Tag: M.W=150-200

Olasehinde, Tosin A. published the artcileCholinesterase inhibitory activity, antioxidant properties, and phytochemical composition of Chlorococcum sp. extracts, Computed Properties of 121-00-6, the main research area is Chlorococcum dichloromethane phytol neophytadiene cholinesterase inhibitor antioxidant; Alzheimer’s disease; Chlorococcum sp. | Microalgae; anticholinesterase activity; antioxidant activity.

In this study, Chlorococcum sp. was investigated for its cholinesterase inhibitory potentials and antioxidant activity. The algal sample was cultivated, harvested, and extracted sequentially using n-hexane, dichloromethane, and ethanol. The extracts were characterized using Fourier transmission infra-red (FTIR) and Gas Chromatog.-Mass Spectrometry. The metal chelating, radical scavenging activities, as well as anticholinesterase potentials of the algal extract, was also investigated. FTIR characterization of the microalgal biomass revealed the presence of phenolic compounds, alkaloids, polysaccharides, and fatty acids. The extracts showed the presence of phytol, neophytadiene, butylated hydroxyl toluene, and 3-tert-butyl-4-hydroxyanisole. The ethanol extract showed the highest DPPH (IC50 = 147.40μg/mL) and OH (IC50 = 493.90μg/mL) radical scavenging and metal chelating (IC50 = 83.25μg/mL) activities. Similarly, the ethanol extract (IC50 = 13.83μg/mL) exhibited the highest acetylcholinesterase inhibitory activity, while the dichloromethane extract showed the highest butyrylcholinesterase inhibitory activity. All the extracts exhibited antioxidant properties and inhibitory effects against butyrylcholinesterase and acetylcholinesterase; however, ethanol extracts showed better activity. Practical applications : Biomass obtained from some microalgal species is commonly used as dietary supplements and nutraceuticals due to the presence of high-valued products. However, the antioxidant and anticholinesterase activities of biomass from Chlorococcum sp. have not been explored. Chlorococcum sp. extracts contain some antioxidants such as 3-tert-Butyl-4-hydroxyanisole, butylated hydroxytoluene, phytol, and neophytadiene. Characterization of the extracts also revealed the presence of phenolic compounds, polysaccharides, and fatty acids. These compounds may contribute to the observed antioxidant and anticholinesterase activities of Chlorococcum sp. The result of this study suggests that Chlorococcum sp. may contain some nutraceuticals which could be used as antioxidants and cholinesterase inhibitors.

Journal of Food Biochemistry published new progress about Antioxidants. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Computed Properties of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Grover, Madhuri published the artcilePhytochemical Screening, antioxidant Assay and Cytotoxic Profile for Different Extracts of Chrysopogon zizanioides Roots, Formula: C11H16O2, the main research area is Chrysopogon root extract antioxidant cytotoxic; antioxidant; cancer; chemotherapy; cytotoxicity; vetiver.

The Chrysopogon zizanioides plant possesses multiple traditional uses, especially in therapeutics, but only a few articles have reported its biol. activity. Hence, the present study was planned to explore the phytochem. constituents, cytotoxic potential, radical scavenging activity, and GC/MS (Gas chromatog. & Mass spectrometry) anal. of the vetiver root extracts The roots extracted with different solvents exhibited more significant phytochem. constituents in polar solvents in comparison to non-polar ones, favoring the extraction of a greater number of components in highly polar solvents. All the extracts were tested for their cytotoxicity using SRB (Sulforhodamine B) assay. They confirmed ethanolic extract as a potent extract with GI50 56±0.5 μg/mL in oral cancer (SCC-29B) along with no cytotoxicity in healthy cells (Vero cells), making it a safer therapeutic option in comparison to standard Adriamycin. This extract was also analyzed for its antioxidant potential by DPPH (1,1-Diphenyl-2-picrylhydrazyl) assay with IC50 value 10.73 μg/mL, which was quite comparable to Ascorbic acid having IC50 value 4.61 μg/mL. The quant. anal. of ethanolic extract exhibited 107 compounds amongst which Khusenic acid, Ascorbic acid, Junipen, gamma-Himachalene, alpha-Guaiene were the majorly occurring compounds that can be explored further for their cytotoxic activity.

Chemistry & Biodiversity published new progress about Antioxidants. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Formula: C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Kohno, Yoshiumi published the artcileEffect of stabilizers on the stability enhancement of naturally occurring dye incorporated in clay interlayer, Application of 4-Hydroxy-3-tert-butylanisole, the main research area is phenolic compound natural dye clay interlayer stabilizer stability.

Naturally occurring dyes are expected as an environmentally- and eco-friendly colorant. The limitation of the usage by their low stability can partially be solved by the incorporation into inorganic host materials. However, the stability of the dye-inorganic host composites has still been insufficient. In this study, further stability enhancement of the dye composite is tried by adding several phenolic compounds as a radical scavenging stabilizer. The photostability and thermal stability of β-carotene incorporated in the organoclay interlayer is successfully improved especially when the stabilizer mols. can be efficiently intercalated together with the β-carotene. For rather slow rate of degradation, the phenolic compounds having hindered structure showed higher stabilization effect, whereas for the fast degradation, non-hindered phenols showed high efficiency. The difference in the effectiveness as a stabilizer can be explained both by the stability of the intermediate phenoxy radical species and by the steric hindrance. As a stabilizer of environmentally friendly dye composite materials, naturally occurring gallic acid and vanillic acid are the most preferrable compounds for the present composites.

Journal of Physics and Chemistry of Solids published new progress about Antioxidants. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Application of 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yahaya, W. A. W. published the artcileCharacterization of semi-refined carrageenan film plasticized with glycerol incorporated with Persicaria minor extract as antioxidant additives, Application In Synthesis of 121-00-6, the main research area is Persicaria antioxidant carrageenan glycerol.

Semi refined carrageenan plasticized with 0.9% glycerol (G) added with Persicaria minor (PM) extract and 0.4% BHA as antioxidant additives for the development of active packaging films. The extraction of PM using 75% (volume/volume) ethanol: water ratio showed the highest polyphenol content with 176.80±4.37 Gallic Acid Equivivalent (GAE)/L sample and 94.65±0.17% inhibition analyzed using DPPH antioxidant activity (p<0.05). The characterization of SRC-G based film containing 0.4, 1.0, 1.5 and 2.0% PM and BHA were observed using FTIR, mech. and phys. properties of the treated films. FTIR spectrum band showed insight anal. of PM extract and BHA with carrageenan. SRC film plasticized with glycerol improved overall phys. properties including thickness, barrier and flexibility and increased tensile strength and elongation at break compared to the SRC film only (p<0.05). The active films with PM extracts (2.0% weight/weight) exhibited good mech. properties with tensile strength and elongation at break with 28.01±0.17 and 37.37±0.29. The addnl. of PM extract in SRC films increased the moisture content and opacity as proportionally to the concentration of PM extracts Film treated with 2.0% PM showed lowest value of films solubility compare to all sample (p<0.05). Hence, the characterization measurement of SRC based films demonstrated great potential with natural extract formulation for the development of active film packaging for food products. IOP Conference Series: Materials Science and Engineering published new progress about Antioxidants. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Application In Synthesis of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lin, Wei-Chuwan published the artcileDependence of vicinal H-H coupling constants in substituted ethanes on the potential function characteristics to internal rotation. Application to A2B2 PMR spectrum of nonsymmetrical 1,2-disubstituted ethanes, Application In Synthesis of 622-86-6, the main research area is nonsym disubstituted ethanes NMR; PMR nonsym disubstituted ethanes; coupling constant disubstituted ethanes; constant coupling disubstituted ethanes; disubstituted ethanes coupling constant; ethanes disubstituted coupling constant.

Based on rotational averaging, a theory governing the change of the vicinal coupling parameters L and N in the A2B2 PMR spectra of nonsym. 1,2-disubstituted ethanes, as evidenced in the studies of substituent effect and solvent effect, has been developed in terms of the potential function characteristics to internal rotation about the C-C bond. By taking the average over the entire period of dihedral angle with respect to an appropriate potential function for internal rotation of the compound, a refined Karplus equation for the vicinal H-H coupling constant as a function of dihedral angle, J = A cosΦ2 + B cosΦ + C, could yield the expression for L/A and (or) N/A in terms of hyperbolic Bessel functions which describes an explicit functional dependence of L and (or) N on both the ethane barrier and the maximum dipole interaction potential between the 2 bonds C-X and C-Y. These expressions enable one to determine the phys. parameters related to internal rotation upon measurement of L and (or) N from NMR spectrum. The determined energy difference between rotamers for several 1,2-disubstituted ethanes were found in good agreement with the literature values. Solvent effect on the A2B2 PMR spectrum is discussed on the light of the theory. The NMR exptl. relation N ∓ 1/3 |L| = A was derived from the above expressions. This latter relation enables one to tell whether the trans or the gauche isomer is more stable for the given compound from measurement on N and L with respect to the neat sample or in the medium of various solvents, and it also enables one to evaluate the value of A for each given compound

Journal of Chemical Physics published new progress about Conformation. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Application In Synthesis of 622-86-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Morgan, David L. published the artcileEnd-Quenching of TiCl4-Catalyzed Quasiliving Polyisobutylene with Alkoxybenzenes for Direct Chain End Functionalization, Product Details of C8H9ClO, the main research area is polyisobutylene alkoxybenzene end quenching.

Alkoxybenzenes were used to end-quench TiCl4-catalyzed quasiliving isobutylene polymerizations initiated from 2-chloro-2,2,4-trimethylpentane or 5-tert-butyl-1,3-di(1-chloro-1-methylethyl)benzene at -70 °C in 40/60 (volume/volume) hexane/methyl chloride. The alkoxybenzene/chain end molar ratios were in the range 2.5-4. Effective alkoxybenzene quenchers included those with simple alkyl groups, such as anisole and isopropoxybenzene, haloalkyl tethers, such as (3-bromopropoxy)benzene and (2-chloroethoxy)benzene, and even those with hydroxyl and amine functionality, such as 4-phenoxy-1-butanol and 6-phenoxyhexylamine. Alkylation was generally quant. and occurred exclusively in the para position; multiple alkylations on the same alkoxybenzene were not observed The alkylation reactions were tolerant of temperatures ranging from -70 to -30 °C and were unimpeded by the presence of endo- or exo-olefin termini. In situ cleavage of the ether linkage of anisole and isopropoxybenzene termini allowed single pot syntheses of phenol-terminated polyisobutylenes.

Macromolecules (Washington, DC, United States) published new progress about Polymerization. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Product Details of C8H9ClO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Maceira, Alba published the artcileOccurrence of plastic additives in outdoor air particulate matters from two industrial parks of Tarragona, Spain: Human inhalation intake risk assessment, SDS of cas: 121-00-6, the main research area is plastic additive industrial park human inhalation intake; Air particulate matter samples; Gas chromatography-mass spectrometry; Human inhalation exposure; Outdoor air; Plastic additives.

Plastic additives include several kinds of chems. that are added to the polymer matrix to improve the final product quality and prevent deterioration effects. They are used in a large quantity of materials, so their presence in the environment is expected. This study has developed and validated a method based on gas chromatog.-mass spectrometry after pressurized liquid extraction to determine sixteen plastic additives including UV-stabilizers, aromatic and phenolic antioxidants and some of their degradation products in particulate matter (PM10) from outdoor air. Apparent recoveries were above 85% for most of compounds and low detection limits (pg m-3) were achieved. This is the first study to determine these types of contaminant in the PM10 of outdoor air from two locations surrounded by different industries. Various compounds were found in almost all samples; BHT, BHT-Q, 2,4-DTBP, BHT-CHO, UV320, UV328, Irgafos168 and Iragonx1076, with concentrations ranging from < MQL to 2860 pg m-3. Estimated daily intakes (EDIs) via ambient inhalation were calculated for each polymer additive and for different subpopulation groups classified by age. Two possible exposure scenarios (low, based on geometric mean, and high, 95th percentile) were simulated, and 0.51 ng kg-1bw day-1 was the EDI in the worst case scenario for children. Journal of Hazardous Materials published new progress about Air pollution. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, SDS of cas: 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nagarajan, K. published the artcileQuest for anthelmintic agents. Part IV. Some analogs of bephenium and tetramisole, Formula: C8H9ClO, the main research area is anthelmintic bephenium tetramisole analog preparation.

Five biphenium analogs [N-(2-benzimidazolyl)methyl-N,N-dimethyl-N-(2-phenoxy)ethylammonium iodide, 2-(N-benzyl-8-quinoliniumoxy)ethyl-N,N-dimethyl-N-benzylammonium dibromide, I, II, and III and 2 tetramisole analogs [6-(2-benzothiazolyl)-2,3-dihydroimidazo[2,1-b]thiazole (IV) and 5-(2-benzothiazolyl[-2,3-dihydrothiazolo[2,1-a]imidazole] were prepared E.g., IV was prepared from 2-bromoacetylbenzothiazole, first by reaction with 2-aminothiazoline followed by heating the 3-(2-benzothiazolylcarbonylmethyl)thiazolidine-2-imine with dilute HBr. None of the 7 compounds were active against Necatur americanus infection in hamsters.

Indian Journal of Pharmaceutical Sciences published new progress about Anthelmintics. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Formula: C8H9ClO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Runtong published the artcileTetraphosphite ligand for ultrafast isomerization-hydroformylation of C4 raffinate under mild conditions, Recommanded Product: 4-Hydroxy-3-tert-butylanisole, the main research area is raffinate tetraphosphite ligand isomerization hydroformylation ultrafast.

Ultrafast linear selective isomerization-hydroformylation (ISO-HF) tandem reaction under mild conditions remains a challenge. Herein, a novel tetraphosphite ligand (TBTP) and its application in ISO-HF of C4 Raffinate were reported. Based on a biphenol-2,2′,6,6′-tetraol with sterically demanding tert-Bu substituents, TBTP can be readily prepared by the reaction of biphenyl phosphorchloridite and tetraol in kilogram scale. The structural and coordinating features of this ligand and its rhodium complex were studied by XRD, NMR and DFT calculations This tetraphosphite ligand showed high turnover frequencies and regioselectivities in the rhodium-catalyzed ISO-HF of trans-, cis-2-butene. Such hydrolytically stable ligand was successfully applied in the ISO-HF of etherified C4 feed under a mild condition (65°C, 7 bar syngas, TOF up to 1574 h-1, ∼95% linear selectivity). An over-14-day durability test that was operated in two 5-L continuously stirred-tank reactors (CSTRs) in series delivered 79 kg n-valeraldehyde for the manufacture of C10 plasticizer DPHP.

Journal of Catalysis published new progress about Crystallinity. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Recommanded Product: 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Masuda, Koichiro published the artcileAerobic Dehydrogenative Coupling of Naphthols and Phenols with a Ru(OH)x/Al2O3 Catalyst under Continuous-Flow Conditions, SDS of cas: 121-00-6, the main research area is binaphthol biphenol preparation green chem continuous flow; naphthol phenol aerobic dehydrogenative coupling alumina ruthenium hydroxide catalyst.

Dehydrogenative coupling reactions of naphthols and phenols were achieved with a heterogeneous catalyst, alumina-supported ruthenium hydroxide (Ru(OH)x/Al2O3), using continuous-flow conditions and aerobic oxygen as the sole oxidant. The reactions were operated continuously for more than 16 h with good reactivity and selectivity. The Ru catalyst could be recycled at least three times by a simple online washing/activation procedure without depackaging the catalyst cartridge. The reaction provided binaphthols and biphenols as valuable products for synthetic purpose and functional materials, while an over-oxidized quinone was obtained with 2,6-Di-tert-butylphenol; combining this reaction with catalytic hydrogenation under continuous-flow conditions enabled smooth conversion of quinone to the 4,4′-biphenol derivative, which is a member of an important class of compounds for liquid crystals, engineering plastics, and other functional materials.

ChemistrySelect published new progress about Flow reactors. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, SDS of cas: 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem