Tag: M.W=150-200

Wu, Haijun published the artcilePromoting the conversion of poplar to bio-oil based on the synergistic effect of alkaline hydrogen peroxide, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Renewable Energy (2022), 107-117, database is CAplus.

The synergistic catalysis effect of NaOH and H₂O₂ on the hydrothermal liquefaction (HTL) of poplar was investigated and compared to the NaOH or H₂O₂ catalyzed HTL at different temperatures and 30 min residence time. GC-MS, GPC, FT-IR, HPLC and TGA were used to comprehensively characterize the phys. and chem. properties of liquefied products (bio-oil, lignin and solid residue). The results showed that the highest total bio-oil yield (70.65%) was obtained at 280°C with NaOH (35 g/L)/H₂O₂ (30 g/L) as catalysts. The average mol. weight and polydispersity index (PDI) were found to be lower compared to that from other conditions. As the NaOH concentration was increased, the bio-oil yield was improved. The concentration of H₂O₂ for the optimal synergistic effect was observed to be 30 g/L. GC-MS anal. showed that the bio-oil obtained by NaOH (35 g/L)/H₂O₂ (30 g/L) was characterized with the lowest N content. The synergistic effect promoted the higher production selectivity of o-xylene and p-xylene in the bio-oil.

Renewable Energy published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C6H10O7, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wang, Weijin published the artcileOxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics, Recommanded Product: 2-Methoxynaphthalene, the publication is Nature Communications (2021), 12(1), 3873, database is CAplus and MEDLINE.

Herein, TEMPO (2,2,6,6-tetramethylpiperidine nitroxide) and its derivatives are disclosed as active catalysts for electrophilic halogenation of olefins e.., prop-1-en-1-ylbenzene, alkynes R¹CCR² (R¹ = octyl, Ph; R² = H, Me, n-Bu, Ph), and aromatics R³H (R³ = 3-(carboxymethyl)-4-methoxybenzen-1-yl, 2-[ethoxy(oxo)methane]-1H-indol-3-yl, 5-phenylthiophen-2-yl, etc.). These catalysts are stable, readily available, and reactive enough to activate haleniums including Br⁺, I⁺ and even Cl⁺ reagents. This catalytic system is applicable to various halogenations including haloarylation of olefins or dibromination of alkynes, which were rarely realized in previous Lewis base catalysis or Lewis acid catalysis. The high catalytic ability is attributed to a synergistic activation model of electrophilic halogenating reagents, where the carbonyl group and the halogen atom are both activated by present TEMPO catalysis.

Nature Communications published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C12H10FeO4, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Kang, Qi-Kai published the artcileRhodium-Catalyzed Stereoselective Deuteration of Benzylic C-H Bonds via Reversible η⁶-Coordination, Recommanded Product: 2-Isopropylanisole, the publication is Angewandte Chemie, International Edition (2022), 61(11), e202117381, database is CAplus and MEDLINE.

Practical methods of benzyl H/D exchange of various substrates [such as 1-methoxy-2-methylbenzene, 2,3-dihydrobenzofuran, cyclohexylbenzene, 3-phenyl-1-piperidin-1-yl-butan-1-one, O-acetyl dapagliflozin, etc.] with primary, secondary, or tertiary C-H bonds have been reported through a reversible η⁶-coordination strategy. A doubly cationic [Cp^CF3Rh^III]²⁺ catalyst that serves as an arenophile facilitates deprotonation of inert benzylic hydrogen atoms (pK_a>40 in DMSO) without affecting other hydrogen atoms, such as those on aromatic rings or in α-positions of carboxylate groups. Notably, the H/D exchange reactions feature high stereoretention. The potential usefulness of this method has been demonstrated by its use in deuterium labeling of ten pharmaceuticals and their analogs.

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Liu, Zhizhou published the artcileThe danger of dichloromethane in the synthesis and application of imidazole-based dyes, Application In Synthesis of 134-96-3, the publication is Dyes and Pigments (2022), 110404, database is CAplus.

In this paper, a lophine-based phenol compound (I) has been prepared and identified as an efficient chromophore for the determination of hydrogen peroxide (H₂O₂) with enzymic method. A dry chem. analytic agent was also prepared involving this compound, showing good accuracy in the determination of uric acid. However, a commonly used solvent dichloromethane (DCM) could react with this imidazole derivative when the reaction mixture was irradiated under UV (365 nm). We explored the possible mechanism and identified several byproducts caused by the acidity and UV oxidation of DCM. Caution should be taken in the synthesis and application of such imidazole-based dyes in DCM, especially when phenol group was introduced to the imidazole moiety.

Dyes and Pigments published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Application In Synthesis of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Pan, Wenjing published the artcileA mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh₂ and ^tBuOK, Application of 2-Isopropylanisole, the publication is Organic & Biomolecular Chemistry (2021), 19(35), 7633-7640, database is CAplus and MEDLINE.

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C₆H₅, 3-FC₆H₄, 2-naphthyl, etc.), R¹OCH²Ph (R¹ = C₆H₅, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R²OCH²CH=CH² (R² = C₆H₅, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh₂ and ^tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis.

Organic & Biomolecular Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Pan, Wenjing published the artcileA mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh₂ and ^tBuOK, Quality Control of 93-04-9, the publication is Organic & Biomolecular Chemistry (2021), 19(35), 7633-7640, database is CAplus and MEDLINE.

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C₆H₅, 3-FC₆H₄, 2-naphthyl, etc.), R¹OCH²Ph (R¹ = C₆H₅, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R²OCH²CH=CH² (R² = C₆H₅, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh₂ and ^tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis.

Organic & Biomolecular Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Quality Control of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ku, Conghao published the artcileOne-step construction of mesoporous cyano and sulfur co-modified carbon nitride for photocatalytic valorization of lignin to functionalized aromatics, COA of Formula: C9H10O4, the publication is Applied Surface Science (2022), 153266, database is CAplus.

Herein, mesoporous cyano and sulfur co-modified carbon nitride (MCSCN) is one-step constructed for the first time by a simple strategy using urea and trithiocyanuric acid as precursors. Trithiocyanuric acid can act as pore-fabricating units to form mesopores, meanwhile introduce cyano groups and sulfur atoms into carbon nitride. The constructed mesoporous structures effectively reduce the mass transfer resistance of macromol. lignin in the photocatalytic reaction process. The synergistic effect of the modified cyano groups and sulfur atoms significantly improves the photocatalytic valorization effect of waste lignin to functionalized aromatics As a representative of waste lignin, waste Camellia oleifera shell (WCOS) lignin can be efficently photocatalytic transformed to monophenolic compounds by MCSCN, and each gram of WCOS lignin can harvest 116.2 mg of functionalized aromatics, which is about 7 times higher than that by traditional g-C₃N₄ photocatalyst (16.7 mg/g).

Applied Surface Science published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, COA of Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Li-dong published the artcileStudy of ¹⁷O-NMR chemical shifts of substituted methylphenylether, SDS of cas: 2944-47-0, the publication is Bopuxue Zazhi (2002), 19(3), 289-292, database is CAplus.

This paper provides a equation: δ_cal = δ₀ + Δo + Δm + Δp for calculation of ¹⁷0 chem. shifts of substituted methylphenylethers. 20 Substituent parameters are gained by linear least square regression anal. The calculated results are checked regressively by 101 ¹⁷O-NMR chem. shifts of 78 substituted methylphenylethers. The confidence limit is 99.5% and calculating errors for about 90% of the compounds are less than 5 ppm (with relative errors of 0.5%).

Bopuxue Zazhi published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, SDS of cas: 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Shao, Ailong published the artcileElectrochemical Intramolecular C-H/O-H Cross-Coupling of 2-Arylbenzoic Acids, COA of Formula: C8H11BO3, the publication is Chinese Journal of Chemistry (2018), 36(7), 619-624, database is CAplus.

A synthetic protocol to lactones, e.g. I, by electro-oxidative induced C-H activation of 2-arylbenzoic acids was developed using aqueous Na₂SO₄ as a cheap and green supporting electrolyte in 30%-90% yields. This reaction could be conducted on a gram scale with a good efficiency as well as showed high utility for natural product synthesis like Sabilactone.

Chinese Journal of Chemistry published new progress about 725251-81-0. 725251-81-0 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Methoxy-5-methylphenyl)boronic acid, and the molecular formula is C7H5ClN2S, COA of Formula: C8H11BO3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ohmura, Toshimichi published the artcileIridium-Catalyzed C(sp³)-H Addition of Methyl Ethers across Intramolecular Carbon-Carbon Double Bonds Giving 2,3-Dihydrobenzofurans, Recommanded Product: 2-Isopropylanisole, the publication is Advanced Synthesis & Catalysis (2019), 361(19), 4448-4453, database is CAplus.

Intramol. addition of an O-Me C(sp³)-H bond across a carbon-carbon double bond occurs in the iridium-catalyzed reaction of Me 2-(propen-2-yl)phenyl ethers 2-MeC(=CH₂)-4-R-3-R¹-2-R²C₆HOMe (R = H, Me, Cl, t-Bu; R¹ = H, Me, MeO, CF₃; R² = H, Me, Ph, t-Bu, Br; R¹R² = CH=CH-CH=CH). The Ir/(S)-DTBM-SEGPHOS catalyst promotes the reaction efficiently in toluene at 110-135 °C to afford 3,3-dimethyl-2,3-dihydrobenzofurans I. Enantioselective C(sp³)-H addition is achieved in the reaction of Me 2-(1-siloxyethenyl)phenyl ethers 2-TBSOC(=CH₂)-4-R³-3-R⁴-2-R⁵C₆HOMe (R³ = H, Cl, t-Bu; R⁴ = H, MeO; R⁵ = H, Me, MeO, t-Bu, Cl; R⁴R⁵ = CH=CH-CH=CH), affording enantioenriched 3-hydroxy-2,3-dihydrobenzofuran derivatives II with up to 96% ee.

Advanced Synthesis & Catalysis published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem