Suram, Dinesh team published research in AAPS PharmSciTech in 2022 | 111-90-0

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Safety of Diethylene Glycol Monoethyl Ether

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Safety of Diethylene Glycol Monoethyl Ether.

Suram, Dinesh;Veerabrahma, Kishan research published 《 Design and Development of Solid SMEDDS and Liquisolid Formulations of Lovastatin, for Improved Drug Dissolution and In vivo Effects-a Pharmacokinetic and Pharmacodynamic Assessment》, the research content is summarized as follows. Lovastatin (Lov) is a lipid-lowering agent, with 5% bioavailability (BA) due to extensive first pass metabolism and poor solubility To enhance dissolution and in vivo effects, Lov solid self microemulsifying drug delivery system (SMEDDS) and liquisolid systems were developed and evaluated to select superior one. Solubilities were determined in oils, surfactants, and cosurfactants. Ternary phase diagrams were constructed and selected the one which showed maximum emulsion zone. In vitro dissolution, DSC, SEM and PXRD studies were used to characterize the developed formulations. In vivo studies were conducted on optimal formulations in wistar rats. Based on solubilities, Capmul PG8 and Capmul MCM were preferred as oils, Labrasol and Transcutol P as surfactant and cosurfactant. Here, Syloid XDP carrier showed better adsorption capacity among others, hence was used in optimal solid SMEDDS (SX) and liquisolid (LS) formulations. Dissolution study results showed significant improvement in release when compared to pure drug. DSC, SEM, and PXRD results indicated the loss of drug crystallinity in optimal formulations. In pharmacokinetic (PK) study, SX and LS showed 2.57 and 1.43 fold improvements in AUC, when compared to that of coarse suspension (CS). In pharmacodynamic (PD) study, hyperlipidemia was induced by Triton X-100. CS and LS treatments showed a decline in hyperlipidemic levels at 4 h. But, SX-treated group showed early onset of decline at 2 h. Further, the duration of anti-hyperlipidemia was at least 12 h extra when compared to CS and LS. This study confirmed the superiority of SX over LS in PK and PD effects.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Safety of Diethylene Glycol Monoethyl Ether

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Schmied, Fabian-Pascal team published research in AAPS PharmSciTech in 2022 | 111-90-0

Name: Diethylene Glycol Monoethyl Ether, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Name: Diethylene Glycol Monoethyl Ether.

Schmied, Fabian-Pascal;Bernhardt, Alexander;Engel, Andrea;Klein, Sandra research published 《 A Customized Screening Tool Approach for the Development of a Self-Nanoemulsifying Drug Delivery System (SNEDDS)》, the research content is summarized as follows. The present study focused on establishing a novel, (pre-)screening approach that enables the development of promising performing self-nanoemulsifying drug delivery systems (SNEDDSs) with a limited number of experiments The strategic approach was based on first identifying appropriate excipients (oils/lipids, surfactants, and co-solvents) providing a high saturation solubility for lipophilic model compounds with poor aqueous solubility Excipients meeting these requirements were selected for SNEDDS development, and a special triangular mixture design was applied for determining excipient ratios for the SNEDDS formulations. Celecoxib and fenofibrate were used as model drugs. Formulations were studied applying a specific combination of in vitro characterization methods. Specifications for a promising SNEDDS formulation were self-imposed: a very small droplet size (< 50 nm), a narrow size distribution of these droplets (PDI < 0.15) and a high transmittance following SNEDDS dispersion in water (> 99% in comparison with purified water). Excipients that provided a nanoemulsion after dispersion were combined, and ratios were optimized using a customized mapping method in a triangular mixture design. The best performing formulations were finally studied for their in vitro release performance. Results of the study demonstrate the efficiency of the customized screening tool approach. Since it enables successful SNEDDS development in a short time with manageable resources, this novel screening tool approach could play an important role in future SNEDDS development.

Name: Diethylene Glycol Monoethyl Ether, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shakeel, Faiyaz team published research in Physics and Chemistry of Liquids in | 111-90-0

Reference of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Reference of 111-90-0.

Shakeel, Faiyaz;Alshehri, Sultan;Ghoneim, Mohammed M.;Martinez, Fleming;Pena, Maria.;Jouyban, Abolghasem;Acree, William E. research published 《 Solubility of tadalafil in aqueous mixtures of Transcutol and PEG 400 revisited: correlation, thermodynamics and preferential solvation》, the research content is summarized as follows. Mole fraction solubilities of tadalafil (3) in aqueous mixtures of Transcutol and PEG 400 at temperatures from 298.15 to 333.15 K were analyzed following Hildebrand solubility parameters. Cosolvency models for representing tadalafil solubility at various temperatures were also provided for correlation/prediction purposes. Apparent thermodn. quantities for tadalafil dissolution processes were calculated based on van′t Hoff and Gibbs equations. Non-linear enthalpy-entropy compensation was observed for tadalafil transfer from more polar to less polar solvent systems. Preferential solvation parameters of tadalafil at 298.15 and 313.15 K were determined by means of the inverse Kirkwood-Buff integrals (IKBI). Tadalafil is preferentially solvated by water in water-rich mixtures of Transcutol but preferentially solvated by Transcutol in mixtures of 0.12 < x1 < 1.00. In the former case, this result could be due to hydrophobic hydration around the non-polar moieties of tadalafil. Otherwise, tadalafil is preferentially solvated by PEG 400 in all the aqueous mixtures

Reference of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shamsi, Ali team published research in Journal of Molecular Structure in 2022 | 111-90-0

Category: ethers-buliding-blocks, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Category: ethers-buliding-blocks.

Shamsi, Ali;Hashemian, Saeedeh research published 《 Structural, magnetic and adsorptive properties of nano spinel of cobalt aluminate doped with nickel for Cr(VI) removal》, the research content is summarized as follows. Nanocrystallines of cobalt aluminate spinel doped with Nickel (MAl2O4; M = Co2+, Ni2+) were synthesized by sol-gel method. The MAl2O4 samples were prepared by using aluminum nitrate; cobalt nitrate, nickel nitrate, citric acid and diethylene glycol mono Et ether as precursor materials. The nanocrystallines spinel were characterized by Fourier transform IR spectroscopy (FTIR), X-ray diffraction(XRD), Thermal gravimetric (TGA), Scanning electron microcopy (SEM) with the energy dispersive X-ray spectroscopy (EDX) methods. The Sp. surface area of the synthesized powders was measured with a Brunauer-Emmet-Teller (BET) apparatus using N2 adsorption. According to obtained XRD patterns the formation of single phase MAl2O4 completed up 800 °C. The average crystallite′s sizes spinel and sp. surface area at 800 °C were estimated about 11.07 nm and 154 m2 g-1, resp. The results of SEM anal. show that the nanoparticles shape are as spherical shape, uniform and a little agglomerated. The magnetic behavior of spinels showed the magnetization decreased with increasing nickel ions. Adsorption of Cr(VI) by as prepared spinels were considered. The highest percent of Cr(VI) adsorption was occurred at contact time of 45 min, pH 7.0, and adsorbent dose of 2 g L-1. The order of adsorption capacity of sorbent samples for Cr(VI) removal was as follow: Ni0.5Cu0.5Al2O4 >Ni0.7Cu0.3Al2O4 >Ni0.3Cu0.7Al2O4>NiAl2O4> CoAl2O4. Kinetic studies indicated that the adsorption process follows by pseudo second-order model. Thermodn. results revealed that the adsorption of Cr(VI) is endothermic, spontaneously process and feasible in the range of 298-338 K.

Category: ethers-buliding-blocks, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sharma, Monika team published research in Neurotoxicity Research in 2022 | 111-90-0

Formula: C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Formula: C6H14O3.

Sharma, Monika;Kaur, Jaswinder;Rakshe, Siddhi;Sharma, Nishant;Khunt, Dignesh;Khairnar, Amit research published 《 Intranasal Exposure to Low-Dose Rotenone Induced Alpha-Synuclein Accumulation and Parkinson′s Like Symptoms Without Loss of Dopaminergic Neurons》, the research content is summarized as follows. Epidemiol. Parkinson′s disease (PD) is associated with chronic ingestion or inhalation of environmental toxins leading to the development of motor symptoms. Though neurotoxin-based animal models played a major role in understanding diverse pathogenesis, they failed to identify the risk assessment due to uncommon route of toxin exposure. Toward this, the available neurotoxin-based intranasal (i.n.) PD models targeting olfactory bulb (OB) have demonstrated the dopaminergic (DAergic) neurodegeneration in both OB and substantia nigra (SN). Despite that, the studies detecting the alpha-synuclein (α-syn) accumulation in OB and its progression to other brain regions due to inhalation of environmental toxins are still lacking. Herein, we developed oil in water microemulsion of rotenone administered intranasally to the mice at a dose which is not detectable in blood, brain, and olfactory bulb by LCMS method. Our data reveals that 9 wk of rotenone exposure did not induce olfactory and motor dysfunction. Conversely, after 16 wk of washout period, rotenone treated mice showed both olfactory and motor impairment, along with α-syn accumulation in the OB and striatum without glial cell activation and loss of dopaminergic neurons. The results depict the progressive nature of the developed model and highlight the role of α-syn in PD like pathol. or symptoms. Together, our findings suggest the adverse consequences of early exposure to the environmental toxins on the olfactory system for a shorter period with relevance to the development of synucleinopathy or Parkinson′s disease in its later stage.

Formula: C6H14O3, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sharma, Shubham team published research in Journal of Chemical & Engineering Data in 2021 | 111-90-0

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Recommanded Product: Diethylene Glycol Monoethyl Ether

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Recommanded Product: Diethylene Glycol Monoethyl Ether.

Sharma, Shubham;Sharma, Samriti;Singh, Manjeet;Singh, Jeetinder;Sharma, Meena research published 《 Density, Speed of Sound, and Viscosity for Binary Liquid Mixtures of 2-(2-Ethoxyethoxy)ethanol with Methyl Acrylate, Ethyl Acrylate, or Butyl Acrylate from T = 288.15 to 318.15 K and P = 101 kPa》, the research content is summarized as follows. In this study, the d. (ρ), speed of sound (u), and viscosity (η) of the binary liquid mixtures of an industrially important solvent 2-(2-ethoxyethoxy)ethanol (carbitol) with acrylic esters [methyl acrylate, Et acrylate, and Bu acrylate (BA)] have been measured over the entire composition range at temperatures from T = 288.15 to 318.15 K and at atm. pressure P = 101 kPa. The excess molar volume (VmE), excess isentropic compressibility (κsE), and viscosity deviations (Δη) have been calculated from the related exptl. data. All excess properties are neg. at all temperatures for all the mixtures, suggesting the compactness of binary mixture except the pos. VmE values for some concentrations of BA mixtures Deviation from ideality increases with rising temperature for both excess molar volume and excess isentropic compressibility but a decrease in deviation from ideality with temperature rise has been observed for viscosity deviations. Finally, excess properties have been fitted to the Redlich-Kister polynomial.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Recommanded Product: Diethylene Glycol Monoethyl Ether

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shehata, Tamer M. team published research in Gels in 2022 | 111-90-0

Electric Literature of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers do have nonbonding electron pairs on their oxygen atoms, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Electric Literature of 111-90-0.

Shehata, Tamer M.;Elnahas, Hanan M.;Elsewedy, Heba S. research published 《 Development, Characterization and Optimization of the Anti-Inflammatory Influence of Meloxicam Loaded into a Eucalyptus Oil-Based Nanoemulgel》, the research content is summarized as follows. The purpose of the present study was to explore the influence of a certain natural essential oil, namely eucalyptus oil, as an anti-inflammatory agent in addition to its prospective role in enhancing the action of meloxicam in reducing inflammation. As far as we know, this has been the first integration of meloxicam and eucalyptus essential oil into a nanoemulgel formulation intended for topical use. Primarily, eucalyptus oil was utilized in developing a nanoemulsion formulation incorporating meloxicam. A 22 factorial design was constructed using two independent variables (oil concentration and surfactant concentration) with two responses (particle size and % of in vitro release). One optimized formula was selected depending on the desirability function and subjected to a stability study. The optimized nanoemulsion was mixed with HPMC as a gelling agent to produce a meloxicam-loaded nanoemulgel, which was examined for its properties, stability, in vitro release and ex vivo permeation. Eventually, the anti-inflammatory activity was evaluated and compared with a placebo and corresponding gel formulation. The developed nanoemulgel revealed acceptable phys. characteristics to be applied topically. Studying of the in vitro release was conducted successfully for 6 h. The ex vivo permeation from the nanoemulgel formulations was prompted, showing an appropriate value of the steady-state transdermal flux (SSTF). As a final point, the anti-inflammatory activity of the developed nanoemulgel revealed a valued anti-inflammatory influence. Addnl., the concurrence of eucalyptus essential oil and meloxicam was assured, and their potential in combating and lowering inflammation was supported.

Electric Literature of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shen, Xiao-ran team published research in Environmental Science and Ecotechnology in 2021 | 111-90-0

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Quality Control of 111-90-0

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Quality Control of 111-90-0.

Shen, Xiao-ran;Geng, Chun-Xiang;Lv, Bing-Qian;Xu, Wei;Xu, Yi;Zhao, Hua-Zhang research published 《 Tire pyrolysis wastewater treatment by a combined process of coagulation detoxification and biodegradation》, the research content is summarized as follows. Recycling waste tires through pyrolysis technol. generates refractory wastewater, which is harmful to the environment if not disposed properly. In this study, a combined process of coagulation detoxification and biodegradation was used to treat tire pyrolysis wastewater. Organics removal characteristics at the mol. level were investigated using electrospray ionization (ESI) coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). The results showed that nearly 90% of the organic matter from the wastewater was removed through the process. Preference of the two coagulants for different classes of organics in tire pyrolysis wastewater was observed The covalently bound inorganic-organic hybrid coagulant (CBHyC) used in this work had a complementary relationship with biodegradation for the organics removal: this coagulant reduced toxicity and enhanced the biodegradation by preferentially removing refractory substances such as lignin with a high degree of oxidation (O/C > 0.3). This study provides mol. insight into the organics of tire pyrolysis wastewater removed by a combined treatment process, supporting the advancement and application of waste rubber recycling technol. It also contributes to the possible development of an effective treatment process for refractory wastewater.

111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Quality Control of 111-90-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shettar, Abhishek team published research in Journal of Drug Delivery Science and Technology in 2021 | 111-90-0

Related Products of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Related Products of 111-90-0.

Shettar, Abhishek;Shankar, Vijay Kumar;Ajjarapu, Srinivas;Kulkarni, Vijay I.;Repka, Micheal A.;Murthy, S. Narasimha research published 《 Development and characterization of Novel topical oil/PEG creams of voriconazole for the treatment of fungal infections》, the research content is summarized as follows. Voriconazole (VRC), a second generation triazole derivative emerged as a promising candidate for the treatment of fungal infections. Voriconazole is com. available as oral and i.v. formulations, however administration through these routes is associated with several side effects like hepatotoxicity, photopsia and abdominal pain. Hence, percutaneous delivery of voriconazole through creams or hydrogels would be beneficial for preventing side effects due to other routes of administration. Voriconazole may potentially undergo degradation in formulations containing water. The objective of the study was to prepare a stable biphasic semisolid formulation using oil and PEG. The melt extrusion process was used as a continuous manufacturing technique for preparation of oil/PEG cream. Formulation composition and processing conditions were optimized based on the compatibility and pre-formulation studies. The developed creams were characterized for content uniformity, viscosity and in vitro drug release. The effect of Transcutol P and camphor: menthol (1:1) on the permeation of voriconazole was evaluated by ex vivo permeation studies. The voriconazole in oil/PEG formulation (93.44 ± 1.59%) were stable for 3 mo compared to control voriconazole hydrogel formulation (10.67 ± 0.03%) at 25°C (60% RH). The formulation with Transcutol P used as a permeation enhancer increased voriconazole permeation 9 folds compared to formulation without permeation enhancer. In conclusion, a stable oil/PEG voriconazole cream was successfully developed using continuous manufacturing process and can be used as alternate for i.v./oral voriconazole for treatment of fungal skin infections.

Related Products of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Silva, Sara team published research in Molecules in 2022 | 111-90-0

Quality Control of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Quality Control of 111-90-0.

Silva, Sara;Marto, Joana;Goncalves, Lidia M.;Fernandes, Henrique S.;Sousa, Sergio F.;Almeida, Antonio J.;Vale, Nuno research published 《 Development of Neuropeptide Y and Cell-Penetrating Peptide MAP Adsorbed onto Lipid Nanoparticle Surface》, the research content is summarized as follows. Functionalization of nanoparticles surfaces have been widely used to improve diagnostic and therapeutic biol. outcome. Several methods can be applied to modify nanoparticle surface; however, in this article we focus toward a simple and less time-consuming method. We applied an adsorption method on already formulated nanostructured lipid carriers (NLC) to functionalize these nanoparticles with three distinct peptides sequences. We selected a cell-penetrating peptide (CPP), a lysine modified model amphipathic peptide (Lys(N3)-MAP), CPP/drug complex, and the neuropeptide Y. The aim of this work is to evaluate the effect of several parameters such as peptide concentration, different types of NLC, different types of peptides, and incubation medium on the physicochem. proprieties of NLC and determine if adsorption occurs. The preliminary results from zeta potential anal. indicate some evidence that this method was successful in adsorbing three types of peptides onto NLC. Several non-covalent interactions appear to be involved in peptide adsorption with the possibility of three adsorption peptide hypothesis that may occur with NLC in solution Moreover, and for the first time, in silico docking anal. demonstrated strong interaction between CPP MAP and NPY Y1 receptor with high score values when compared to standard antagonist and NPY.

Quality Control of 111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., 111-90-0.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem