Tag: M.W=100-150

Han, Xiaocui published the artcileNovel Polymers with Ultrapermeability Based on Alternately Planar and Contorted Units for Gas Separation, Name: 1,2-Dimethoxybenzene, the publication is ACS Materials Letters (2022), 4(1), 61-67, database is CAplus.

Polymers of intrinsic microporosity (PIMs) have been the potential candidates as gas separation membrane materials, because of their high permeability and good processing. Here, three PIMs (PIM-ABAs) with ultrahigh permeability are reported; these are significantly more permeable than the PIM-1 and other PIMs reported and do not lose high selectivity and good processing merit. The introduction of large and rigid planar units alternatively contorted units suppresses the compact packing of polymer chains, resulting in the hierarchical porosity range of 0.5-4.0 nm. The presence of larger pores is responsible for promoting permeability. PIM-ABA-OMEN demonstrates the optimal CO₂ permeability (16 736 barrer), which is 3.95 times more than PIM-1 (4234 barrer) with equivalent gas selectivity and PIM-ABA-EN exhibits the promotion of both permeability and selectivity. After being aged for 186 days, PIM-ABAs still showed the CO₂ permeability above 8000 barrer, which is almost as 2 times greater than that of unaged PIM-1. This work provides a new strategy for the preparation of PIMs with enhanced gas separation performance.

ACS Materials Letters published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gao, Hui published the artcileElectrochemical benzylic C-H arylation of xanthenes and thioxanthenes without a catalyst and oxidant, Formula: C8H10O2, the publication is Organic Chemistry Frontiers (2022), 9(7), 1911-1916, database is CAplus.

A catalyst-free and oxidant-free C-H arylation of xanthenes and thioxanthenes I (R¹ = H, Me, OH, Cl, etc.; R² = H, OMe; R³R⁴ = -CH=CH-CH=CH-; X = O, S) using electrochem. has been developed, which affords a number of cross-coupling products II (R⁵ = 4-methoxyphenyl, 4-methoxy-3-methylphenyl, 4-methoxy-3,5-dimethylphenyl, 2H-1,3-benzodioxol-5-yl, etc.) in moderate to good yields. This method is atom- and step-economical as it uses cheap and easily available arenes and heteroarenes as partners directly and the C(sp²)-H/C(sp³)-H type cross-coupling reaction.

Organic Chemistry Frontiers published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, HPLC of Formula: 91-16-7, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Qingyu published the artcileHypervalent Chalcogenonium…π Bonding Catalysis, Computed Properties of 91-16-7, the publication is Angewandte Chemie, International Edition, database is CAplus and MEDLINE.

A proof-of-concept study of hypervalent chalcogenonium…π bonding catalysis was performed. A new catalytic strategy using 1,2-oxaselenolium salts as chalcogen bond donors and alkenes as chalcogen bond acceptors is described. The feasibility of this concept is demonstrated by the use of trisubstituted selenonium salts in the metal-free catalytic hydrofunctionalization and polymerization of alkenes via unconventional seleniranium ion-like intermediates. The results indicate that counter anions have a significant effect on the catalysis based on hypervalent chalcogenonium…π bonding interactions.

Angewandte Chemie, International Edition published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C7H5Cl2NO, Computed Properties of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Das, Amrita published the artcileRh(II)-Catalyzed C-H Alkylation of Benzylamines with Unactivated Alkenes: The Influence of Acid on Linear and Branch Selectivity, HPLC of Formula: 6850-57-3, the publication is Organic Letters (2021), 23(11), 4273-4278, database is CAplus and MEDLINE.

The Rh-catalyzed C-H alkylation of benzylamine derivatives 2RC₆H₄CH₂NHC(O)R¹ (R = Me, methoxy, trifluoromethyl; R¹ = pyridin-2-yl) and I (X = H) with unactivated 1-alkenes R²HC=CH² (R² = pentyl, cyclohexylmethyl, 4-(acetyloxy)butyl, etc.) that proceeds via a picolinamide directing group is reported. The crucial role of an acid additive in this transformation is confirmed. Aromatic acids showed high linear selective products e.g., N-(2-heptyl-6-methylbenzyl)picolinamide, and aliphatic acids provided branched alkylation products e.g., N-(2-(hexan-2-yl)-6-methylbenzyl)picolinamide as the major product. The reaction has a broad scope for benzylamines and alkenes. Deuterium labeling experiments suggest that a Rh-carbene intermediate is involved in the case of linear product formation. A different reaction pathway, however, appears to be involved in the case of branched alkylation products, and this pathway also appeared to be a minor pathway in linear-selective reactions.

Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, HPLC of Formula: 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Das, Amrita published the artcileRh(I)-catalyzed imine-directed C-H functionalization via the oxidative [3+2] cycloaddition of benzylamine derivatives with maleimides, Application In Synthesis of 6850-57-3, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(8), 1123-1126, database is CAplus and MEDLINE.

The Rh(I)-catalyzed imine-directed oxidative [3+2] cycloaddition of benzylamines derivatives with maleimides for synthesis of pyrrolopyrroles I [R = Ph, 2-thienyl, cyclohexyl, etc.; R¹ = H, Me, Bn, etc.] was reported. A wide range of both benzylamines derivatives and maleimides was applicable to the reaction. A one-pot three component strategy using benzylamines, 2-pyridinecarboxaldehyde and maleimides was successfully achieved. Mechanistic studies including deuterium labeling experiments suggested that a zwitterionic intermediate was formed and was a key intermediate through the Rh-catalyzed activation of a benzylic C(sp³)-H bond of the imine.

Chemical Communications (Cambridge, United Kingdom) published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Application In Synthesis of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Hung, Chang-Mao published the artcileSuppression of polycyclic aromatic hydrocarbon formation during pyrolytic production of lignin-based biochar via nitrogen and boron co-doping, Category: ethers-buliding-blocks, the publication is Bioresource Technology (2022), 127246, database is CAplus and MEDLINE.

Polycyclic aromatic hydrocarbons are toxic byproducts of biochar production The effects of pyrolysis atm. (i.e., N₂ and CO₂) and temperature (i.e., 300-900 °C) and element doping (i.e., N, B, O, and S) on the production of sixteen high priority polycyclic aromatic hydrocarbons in lignin-based biochar was investigated. N₂ atmosphere at 300 °C produced the highest total polycyclic aromatic hydrocarbon content (1698 ± 50 ng/g). Polycyclic aromatic hydrocarbon formation decreased with increase in temperature (31 ± 15 ng/g at 900 °C). CO₂ atmosphere significantly decreased yield of polycyclic aromatic hydrocarbons. The effects of heteroatom doping on polycyclic aromatic hydrocarbon formation were investigated for the first time in the pyrolysis synthesis of lignin-based biochar. N-, B-, O, N-B-, and N-S-doping of biochar reduced polycyclic aromatic hydrocarbon formation by 90, 85, 87, 97, and 89%, resp. Results bring new insights into the role of heteroatom-doping and pyrolysis conditions in controlling polycyclic aromatic hydrocarbon formation in biochars.

Bioresource Technology published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Guo, Ge published the artcileCatalytic depolymerization of Kraft lignin towards liquid fuels over bifunctional molybdenum oxide based supported catalyst, Application of 1,2-Dimethoxybenzene, the publication is Fuel (2021), 121599, database is CAplus.

Catalytic depolymerization of Kraft lignin towards valuable liquid fuels and monomeric phenols has been a significant and extremely attractive target, but it remains a great challenge. Herein, we report a catalytic system consisted of bifunctional molybdenum oxide based supported catalyst for catalytic lignin hydroconversion into alkylated benzenes and phenols. In the meantime, the achieved yield of liquid product was 95% and petroleum ether extracted product was 65% at 300°C for 12 h over 20%MoO_x/ZIF-8@ZIF-67 catalyst. The calorific value was increased from 25.66 MJ/ Kg to 34.31 MJ/Kg. The characterization studies show the incorporation of MoOx species leads to the synergy between redox sites and acid sites. The product anal. and catalytic studies demonstrate its synergism to promote catalytic cleavage of C-O linkages via the coupled hydrodeoxygenation and alkylation reaction. The reasonable catalytic mechanism and redox cycle route of catalyst indicate that the cooperative catalytic system paves the way for high-efficiency waste lignin utilization.

Fuel published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Application of 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Monopoli, Antonio published the artcileA new expeditious synthesis of the core scaffold of salvianolic acid F trough a one-pot sequential Heck coupling catalyzed by palladium nanoparticles in ionic liquids, SDS of cas: 91-16-7, the publication is Journal of Organometallic Chemistry (2022), 122193, database is CAplus.

A new expeditious synthesis of tetra-Me salvianolic acid F (I) is presented. Starting from the naturally occurring veratrole, the target mol. is easily obtained in a one-pot mode via a sequential double Heck coupling catalyzed by palladium nanoparticles dispersed in ionic liquids The present method involves the chemoselective displacement of two different halogen atoms present on the veratrole ring and limits the need for tedious exptl. procedures. A 66% of overall yield can be achieved, that represents, as far as we know, one of the best results present in the literature, until now. This protocol can also open the way for the synthesis of unnatural salvianolic-like compounds with potential bioactivity.

Journal of Organometallic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Felipe, Josyelen L. published the artcileAnti-inflammatory, ulcerogenic and platelet activation evaluation of novel 1,4-diaryl-1,2,3-triazole neolignan-celecoxib hybrids, Category: ethers-buliding-blocks, the publication is Bioorganic Chemistry (2022), 105485, database is CAplus and MEDLINE.

This study reports the synthesis of novel neolignans-celecoxib hybrids and the evaluation of their biol. activity. Analogs 8-13 (L13-L18) exhibited anti-inflammatory activity, inhibited glycoprotein expression (P-selectin) related to platelet activation, and were considered non- ulcerogenic in the animal model, even with the administration of 10 times higher than the dose used in reference therapy. In silico drug-likeness showed that the analogs are compliant with Lipinskis rule of five. A mol. docking study showed that the hybrids 8-13 (L13-L18) fitted similarly with celecoxib in the COX-2 active site. According to this data, it is possible to infer that extra hydrophobic interactions and the hydrogen interactions with the triazole core may improve the selectivity towards the COX-2 active site. Furthermore, the mol. docking study with P-selectin showed the binding affinity of the analogs in the active site, performing important interactions with amino acid residues such as Tyr 48. Whereas the P-selectin is a promising target to the design of new anti-inflammatory drugs with antithrombotic properties, a distinct butterfly-like structure of 1,4-diaryl-1,2,3-triazole neolignan-celecoxib hybrids synthesized in this work may be a safer alternative to the traditional COX-2 inhibitors.

Bioorganic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem