Tag: 100-200

Vankar, H. P.; Rana, V. A. published their research in Materials Today: Proceedings in 2021. The article was titled 《Density, viscosity and ultrasonic velocity study: Binary mixtures of 3-bromoanisole and methanol at different temperatures》.COA of Formula: C7H7BrO The article contains the following contents:

The values of d., viscosity and ultrasonic velocity at three different temperatures (303.15, 313.15 and 323.15 K) of the prepared binary mixture solutions with different compositions of 3-bromoanisole (3-BA) and methanol (MeOH) are exptl. determined and presented. Moreover, the excess values of molar volume, viscosity and ultrasonic velocity have been determined These determined excess properties are fitted to the Redlich-Kister equation. Deviations from the linearity are found in the exptl. measured parameters with variation in mixture composition and are interpreted in terms of mol. interaction. Moreover, thermodn. properties are evaluated to understand the dynamic behavior of the system. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0COA of Formula: C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.COA of Formula: C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Wu; Shu, Xiaomin; Huan, Leitao; Cheng, Buqing; Huo, Haohua published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Enantioselective β-C(sp3)-H arylation of amides via synergistic nickel and photoredox catalysis》.Reference of 1-Bromo-3-methoxybenzene The article contains the following contents:

An enantioselective benzylic β-C(sp3)-H arylation of amides RC(O)CH2CH2Ar (R = Me, phenylaminyl, [3-(trifluoromethyl)phenyl]aminyl, Ph, etc.; Ar = Ph, 4-methoxyphenyl, 3-chlorophenyl, etc.) via synergistic nickel and photoredox catalysis is reported. The C-H bond is activated by a bromine-radical-mediated C-H cleavage. This mild yet straightforward protocol provides arylation products (S)-RC(O)CH2CH(R1)Ar (R1 = 4-(trifluoromethyl)phenyl, 4-cyanophenyl, 3-bromophenyl, 1-benzothiophen-5-yl, etc.) in up to 96% yield and with up to 95% ee. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Reference of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Reference of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sands, Kai N.; Gelfand, Benjamin S.; Back, Thomas G. published their research in Journal of Organic Chemistry in 2021. The article was titled 《One-Pot Synthesis of Aryl Selenonic Acids and Some Unexpected Byproducts》.Electric Literature of C7H7BrO The article contains the following contents:

The synthesis of aryl selenonic acids was achieved from diverse aryl bromides via a one-pot method involving metalation, selenation, and oxidation with hydrogen peroxide followed by ion exchange to afford the pure products in 77-90% yield. An o-hydroxymethyl derivative was found to dehydrate readily, affording the first example of a cyclic selenonic ester, while two minor byproducts were isolated and shown by X-ray crystallog. to be mixed salts of aryl selenonic acids with either the corresponding aryl seleninic or selenious acid. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Electric Literature of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Electric Literature of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Miao, Shi-Xing; Wan, Lin-Xi; He, Zhen-Xiang; Zhou, Xian-Li; Li, Xiaohuan; Gao, Feng published their research in Journal of Natural Products in 2021. The article was titled 《Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer’s Disease Drug: Synthesis and Biological Evaluation of N-Aryl Huperzine A Analogues》.SDS of cas: 2398-37-0 The article contains the following contents:

The first systematic direct diversification of a complex natural product by metal-catalyzed N-H functionalization was carried out. A new series of N-(hetero)aryl analogs I (Ar = Ph, 2-naphthyl, 4-methylpyridin-2-yl, etc.) of the natural anti-Alzheimer’s disease drug huperzine A (HPA) was prepared via palladium-catalyzed Buchwald-Hartwig cross-coupling reactions of HPA with various aryl bromides ArBr in good yields. Most of the N-aryl-huperzine A (N-aryl-HPA) analogs showed good acetylcholinesterase (AChE) inhibitory activity in in vitro experiments Three arylated huperzine A analogs I (Ar = 4-FC6H4, 4-methoxy-2,6-dimethylphenyl, 5-methoxypyridin-2-yl) exhibited stronger anti-AChE activity than HPA. The 5-methoxy-2-pyridyl analog I (Ar = 5-methoxypyridin-2-yl) displayed the most potent AChE inhibition activity, with an IC50 value of 1.5μM, which was 7.6-fold more active than HPA. Compound I (Ar = 5-methoxypyridin-2-yl) also exhibited better neuroprotective activity for H2O2-induced damage in SH-SY5Y cells than HPA. Structure-activity relationship anal. suggested that the electron d. of the installed aromatic ring or heteroaromatic ring played a significant role in inducing the AChE inhibition activity. Overall, compound I (Ar = 5-methoxypyridin-2-yl) showed the advantages of easy synthesis, high potency and selectivity, and improved neuroprotection, making it a potential huperzine-type lead compound for Alzheimer’s disease drug development. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0SDS of cas: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.SDS of cas: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Palladium/N,N’-Disulfonyl Bisimidazoline-Catalyzed Enantioselective Addition of Arylboronic Acids to Cyclic N-Sulfonyl Ketimines》 was written by Li, Meng-Fan; Miao, An-Qi; Zhu, Hong-Yu; Wang, Rong; Hao, Wen-Juan; Tu, Shu-Jiang; Jiang, Bo. HPLC of Formula: 10365-98-7 And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

The combination of Pd(TFA)2 and an N,N’-disulfonyl bisimidazoline ligand shows high catalytic activity and excellent asym. induction in the addition of arylboronic acids to cyclic N-sulfonyl ketimines including benzo[d]isothiazole-1,1-dioxides, benzo[e][1,2,3]oxathiazine-2,2-dioxides, and 1,2,5-thiadiazole-1,1-dioxides, by which three types of chiral quaternary carbon-containing sultams with substantial substitution diversity were synthesized with high yields and excellent enantioselectivities (up to >99% ee). The current catalysis demonstrated a remarkable tolerance to oxygen and thus provided an operationally simple approach for constructing enantioenriched cyclic quaternary stereocenters. The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7HPLC of Formula: 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.HPLC of Formula: 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis, characterization and antibacterial effect of diarylmethylamine-based imines》 was published in Journal of Molecular Structure in 2020. These research results belong to Onur, Sultan; Kose, Muhammet; Kocer, Ferudun; Tumer, Ferhan. Safety of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:

Firstly, starting from benzoic acid, the diarylmethanone compound (4-methylphenyl)(phenyl)methanone was synthesized. The diarylmethanone (4-methylphenyl)(phenyl)methanone was converted to the corresponding oxime N-[(4-methylphenyl)(phenyl)methylidene]hydroxylamine and then reduced to the diarylmethylamine compd (4-methylphenyl)(phenyl)methanamine. Four different imine compounds2-OH-3-R1-4-R2C6H2CH=NCH(4-CH3C6H5)C6H4(R1 = H, OH, OMe; R2 = H, OH, OMe) were obtained from the condensation of the (4-methylphenyl)(phenyl)methanamine with four different salicylaldehyde 2-OH-3-R1-4-R2C6H2CHO. Antimicrobial activities against Gram (+) and Gram (-) microorganisms (Staphylococcus aureus, Bacillus cereus as the Gram (+); Escherichia coli and Salmonella typhimurium as the Gram (-); and Candida albicans as the fungi) were investigated. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis, Photophysics and Theoretical Calculation of (E)-2-(benzo[d] thiazol-2-yl)-3-(3-methoxyphenyl)acrylonitrile》 was published in Letters in Organic Chemistry in 2020. These research results belong to Wu, Pei-Chieh; Chen, Chih-Hsien. Recommanded Product: 2398-37-0 The article mentions the following:

A new type of luminogen with aggregation-induced-emission (AIE) behavior was designed and synthesized. The result of single-crystal x-ray structure showed a planar structure in which the dihedral angle between two aromatic rings is < 30o. Also, two different intermol. H bond interactions supported the stability of the crystal structure. After the formation of organic nanoparticles in poor solubility solvent, the emission intensity of the desired product was increased and the enhancement achieved was 14-fold. This new design of luminogen provided further understanding of the AIE mechanism. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Recommanded Product: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Recommanded Product: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Cp*Co(III)-Catalyzed o-Amidation of Benzaldehydes with Dioxazolones Using Transient Directing Group Strategy》 was published in Advanced Synthesis & Catalysis in 2020. These research results belong to Khan, Bhuttu; Dwivedi, Vikas; Sundararaju, Basker. Application of 135-02-4 The article mentions the following:

Transition metal-catalyzed ortho-selective C(sp2)-H amidation of weakly coordinating aldehydes remains limited to precious metals such as Ir, Rh, Ru, etc. Herein, a novel report on ortho-amidation of benzaldehydes employing user-friendly dioxazolones under cost-effective and air-stable Cp*Co(III) catalysis. This catalytic transformation involves transient directing group strategy to enhance the ligating capability of weakly chelating aldehydes.2-Methoxybenzaldehyde(cas: 135-02-4Application of 135-02-4) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Application of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Synthesis and characterization of a magnetic graphene oxide/Zn-Ni-Fe layered double hydroxide nanocomposite: An efficient mesoporous catalyst for the green preparation of biscoumarins》 were Zeynizadeh, Behzad; Gilanizadeh, Masumeh. And the article was published in New Journal of Chemistry in 2019. Related Products of 135-02-4 The author mentioned the following in the article:

In this study, a nanocomposite of Fe3O4@GO@Zn-Ni-Fe-layered double hydroxide was synthesized as a novel and efficient mesoporous magnetic nanocatalyst. The synthesis was carried out via the immobilization of Fe3O4 MNPs (magnetic nanoparticles) on graphene oxide and then the layering of Zn-Ni-Fe-layered double hydroxide moieties on the constituents of Fe3O4@GO. The magnetic graphene oxide/layered double hydroxide system was then characterized using SEM, EDX, FTIR, XRD, TEM and VSM analyses. The catalytic activity of the prepared composite system was further studied towards one-pot Knoevenagel-Michael reaction of aromatic aldehydes with 4-hydroxycoumarin in water. All reactions were carried out under reflux conditions, giving biscoumarin materials I (R = H, 4-Me, 2-MeO, 2,4-Cl2, 4-CHO, etc.) in 87-95% yields within 3-40 min. This method has noteworthy advantages in terms of mild reaction conditions, short reaction times, utilizing water as an environmental friendly solvent and applying a magnetically separable catalyst system. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Related Products of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Related Products of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ren, Huimin; Liu, Chao; Ding, Xu; Fu, Xianzhang; Wang, Hailong; Jiang, Jianzhuang published an article on February 1 ,2022. The article was titled 《High Fluorescence Porous Organic Cage for Sensing Divalent Palladium Ion and Encapsulating Fine Palladium Nanoparticles》, and you may find the article in Chinese Journal of Chemistry.Electric Literature of C12H10O2 The information in the text is summarized as follows:

Comprehensive Summary : Porous organic cages (POCs) as an innovative type of porous mol. materials enable multifunctional applications. Herein, a fluorescence POC (denoted as 1) has been constructed by means of 5,5′-((2,5-dimethoxy-1,4-phenylene)bis(ethyne-2,1-diyl))diisophthalaldehyde condensing with cyclohexanediamine enantiomer with the aid of trifluoroacetic acid. 1 exhibits the permanent void and prominent fluorescence with relative quantum yield of 73% confirmed by gas sorption and emission experiments, resp. Moreover, this organic cage is capable of sensing diavalent Pd2+ according to the fluorescence response to the addition of various metal ions. The dispersion of 1 in methanol containing palladium acetate was stirred at 25 °C and then 80 °C to reduce Pd2+ ions into nanoparticles (NPs), leading to the composite (Pd@1) composed of fine Pd NPs with the size of ca. 1.8 nm. The catalytic nature of Pd@1 over NaBH4 promoted the degeneration of nitrobenzene and congo red. This work introduces one new case of POCs with versatile properties and functions, including ion fluorescence recognition, fine Pd NPs stabilizer, and gas adsorption, enriching the family of POC-based materials. In the experiment, the researchers used 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Electric Literature of C12H10O2)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Electric Literature of C12H10O2 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem