Tag: 100-200

Structural effects on the OH^–-promoted fragmentation of methoxy-substituted 1-arylalkanol radical cations in aqueous solution: the role of oxygen acidity was written by Baciocchi, Enrico;Bietti, Massimo;Gerini, Maria Francesca;Manduchi, Laura;Salamone, Michela;Steenken, Steen. And the article was included in Chemistry – A European Journal in 2001.Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol This article mentions the following:

A kinetic and product study of the OH^–-induced decay in H₂O of the radical cations generated from some di- and tri-methoxy-substituted 1-arylalkanols [ArCH(OH)R^·+] and 2- and 3-(3,4-dimethoxyphenyl)alkanols has been carried out by using pulse- and γ-radiolysis techniques. In the 1-arylalkanol system, the radical cation 3,4-(MeO)₂C₆H₃CH₂-OH^·+ decay at a rate more than two orders of magnitude higher than that of its Me ether; this indicates the key role of the side-chain OH group in the decay process (oxygen acidity). However, quite a large deuterium kinetic isotope effect (3.7) is present for this radical cation compared with its α-dideuterated counterpart. A mechanism is suggested in which a fast OH deprotonation leads to a radical zwitterion which then undergoes a rate-determining 1,2-H shift, coupled to a side-chain-to-ring intramol. electron transfer (ET) step. This concept also attributes an important role to the energy barrier for this ET, which should depend on the stability of the pos. charge in the ring and, hence, on the number and position of methoxy groups. On a similar exptl. basis, the same mechanism is suggested for 2,5-(MeO)₂C₆H₃CH₂OH^·+ as for 3,4-(MeO)₂C₆H₃CH₂OH^·+, in which some contribution from direct C-H deprotonation (carbon acidity) is possible. In fact, the latter process dominates the decay of the trimethoxylated system 2,4,5-(MeO)₃C₆H₂CH₂-OH^·+, which, accordingly, reacts with OH^– at the same rate as that of its Me ether. Thus, a shift from oxygen to carbon acidity is observed as the pos. charge is increasingly stabilized in the ring; this is attributed to a corresponding increase in the energy barrier for the intramol. ET. When R = tBu, the OH^–-promoted decay of the radical cation ArCH(OH)R^·+ leads to products of C-C bond cleavage. With both Ar = 3,4- and 2,5-dimethoxyphenyl the reactivity is three orders of magnitude higher than that of the corresponding cumyl alc. radical cations; this suggests a mechanism in which a key role is played by the oxygen acidity as well as by the strength of the scissile C-C bond: a radical zwitterion is formed which undergoes a rate-determining C-C bond cleavage, coupled with the intramol. ET. Finally, oxygen acidity also determines the reactivity of the radical cations of 2-(3,4-dimethoxyphenyl)ethanol and 3-(3,4-dimethoxyphenyl)propanol. In the former the decay involves C-C bond cleavage, in the latter it leads to 3-(3,4-dimethoxyphenyl)propanal. In both cases no products of C-H deprotonation were observed Possible mechanisms, again involving the initial formation of a radical zwitterion, are discussed. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Recommanded Product: 3-(3,4-Dimethoxyphenyl)propan-1-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hydrogen-bond super-amphiphile based drug delivery system: design, synthesis, and biological evaluation was written by Chen, Jiali;Huang, Haolong;Lu, Ruilin;Wan, Xiaohui;Yao, Yongchao;Yang, Tian;Li, Pengfei;Ning, Ning;Zhang, Shiyong. And the article was included in RSC Advances in 2022.Recommanded Product: 111-77-3 This article mentions the following:

Drug delivery systems (DDSs) show great application prospects in tumor therapy. So far, phys. encapsulation and covalent grafting were the two most common strategies for the construction of DDSs. However, phys. encapsulation-based DDSs usually suffered from low drug loading capacity and poor stability, and covalent grafting-based DDSs might reduce the activity of original drug, which greatly limited their clin. application. Therefore, it is of great research value to design a new DDS with high drug loading capacity, robust stability, and original drug activity. Herein, we report a super-amphiphile based drug delivery system (HBS-DDS) through self-assembly induced by hydrogen bonds between amino-substituted N-heterocycles of the 1,3,5-triazines and hydrophilic carmofur (HCFU). The resulting HBS-DDS had a high drug loading capacity (38.1%) and robust stability. In addition, the drug delivery system exhibited pH-triggered size change and release of drugs because of the pH responsiveness of hydrogen bonds. In particular, the anticancer ability test showed that the HBS-DDS could be efficiently ingested by tumor cells, and its half-maximal inhibitory concentration (IC50 = 3.53μg mL-1) for HeLa cells was close to that of free HCFU (IC50 = 5.54μg mL-1). The hydrogen bond-based DDS represents a potential drug delivery system in tumor therapy. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Recommanded Product: 111-77-3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Recommanded Product: 111-77-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Antitumor properties of Coenzyme Q₀ against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy was written by Hseu, You-Cheng;Tsai, Tai-Jung;Korivi, Mallikarjuna;Liu, Jer-Yuh;Chen, Hui-Jye;Lin, Chung-Ming;Shen, Yi-Chun;Yang, Hsin-Ling. And the article was included in Scientific Reports in 2017.Computed Properties of C9H10O4 This article mentions the following:

Coenzyme Q₀ (CoQ₀, 2,3-dimethoxy-5-methyl-1,4-benzoquinone) has been reported to exert anticancer properties against human breast/lung cancer cells. This study investigated the in vitro and in vivo anticancer properties of CoQ₀ on human ovarian carcinoma (SKOV-3) cells and xenografted nude mice, and revealed the underlying mol. mechanism. CoQ₀ induced G₂/M arrest through downregulation of cyclin B1/A and CDK1/K2 expressions. CoQ₀-induced autophagy as a survival mechanism was evidenced by increased accumulation of LC3-II, GFP-LC3 puncta, AVOs formation and Beclin-1/Bcl-2 dysregulation. Increased TUNEL-pos. cells and Annexin-V/PI stained cells indicated CoQ₀-induced late apoptosis. Both mitochondrial (caspase-3, PARP and Bax/Bcl-2 dysregulation) and ER stress (caspase-12 and Hsp70) signals are involved in execution of apoptosis. Interestingly, CoQ₀-induced apoptosis/autophagy is associated with suppression of HER-2/neu and PI₃K/AKT signalling cascades. CoQ₀ triggered intracellular ROS production, whereas antioxidant N-acetylcysteine prevented CoQ₀-induced apoptosis, but not autophagy. Inhibition of apoptosis by Z-VAD-FMK suppressed CoQ₀-induced autophagy (diminished LC3-II/AVOs), indicates CoQ₀-induced apoptosis led to evoke autophagy. Contrary, inhibition of autophagy by 3-MA/CQ potentiated CoQ₀-induced apoptosis (increased DNA fragmentation/PARP cleavage). Furthermore, CoQ₀ treatment to SKOV-3 xenografted nude mice reduced tumor incidence and burden. Histopathol. analyses confirmed that CoQ₀ modulated xenografted tumor progression by apoptosis induction. Our findings emphasize that CoQ₀ triggered ROS-mediated apoptosis and cytoprotective autophagy. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Computed Properties of C9H10O4).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Computed Properties of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Aza steroids. II. Approaches to the 13-azaequilenin system was written by Schleigh, William R.;Catala, Adria;Popp, Frank D.. And the article was included in Journal of Heterocyclic Chemistry in 1965.HPLC of Formula: 3929-47-3 This article mentions the following:

The synthesis of N-[2-(1-naphthyl)ethyl] succinimide, N-[2-(1-naphthyl)ethyl]pyrrolidone, and the corresponding 3,4-dihydro compounds is described. The pyrrolidones have been converted into 11,12,16,17-tetrahydro-13-azacyclopenta[a]phenanthrene and 6,7,11,12,16,17 – hexahydro – 13 – azacyclopenta[a]phenanthrene. These 2 compounds were then converted to I and II. The former compound is a salt of (+)-3-deoxy-17-deoxo-13-azaequilenin. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3HPLC of Formula: 3929-47-3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.HPLC of Formula: 3929-47-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Properties of magnesium electrode covered with magnesium chloride-modified graphene oxide was written by Egashira, Minato;Hiratsuka, Kaori. And the article was included in Electrochemistry (Tokyo, Japan) in 2021.HPLC of Formula: 112-49-2 This article mentions the following:

For the modification of reversibility of magnesium deposition-dissolution in non-aqueous glyme-based electrolytes, the surface of a magnesium metal or magnesium alloy AZ31 was covered by graphene oxide modified using Grignard reagent. After modification, the magnesium chloride moieties appeared to connect with oxygen-containing functional groups of graphene oxide. The magnesium electrode covered with MgCl-modified graphene oxide exhibited a reversible redox reaction assigned to the deposition-dissolution of magnesium from the substance without overpotential in a conventional magnesium salt – glyme solution The MgCl-modified graphene oxide-covered magnesium alloy electrode was compatible with two-electrode test cells with Mo6S8 pos. electrode. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2HPLC of Formula: 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.HPLC of Formula: 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-β-D-glucan derived from the fruiting body of Antrodia camphorata was written by Lee, Chu-I.;Wu, Chih-Chung;Hsieh, Shu-Ling;Lee, Chun-Lin;Chang, Yueh-Ping;Chang, Chih-Chuan;Wang, Yi-Zhen;Wang, Jyh-Jye. And the article was included in Food & Function in 2014.Synthetic Route of C9H10O4 This article mentions the following:

Antrodia camphorata is a fungus native to Taiwan, and it is considered a precious medicinal agent. We analyzed triterpenoids, polysaccharides and 1,3-β-D-glucan, three major effective components in A. camphorata extracts (ACE). ACE exhibited a selective cytotoxic effect on BxPC-3 human pancreatic cancer cells. ACE markedly inhibited the migration ability of BxPC-3 cells. Treatment of BxPC-3 cells with ACE resulted in the increase of cells in the sub-G1 phase and G2/M phase arrest. Apoptosis was confirmed by validating phosphatidylserine externalization, the observation of characteristic chromatin condensation, and nuclear DNA fragmentation. ACE induced apoptosis in BxPC-3 cells through a mitochondria-dependent pathway by triggering an appropriate balance of bax/bcl-2, cytochrome c release, activation of caspase-9 and -3, and poly(ADP-ribose) polymerase cleavage. ACE shows great therapeutic potential due to its cytotoxic effects against BxPC-3 cells which include inhibiting cell migration and inducing mitochondria-mediated apoptosis. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Synthetic Route of C9H10O4).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Synthetic Route of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of Dihydropyrazoles via Pd-Catalyzed Heterocyclization/Carbonylation Reaction: Development and Parameterization Studies was written by Barboza, Amanda A.;Dantas, Juliana A.;Jardim, Guilherme A. M.;Neto, Attilio C.;Oliveira, Willian X. C.;Gensch, Tobias;Ferreira, Marco A. B.. And the article was included in ChemCatChem in 2022.Recommanded Product: (4-Methoxyphenyl)methanol This article mentions the following:

A Pd-catalyzed heterocyclization/carbonylation cascade reaction of benzenesulfonyl hydrazones and alcs. encompassing the formation of 3 new bonds, affording alkyl 2-(3-aryl-1-tosyl-4,5-dihydro-1H-pyrazol-5-yl)acetates I [R = Me, Et, Bn, etc.; R¹ = i-Pr, Ph, Cy, etc.; R² = Ph, 4-MeC₆H₄, 4-BrC₆H₄, etc.] in moderate to excellent yields and good functional group tolerance was described, comprising a new methodol. for direct access to esterified heterocycles using alcs. as readily available feedstock. Optimization was carried out along with a phosphine/base parameterization study, providing important structure-reactivity insights for pyridine-bases, mono- and bisphosphines. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Recommanded Product: (4-Methoxyphenyl)methanol).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Recommanded Product: (4-Methoxyphenyl)methanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Novel ester derivative of cinnamates with different long alkoxy chain: synthesis, mesomorphic properties, biological evaluation was written by Bhalodiya, Pradip C.;Patel, Hemant N.;Parmar, Tejasvi H.;Sangani, Chetan B.;Rajani, Dhanji P.. And the article was included in Molecular Crystals and Liquid Crystals in 2021.Application In Synthesis of 2-(2-Methoxyethoxy)ethanol This article mentions the following:

A novel series of liquid crystals involving cinnamate-based mesogenic units interlinked between aromatic ester and alkyl bromide were designed and synthesized. The mesomorphic behavior of novel synthesized materials was investigated through a polarizing optical microscope, differential scanning calorimetry, and thermogravimetric anal. (TGA) anal. The lower carbon chain substituted member showed nematic phase while compound possess higher carbon chain exhibited only SmC phase. Thermal stability is determined by TGA anal. All the cinnamate derivatives were screened for their anti-microbial, anti-malarial, and anti-tuberculosis potency. Among them, most of the derivatives exhibited outstanding anti-bacterial and anti-tuberculosis activity. Some derivatives also exhibited potent anti-fungal activity. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Application In Synthesis of 2-(2-Methoxyethoxy)ethanol).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Application In Synthesis of 2-(2-Methoxyethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and Aerobic Oxidation Catalysis of Mesoporous Todorokite-Type Manganese Oxide Nanoparticles by Crystallization of Precursors was written by Koutani, Maki;Hayashi, Eri;Kamata, Keigo;Hara, Michikazu. And the article was included in Journal of the American Chemical Society in 2022.Safety of (4-Methoxyphenyl)methanol This article mentions the following:

The pursuit of a high surface area while maintaining high catalytic performance remains a challenge due to a trade-off relationship between these two features in some cases. In this study, mesoporous todorokite-type manganese oxide (OMS-1) nanoparticles with high sp. surface areas were synthesized in one step by a new synthesis approach involving crystallization (i.e., solid-state transformation) of a precursor produced by a redox reaction between MnO₄^– and Mn²⁺ reagents. The use of a low-crystallinity precursor with small particles is essential to achieve this solid-state transformation into OMS-1 nanoparticles. The sp. surface area reached up to ca. 250 m² g^-1, which is much larger than those (13-185 m² g^-1) for Mg-OMS-1 synthesized by previously reported methods including multistep synthesis or dissolution/precipitation processes. Despite ultrasmall nanoparticles, a linear correlation between the catalytic reaction rates of OMS-1 and the surface areas was observed without a trade-off relationship between particle size and catalytic performance. These OMS-1 nanoparticles exhibited the highest catalytic activity among the Mn-based catalysts tested for the oxidation of benzyl alc. and thioanisole with mol. oxygen (O₂) as the sole oxidant, including highly active β-MnO₂ nanoparticles. The present OMS-1 nanomaterial could also act as a recyclable heterogeneous catalyst for the aerobic oxidation of various aromatic alcs. and sulfides under mild reaction conditions. The mechanistic studies showed that alc. oxidation proceeds with oxygen species caused by the solid, and the high surface area of OMS-1 significantly contributes to an enhancement of the catalytic activity for aerobic oxidation In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Safety of (4-Methoxyphenyl)methanol).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Safety of (4-Methoxyphenyl)methanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

High nitrogen content carbons: Morphological and chemical changes with synthesis temperature and application in lithium-sulfur batteries was written by Arias, Analia Natali;Villarroel-Rocha, Jhonny;Sapag, Karim;Mori, Maria Fernanda;Planes, Gabriel Angel;Tesio, Alvaro Yamil;Flexer, Victoria. And the article was included in Electrochimica Acta in 2020.Application In Synthesis of 2,5,8,11-Tetraoxadodecane This article mentions the following:

The authors present a new two-step synthesis method to prepare N-doped carbons with micro, meso and macroporosity. The authors modified the classical polycondensation of resorcinol-formaldehyde, by adding a large excess of melamine in basic medium. Materials were prepared by varying the maximum carbonization temperature in the range 600-900°, and are denoted NCC-X, where X denotes that maximum temperature NCC-X showed a high N content, ranging from 32.9% to 10.3%. SEM showed macropores in the order of 100-600 nm, with sizes decreasing with temperature, reaching a min. for NCC-800, and then increasing again. N₂ adsorption-desorption isotherms showed micro and mesopores for all samples, with a maximum surface area of 505 m² g^-1 for NCC-800. CO₂ adsorption isotherms showed that all NCC-X materials present ultramicropores. NCC-X were incorporated as host materials for elemental S in Li-S batteries. The increased narrow micropore volume of materials pyrolyzed at higher temperature seems to promote an initial higher cell capacity. Conversely, the much higher N content and the higher amount of N in pyridinic environments were identified as the reasons for the higher cycling stability of the cells prepared with NCC-600-7h and NCC-750. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Application In Synthesis of 2,5,8,11-Tetraoxadodecane).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Application In Synthesis of 2,5,8,11-Tetraoxadodecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem