Tag: 100-200

The author of 《Fluoroalkenylation of boronic acids via an oxidative Heck reaction》 were Lee, Da Seul; Cho, Eun Jin. And the article was published in Organic & Biomolecular Chemistry in 2019. Application of 10365-98-7 The author mentioned the following in the article:

A fluoroalkenylation of boronic acids with fluoroalkyl alkenes has been developed. The Pd-catalyzed oxidative Heck coupling reaction proceeds under an oxygen atm. at room temperature, in the absence of a base and/or a ligand, showing excellent practicality of the process. This simple transformation is highly stereoselective to provide only E-isomers. In addition to the general approach using alkenes with functionalized fluoroalkyl reagents, this method, by transferring an aromatic system to the electron-deficient fluoroalkyl alkene, provides an efficient alternative method to yield valuable organofluorines. The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7Application of 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Application of 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Expedient synthesis of highly substituted 3,4-dihydro-1,2-oxathiine 2,2-dioxides and 1,2-oxathiine 2,2-dioxides: revisiting sulfene additions to enaminoketones》 were Aiken, Stuart; Anozie, Kelechi; de Azevedo, Orlando D. C. C.; Cowen, Lewis; Edgar, Ross J. L.; Gabbutt, Christopher D.; Heron, B. Mark; Lawrence, Philippa A.; Mills, Abby J.; Rice, Craig R.; Urquhart, Mike W. J.; Zonidis, Dimitrios. And the article was published in Organic & Biomolecular Chemistry in 2019. Name: N,N-Dimethylformamide Dimethyl Acetal The author mentioned the following in the article:

Diversely substituted 1,2-oxathiine 2,2-dioxides, including 3,5,6-triaryl-, 3,6-diaryl-, 3,5-diaryl-, 5,6-diaryl- and selected fused heterocyclic analogs, have been efficiently obtained by the application of a mild Cope elimination of a 4-amino moiety from the requisite 4-amino-3,4-dihydro-1,2-oxathiine 2,2-dioxides, which themselves were readily obtained by the addition of sulfenes to enaminoketones. In addition to this study using N,N-Dimethylformamide Dimethyl Acetal, there are many other studies that have used N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Name: N,N-Dimethylformamide Dimethyl Acetal) was used in this study.

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Name: N,N-Dimethylformamide Dimethyl Acetal

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Palladium-Catalyzed Direct C-H Arylation of Arenes Promoted by Quaternary Ammonium Salt》 was published in Asian Journal of Organic Chemistry in 2020. These research results belong to Yang, Sabyuk; Hong, Soon Hyeok. Computed Properties of C7H7BrO The article mentions the following:

A new Pd-based catalytic system for the direct C-H arylation of arenes was developed. The use of a substoichiometric amount of quaternary ammonium salt as an additive with a Pd source achieved the direct arylation of unactivated arenes under milder reaction conditions in moderate to high yields. The ammonium salt generated the anionic palladium complex, thereby facilitating arylation by a concerted metalation-deprotonation process. In the experiment, the researchers used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Computed Properties of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Computed Properties of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Palladium nanoparticles encapsulated in MIL-101-NH2 catalyzed one-pot reaction of Suzuki-Knoevenagel reaction》 were Li, Jia-Xin; Li, Xin; Tang, Hong; Zhang, Yu-Yang; Han, Zheng-Bo. And the article was published in Inorganic Chemistry Communications in 2019. COA of Formula: C7H9BO3 The author mentioned the following in the article:

Bifunctional Cr-MOF catalysts containing palladium nanoparticles (NPs) have been prepared Combining the high activity of Pd NPs and base sites in MIL-101-NH2, the catalysts (Pd@MIL-101-NH2) exhibited distinct catalytic activity in a one-pot Suzuki-Knoevenagel reaction. Pd@MIL-101-NH2 has been characterized by x-ray diffraction (XRD), transmission electron microscopy (TEM), thermogravimetric anal. (TGA), and fourier transform IR spectroscopy (FT-IR). Various substituted phenylboronic acids were used to research the one-pot reaction. The results were highly satisfactory, not only got high yield, but reduced reaction time. Leakage experiments further demonstrated that there is no leaching of active palladium nanoparticles during the reactions. Catalysts could be reused for at least five cycles and activity is not significantly decreased.3-Methoxyphenylboronic acid(cas: 10365-98-7COA of Formula: C7H9BO3) was used in this study.

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.COA of Formula: C7H9BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Crystal Structures of Spiro Derivatives Including 6,10-Dioxaspiro[4.5]decane-7,9-dione Group and Their Spectral Studies》 were Zeng, Wulan; Wang, Xia. And the article was published in Journal of Chemical Crystallography in 2019. Formula: C5H13NO2 The author mentioned the following in the article:

A new intermediate, I (C22H30N2O8) was attained by reaction of 6,10-dioxaspiro[4.5]decane-7,9-dione with 1,1-dimethoxy-n,n-dimethyl-methanamine in ethanol. The two oxaspirocyclic compounds, 8-[[(2-methylphenyl)amino]methylene]-6,10-dioxaspiro[4.5]decane-7,9-dione (2-C16H17NO4) and 8-[[(2-methylphenyl)amino]methylene]-6,10-dioxaspiro[4.5]decane-7,9-dione (3-C16H17NO4) were prepared by adding 2-methylbenzenamine and 3-methylbenzenamine into to the ethanol solution of I, resp. Two crystals (I and C16H17NO4 ) were determined by single-crystal X-ray diffraction. The compound of I includes one (C5H13N2)+ cation and one (C17H17O8)- anion, which indicates it is a salt. There is no classical hydrogen bonds in I. However, there is one kind of N-H···O intramol. interactions and one kind of C-H···O intermol. interactions in (2-C16H17NO4). In addition, the fluorescence spectra of 2-C16H17NO4 and 3-C16H17NO4 in dilute ethanol were studied, which they exhibit purplish red emission and reddish purple emission, resp. In the experimental materials used by the author, we found N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Formula: C5H13NO2)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Formula: C5H13NO2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Nickel-Catalyzed Construction of 2,4-disubstituted Imidazoles via C-C Coupling and C-N Condensation Cascade Reactions》 were Fang, Shengyang; Yu, Haihua; Yang, Xicheng; Li, Jianqi; Shao, Liming. And the article was published in Advanced Synthesis & Catalysis in 2019. Synthetic Route of C7H9BO3 The author mentioned the following in the article:

A convenient Ni(II)-catalyzed C-C and C-N cascade coupling reaction was developed to directly access various 2,4-disubstituted imidazoles [e.g., N-(cyanomethyl)acetamide + phenylboronic acid → 2-methyl-4-phenyl-1H-imidazole (87%)]. The reaction scope covers a variety of aryl and aliphatic substitutions, which demonstrate moderate-to-excellent yields. The tolerance of halogen and N-containing heterocyclic groups demonstrates the versatility of this method for further synthetic explorations. The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7Synthetic Route of C7H9BO3)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Synthetic Route of C7H9BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《A Convenient Synthetic Route of Diethyl (4-Oxo-chromeno[2,3-d]pyrimidin-2(5)-yl)phosphonates》 were Ali, Tarik E.; Assiri, Mohammed A.; Hassanin, Noha M.; Yahia, I. S.; Hussien, Mai S. A.. And the article was published in Journal of Heterocyclic Chemistry in 2019. Quality Control of N,N-Dimethylformamide Dimethyl Acetal The author mentioned the following in the article:

Novel di-Et (4-oxo-3,4-dihydro-2H-chromeno[2,3-d]pyrimidin-2-yl)phosphonate as two enantiomers and di-Et (4-oxo-1,5-dihydro-4H-chromeno[2,3-d]pyrimidin-5-yl) phosphonate were obtained in easy procedure via reaction of 2-imino-2H-chromene-3-carboxamide, DMF dimethyl-acetal, and di-Et phosphite in a simple one pot. Possible reaction mechanisms are proposed. The structures of the obtained products were confirmed by elemental analyses and spectral tools. The experimental process involved the reaction of N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Quality Control of N,N-Dimethylformamide Dimethyl Acetal)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Quality Control of N,N-Dimethylformamide Dimethyl Acetal

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of Molecular Structure included an article by Davarpanah, Jamal; Ghahremani, Mahboubeh; Najafi, Ozhan. Formula: C8H8O2. The article was titled 《Synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via Hantzsch reaction using nicotinic acid as a green and reusable catalyst》. The information in the text is summarized as follows:

A rapid, efficient and eco-friendly protocol has been developed for the preparation of various 1,4-dihydropyridine and polyhydroquinoline derivatives in the presence of nicotinic acid as a green and dual catalyst under solvent-free conditions. In this reaction, nicotinic acid shows a highly catalytic nature, easy to handle procedure, short reaction time, recycle exploitation and excellent isolated yields. Furthermore, the 1H and 13C chem. shift and X-ray spectra values together with the structural parameters of 1,4-dihydropyridine and polyhydroquinoline have been computed and the scaled values have been compared with the corresponding exptl. NMR and X-ray spectra. As a result, the calculated 1H and 13C chem. shift and X-ray spectra show a good agreement with the exptl. results. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Formula: C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Formula: C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Applied Organometallic Chemistry included an article by Moradi, Parisa; Hajjami, Maryam; Valizadeh-Kakhki, Fatemeh. Name: 1-Bromo-3-methoxybenzene. The article was titled 《Biochar as heterogeneous support for immobilization of Pd as efficient and reusable biocatalyst in C-C coupling reactions》. The information in the text is summarized as follows:

Biochar nanoparticles (BNPs) was modified with 3-choloropropyltrimtoxysilane and further 2-(thiophen-2-yl)-1H-benzo[d]imidazole was anchored on its surface. Then, palladium nanoparticles were fabricated on the surface of the modified BNPs and further the catalytic application was studied as recyclable biocatalyst in carbon-carbon coupling reactions such as Suzuki-Miyaura and Heck-Mizoroki cross-coupling reactions to afford biaryl compounds R-R1 [R = Ph, 3,4-FC6H3; R1 = Ph, 4-BrC6H4, 2-naphthyl, etc.] and phenyl-acrylates R2CH=CHR3 [R2 = CO2Bu, CO2Me, CN; R3 = Ph, 2-MeC6H4, 4-MeOC6H4, etc.] was reported. The structure of the catalyst was characterized using SEM, transmission electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric anal., X-ray diffraction and at. absorption spectroscopy. In the experiment, the researchers used many compounds, for example, 1-Bromo-3-methoxybenzene(cas: 2398-37-0Name: 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Name: 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Ye, Fei; Berger, Florian; Jia, Hao; Ford, Joseph; Wortman, Alan; Boergel, Jonas; Genicot, Christophe; Ritter, Tobias. Recommanded Product: 2-Methoxybenzaldehyde. The article was titled 《Aryl Sulfonium Salts for Site-Selective Late-Stage Trifluoromethylation》. The information in the text is summarized as follows:

Incorporation of the CF3 group into arenes has found increasing importance in drug discovery. Herein, we report the first photoredox-catalyzed cross-coupling of aryl thianthrenium salts with a copper-based trifluoromethyl reagent, which enables a site-selective late-stage trifluoromethylation of arenes. The reaction proceeds with broad functional group tolerance, even for complex small mols. on gram scale. The method was further extended to produce pentafluoroethylated derivatives In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 2-Methoxybenzaldehyde)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Recommanded Product: 2-Methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem