Tag: 100-200

On September 6, 2021, Quan, Qinzhi; Ma, Mingyu; Wang, Zongtao; Gu, Yu; Chen, Mao published an article.Computed Properties of 929-37-3 The title of the article was Visible-Light-Enabled Organocatalyzed Controlled Alternating Terpolymerization of Perfluorinated Vinyl Ethers. And the article contained the following:

Polymerizations of perfluorinated vinyl ethers (PFVEs) provide an important category of fluoropolymers that have received considerable interests in applications. In this work, we report the development of an organocatalyzed controlled radical alternating terpolymn. of PFVEs and vinyl ethers (VEs) under visible-light irradiation This method not only enables the synthesis of a broad scope of fluorinated terpolymers of low dispersities and high chain-end fidelity, facilitating tuning the chem. compositions by rationally choosing the type and/or ratio of comonomers, but also allows temporal control of chain-growth, as well as the preparation of a variety of novel fluorinated block copolymers. To showcase the versatility of this method, fluorinated alternating terpolymers were synthesized and customized to simultaneously display a variety of desirable properties for solid polymer electrolyte design, creating new opportunities in high-performance energy storage devices. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Computed Properties of 929-37-3

The Article related to visible light organocatalyst radical alternating terpolymn perfluorinated vinyl ether, fluoropolymer alternating copolymer block electrolyte solid electrolyte, controlled radical polymerization, fluorine, photocatalysis, synthetic methods, terpolymer and other aspects.Computed Properties of 929-37-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 23, 2009, Hartz, Richard A.; Ahuja, Vijay T.; Arvanitis, Argyrios G.; Rafalski, Maria; Yue, Eddy W.; Denhart, Derek J.; Schmitz, William D.; Ditta, Jonathan L.; Deskus, Jeffrey A.; Brenner, Allison B.; Hobbs, Frank W.; Payne, Joseph; Lelas, Snjezana; Li, Yu-Wen; Molski, Thaddeus F.; Mattson, Gail K.; Peng, Yong; Wong, Harvey; Grace, James E.; Lentz, Kimberley A.; Qian-Cutrone, Jingfang; Zhuo, Xiaoliang; Shu, Yue-Zhong; Lodge, Nicholas J.; Zaczek, Robert; Combs, Andrew P.; Olson, Richard E.; Bronson, Joanne J.; Mattson, Ronald J.; Macor, John E. published an article.Quality Control of (S)-1-Methoxypropan-2-amine hydrochloride The title of the article was Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of N3-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists. And the article contained the following:

Evidence suggested that corticotropin-releasing factor-1 (CRF1) receptor antagonists may offer therapeutic potential for the treatment of diseases associated with elevated levels of CRF such as anxiety and depression. A pyrazinone-based chemotype of CRF1 receptor antagonists was discovered. Structure-activity relationship studies led to the identification of numerous potent analogs including I, a highly potent and selective CRF1 receptor antagonist with an IC50 value of 0.26 nM. The pharmacokinetic properties of I were assessed in rats and Cynomolgus monkeys. Compound I was efficacious in the defensive withdrawal test (an animal model of anxiety) in rats. The synthesis, structure-activity relationships and in vivo properties of compounds, e.g., I, within the pyrazinone chemotype were described. The experimental process involved the reaction of (S)-1-Methoxypropan-2-amine hydrochloride(cas: 1162054-86-5).Quality Control of (S)-1-Methoxypropan-2-amine hydrochloride

The Article related to pyrazinone arylamino asym preparation corticotropin releasing factor receptor antagonist, arylamino pyrazinone corticotropin releasing factor receptor antagonist sar activity, anxiolytic agent pyrazinone arylamino crf receptor antagonist sar activity and other aspects.Quality Control of (S)-1-Methoxypropan-2-amine hydrochloride

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On December 31, 2022, Ji, Peng; Davies, Cassondra C.; Gao, Feng; Chen, Jing; Meng, Xiang; Houk, Kendall N.; Chen, Shuming; Wang, Wei published an article.Computed Properties of 93-04-9 The title of the article was Selective skeletal editing of polycyclic arenes using organophotoredox dearomative functionalization. And the article contained the following:

A general organophotoredox approach for the chemo- and regioselective dearomatization of structurally diverse polycyclic aromatics, including quinolines, isoquinolines, quinoxalines, naphthalenes, anthracenes and phenanthrenes was described. The success of the method for chemoselective oxidative rupture of aromatic moieties relies on precise manipulation of the electronic nature of the fused polycyclic arenes. Mechanistic studies show that the addition of a hydrogen atom transfer (HAT) agent helps favor the dearomatization pathway over the more thermodynamically downhill aromatization pathway. This strategy was applied to rapid synthesis of biol. valued targets and late-stage skeletal remodeling en route to complex structures. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9

The Article related to arene azole acridinium photocatalyst chemoselective regioselective dearomatization, azolyl dihydroarene preparation, carboxylic acid arene acridinium photocatalyst chemoselective regioselective dearomatization, dihydroaryl alkanoate preparation and other aspects.Computed Properties of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 27, 2020, Zhang, Dao; Yu, Jueqin published an article.Safety of 2-Methoxynaphthalene The title of the article was Fine Tuning of Chiral Bis(N-heterocyclic carbene) Palladium Catalysts for Asymmetric Suzuki-Miyaura Cross-Coupling Reactions: Exploring the Ligand Modification. And the article contained the following:

Novel chiral N,N’-bisaryl bis(NHC) ligand precursors H2[(S)-2]Cl2 on a spiro scaffold and H2[(S)-3b-g]Cl2 with a binaphthyl linkage were rationally designed and their cyclometalated cis-chelated NHC Pd complexes (S)-5, (S)-6, and (S)-7b-g were synthesized and fully characterized. Complexes 6 and 7b were further confirmed by x-ray single-crystal anal. Both complexes adopted a slightly distorted square planar geometry around the Pd(II) center. The structure of 6 consists of a rare dimeric arrangement incorporating two Pd(II) centers bonded through a short metal-metal bond (2.853(2) Å), indicating a PdII-PdII intramol. interaction (<3.00 Å). These N,N'-bisaryl-bis(NHC)-Pd complexes together with N,N'-bisalkyl analogs {[(S)-1a-d]PdX2} (X = I, (S)-4a; X = Br, (S)-4b-d) were used in the asym. aryl-aryl cross-coupling reactions of arylboronic acids and aryl halides. The enantioselectivity of the biaryl products was greatly improved within 24 h (up to 74% ee) when complexes 7a-g were used as catalysts. For these types of bis(NHC) Pd catalysts the structural characters of the chiral scaffolds play a decisive role in the enantioselectivities of cross-coupling reactions. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene

The Article related to spirobiindenediylbisdiamine palladacycle carbene complex preparation catalyst suzuki reaction, crystal structure spirobiindenediylbisdiamine palladacycle carbene complex, mol structure spirobiindenediylbisdiamine palladacycle carbene complex and other aspects.Safety of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 1, 2022, Dalai, Pallaba Ganjan; Palit, Kuntal; Panda, Niranjan published an article.Synthetic Route of 93-04-9 The title of the article was Generation of Dimethyl Sulfoxide Coordinated Thermally Stable Halogen Cation Pools for C-H Halogenation. And the article contained the following:

A method to generate halogen cation pools from the reaction of 1,2-dihaloethanes (hal=Br, I) and DMSO (DMSO) for C-H halogenation of arenes and heteroarenes was reported. The initial reaction of DMSO and 1,2-dihaloethane generates the sulfur ylide, which undergoes pyrolytic elimination of ethylene by affording halonium ions. These ions were accumulated and stabilized by DMSO through coordination by forming halogen cation pools for the halogenation reaction. This protocol was selective for electrophilic monohalogenation of arenes at room temperature; however, polyhalogenated products were formed by raising the reaction temperature Late-stage halogenation of heteroarenes and some commonly marketed drugs signifies the synthetic utility of this protocol in pharmaceutical chem. Unlike the classical methods, the in-situ generated electrophilic bromonium ion was further exploited for the direct synthesis of α-diketones from the alkenes under base-free conditions. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Synthetic Route of 93-04-9

The Article related to arene dmso coordinated halogen halogenation, haloarene preparation, alkene dmso coordinated bromide halogenation, dibromoalkane preparation, diketone preparation, enamide dmso coordinated bromide intramol cyclization, oxazole preparation and other aspects.Synthetic Route of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mandrelli, Francesca; Blond, Aurelie; James, Thomas; Kim, Hyejin; List, Benjamin published an article in 2019, the title of the article was Deracemizing α-Branched Carboxylic Acids by Catalytic Asymmetric Protonation of Bis-Silyl Ketene Acetals with Water or Methanol.Electric Literature of 81616-80-0 And the article contains the following content:

We report a highly enantioselective catalytic protonation of bis-silyl ketene acetals. Our method delivers α-branched carboxylic acids, including nonsteroidal anti-inflammatory arylpropionic acids such as Ibuprofen, in high enantiomeric purity and high yields. The process can be incorporated in an overall deracemization of α-branched carboxylic acids, involving a double deprotonation and silylation followed by the catalytic asym. protonation. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Electric Literature of 81616-80-0

The Article related to alpha branched carboxylic acid catalytic asym protonation deracemization, enantioselective catalytic protonation bissilyl ketene acetal, brønsted acids, bis-silyl ketene acetals, deracemization, deuteration, disulfonimide, protonation and other aspects.Electric Literature of 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nguyen, Ngoc-Lan Thi; Nguyen, Quoc-Anh; Le, Tien Khoa; Luu, Thi Xuan Thi; Tran, Kim-Ngan Thi; Pham, Phuoc-Bao published an article in 2022, the title of the article was Chloroaluminate Ionic Liquid Immobilized on Magnetic Nanoparticles as a Heterogeneous Lewis Acidic Catalyst for the Friedel-Crafts Sulfonylation of Aromatic Compounds.Synthetic Route of 150-78-7 And the article contains the following content:

Chloroaluminate ionic liquid bound on magnetic nanoparticles (Fe3O4@O2Si[PrMIM]Cl·AlCl3) was prepared and used as a heterogenous Lewis acidic catalyst for the Friedel-Crafts sulfonylation of aromatic compounds with sulfonyl chlorides or p-toluenesulfonic anhydride. The catalyst′s stability, efficiency, easy recovery, and high recyclability without considerable loss of catalytic capability after four recycles were evidence of its advantages. Furthermore, the stoichiometry, wide substrate scope, short reaction time, high yield of sulfones, and solvent-free reaction condition also made this procedure practical, ecofriendly, and economical. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Synthetic Route of 150-78-7

The Article related to chloroaluminate ionic liquid immobilization magnetic nanoparticle, heterogeneous lewis acidic catalyst friedel crafts sulfonylation aromatic compound, ionic liquids, magnetic nanoparticles, sulfones, sulfonic anhydride, sulfonylation and other aspects.Synthetic Route of 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 1, 2022, Sahoo, Kanchanbala; Panda, Niranjan published an article.Application In Synthesis of 2-Methylanisole The title of the article was Iron(III) Chloride Mediated para-Selective C-H Functionalization: Access to C5-Chloro and C5,C7-Dichloro/Dianisyl Substituted 2-Arylbenzoxazoles. And the article contained the following:

Iron(III) chloride mediated para-selective C-H chlorination and subsequent annulation of 2-amidophenol to synthesize C5- and C5, C7-chlorinated benzoxazoles was developed. Further, the oxidative cross-dehydrogenative coupling of amidophenol with anisole by ferric chloride was explored to achieve the remotely anisylated benzoxazoles. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole

The Article related to amidophenol iron chloride regioselective chlorination heterocyclization, chloro benzoxazole preparation, methoxybenzene amidophenol iron chloride heterocyclization cross dehydrogenative coupling, methoxyphenyl benzoxazole preparation and other aspects.Application In Synthesis of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 28, 2022, Zhang, Dao; Yu, Jueqin published an article.Reference of 2-Methoxynaphthalene The title of the article was Effect of the Dihedral Angle of Biaryl-Bridged Bis(N-Heterocylic Carbene) Ligands on Enantioselectivity in Pd-Catalyzed Asymmetric Aryl-Aryl Cross-Coupling. And the article contained the following:

New biaryl-bridged bis(N-heterocylic carbene) Pd complexes were synthesized and applied in asym. Suzuki cross-coupling of aryl halide and aryl boronic acid. X-ray crystallog. studies of square-planar Pd complexes of four of these bis(NHC) ligands revealed that the dihedral angle of the bridging biaryl moiety depends on its identity and lies 79.65-92.69°. A linear correlation between the dihedral angle in these Pd complexes and cross-coupling enantioselectivity is 1st reported. Also, larger Ccarbene-Pd-Ccarbene bite angles lead to increased enantioselectivity in a 1st fast and then slow growing tendency. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Reference of 2-Methoxynaphthalene

The Article related to chiral biarylbenzimidazolylidene palladacycle complex preparation suzuki reaction catalyst, crystal structure chiral biarylbenzimidazolylidene palladacycle complex, mol structure chiral biarylbenzimidazolylidene palladacycle complex and other aspects.Reference of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mondal, Haripriyo; Sk, Raja Md; Maji, Modhu Sudan published an article in 2020, the title of the article was Cooperativity within the catalyst: alkoxyamide as a catalyst for bromocyclization and bromination of (hetero)aromatics.Recommanded Product: 2-Methoxynaphthalene And the article contains the following content:

N-Methoxy-1-butanesulfonamide was a recyclable catalyst for the activation of N-bromosuccinimide to perform bromocyclization and bromination reactions of unsaturated carboxylic acids, alkenes and indoles with pendant nucleophiles, and arenes in heptane, where adequate suppression of the background reactions was observed, to yield bromolactones, bromomethyl-substituted heterocycles, fused indolines such as pyrroloindolines, and aryl bromides. The key feature of the active site is the alkoxy group attached to the sulfonamide moiety, which facilitates the acceptance as well as the delivery of bromonium species from the bromine source to the substrates. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to bromolactone aryl bromide chemoselective preparation, methoxybutanesulfonamide catalyst bromosuccinimide mediated bromocyclization bromination, chemoselective bromination bromocyclization methoxysulfonamide catalyst bromosuccinimide and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem