Tag: 100-200

Nitrofullerene as an electrolyte-compatible additive for high-performance sodium metal batteries was written by Li, Pengju;Jiang, Zhipeng;Huang, Xiaobo;Lu, Xing;Xie, Jia;Cheng, Shijie. And the article was included in Nano Energy in 2021.Product Details of 112-49-2 This article mentions the following:

Electrolyte additives have an important impact on the cycling stability of sodium metal batteries, but their applications are severely impeded by the poor compatibility with different electrolytes. Herein, rational incorporation of nitro groups on fullerene (C₆₀) cage yields nitrofullerene (C₆₀(NO₂)₆) as an effective additive, which displays high compatibility with different electrolytes and can enable highly reversible and dendrite-free plating/stripping of sodium metal anodes (SMAs). In-situ optical observation of Na electrodeposition confirms a great improvement in the cycling stability of metallic Na anodes with the C₆₀(NO₂)₆ additive, which not only promotes the formation of stable protective layers on SMAs, but also facilitates the uniform Na deposition and effectively suppresses the Na dendrite growth. As a result, the Na||Na sym. cells with C₆₀(NO₂)₆ show low voltage hysteresis, high rate capability and prolonged cycle life in both carbonate and ether electrolytes. Even at 5 mA cm^-2 and 5 mAh cm^-2, the Na||Cu half cells can stably cycle over 450 h in the ether electrolyte. Furthermore, a significantly improved cycling stability of the high loading Na||Na₃V₂(PO₄)₃@C (8.7 mg cm^-2) full cell is achieved in the carbonate electrolyte. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Product Details of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Product Details of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalyst-Free Photoredox Addition-Cyclisations: Exploitation of Natural Synergy between Aryl Acetic Acids and Maleimide was written by Manley, David W.;Mills, Andrew;O’Rourke, Christopher;Slawin, Alexandra M. Z.;Walton, John C.. And the article was included in Chemistry – A European Journal in 2014.Synthetic Route of C9H10O4 This article mentions the following:

Suitably functionalized carboxylic acids undergo a previously unknown photoredox reaction when irradiated with UVA in the presence of maleimide. Maleimide was found to synergistically act as a radical generating photoxidant and as a radical acceptor, negating the need for an extrinsic photoredox catalyst. Modest to excellent yields of the product chromenopyrroledione, thiochromenopyrroledione and pyrroloquinolinedione derivatives were obtained in thirteen preparative photolyses. In situ NMR spectroscopy was used to study each reaction. Reactant decay and product build-up were monitored, enabling reaction profiles to be plotted. A plausible mechanism, whereby photo-excited maleimide acts as an oxidant to generate a radical ion pair, has been postulated and is supported by UV/Vis. spectroscopy and DFT computations. The radical-cation reactive intermediates were also characterized in solution by EPR spectroscopy. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Synthetic Route of C9H10O4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Synthetic Route of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Enamines. Part III. A new synthesis of substituted 2-arylisatogens and o-nitrophenyl benzyl ketones was written by Bhamare, N. K.;Kamath, H. V.;Kulkarni, Sheshgiri N.. And the article was included in Indian Journal of Chemistry in 1986.Recommanded Product: 5367-32-8 This article mentions the following:

The (nitrobenzoyl)morpholinostyrenes I [R, R₁, R² = 4-NO₂, H, H; 4-NO₂, H, 5-MeO; 2-NO₂, 5-MeO, H; 4-NO₂, H, 4,5-(MeO)₂], prepared from the corresponding morpholinostyrene and o-nitrobenzoyl chloride, were hydrolyzed to give the o-nitrophenyl benzyl ketones II. I and II underwent cyclodehydration with AcONa/EtOH to give the isatogens III. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Recommanded Product: 5367-32-8).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Recommanded Product: 5367-32-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A novel cyanoacrylate-based matrix excipient in HPMCP capsules forms a sustained intestinal delivery system for orally administered drugs with enhanced absorption efficiency was written by Song, Liya;Chen, Pengfei;Yu, Jin;Han, Xiaolu;Hua, Yabing;Liu, Shan;Pang, Bo;Gao, Jing;Ma, Jiahua;Xu, Liang. And the article was included in Journal of Materials Chemistry B: Materials for Biology and Medicine in 2021.Quality Control of 2-(2-Methoxyethoxy)ethanol This article mentions the following:

Patients prefer oral drug delivery due to its convenience and noninvasiveness. Nevertheless, a multitude of potentially clin. important drugs will not reach the market or achieve their full potential, due to their low bioavailability and instability in gastric acid. In this study, a novel oral drug delivery system based on poly-cyanoacrylate [a polymer of 2-(2-methoxyethoxy)ethyl-2-cyanoacrylate (MECA)] and hydroxypropyl methylcellulose phthalate (HPMCP) was developed and shown to permit intestinal targeting and sustained drug release. Aspirin [acetylsalicylic acid (ASA)] was selected as a model drug for atherosclerosis treatment. It was phys. dissolved in liquid MECA, and the ASA-MECA matrix was then polymerized into a solid drug-loading depot in an HPMCP shell. The delivery of the drug depot in the intestine was achieved with the HPMCP shell; then the polymerized MECA (polyMECA) provided sustained drug release. The polyMECA excipient was not absorbed by the intestine due to its high mol. weight; a fluorescein-labeled assay indicated that it was excreted completely in feces after drug release. The formulation, ASA-polyMECA-HPMCP, showed good intestinal targeting and sustained drug release in vitro and in vivo. Pharmacokinetic studies indicated that this formulation improved the bioavailability of ASA relative to com. available controls. ASA-polyMECA-HPMCP showed desirable anti-atherosclerosis efficacy in a rabbit model, with significant enhancement of atheromatous lesion stability. Biosafety tests proved the low toxicity of ASA-polyMECA-HPMCP and the polyMECA matrix. We believe that this work has provided a practical and biocompatible system for sustained intestinal drug delivery that can be applied broadly with various drugs for specific therapeutic aims. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Quality Control of 2-(2-Methoxyethoxy)ethanol).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Quality Control of 2-(2-Methoxyethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chemical Defense in Millipedes (Myriapoda, Diplopoda): Do Representatives of the Family Blaniulidae Belong to the ‘Quinone’ Clade? was written by Vujisic, Ljubodrag V.;Antic, Dragan Z.;Vuckovic, Ivan M.;Sekulic, Tatjana Lj.;Tomic, Vladimir T.;Mandic, Boris M.;Tesevic, Vele V.;Curcic, Bozidar P. M.;Vajs, Vlatka E.;Makarov, Slobodan E.. And the article was included in Chemistry & Biodiversity in 2014.Name: 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione This article mentions the following:

The defensive secretions of 2 blaniulid millipedes, Nopoiulus kochii and Cibiniulus phlepsii, were characterized by GC-FID and GC/MS analyses, which showed the presence of a complex mixture of benzoquinones, hydroquinones, and oleates. Altogether, 13 compounds were identified. The major compound in the secretions of both analyzed species was 2-methyl-1,4-benzoquinone (toluquinone). The 2nd major constituent in the N. kochii secretion was 2-methyl-3,4-(methylenedioxy)phenol, while in that of C. phlepsii, it was 2-methoxy-3-methyl-1,4-benzoquinone. The defensive secretion of N. kochii also showed a high content of hydroquinones (13.5%) in comparison to that of C. phlepsii (0.8%). Hexyl oleate and octyl oleate were detected for the 1st time in defensive millipede fluids. The chem. composition of the defensive secretions supports the chemotaxonomic position of the family Blaniulidae in the quinone millipede clade. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Name: 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Name: 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Correlation of the empirical polarity parameters of solvate ionic liquids (SILs) with molecular structure was written by Potangale, Mangesh;Tiwari, Shraeddha. And the article was included in Journal of Molecular Liquids in 2020.Application of 112-49-2 This article mentions the following:

Empirical polarity parameters for 10 solvate ionic liquids (SILs) have been determined using Catalans probes. The solvation environment surrounding the probe mols. in the SILs is dependent on the mutual interactions between the cation, anion and chelating ligand, leading to characteristic values of the polarity parameters. The acidity of the SILs is comparable to the acidity of polar protic solvents, which is attributed to the ability of the Li cation to interact with the probe in a manner similar to H-bond donor. The choice of anion influenced the measured acidity of SILs by determining the extent of cation-probe interactions possible. The basicity showed a strong correlation with the nature of the anion but was also influenced by the extent of cation-anion interaction and choice of ligand. Temperature dependence of polarity parameters in SILs is relatively small, but shows some interesting trends. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Application of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Application of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Utilization of wood industrial wastes for production of chemicals and pharmaceuticals was written by Shams, Alaa E.;Soliman, Amal F.;Ashour, Ahmed;Marzouk, Amani M.;Elsharkawy, Saleh H.. And the article was included in Indian Journal of Science and Technology in 2020.Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde This article mentions the following:

Objectives: This study aims to isolate and identify valuable chems. and pharmaceuticals from the waste of wood (Pinus sylvestris L.) industry and to determine their biol. value. Methods: Chromatog. technique was used to isolate compounds from the waste. The chem. identity of the isolated compounds were evidenced by different spectroscopic analyses as well as comparative studies of reported data. The microbial transformed product of pinosylvin mono Me ether was quant. determined using fluorimetric method. All the isolated compounds were tested for their antitoxoplasmosis activity (in vitro) against Toxoplasma gondii. Findings/ Novelty: Nine compounds were isolated and identified including three diterpenes : (1β-hydroxy dehydroabietic acid, 15-hydroxy dehydroabietic acid and Methyl-15-hydroxy dehydroabiet-18-ate) ; two aromatic aldehydes (coniferaldhyde and 3-hydroxy, 5-methoxy benzaldhyde) ; two stilbene derivatives; (Pinosylvin and Pinosylvin mono Me ether) ; a flavan: (Pinocembrin) and a phytosterol (β-sitosterol). For the first time, the fluorimetric method was used for quant. determination of the novel metabolite produced, E-Pinosylvin mono Me ether 5-O-β-D-glucopyranoside, from the microbial biotransformation technique. All isolated compounds showed variable antitoxopasmosis activity, carried out for the first time, against T. gondii according to their % mortality and recorded EC50. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde).

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Catalyst-Free α-Alkylation-α-Hydroxylation of Oxindole with Alcohols was written by Wu, Siwei;Song, Wei;Zhu, Runyu;Hu, Jingwen;Zhao, Lin;Li, Zheyao;Yu, Xinhong;Xia, Chengcai;Zhao, Jianhong. And the article was included in Journal of Organic Chemistry in 2022.Name: (4-Methoxyphenyl)methanol This article mentions the following:

A green and economical protocol for the synthesis of 3-alkyl-3-hydroxyoxindoles I [R¹ = H, 6-Cl, 6-Br, etc.; R² = Ph, 2-ClC₆H₄, 2-pyridyl, etc.] was developed for the first time via α-alkylation-α-hydroxylation of oxindole with aryl alcs. without using any transition-metal catalysts in yields of 29-93%. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Name: (4-Methoxyphenyl)methanol).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Name: (4-Methoxyphenyl)methanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of aryloxyacetic acids using tributylethylammonium ethylsulfate as phase transfer catalyst was written by Li, Yiqun. And the article was included in Huaxue Shiji in 2000.SDS of cas: 1877-75-4 This article mentions the following:

Title compounds ArOCH₂CO₂H (Ar = 4-CH₃OC₆H₄, 4-CH₃C₆H₄, 2-CH₃C₆H₄, 3-CH₃C₆H₄, C₆H₅, 1-naphthyl, 2-naphthyl, 2-ClC₆H₄, 2,4-Cl₂C₆H₃) were prepared in CH₃CN in the presence of phase transfer catalyst (Bu₃(Et)NSO₄Et) by reflux. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4SDS of cas: 1877-75-4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.SDS of cas: 1877-75-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

N-Hydroxyphthalimide-catalyzed chemoselective intermolecular benzylic C-H amination of unprotected arylalkanols was written by Shibuya, Masatoshi;Orihashi, Takayuki;Li, Yamei;Yamamoto, Yoshihiko. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2021.Application In Synthesis of 3-(3,4-Dimethoxyphenyl)propan-1-ol This article mentions the following:

N-Hydroxyphthalimide-catalyzed chemoselective benzylic C(sp³)-H amination of unprotected arylalkanols using bis(2,2,2-trichloroethyl)azodicarboxylate were developed. The use of 1,1,1,3,3,3-hexafluoropropan-2-ol as a solvent played a critical role in chemoselectivity. The conversion of an aminated product to the corresponding free amino alc. was also demonstrated. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Application In Synthesis of 3-(3,4-Dimethoxyphenyl)propan-1-ol).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Application In Synthesis of 3-(3,4-Dimethoxyphenyl)propan-1-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem