Tag: 100-200

Recommanded Product: 2-(Benzyloxy)acetaldehydeIn 2021 ,《Photoredox-catalyzed aminofluorosulfonylation of unactivated olefins》 was published in Chemical Science. The article was written by Zhong, Tao; Yi, Ji-Tao; Chen, Zhi-Da; Zhuang, Quan-Can; Li, Yong-Zhao; Lu, Gui; Weng, Jiang. The article contains the following contents:

The first three-component aminofluorosulfonylation of unactivated olefins, e.g., cyclohex-2-en-1-yl N-(4-chlorophenyl)carbamate by merging photoredox-catalyzed proton-coupled electron transfer (PCET) activation with radical relay processes has been described. Various aliphatic sulfonyl fluorides featuring a privileged 5-membered heterocyclic core compounds, e.g., I have been efficiently afforded under mild conditions with good functional group tolerance. The synthetic potential of the sulfonyl fluoride products has been examined by diverse transformations including SuFEx reactions and transition metal-catalyzed cross-coupling reactions. Mechanistic studies demonstrate that amidyl radicals, alkyl radicals and sulfonyl radicals are involved in this difunctionalization transformation. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Recommanded Product: 2-(Benzyloxy)acetaldehyde)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Recommanded Product: 2-(Benzyloxy)acetaldehyde

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC of Formula: 673-22-3In 2022 ,《Recyclable palladium-catalyzed cyclocarbonylation between benzyl chlorides and salicylic aldehydes towards coumarins》 was published in Molecular Catalysis. The article was written by Zhou, Yan; Zhou, Zebiao; Liu, Siqi; Cai, Mingzhong. The article contains the following contents:

A novel and practical route to coumarin derivatives was developed via the heterogeneous Pd-catalyzed carbonylative reaction and subsequent intramol. condensation process starting from com. easily available benzyl chlorides and salicylic aldehydes. Reactions were performed in the existence of 2 mol% of an SBA-15-immobilized bidentate phosphine palladium complex [SBA-15-P,P-PdCl2] in dioxane at 110°C with Et3N as base under 10 bar of CO to afford a wide range of coumarin derivatives mostly with good to high yields. Importantly, this new heterogenized palladium complex was easy to recover via filtration of the reaction mixture, and was recyclable up to 8 times without apparent drop in its catalytic performance. After reading the article, we found that the author used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3HPLC of Formula: 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.HPLC of Formula: 673-22-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Shao, Huihui; Zhao, Yao; Wang, Shuangqiang; Chen, Rizhi; Zhou, Jianrong Steve; Wu, Xiaojin published an article in Organic Letters. The title of the article was 《Reductive-Delay Heck 1,1-Diarylation of Terminal Alkenes》.Reference of 1-Bromo-3-methoxybenzene The author mentioned the following in the article:

Synthesis of 5,5-diaryl-N-(quinolin-8-yl)pentanamides such as I [R = H, Me, Ph, etc.; R1 = Ph, 4-t-BuC6H4, 4-F3CC6H4, etc.; R2 = Ph, 3-MeOC6H4, 1-naphthyl, etc.] via Pd-catalyzed, chemo- and regiocontrollable 1,1-diarylation of unactivated aliphatic alkenes with two aryl bromides was done. Under the cationic reductive-delay Heck pathway, the first aryl insertion was followed by β-H elimination, while the second aryl insertion was terminated by C-H bond formation. The results came from multiple reactions, including the reaction of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Reference of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Reference of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Anand, Ashish; Sindogi, Kishorkumar; Dixit, Sheshagiri R.; Shetty, Richa P.; Pujar, Gurubasavaraj V.; Kulkarni, Manohar V.; Guru Row, Tayur N. published an article in ChemistrySelect. The title of the article was 《Comparative Investigation on the Crystal Structures, Hirshfeld Surface Analysis, Antitubercular Assays, and Molecular Docking of Regioisomeric 1,2,3-Triazoles》.HPLC of Formula: 150-19-6 The author mentioned the following in the article:

1,2,3-Triazole system is readily obtained by the click reaction in a facile and regioselective way. Regioselectivity is introduced under Copper(CuAAC), and Ruthenium(RuAAC) catalyzed azide-alkyne cycloaddition reaction furnishing 1,4 and 1,5-disubstituted triazoles, resp. These two regioisomeric systems offer discrete physicochem. and medicinal properties based on crucial binding interactions and biocompatibility with the biol. targets. In this regard, a comparative investigation on the coumarin-linked regioisomeric 1,2,3-triazoles via its crystal structure, Hirshfeld surface anal., and antitubercular assays and mol. docking are reported. It sheds light on the variation of in vitro antitubercular efficacy against Mycobacterium tuberculosis H37Rv followed by mol. docking studies that justify the prominent interactions at the binding site. Further, solid-state and Hirshfeld surface anal. provided significant crystallog. insights on the critical intermol. interactions that dictate the crystal packing in these systems. Thus structure-property correlation for these regioisomeric systems can open new avenues in drug design and discovery. The results came from multiple reactions, including the reaction of m-Methoxyphenol(cas: 150-19-6HPLC of Formula: 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneHPLC of Formula: 150-19-6

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Heberle, Martin; Legendre, Sarah; Wannenmacher, Nick; Weber, Manuel; Frey, Wolfgang; Peters, Rene published an article in 2022. The article was titled 《Bispalladacycle Catalyzed Nucleophilic Enantioselective Allylation of Aldehydes by Allylstannanes》, and you may find the article in ChemCatChem.Product Details of 60656-87-3 The information in the text is summarized as follows:

The first palladium catalysts capable of controlling asym. nucleophilic allylations of aldehydes with allyltributyltin was reported. TONs up to 620 were achieved, which is significantly higher than for any other reported catalyst. The method also tolerated electronically and sterically unfavorable substrates. It was showed that transmetallation occurred, favoring an η1-allyl coordination mode with the bispalladacycles. In contrast, for the corresponding monopalladacycle an unproductive η3 coordination was dominant. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Product Details of 60656-87-3)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Product Details of 60656-87-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhu, Da-Liang; Jiang, Shan; Wu, Qi; Wang, Hao; Li, Hai-Yan; Li, Hong-Xi published an article in 2021. The article was titled 《Nickel-Catalyzed Etherification of Phenols and Aryl Halides through Visible-Light-Induced Energy Transfer》, and you may find the article in Organic Letters.Safety of m-Methoxyphenol The information in the text is summarized as follows:

A visible-light-initiated, nickel-catalyzed O-arylation of phenols with arylhalides using t-BuNH(i-Pr) as the base and thioxanthen-9-one as the photosensitizer under visible light was reported. This photocoupling exhibited a broad substrate scope. In the experiment, the researchers used many compounds, for example, m-Methoxyphenol(cas: 150-19-6Safety of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Safety of m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lin, Tingzhi; Qian, Pengcheng; Wang, Yan-En; Ou, Mingjie; Jiang, Long; Zhu, Chen; Xu, Yuchuan; Xiong, Dan; Mao, Jianyou published an article in 2021. The article was titled 《Palladium-Catalyzed Direct Arylation of 2-Pyridylmethyl Silanes with Aryl Bromides》, and you may find the article in Organic Letters.Formula: C7H7BrO The information in the text is summarized as follows:

The first palladium-catalyzed direct arylation of 2-pyridylmethyl silanes with aryl bromides to generate a diverse array of aryl(2-pyridyl)-Me silane derivatives has been developed. This protocol facilitates access to various kinds of heterocycle-containing silanes in good to excellent yields (40 examples, 66-97% yield) with good functional group tolerance. The scalability of this transformation is demonstrated. In the experiment, the researchers used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Formula: C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Formula: C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jung, Woo-Ok; Yoo, Minjin; Migliozzi, Madyson M.; Zbieg, Jason R.; Stivala, Craig E.; Krische, Michael J. published an article in 2022. The article was titled 《Regio- and Enantioselective Iridium-Catalyzed Amination of Alkyl-Substituted Allylic Acetates with Secondary Amines》, and you may find the article in Organic Letters.Computed Properties of C9H10O2 The information in the text is summarized as follows:

Robust air-stable cyclometalated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were observed despite the formation of more highly substituted C-N bonds. The experimental part of the paper was very detailed, including the reaction process of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Computed Properties of C9H10O2)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Computed Properties of C9H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Zhenhao; Sabat, Nazarii; Frison, Gilles; Marinetti, Angela; Guinchard, Xavier published an article in 2022. The article was titled 《Enantioselective Au(I)-Catalyzed Multicomponent Annulations via Tethered Counterion-Directed Catalysis》, and you may find the article in ACS Catalysis.Category: ethers-buliding-blocks The information in the text is summarized as follows:

Gold(I) complexes of a chiral phosphoric acid-functionalized phosphine of the CPA-Phos series enable the enantioselective multicomponent reactions between aldehydes, hydroxylamines, and cyclic yne-enones, leading to 3,4-dihydro-1H-furo[3,4-d][1,2]oxazines. This represents a rare example of a highly enantioselective multicomponent reaction in gold(I) catalysis. The reactions proceed at a low catalyst loading and provide high yields, total diastereoselectivity, and enantiomeric excesses up to 99%. Silver-free conditions was applied. The method had a very broad scope as it applies to both aliphatic and aromatic aldehydes and hydroxylamines, to a variety of cyclic yne-enones, and to yne-enone-derived oximes. DFT calculations complement this study to enlighten reactivity issues and mechanistic pathways. The experimental part of the paper was very detailed, including the reaction process of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Category: ethers-buliding-blocks)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yu, Weiwei; Hu, Zhiru; Fu, Xinyu; Li, Yanchun; Su, Junfeng; Yang, Ting; Li, Songrui; Song, Zhiguang; Feng, Guodong published an article in 2021. The article was titled 《Phenanthroline derivative fluorescent probe for rapid and sensitive detection of silver(I)》, and you may find the article in Analytical Sciences.Quality Control of 2-Methoxybenzaldehyde The information in the text is summarized as follows:

In the present work, a phenanthroline derivative (2-(2-methoxyphenyl)-4-phenyl-1,10-phenanthroline, MPP), as a fluorescent probe, was synthesized to realize a rapid, simple and sensitive detection of silver(I). The detection conditions of Ag+ were optimized. This fluorescent probe has the advantages of a fast reaction time, a wide pH applicable range, and a low detection limit, exhibiting a good linear response between the fluorescence intensity and the concentration in the range of 0.05 – 1.5 μmol/L for Ag+. The detection limit is as low as 3.38 x 10-8 mol/L (S/N = 3). This probe had been used to detect Ag+ in real samples, and the recovery efficiency of spiked Ag+ had been also tested. The recovery efficiency is satisfactory, ranging from 92.0 to 105.4%. Therefore, this fluorescent probe should provide a new choice for the quant. detection of silver ions in environmental water samples. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4Quality Control of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Quality Control of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem