Tag: 100-200

In 2019,Research on Chemical Intermediates included an article by Poonam; Singh, Ram. Reference of 2-Methoxybenzaldehyde. The article was titled 《Facile one-pot synthesis of 5-amino-1H-pyrazole-4-carbonitriles using alumina-silica-supported MnO2 as recyclable catalyst in water》. The information in the text is summarized as follows:

MnO2 supported on Al2O3/SiO2 was prepared as a recyclable catalyst for the multicomponent cyclocondensation of aryl aldehydes, malononitrile, and phenylhydrazine in water containing sodium dodecylbenzenesulfonate to yield aminoarylphenylpyrazolecarbonitriles I in 86-96% yields. The catalyst was used five times with little decrease in product yield in the first three reactions. The experimental process involved the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Reference of 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Reference of 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2012,Advanced Functional Materials included an article by Yan, Mei; Ge, Lei; Gao, Weiqiang; Yu, Jinghua; Song, Xianrang; Ge, Shenguang; Jia, Zhiyong; Chu, Chengchao. Recommanded Product: 74029-40-6. The article was titled 《Electrogenerated Chemiluminescence from a Phenyleneethynylene Derivative and its Ultrasensitive Immunosensing Application Using a Nanotubular Mesoporous Pt-Ag Alloy for Signal Amplification》. The information in the text is summarized as follows:

Electrogenerated chemiluminescence (ECL) of a novel phenyleneethynylene derivative [4,4′-(2,5-dimethoxy-1,4-phenylene)bis(ethyne-2,1-diyl) dibenzoic acid; P-acid] possessing carboxylic acid groups at the para positions in aqueous solutions and its first immunosensing application were studied. Nanotubular mesoporous Pt-Ag alloy nanoparticles are first used to fabricate the ECL immunosensor as a signal amplification carrier. Absorption, photoluminescence, cyclic voltammetry, SEM, TEM, and electrochem. impedance spectroscopy were used as powerful tools to characterize P-acid, Pt-Ag alloy nanoparticles, and the fabrication process of the immunosensor. P-acid exhibits two ECL peaks at -1.07 (ECL-1) and 0.64 (ECL-2) V in air-saturated pH 7.4, 0.1 M PBS containing 0.1 M KCl during the cyclic sweep between 1.51 and -2.67 V at 0.1 V s-1; the ECL mechanism of these two ECL peaks is demonstrated. The electron-transfer reaction between electrochem. oxidized P-acid and tri-n-propylamine (TPrA) radical cation is also demonstrated to produce high ECL emissions and used to develop an ultrasensitive ECL immunosensor. In addition, a Pt-Ag alloy nanoparticles amplification carrier for protein ECL anal. is applied for improvement of the detection sensitivity. Thus, this ECL immunosensor exhibits high sensitivity, good reproducibility, rapid response, and long-term stability. The results came from multiple reactions, including the reaction of 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Recommanded Product: 74029-40-6)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however. Recommanded Product: 74029-40-6

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Ether – Wikipedia,
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《The efficient synthesis of D-xylulose and formal synthesis of Syringolide 1》 was written by Kalagara, Sudhakar; Orozco, Gabriel; Mito, Shizue. Recommanded Product: 60656-87-3This research focused onxylulose stereoselective hydroxylation hydroxyacetone ethylene glycol syringolide Wittig. The article conveys some information:

Wittig reaction and asym. dihydroxylation were used as the key steps in the synthesis of D-xylulose, a com. available but costly carbohydrate. The effects of protecting groups and reactions conditions on asym. dihydroxylation are demonstrated. Optically pure D-xylulose was obtained after 4-6 steps from readily available hydroxyacetone and ethylene glycol. The method also involves some other valuable intermediates along the synthesis. Those intermediates were applied in the formal synthesis of Syringolides. A key precursor butenolide to Syringolide 1, the first non-protein specific elicitors of plant hypersensitive response, was obtained after 3 steps from the intermediate (8-10 steps from hydroxyacetone and ethylene glycol). In the experiment, the researchers used many compounds, for example, 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Recommanded Product: 60656-87-3)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Recommanded Product: 60656-87-3

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Ether – Wikipedia,
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《Synthesis and optical properties of a novel sugar coated poly(p-phenyleneethynylene) effectively quenched by concanavalin A》 was written by Tsakama, Madalitso; Shang, Yuting; He, Yonghuang; Fan, Bei; Wang, Fengzhong; Chen, Weihua; Dai, Xiaofeng. Name: 1,4-Diethynyl-2,5-dimethoxybenzene And the article was included in Tetrahedron Letters on April 20 ,2016. The article conveys some information:

The synthesis of a novel sugar coated poly(p-phenyleneethynylene) (PPE) via Pd-catalyzed Sonogashira reaction and its subsequent interaction with Con A are described. UV-visible and fluorescence spectra were employed to study the response of the polymer toward various concentrations of Con A. The polymer showed a green fluorescence which can be quenched by Con A due to complex formation at ground state. The protocols reported herein provide intermediate products that can be converted into useful sensing elements from cheap and com. available starting materials, in a few number of steps. In the part of experimental materials, we found many familiar compounds, such as 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Name: 1,4-Diethynyl-2,5-dimethoxybenzene)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Name: 1,4-Diethynyl-2,5-dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Russian Chemical Bulletin included an article by Vasil’ev, L. S.; Baranin, S. V.; Dmitrenok, A. S.; Zavarzin, I. V.. Related Products of 4637-24-5. The article was titled 《A new approach to CF3-containing 3,4-dihydroquinazolin-2(1H)-ones》. The information in the text is summarized as follows:

A new approach to CF3-containing 3,4-dihydroquinazolin-2(1H)-ones based on the condensation of 5-acetyl-6-methyl-1-phenyl-4-trifluoromethylpyrimidin-2(1H)-one with DMF di-Me acetal was suggested. After reading the article, we found that the author used N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Related Products of 4637-24-5)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Related Products of 4637-24-5

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Ether – Wikipedia,
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Safety of 1,4-Diethynyl-2,5-dimethoxybenzeneOn May 21, 2013 ,《Conjugated Porous Polymers For TNT Vapor Detection》 appeared in ACS Macro Letters. The author of the article were Novotney, Jennifer L.; Dichtel, William R.. The article conveys some information:

A conjugated porous polymer (CPP) that exhibits fluorescence quenching when exposed to TNT vapor was synthesized via a Sonaogashira cross-coupling reaction. Two polymerization solvents, DMF and PhMe, and two activation procedures, evacuation and lyophilization, were evaluated to optimize the response of the CPP to TNT vapor. Key differences in surface area and absorption were seen as a function of polymerization solvent and activation procedure. The polymer synthesized in DMF and activated by lyophilization had the highest surface area and the strongest response to TNT vapor. This paper demonstrates the importance of growth and activation conditions in optimizing the porosity and sensing performance of CPPs. In the experiment, the researchers used many compounds, for example, 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Safety of 1,4-Diethynyl-2,5-dimethoxybenzene)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Safety of 1,4-Diethynyl-2,5-dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: (3-Methoxy-2-methylphenyl)methanolOn March 11, 2000, Peixoto, Christophe; Laurin, Patrick; Klich, Michel; Dupuis-Hamelin, Claudine; Mauvais, Pascale; Lassaigne, Patrice; Bonnefoy, Alain; Musicki, Branislav published an article in Tetrahedron Letters. The article was 《Synthesis of isothiochroman 2,2-dioxide and 1,2-benzoxathiin 2,2-dioxide gyrase B inhibitors》. The article mentions the following:

The design, synthesis, and in-vitro biol. evaluation of isothiochroman 2,2-dioxide and 1,2-benzoxathiin 2,2-dioxide analogs of coumarin inhibitors of gyrase B are described. Compared to coumarin derivatives, compounds of the 1,2-benzoxathiin 2,2-dioxide series display improved inhibitory potency in neg. supercoiling of relaxed DNA gyrase. In the experiment, the researchers used many compounds, for example, (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1Recommanded Product: (3-Methoxy-2-methylphenyl)methanol)

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Recommanded Product: (3-Methoxy-2-methylphenyl)methanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Washable colorimetric nanofiber nonwoven for ammonia gas detection》 was written by Oh, Hyun Ju; Yeang, Byeong Jin; Park, Young Ki; Choi, Hyun Jung; Kim, Jong H.; Kang, Young Sik; Bae, Younghwan; Kim, Jung Yeon; Lim, Seung Ju; Lee, Woosung; Hahm, Wan-Gyu. Synthetic Route of C8H8O3This research focused onwashable colorimetric nanofiber nonwoven ammonia gas detection; ammonia gas; colorimetric nanofiber sensor; gas detection; meta-aramid nanofiber. The article conveys some information:

The colorimetric sensor is a facile, cost-effective, and non-power-operated green energy material for gas detection. In this study, the colorimetric sensing property of a meta-aramid/dye 3 nanofiber sensor for ammonia (NH3) gas detection was investigated. This colorimetric sensor was prepared using various dye 3 concentrations via electrospinning. Morphol., thermal, structural, and mech. analyses of the sensor were carried out by field-emission SEM, thermogravimetric anal., Fourier-transform IR spectroscopy, and a universal testing machine, resp. A homemade computer color matching machine connected with a gas flow device characterized the response of the meta-aramid/dye 3 nanofiber colorimetric sensor to various exposure levels of NH3 gas. From the results, we confirmed that this colorimetric green energy sensor could detect ammonia gas in the concentration of 1-10 ppm with a sensing response time of 10 s at room temperature After washing with laundry detergent for 30 min, the colorimetric sensors still exhibited sensing property and reversibility.2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Synthetic Route of C8H8O3) was used in this study.

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Synthetic Route of C8H8O3

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Ether – Wikipedia,
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Name: 2-MethoxybenzaldehydeIn 2021 ,《Three-Component Efficient Synthesis of 2-Amino-3-cyano-4H-pyrans Catalyzed by Diammonium Hydrogen Phosphate in Aqueous Media》 appeared in Current Organocatalysis. The author of the article were Taghva, Pardis H.; Kabirifard, Hassan. The article conveys some information:

A series of 2-amino-3-cyano-4H-pyrans I [R = 4-MeC6H4, 2-ClC6H4, 3,4-(MeO)2C6H3, etc.] was synthesized by one-pot three-component condensation reactions of aromatic aldehydes RCHO, malononitrile and Me acetoacetate using diammonium hydrogen phosphate (DAHP) in aqueous ethanol at room temperature in excellent yields. All obtained structures were confirmed by their m.ps., IR, 1H NMR, 1C NMR spectroscopy, and also elemental analyses for new derivatives The present method is straightforward, quick, and most efficient green protocol for the synthesis of 2-amino-3-cyano-4H-pyrans using highly inexpensive, easy to handle and nontoxic DAHP as an efficient catalyst in aqueous ethanol medium at room temperature The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Name: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Name: 2-Methoxybenzaldehyde

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Chen, Yin-Jun; Xu, Hui-Bei; Liu, Hao; Dong, Lin published an article in Organic Chemistry Frontiers. The title of the article was 《Highly-selective synthesis of functionalized spirobenzofuranones and diketones》.Reference of m-Methoxyphenol The author mentioned the following in the article:

A convenient and atom-economical rhodium(III)-catalyzed highly-selective hydroacylation for the synthesis of spirobenzofuranones and diketones was successfully developed. Ortho-hydroxyl-group-assisted aldehyde C-H cascade [4+1] annulation makes the formation of spiro compounds more efficient. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6Reference of m-Methoxyphenol) was used in this study.

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneReference of m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem