Tag: M.W=100-150

Lv, Wei published the artcileMolybdenum oxide decorated Ru catalyst for enhancement of lignin oil hydrodeoxygenation to hydrocarbons, Name: 1,2-Dimethoxybenzene, the publication is Renewable Energy (2022), 195-210, database is CAplus.

Herein, the catalysts of ruthenium and molybdenum oxide nanoparticles supported on activated carbon (AC) were synthesized by precursor stepwise impregnation and employed for the hydrodeoxygenation (HDO) of lignin oil. The XRD, TEM, XPS and NH₃-TPD-MS result of RuMoO_x/AC catalysts confirm that the method of loading molybdenum precursor before ruthenium precursor is advantageous for the MoO_x and Ru nanoparticles high dispersion and the reduction of MoO_x species enhance the amount of acidity of catalyst. Meanwhile, the reduction temperature of RuMoO_x/AC-1-T catalysts could effectively regulate the MoO_x species that determine the activity and product distribution of HDO. The conversion of aromatic monomers/dimers were up to 96% with high selectivity of hydrocarbon over RuMoO_x/AC-1-350 catalyst at 160 °C and 30 bar H₂. Which is attributed to the MoO₃ and Ru species possess the excellent activity of benzene ring deep hydrogenation, ether bond breaking and acid dehydration. The RuMoO_x/AC-1-350 catalyst effectively converted lignin oil (from the depolymerization of cornstalk hydrolysis residue) into hydrocarbons (56.9 wt%) and cyclohexanol/ethers (18.7 wt%) under 280 °C and 3 bar H₂. The durability of the RuMoO_x/AC-1-350 catalyst for HDO of lignin oil was also investigated and showed that the RuMoO_x/AC-1-350 catalyst had good stability, regenerability and repeatability.

Renewable Energy published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bai, Xueying published the artcileCatalyst-Free Hydrogen Proton Transfer Reduction of Nitrobenzamides to Aminobenzamides with i-PrOH/KOH System, Formula: C8H11NO, the publication is Asian Journal of Organic Chemistry (2021), 10(11), 2892-2894, database is CAplus.

A reduction of nitrobenzenes via the combination of KOH and isopropanol was established for the general synthesis of aniline derivatives A metal catalyst isn’t required in this alternative reduction reaction, and a series of nitrobenzamide compounds RC₆H₄C(O)NHR¹ (R = 2-NO₂, 3-NO₂, 4-NO₂; R¹ = 4-bromobenzyl, 2,6-diisopropylphenyl, 3-methoxybenzyl, etc.) were chemoselectively reduced into the corresponding aminobenzamides RC₆H₄C(O)NHR¹ (R = 2-NH₂, 3-NH₂, 4-NH₂) in good to excellent yields. This reaction is operationally simple, and proceeds under mild conditions.

Asian Journal of Organic Chemistry published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Formula: C8H11NO.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Percec, Virgil published the artcileSelf-organization of rectangular bipyramidal helical columns by supramolecular orientational memory epitaxially nucleated from a Frank-Kasper σ phase, Product Details of C8H10O2, the publication is Giant (2022), 100084, database is CAplus.

Programming living and soft complex matter via primary structure and self-organization represents the key methodol. employed to design functions in biol. and synthetic nanoscience. Memory effects have been used to create com. technologies including liquid crystal displays and biomedical applications based on shape memory polymers. Supramol. orientational memory (SOM), induced by an epitaxial nucleation mediated by the close contact spheres of cubic phases, emerged as a pathway to engineer complex nanoscale soft matter of helical columnar hexagonal arrays. SOM preserves the crystallog. directions of close contact supramol. spheres from the 3D phase upon cooling to the columnar hexagonal periodic array. Despite the diversity of 3D periodic and quasiperiodic nanoarrays of supramol. dendrimers, including Frank-Kasper and quasicrystal, all examples of SOM to date were mediated by Im3m (body-centered cubic, BCC) and Pm3n (Frank-Kasper A15) cubic phases. Expanding the scope of SOM to non-cubic arrays is expected to generate addnl. morphologies that were not yet available by any other methods. Here we demonstrate the SOM of a dendronized triphenylene that self-organizes into helical columnar hexagonal and tetragonal P4₂/mnm (Frank-Kasper σ) phases. Structural anal. of oriented fibers by X-ray diffraction reveals that helical columnar hexagonal domains self-organize an unusual rectangular bipyramidal morphol. upon cooling from the σ phase. The discovery of SOM in a non-cubic Frank-Kasper phase indicates that this methodol. may be expanded to other periodic and quasiperiodic nanoarrays organized from self-assembling dendrimers and, most probably, to other soft and living complex matter.

Giant published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wu, Zhenyu published the artcileCovalent-organic frameworks with keto-enol tautomerism for efficient photocatalytic oxidative coupling of amines to imines under visible light, HPLC of Formula: 6850-57-3, the publication is Science China: Chemistry (2021), 64(12), 2169-2179, database is CAplus.

Photocatalytic oxidation of organic mols. into highly value-added products is an innovative and challenging research which has gradually attracted remarkable attention of scientists. In this work, it is demonstrated that the COF-TpPa with keto-enol tautomerism equilibrium structure shows excellent performance (yield>99% after 8 h) in the selective photocatalytic oxidative coupling of amines to imines under visible light irradiation It is revealed that three kinds of reactive oxygen species (superoxide radical, hydroxyl radical and singlet oxygen) participate in this photocatalytic oxidation reaction. In addition, hydrogen protons cleaved from the benzyl are proven to be reduced to hydrogen in the conduction band of COF-TpPa in anaerobic atm., accompanied with the formation of imines. The direct hydrogen evolution from amine provides an effective way to extract clean energy from organic mol. as well as the production of value-added chems. As a contrast, COF-LZU1 with similar structure and chem. composition to COF-TpPa but without keto-enol tautomerism exhibits worse optical properties and photocatalytic performance. It is also demonstrated that keto-enol tautomerism favors the adsorption of benzylamine based on the characterization results and theor. calculations

Science China: Chemistry published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C7H7ClN2S, HPLC of Formula: 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chen, Yujie published the artcilePalladium-Catalyzed Isoquinoline Synthesis by Tandem C-H Allylation and Oxidative Cyclization of Benzylamines with Allyl Acetate, Application In Synthesis of 6850-57-3, the publication is Organic Letters (2021), 23(11), 4209-4213, database is CAplus and MEDLINE.

A novel approach to synthesize 3-methylisoquinolines via a one-pot, two-step, palladium(II)-catalyzed tandem C-H allylation/intermol. amination and aromatization is reported. A wide series of 3-methylisoquinoline derivatives were obtained directly using this method in moderate to good yields, and authors highlight the synthetic importance of this new transformation.

Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Application In Synthesis of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Akherati, Ali published the artcileDilution and photooxidation driven processes explain the evolution of organic aerosol in wildfire plumes, Formula: C8H10O2, the publication is Environmental Science: Atmospheres, database is CAplus.

Wildfires are an important atm. source of primary organic aerosol (POA) and precursors for secondary organic aerosol (SOA) at regional and global scales. However, there are large uncertainties surrounding the emissions and physicochem. processes that control the transformation, evolution, and properties of POA and SOA in large wildfire plumes. We develop a plume version of a kinetic model to simulate the dilution, oxidation chem., thermodn. properties, and microphysics of organic aerosol (OA) in wildfire smoke. The model is applied to study the in-plume OA in four large wildfire smoke plumes intercepted during an aircraft-based field campaign in summer 2018 in the western United States. Based on estimates of dilution and oxidant concentrations before the aircraft first intercepted the plumes, we simulate the OA evolution from very close to the fire to several hours downwind. Our model results and sensitivity simulations suggest that dilution-driven evaporation of POA and simultaneous photochem. production of SOA are likely to explain the observed evolution in OA mass with phys. age. The model, however, substantially underestimates the change in the oxygen-to-carbon ratio of the OA compared to measurements. In addition, we show that the rapid chem. transformation within the first hour after emission is driven by higher-than-ambient OH concentrations (3 x 10⁶-10⁷ mols. per cm³) and the slower evolution over the next several hours is a result of lower-than-ambient OH concentrations (<10⁶ mols. per cm³) and depleted SOA precursors. Model predictions indicate that the OA measured several hours downwind of the fire is still dominated by POA but with an SOA fraction that varies between 30% and 56% of the total OA. Semivolatile, heterocyclic, and oxygenated aromatic compounds, in that order, were found to contribute substantially (>90%) to SOA formation. Future work needs to focus on better understanding the dynamic evolution closer to the fire and resolving the rapid change in the oxidation state of OA with phys. age.

Environmental Science: Atmospheres published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Peng, Ting published the artcileDiscovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis, Recommanded Product: (2-Methoxyphenyl)methanamine, the publication is Journal of Medicinal Chemistry (2022), 65(16), 11010-11033, database is CAplus and MEDLINE.

MicroRNAs (miRNAs) are key players in human hepatocellular carcinoma (HCC) tumorigenesis. Therefore, small mols. targeting components of miRNA biogenesis may provide new therapeutic means for HCC treatment. By a high-throughput screening and structural simplification, we identified a small mol., CIB-3b (I), which suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. Mechanistically, CIB-3b phys. binds to transactivation response (TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction, thereby altering the activity of Dicer and mature miRNA production Structure-activity relationship study via the synthesis of 45 CIB-3b derivatives showed that some compounds exhibited a similar inhibitory effect on miRNA biogenesis to CIB-3b. These results support TRBP as a potential therapeutic target in HCC and warrant further development of CIB-3b along with its analogs as a novel therapeutic strategy for the treatment of HCC.

Journal of Medicinal Chemistry published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Recommanded Product: (2-Methoxyphenyl)methanamine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bezencon, Olivier published the artcileDiscovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies, SDS of cas: 2358-54-5, the publication is Journal of Medicinal Chemistry (2017), 60(23), 9769-9789, database is CAplus and MEDLINE.

The authors report the discovery and pharmacol. characterization of N-(1-benzyl-1H-pyrazol-3-yl)-2-phenylacetamide derivatives as potent, selective, brain-penetrating T-type calcium channel blockers. Optimization focused mainly on solubility, brain penetration, and the search for an aminopyrazole metabolite that would be neg. in an Ames test. This resulted in the preparation and complete characterization of compound 66b (ACT-709478 (N-(1-((5-cyanopyridin-2-yl)methyl)-1H-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)acetamide)), which has been selected as a clin. candidate.

Journal of Medicinal Chemistry published new progress about 2358-54-5. 2358-54-5 belongs to ethers-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-(2,2,2-Trifluoroethoxy)ethanol, and the molecular formula is C4H7F3O2, SDS of cas: 2358-54-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Dong, Xiaoyun published the artcileCadmium sulfide/titanate hybrid green light photocatalysis for selective aerobic oxidative homocoupling of amines, Related Products of ethers-buliding-blocks, the publication is Journal of Colloid and Interface Science (2021), 387-395, database is CAplus and MEDLINE.

Semiconductor photocatalysis can carry out selective chem. transformations under ambient conditions, mitigating the associated environmental consequences. However, a single semiconductor photocatalyst usually cannot perform the transformations satisfactorily from the aspects of light-absorption, efficiency, and selectivity, etc. To address these challenges, cadmium sulfide (CdS)/titanate hybrid was fabricated by simultaneously growing titanate and CdS and had been comprehensively characterized. The optimized CdS/titanate hybrid can power the highly selective oxidative homocoupling of amines under the irradiation of green light-emitting diodes (LEDs). Specifically, CdS with a narrow bandgap captures green light; the conduction band of titanate activates mol. oxygen (O₂). The valence band of CdS could ensure the selective oxidative homocoupling of amines in methanol (CH₃OH). The hybridization between CdS and titanate accounts for the expeditious oxidative homocoupling of amines into imines and the improved stability. Reactive oxygen species (ROS) quenching experiments and in situ ESR (EPR) tests suggest that superoxide anion (O·^-2) and benzylamine radical are intermediates en route to imines. This work highlights the viability of hybridization of dual semiconductor nanostructures in implementing visible light-powered selective conversions.

Journal of Colloid and Interface Science published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Mardjan, Muhammad Idham Darussalam published the artcileUltrasonic-assisted-synthesis of isoindolin-1-one derivatives, Recommanded Product: (2-Methoxyphenyl)methanamine, the publication is RSC Advances (2022), 12(29), 19016-19021, database is CAplus and MEDLINE.

A small library of 3-hydroxyisoindolin-1-ones were prepared from 3-alkylidenephthalides under ultrasonic irradiation This practical synthesis was featured by group tolerance, high efficiency and yields. The reaction was also performed in multigram scale and can be further extended to access other motifs of isoindolin-1-ones in a one-pot fashion.

RSC Advances published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Recommanded Product: (2-Methoxyphenyl)methanamine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem