the advantages of mild conditions (room temperature), fast reaction rates (<30 min), compatibility with ambient moisture and air, scalability, and the use of inexpensive com. reagents. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Quality Control of 2-Methylanisole

The Article related to arene hydroxylamine titanium amination, aniline preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Quality Control of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 19, 1992, Achard, Daniel; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Electric Literature of 81616-80-0 The title of the patent was Preparation and reactions of thiopyranopyrroles and oxide derivatives. And the patent contained the following:

Title compounds I [R = H, allyl, or CR1R2R3, where R1 and R2 are H, (un)substituted Ph (with halo, alkyl, alkyloxy, NO2), and R3 is defined as for R1 or R2 or alkyl or alkyloxyalkyl, where at least one R1-3 is (un)substituted Ph, and n = 0-2], and isomers, are prepared by N-deprotection of the appropriate perhydrothiopyranopyrrole. Salts, isomers, and mixtures of isomers of these compounds are claimed. The above compounds are reacted with alkanoic acids R4CHR5CO2H [e.g., (2-methoxyphenyl)acetic acid] or with an imide analog to give claimed compounds N-substituted I [R = C(:Z)CHR4R5, n = 0-2, Z = O or NH, R4 = (un)substituted Ph (with halo, amino, alkylamino, etc., R5 = H, halo, OH, alkyl, etc.]. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Electric Literature of 81616-80-0

The Article related to thiopyranopyrrole oxide perhydro preparation reaction, perhydrothiopyranopyrrole oxide preparation reaction, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Electric Literature of 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 3, 1995, Grisoni, Serge; Huon, Christian; Peyronel, Jean-Francois published an article.HPLC of Formula: 81616-80-0 The title of the article was 4,4-Diphenyl-7-perhydrothiapyrano[3,4-c]pyrrolone, a new series of substance P receptors antagonists. And the article contained the following:

The synthesis of 4,4-diphenyl-7-perhydrothiapyrano[3,4-c]pyrrolones, a new series of substance P antagonists with high affinity for rat and human NK1 receptors is described. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).HPLC of Formula: 81616-80-0

The Article related to diphenylperhydrothiapyranopyrrolone substance p receptor antagonists, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.HPLC of Formula: 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 21, 2021, Singh, Bhagat; Ahmed, Jasimuddin; Biswas, Amit; Paira, Rupankar; Mandal, Swadhin K. published an article.Synthetic Route of 93-04-9 The title of the article was Reduced Phenalenyl in Catalytic Dehalogenative Deuteration and Hydrodehalogenation of Aryl Halides. And the article contained the following:

Dehalogenative deuteration reactions are generally performed through metal-mediated processes. This report demonstrates a mild protocol for hydrodehalogenation and dehalogenative deuteration of aryl/heteroaryl halides (39 examples) using a reduced odd alternant hydrocarbon phenalenyl under transition metal-free conditions and has been employed successfully for the incorporation of deuterium in various biol. active compounds The combined approach of exptl. and theor. studies revealed a single electron transfer-based mechanism. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Synthetic Route of 93-04-9

The Article related to aryl heteroaryl halide deuteration hydrodehalogenation, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Synthetic Route of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dal Poggetto, Guilherme; Favaro, Denize C.; Nilsson, Mathias; Morris, Gareth A.; Tormena, Claudio F. published an article in 2014, the title of the article was 19F DOSY NMR analysis for spin systems with nJFF couplings.Electric Literature of 321-28-8 And the article contains the following content:

NMR is a powerful method for identification and quantification of drug components and contaminations. These problems present themselves as mixtures, and here, one of the most powerful tools is DOSY. DOSY works best when there is no spectral overlap between components, so drugs containing fluorine substituents are well-suited for DOSY anal. as 19F spectra are typically very sparse. Here, the authors demonstrate the use of a modified 19F DOSY experiment (from the Oneshot sequences) for various fluorinated benzenes. For compounds with significant nJFF coupling constants, as is common, the undesirable J-modulation can be efficiently suppressed using the Oneshot45 pulse sequence. This study highlights 19F DOSY as a valuable and robust method for anal. of mol. systems containing fluorine atoms even where there are large fluorine-fluorine couplings. Copyright © 2014 John Wiley and Sons, Ltd. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Electric Literature of 321-28-8

The Article related to fluorine dosy nmr spin system njff coupling, 19f, dosy, Physical Organic Chemistry: Resonance Spectra (Electron Spin, Nuclear Magnetic and Fourier Transform Nuclear Magnetic, Quadrupole, etc.) and other aspects.Electric Literature of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Becerra-Martinez, Elvia; Perez-Hernandez, Nury; Sanchez-Zavala, Maricruz; Melendez-Rodriguez, Myriam; Aristeo-Dominguez, Alberto; Suarez-Castillo, Oscar R.; Joseph-Nathan, Pedro published an article in 2022, the title of the article was Equilibrating magnetic dispersion and magnet homogeneity for the high-resolution proton nuclear magnetic resonance of monosubstituted naphthalenes.Recommanded Product: 2-Methoxynaphthalene And the article contains the following content:

Accurate chem. shift and coupling constant for 1- and 2-naphthyl derivatives were decipher by iterative full spin anal. Each of the seven magnetically nonequivalent H2-H8 atoms in 1-naphthyl derivatives, or of the H1, H3-H8 atoms in 2-naphthyl derivatives were unambiguously identified by analyzing their intra- and inter-ring coupling constants at 300 MHz and by two-dimensional homo- and heteronuclear experiments at 750 MHz. 13C chem. shifts were also determined during this study, from where some literature ambiguities were resolved using long-range C-H correlations at 750 MHz. The complete proton NMR parameters are herein ascribed for the first time. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to naphthalene substituent effect carbon nmr, Physical Organic Chemistry: Resonance Spectra (Electron Spin, Nuclear Magnetic and Fourier Transform Nuclear Magnetic, Quadrupole, etc.) and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Arai, Kenta; Ueda, Yoshihiro; Morisaki, Kazuhiro; Furuta, Takumi; Sasamori, Takahiro; Tokitoh, Norihiro; Kawabata, Takeo published an article in 2018, the title of the article was Intermolecular chemo- and regioselective aromatic C-H amination of alkoxyarenes promoted by rhodium nitrenoids.Product Details of 321-28-8 And the article contains the following content:

Intermol. aromatic C(sp2)-H amination promoted by neutral rhodium nitrenoids has been developed. The reactions proceeded with various oxygen-substituted arenes ROR1 (R = Me, Et, Bn, etc.; R1 = Ph, 2-fluorophenyl, 2-benzylphenyl, etc.) (1.5 equivalent) in a chemo- and regioselective manner. The aromatic C(sp2)-H amination took place at the para position of the oxygen substituent in the presence of benzylic C(sp3)-H bonds and/or C(sp3)-H bonds α to ethereal oxygen. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to aryl carbamate preparation chemoselective regioselective, alkoxyarene tosyl trichloroethoxycarbonyl hydroxylamine amination dirhodium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Product Details of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 20, 2022, Kwon, Tae-woo; Song, Bo; Nam, Kwan Woo; Stoddart, J. Fraser published an article.Reference of 1,4-Dimethoxybenzene The title of the article was Mechanochemical Enhancement of the Structural Stability of Pseudorotaxane Intermediates in the Synthesis of Rotaxanes. And the article contained the following:

Mechanochem. syntheses of rotaxanes have attracted considerable attention of late because of the superior reaction rates and higher yields associated with their production compared with analogous reactions carried out in solution Previous investigators, however, have focused on the demonstration of the mechanochem. syntheses of rotaxanes per se, rather than on studying the solid-phase host-guest mol. interplay related to their rapid formation and high yields. In this investigation, the lower yields of rotaxanes prepared in solution were attributed to the limited concentration and a desolvation energy penalty that must be compensated for by host-guest interactions during complexation that precedes the templation leading to rotaxane formation. It follows that, if the desolvation energy can be removed and higher concentrations can be attained, even weak host-guest interactions can drive the complexation of host and guest mols. efficiently. In order to test this hypothesis, two host-guest pairs of permethylated pillar[5]arene/ 1,6-diaminohexane and permethylated pillar[5]arene/ 2,2′-(ethylenedioxy)bis(ethylamine) have been chosen for the simple reason that they exhibit extremely low binding constants (2.7 ± 0.4 M-1 when 1,6-diaminohexane is the guest and <0.1 M-1 when 2,2'-(ethylenedioxy)bis(ethylamine) is the guest in CDCl3; i.e., ostensibly no pseudorotaxane formation is observed). It can be argued that the amount of pseudorotaxanes formed in the solid state is responsive to mech. treatments or otherwise and changes in temperature during stoppering reactions. Compared to the amount of pseudorotaxanes that can be obtained in solution, large quantities of pseudorotaxanes are formed in the solid state because of concentration and desolvation effects. This mechanochem. enhancement of pseudorotaxane formation is referred to as a self-correction in the current investigation. Rotaxanes based on permethylated pillar[5]arene/ 1,6-diaminohexane and permethylated pillar[5]arene/ 2,2'-(ethylenedioxy)bis(ethylamine) have been synthesized in much higher yields compared to those obtained in solution, aided and abetted by self-correction effects during mech. treatments and heating at a mild temperature of 50°C. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Reference of 1,4-Dimethoxybenzene

The Article related to pseudorotaxane preparation structural stability mechanochem enhancement, rotaxane preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Higher-Membered Ring Systems, Including Cyclophanes and Fullerenes and other aspects.Reference of 1,4-Dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 15, 2020, Verevkin, Sergey P.; Pimerzin, Andrey A.; Sun, Li-Xian published an article.Recommanded Product: 578-58-5 The title of the article was Structure-property relationships in substituted diphenyl ethers: Non-nearest interactions of methyl-, methoxy-, hydroxyl-, amino-, and nitro-substituents. And the article contained the following:

The standard molar enthalpies of formation, ΔfHom(liq/cr) of di-Ph ether substituted with nitro substituents were measured by the high-precision combustion calorimetry. Enthalpies of vaporisation/sublimation Δgl,crHom(298.15 K) of these compounds were obtained by the transpiration method. Enthalpies of fusion were measured by DSC. Gas-phase enthalpies of formation ΔfHom(g, 298.15 K) of substituted di-Ph ethers calculated by the G4 method were in an excellent agreement with the exptl. results. A set of thermodn. properties of di-Ph ether derivatives of benchmark quality was recommended for thermochem. calculations and for quantification of non-nearest interactions of methyl-, methoxy-, hydroxyl-, amino- and nitro-substituents on the di-Ph ether aromatic system. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 578-58-5

The Article related to diphenyl methyl methoxy hydroxyl nitro ether structure property, Phase Equilibriums, Chemical Equilibriums, and Solutions: Other Chemical Equilibriums (Without Mechanistic Or Kinetic Interest) and other aspects.Recommanded Product: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem