Tag: 100-200

On May 15, 2020, Wang, Jing-Hao; Lei, Tao; Wu, Hao-Lin; Nan, Xiao-Lei; Li, Xu-Bing; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published an article.Category: ethers-buliding-blocks The title of the article was Thiol Activation toward Selective Thiolation of Aromatic C-H Bond. And the article contained the following:

An effective model for regioselective thiolation of the aromatic C-H bond by thiol activation instead of arene activation was disclosed. This method was applied into anisole derivatives that are not available in the arene activation approach to forge a single thioether isomer with high reactivity. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Category: ethers-buliding-blocks

The Article related to thiophenol aryl ether regioselective electrochem thiolation, diaryl thioether preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 15, 2020, Wang, Jing-Hao; Lei, Tao; Wu, Hao-Lin; Nan, Xiao-Lei; Li, Xu-Bing; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published an article.Computed Properties of 93-04-9 The title of the article was Thiol Activation toward Selective Thiolation of Aromatic C-H Bond. And the article contained the following:

An effective model for regioselective thiolation of the aromatic C-H bond by thiol activation instead of arene activation was disclosed. This method was applied into anisole derivatives that are not available in the arene activation approach to forge a single thioether isomer with high reactivity. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9

The Article related to thiophenol aryl ether regioselective electrochem thiolation, diaryl thioether preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Computed Properties of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhu, Runqing; Sun, Qianqian; Li, Jing; Li, Luohao; Gao, Qinghe; Wang, Yakun; Fang, Lizhen published an article in 2021, the title of the article was para-selective hydroxylation of alkyl aryl ethers.Electric Literature of 578-58-5 And the article contains the following content:

Para-Selective hydroxylation of alkyl aryl ethers is established, which proceeds with a ruthenium(II) catalyst, hypervalent iodine(III) and trifluoroacetic anhydride via a radical mechanism. This protocol tolerates a wide scope of substrates and provides a facile and efficient method for preparing clin. drugs monobenzone and pramocaine on a gram scale. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Electric Literature of 578-58-5

The Article related to alkyl aryl ether para hydroxylation regioselective, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Electric Literature of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pirzer, Anna S.; Alvarez, Eva-Maria; Friedrich, Heike; Heinrich, Markus R. published an article in 2019, the title of the article was Radical Carbofluorination of Alkenes with Arylhydrazines and Selectfluor: Additives, Mechanistic Pathways, and Polar Effects.Formula: C7H7FO And the article contains the following content:

Radical carbofluorination reactions starting from arylhydrazines and nonactivated alkenes, in which the C-F bond is formed through the use of Selectfluor, can be improved through the addition of anisole. Because direct trapping products could be detected only in trace amounts, anisole does primarily act as a reversible scavenger for the highly reactive ammonium radical dication released from Selectfluor in the C-F bond-forming step. As shown for three diverse substitution patterns, the main role of anisole is to prevent, or at least reduce, the undesired addition of the ammonium radical dication to the alkene, which in turn leads to an unfavorable consumption of the arylhydrazine-derived precursors required for carbofluorination. Moreover, besides the remarkable polar effects in radical trapping, this study shows that the Selectfluor-derived nitrogen-centered radical dication may add directly to alkenes, which has not been described so far. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Formula: C7H7FO

The Article related to radical carbofluorination alkene arylhydrazine selectfluor mechanism polar effect, selectfluor, alkenes, anisole, fluorination, radical reactions, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydroxylamines, Hydrazines, Triazenes, Azides, Azines, and Azo and Diazo Compounds and other aspects.Formula: C7H7FO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 19, 1992, Achard, Daniel; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Product Details of 81616-80-0 The title of the patent was Preparation of thiopyranopyrrole derivatives as substance P antagonists. And the patent contained the following:

The preparation of perhydrothiopyranopyrroles and oxide derivatives I [Z = O, NH; R1 = (un)substituted Ph, cyclohexadienyl, naphthyl, heterocyclyl; R2 = H, halo, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, acyloxy, carboxy, alkoxycarbonyl, benzyloxycarbonyl, amino, acylamino; n = 0-2], stereoisomers and their mixtures, and salts is claimed. The compounds are particularly interesting as substance P antagonists. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Product Details of 81616-80-0

The Article related to thiopyranopyrrole perhydro preparation antagonist substance p, perhydrothiopyranopyrrole preparation antagonist substance p, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Product Details of 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 15, 2020, Yang, Qing-Yu; Zhang, You-Ming; Ma, Xiao-Qiang; Dong, Hong-Qiang; Zhang, Yun-Fei; Guan, Wen-Li; Yao, Hong; Wei, Tai-Bao; Lin, Qi published an article.HPLC of Formula: 150-78-7 The title of the article was A pillar[5]arene-based fluorescent sensor for sensitive detection of L-Met through a dual-site collaborative mechanism. And the article contained the following:

L-Methionine (L-Met) is one of the essential amino acids in human health, efficiently detect L-Met is a significant issue. Herein, a concept “dual-site collaborative recognition” had been successfully introduced into the design and achieved high selective and sensitive recognition of L-Met. In order to realize the “dual-site collaborative recognition”, the authors rationally designed and synthesized an ester functionalized pillar[5]arene-based fluorescent sensor (SP5). And it shows blue Aggregation-induced emission (AIE) fluorescence. In the SP5, the pillar[5]arene group act as C-H···π interactions site, and ester group serve as multi hydrogen bonding acceptor. The SP5 exhibited high selectivity and sensitivity (2.84 × 10-8 M) towards L-Met based on the collaboration of electron-rich cavernous pillar[5]arene group and ester group through C-H···π and H-bond interactions, resp. This “dual-site collaborative recognition” mechanism has been studied by 1H NMR, ESI-MS and theor. calculation including frontier orbital (HOMO and LUMO), electrostatic potential (ESP) and the noncovalent interaction (NCI). These theor. calculations not only support the proposed host-guest recognition mechanism, but also provided visualized information on the “dual-site collaborative recognition” mode. Furthermore, the concept “dual-site collaborative recognition” is an effective strategy for easily detecting biol. mols. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).HPLC of Formula: 150-78-7

The Article related to pillararene based fluorescent probe met dual site collaborative mechanism, aiegen, dft calculation, dual-site collaborative recognition, fluorescent sensor, pillar[n]arenes and other aspects.HPLC of Formula: 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 8, 2021, Deolka, Shubham; Govindarajan, Ramadoss; Khaskin, Eugene; Fayzullin, Robert R.; Roy, Michael C.; Khusnutdinova, Julia R. published an article.Quality Control of 2-Methoxynaphthalene The title of the article was Photoinduced Trifluoromethylation of Arenes and Heteroarenes Catalyzed by High-Valent Nickel Complexes. And the article contained the following:

Authors describe a series of air-stable NiIII complexes supported by a simple, robust naphthyridine-based ligand. Access to the high-valent oxidation state is enabled by the CF3 ligands on the nickel, while the naphthyridine exhibits either a monodentate or bidentate coordination mode that depends on the oxidation state and sterics, and enables facile aerobic oxidation of NiII to NiIII. These NiIII complexes act as efficient catalysts for photoinduced C(sp2)-H bond trifluoromethylation reactions of (hetero)arenes using versatile synthetic protocols. This blue LED light-mediated catalytic protocol proceeds via a radical pathway and demonstrates potential in the late-stage functionalization of drug analogs. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Quality Control of 2-Methoxynaphthalene

The Article related to arene heteroarene photoinduced trifluoromethylation high valent nickel complex, c−h bond functionalization, nickel, photoreactivity, radical formation, trifluoromethylation and other aspects.Quality Control of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 31, 2022, Kurbanoglu, Sevinc; Cevher, Sevki Can; Toppare, Levent; Cirpan, Ali; Soylemez, Saniye published an article.Application of 91-16-7 The title of the article was Electrochemical biosensor based on three components random conjugated polymer with fullerene (C60). And the article contained the following:

Herein, a conjugated polymer and fullerene bearing architecture-based electrochem. Tyrosinase (Tyr) enzyme inhibition biosensor for indomethacin (INDO) drug active compound has been developed. For this purpose, three moieties of benzoxadiazole, thienopyrroledione, and benzodithiophene containing conjugated polymer; poly[BDT-alt-(TP;BO)] was used as a transducer modifier together with fullerene for catechol detection. The specific combination of these materials is considered an effective way to fabricate highly sensitive and fast response catechol biosensors for the first time. Electrochem. and surface characteristics of the modified electrodes were obtained by cyclic voltammetry, electrochem. impedance spectroscopy, SEM, and at. force microscopy. The effect of the parameters during chronoamperometric measurements on the biosensor response was also studied. Using optimized conditions, biosensing of catechol was achieved between 0.5 and 62.5 μM with a limit of the detection 0.11 μM. Tyr inhibition was followed with INDO drug active compound and it was found that INDO has a mixed type characteristic of enzyme kinetics with an I50 value of 15.11 μM. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Application of 91-16-7

The Article related to graphite electrode polymer fullerene tyrosinase electrochem biosensor, catechol detection, conjugated random polymer, enzyme inhibition, fullerene, indomethacin, tyrosinase and other aspects.Application of 91-16-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 25, 2021, Yang, Zongfan; Chen, Pei; Hao, Wenjing; Xie, Zhen; Feng, Yu; Xing, Guolong; Chen, Long published an article.Product Details of 91-16-7 The title of the article was Sulfonated 2D Covalent Organic Frameworks for Efficient Proton Conduction. And the article contained the following:

Open 1D channels found in covalent organic frameworks are unique and promising to serve as pathways for proton conduction; how to develop high-rate yet stable transporting systems remains a substantial challenge. Herein, this work reports a strategy for exploring proton-conducting frameworks by engineering pore walls and installing proton-containing polymers into the pores. Amide-linked and sulfonated frameworks were synthesized from imine-linked precursors via sequentially engineering to oxidize into amide linkages and to further anchor sulfonic acid groups onto the pore walls, enabling the creation of sulfonated frameworks with high crystallinity and channel ordering. Integrating sulfonated polyether ether ketone chains into the open channels enables proton hopping to across the channels, greatly increases proton conductivity and enables a stable continuous run. These results suggest a way to explore proton-conducting COFs via systematic engineering of the wall and space of the open nanochannels. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Product Details of 91-16-7

The Article related to sulfonated covalent organic framework proton conductivity crystallinity nanochannel, covalent organic frameworks, post-synthesis, proton conduction, stability, sulfonation and other aspects.Product Details of 91-16-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lewandowski, Andrzej; Szymczyk, Katarzyna published an article in 2020, the title of the article was Partitioning of selected anisole and veratrole derivatives between water and anionic surfactant micelles.Name: 1,2-Dimethoxybenzene And the article contains the following content:

The UV absorption spectra of six structurally related derivatives of anisole and veratrole, i.e., anisaldehyde, (E)-anethole, estragole, veratraldehyde, methyleugenol and (E)-methylisoeugenol, were recorded at various concentrations of the anionic surfactants, either sodium lauryl sulfate (SLS) or sodium lauryl ether sulfate (SLES) at T = 298 K. In addition, conductivity and d. measurements were made for the SLS and SLES solutions to determine the volumetric properties of the studied surfactants. Next, using the W. Al-Soufi, L. Pieiro and M. Novo model (APN model) including the pseudo-phase model for micellar solubilization, the values of micelle-water partition coefficients for each perfume-surfactant system were determined In addition, the relations between the mol. structures of the solute and the head group of the surfactant and the value of the micelle-water partition coefficient as well as the octanol-water one were discussed. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Name: 1,2-Dimethoxybenzene

The Article related to anisole veratrole derivative anionic surfactant micelle partitioning elec conductivity, apn model, sles, sls, anisole and veratrole derivatives, micelle-water partitioning and other aspects.Name: 1,2-Dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem