Tag: 100-200

On July 19, 2021, Xin, Hai-Long; Rao, Xiaofeng; Ishitani, Haruro; Kobayashi, Shu published an article.HPLC of Formula: 321-28-8 The title of the article was Sequential Continuous-Flow Synthesis of 3-Aryl Benzofuranones. And the article contained the following:

A sequential continuous-flow system to produce 3-aryl benzofuranones was developed. Starting from 2,4-di-tert-butylphenol and glyoxylic acid monohydrate, both the initial cyclocondensation and the subsequent Friedel-Crafts alkylation were catalyzed by the same heterogeneous catalyst, Amberlyst-15H. The catalyst has a promising life-time for these two steps, and it was able to be recovered and reused for several runs without deactivation. By using the established flow system, 5,7-di-tert-butyl-3-(3,4-dimethylphenyl)-3H-benzofuran-2-one (Irganox HP-136), which is a com. antioxidant, was prepared in 88% two-step yield. Reactions with various aromatic compounds proceeded well under flow conditions to afford 3-aryl benzo-furanone derivatives in high yields with good functional group compatibility. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).HPLC of Formula: 321-28-8

The Article related to tert butylphenol glyoxylic acid cyclocondensation friedel crafts amberlyst, hydroxy benzofuranone arene sequential continuous flow, aryl benzofuranone preparation, 3-aryl benzofuranones, amberlyst-15h, continuous-flow, heterogeneous catalyst, irganox hp-136 and other aspects.HPLC of Formula: 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On January 31, 2022, Kiliclar, Huseyin Cem; Gencosman, Emirhan; Yagci, Yusuf published an article.Formula: C8H10O2 The title of the article was Visible light induced conventional step-growth and chain-growth condensation polymerizations by electrophilic aromatic substitution. And the article contained the following:

A novel visible light induced step-growth polymerization by electrophilic aromatic substitution between photochem. generated carbocations and dimethoxybenzene nucleophile is described. Conventional step-growth polymerization and chain-growth condensation polymerization (CCP) mechanisms are presented. It is found that by changing the molar ratios of the monomers slightly, the CCP mechanism becomes operative and relatively higher mol. weight polymers are obtained because of the higher reactivity of the end groups of the intermediates and oligomers than that of the monomers. The possibility of grafting onto polymers containing epoxide at their side chains by photoinduced chain end activation of poly(dimethoxyphenylene methylene) is demonstrated. This study is expected to promote potential applications of the combination of photoinduced electron transfer reactions and CCP in macromol. synthesis and material science. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Formula: C8H10O2

The Article related to visible light step chain growth condensation polymerization electrophilic aromatic, dimethoxybenzene, chain-growth condensation polymerization, electrophilic aromatic substitution, photopolymerization, polyphenylenemethylene, step-growth polymerization and other aspects.Formula: C8H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Taglang, Celine; Martinez-Prieto, Luis Miguel; del Rosal, Iker; Maron, Laurent; Poteau, Romuald; Philippot, Karine; Chaudret, Bruno; Perato, Serge; Sam Lone, Anais; Puente, Celine; Dugave, Christophe; Rousseau, Bernard; Pieters, Gregory published an article in 2015, the title of the article was Enantiospecific C-H activation using ruthenium nanocatalysts.Safety of (S)-1-Methoxypropan-2-amine hydrochloride And the article contains the following content:

The activation of C-H bonds has revolutionized modern synthetic chem. However, no general strategy for enantiospecific C-H activation has been developed to date. We herein report an enantiospecific C-H activation reaction followed by deuterium incorporation at stereogenic centers. Mechanistic studies suggest that the selectivity for the α-position of the directing heteroatom results from a four-membered dimetallacycle as the key intermediate. This work paves the way to novel mol. chem. on nanoparticles. The experimental process involved the reaction of (S)-1-Methoxypropan-2-amine hydrochloride(cas: 1162054-86-5).Safety of (S)-1-Methoxypropan-2-amine hydrochloride

The Article related to enantiospecific ch activation reaction deuterium incorporation ruthenium nanocatalyst nanoparticle, langmuir hinshelwood deuteration mechanism ab initio dimetallacycle, ch activation, ab initio calculations, deuterium, isotopic labeling, nanoparticles and other aspects.Safety of (S)-1-Methoxypropan-2-amine hydrochloride

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Minoda, Masahiko; Otsubo, Tomomi; Yamamoto, Yohei; Zhao, Jianxin; Honda, Yoshitomo; Tanaka, Tomonari; Motoyanagi, Jin published an article in 2019, the title of the article was The First Synthesis of Periodic and Alternating Glycopolymers by RAFT Polymerization: A Novel Synthetic Pathway for Glycosaminoglycan Mimics.Electric Literature of 929-37-3 And the article contains the following content:

This study concerned the controlled synthesis of periodic glycopolymers by reversible addition-fragmentation chain transfer (RAFT) copolymerization To this end, maltose- and lactose-substituted vinyl ethers (MalVE and LacVE, resp.) and maltose-substituted maleimide (MalMI) were newly synthesized. RAFT copolymerization of MalVE and Et maleimide (EtMI) (monomer feed ratio: MalVE:EtMI = 1:1) afforded periodic glycopolymers (poly(MalVE-co-EtMI)) consisting of major parts of alternating structure (-(MalVE-EtMI)n-) and a small part of consecutive sequences of EtMI (-EtMI-EtMI-). Occurrence of the latter sequences was caused by the homopolymerizability of maleimide under the present polymerization condition, and the formation of the consecutive sequences of EtMI was successfully suppressed by varying the monomer feed ratio. RAFT copolymerization of LacVE and EtMI was also found to proceed and similarly yielded periodic glycopolymers (poly(LacVE-co-EtMI)). Moreover, RAFT copolymerization of LacVE and MalMI (monomer feed ratio: LacVE:MalMI = 1:1) was performed to give copolymers (poly(LacVE-co-MalMI)) having composition ratio of LacVE/MalMI ≈ 36/64. The resultant periodic glycopolymers poly(MalVE-co-EtMI) and poly(LacVE-co-EtMI) were subjected to lectin binding assay using Con A and peanut agglutinin, exhibiting the glycocluster effect. Moreover, these glycopolymers obtained from the copolymerization of VE and MI were found to be non-cytotoxic. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Electric Literature of 929-37-3

The Article related to glycosaminoglycan mimics glycopolymer raft polymerization, cuaac click reaction, raft copolymerization, alternating glycopolymer, carbohydrate-substituted maleimide, carbohydrate-substituted vinyl ether, glycosaminoglycan mimics, periodic glycopolymer and other aspects.Electric Literature of 929-37-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 29, 1991, Dubroeucq, Marie Christine; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the patent was Preparation of 2-(phenylacetyl)-7,7-diphenylperhydroisoindol-4-ones and analogs as substance P antagonists. And the patent contained the following:

Title compounds [I; R = H; RR = bond; R4 = Ph, halophenyl, tolyl; R5 = C(:X)CHR1R2; R1 = (un)substituted Ph, alkyl, alkoxy, etc.; R2 = H, halo, OH, alkyl, etc.; X = O, S, NR3; R3 = H, dialkylamino, (un)substituted alkyl] were prepared Thus, 4,4-diphenyl-2-cyclohexenone was cyclocondensed with PhCH2N(CH2OBu)CH2SiMe3 to give, after debenzylation and optical resolution, (3aR, 7aR)-I (R = H, R4 = Ph) (II; R5 = H) which was condensed with 2-(Me2N)C6H4CH2CO2H to give II [R5 = COCH2C6H4(NMe2)-2]. The latter gave 80% inhibition of behavioral effects induced by substance P at 10 mg/kg s.c. I drug formulations were prepared The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to isoindolone acyldiphenylperhydro substance p antagonist, analgesic acyldiphenylperhydroisoindolone preparation, antiinflammatory acyldiphenylperhydroisoindolone preparation, antiallergic acyldiphenylperhydroisoindolone preparation, nervous system agent acyldiphenylperhydroisoindolone preparation and other aspects.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 4, 2016, Lansakara, Ashabha I.; Mariappan, S. V. Santhana; Pigge, F. Christopher published an article.Synthetic Route of 929-37-3 The title of the article was Alkylidene Dihydropyridines As Synthetic Intermediates: Model Studies toward the Synthesis of the Bis(piperidine) Alkaloid Xestoproxamine C. And the article contained the following:

Results of model studies demonstrating a stereoselective synthetic route to tricyclic analogs of the bis(piperidine) alkaloid xestoproxamine C are presented. Dearomatization of a tricyclic pyridine derivative to afford an alkylidene dihydropyridine (anhydrobase) intermediate followed by catalytic heterogeneous hydrogenation was used to install the correct relative stereochem. about the bis(piperidine) ring system. Other key features of these model studies include development of an efficient ring-closing metathesis procedure to prepare macrocyclic derivatives of 3,4-disubstituted pyridines, intramol. cyclizations of alkylidene dihydropyridines to establish pyridine-substituted pyrrolidines and piperidines, successful homologation of pyridine-4-carboxaldehydes using formaldehyde di-Me thioacetal monoxide (FAMSO), and application of B-alkyl Suzuki coupling to assemble substituted pyridines. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Synthetic Route of 929-37-3

The Article related to xestoproxamine c analog stereoselective synthesis alkylidenedihydropyridine intermediate model study, dearomatization tricyclic pyridine derivative alkylidenedihydropyridine, stereoselective hydrogenation alkylidenedihydropyridine, ring closing macrocyclization xestoproxamine c analog synthesis and other aspects.Synthetic Route of 929-37-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 30, 2021, Zhang, Ying-Qi; Chen, Yang-Bo; Liu, Ji-Ren; Wu, Shao-Qi; Fan, Xin-Yang; Zhang, Zhi-Xin; Hong, Xin; Ye, Long-Wu published an article.Reference of 2-Methoxynaphthalene The title of the article was Asymmetric dearomatization catalysed by chiral Bronsted acids via activation of ynamides. And the article contained the following:

The chiral Bronsted acids enable the catalytic asym. dearomatization reactions of naphthols- phenols- RCCN(R1)R2 (R = 2-(4-hydroxynaphthalen-1-yl)benzen-1-yl, 2-(4-hydroxy-1,4,5,6,7,8-hexahydronaphthalen-1-yl)benzen-1-yl, 2-(2-hydroxyphenyl)benzen-1-yl, etc.; R1 = Ms, Ts, Bs, etc.; R2 = Ph, naphthalen-2-yl, n-Bu, etc.) and pyrrole-ynamides R3(CH2)2NCC(R1)R2 (R3 = 2,5-dimethyl-1H-pyrrol-1-yl, 2-methyl-5-(thiophen-3-yl)-1H-pyrrol-1-yl, 2-methyl-5-phenyl-1H-pyrrol-1-yl, etc.) by the direct activation of alkynes. This method leads to the practical and atom-economic construction of various valuable spirocyclic enones I (R4 = H, 6-F, benzene-1,2-bis(yl), 5-Cl, etc.) and II, 2H-pyrroles III (R5 = Me, Ph, thiophen-2-yl, etc.; R6 = Me, Et) that bear a chiral quaternary carbon stereocenter in generally good-to-excellent yields with excellent chemo-, regio- and enantioselectivities. The activation mode of chiral Bronsted acid catalysis revealed in this study is expected to be of broad utility in catalytic asym. reactions that involve ynamides and the related heteroatom-substituted alkynes. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Reference of 2-Methoxynaphthalene

The Article related to spirocyclic enone preparation regioselective chemoselective diastereoselective, naphthol ynamide preparation asym dearomatization bronsted acid catalyst, phenol ynamide preparation asym dearomatization bronsted acid catalyst, pyrrole preparation regioselective chemoselective diastereoselective and other aspects.Reference of 2-Methoxynaphthalene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 19, 2021, Zhao, Lanxiao; Shi, Xianghui; Cheng, Jianhua published an article.Name: 2-Methoxynaphthalene The title of the article was Calcium-Catalyzed Dehydrogenative Silylation of Aromatic Ethers with Hydrosilane. And the article contained the following:

The catalytic regioselective C-H silylation of a wide range of alkoxy-substituted benzene derivatives with primary hydrosilane was achieved using scorpionate-supported Ca benzyl complex [(TpAd,iPr)Ca(p-CH2C6H4Me)(THP)] (1) (TpAd,iPr = hydrotris(3-adamantyl-5-isopropylpyrazolyl)borate, THP = tetrahydropyran) as the precatalyst. This protocol offers an atom-efficient and straightforward method for the synthesis of a variety of silyl-substituted aromatic ether derivatives without a H acceptor and free of transition metal. Ca anisyl complexes [(TpAd,iPr)Ca(o-MeO-m-Br-C6H3)] (5) and [(TpAd,iPr)Ca(o-Me-OCH2C6H4)] (6), proposed as the catalytic reaction intermediates, were isolated and structurally characterized. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Name: 2-Methoxynaphthalene

The Article related to calcium benzyl complex catalyzed dehydrogenative silylation aromatic ether hydrosilane, scorpionate supported calcium benzyl ether complex preparation crystal structure, mol structure scorpionate supported calcium benzyl ether complex, silyl substituted aromatic ether derivative preparation and other aspects.Name: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 19, 2021, Zhao, Lanxiao; Shi, Xianghui; Cheng, Jianhua published an article.Application of 578-58-5 The title of the article was Calcium-Catalyzed Dehydrogenative Silylation of Aromatic Ethers with Hydrosilane. And the article contained the following:

The catalytic regioselective C-H silylation of a wide range of alkoxy-substituted benzene derivatives with primary hydrosilane was achieved using scorpionate-supported Ca benzyl complex [(TpAd,iPr)Ca(p-CH2C6H4Me)(THP)] (1) (TpAd,iPr = hydrotris(3-adamantyl-5-isopropylpyrazolyl)borate, THP = tetrahydropyran) as the precatalyst. This protocol offers an atom-efficient and straightforward method for the synthesis of a variety of silyl-substituted aromatic ether derivatives without a H acceptor and free of transition metal. Ca anisyl complexes [(TpAd,iPr)Ca(o-MeO-m-Br-C6H3)] (5) and [(TpAd,iPr)Ca(o-Me-OCH2C6H4)] (6), proposed as the catalytic reaction intermediates, were isolated and structurally characterized. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application of 578-58-5

The Article related to calcium benzyl complex catalyzed dehydrogenative silylation aromatic ether hydrosilane, scorpionate supported calcium benzyl ether complex preparation crystal structure, mol structure scorpionate supported calcium benzyl ether complex, silyl substituted aromatic ether derivative preparation and other aspects.Application of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 19, 2021, Zhao, Lanxiao; Shi, Xianghui; Cheng, Jianhua published an article.Recommanded Product: 150-78-7 The title of the article was Calcium-Catalyzed Dehydrogenative Silylation of Aromatic Ethers with Hydrosilane. And the article contained the following:

The catalytic regioselective C-H silylation of a wide range of alkoxy-substituted benzene derivatives with primary hydrosilane was achieved using scorpionate-supported Ca benzyl complex [(TpAd,iPr)Ca(p-CH2C6H4Me)(THP)] (1) (TpAd,iPr = hydrotris(3-adamantyl-5-isopropylpyrazolyl)borate, THP = tetrahydropyran) as the precatalyst. This protocol offers an atom-efficient and straightforward method for the synthesis of a variety of silyl-substituted aromatic ether derivatives without a H acceptor and free of transition metal. Ca anisyl complexes [(TpAd,iPr)Ca(o-MeO-m-Br-C6H3)] (5) and [(TpAd,iPr)Ca(o-Me-OCH2C6H4)] (6), proposed as the catalytic reaction intermediates, were isolated and structurally characterized. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Recommanded Product: 150-78-7

The Article related to calcium benzyl complex catalyzed dehydrogenative silylation aromatic ether hydrosilane, scorpionate supported calcium benzyl ether complex preparation crystal structure, mol structure scorpionate supported calcium benzyl ether complex, silyl substituted aromatic ether derivative preparation and other aspects.Recommanded Product: 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem