Tag: M.W=150-200

Katariya, Ashishkumar P. published the artcileIonic Liquid Promoted Regio-Selective Synthesis of 2-Methyl amino-3-Nitro-pyrano[3,2-c]chromen-5-ones, Related Products of ethers-buliding-blocks, the publication is ChemistrySelect (2022), 7(23), e202201295, database is CAplus.

An efficient, and simple protocol for the synthesis of extremely functionalized pyrano[3,2-c]chromen-5-ones has been developed. One-pot multicomponent cyclo-condensation of 4-hydroxycoumarin, aromatic-aldehydes, and (E)-N-methyl-1-(methylthio)-2-nitroethenamine (NMSM) catalyzed by ionic liquid [(EMIM)Ac] in two different methods as methanolic mediated and at solvent free condition is described which presumably involve the Knoevenagel reaction succeeding Michael-addition and O-cyclization with elimination of methanethiol. The noteworthy features of this protocol are use of ionic liquid as catalyst, good to excellent yield, optimum reaction time with easy exptl. procedure.

ChemistrySelect published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yang, Yang published the artcileIncreasing contribution of microbial residues to soil organic carbon in grassland restoration chronosequence, Synthetic Route of 134-96-3, the publication is Soil Biology & Biochemistry (2022), 108688, database is CAplus.

Grassland restoration across the world increases soil organic carbon (SOC) sequestration which is critical for global C cycling and CO₂ removal from the atm. However, the relative importance of plant- and microbially-derived C for SOC is still an open question for temperate grasslands. Here, amino sugars and lignin phenols were used as biomarkers to investigate the relative microbial and plant residue contribution to SOC in a 30-yr (1-, 5-, 10-, 15-, 25-, 30-yr) restoration chronosequence of temperate grassland. The contribution of microbially-derived C (from 4.9 to 13 g kg^-1) to SOC was much greater than that of plant-derived C (from 1.3 to 2.3 g kg^-1). At the early stage of restoration (<15 years), grassland soils accumulated more C in the form of plant-derived C. In contrast, grassland soils at the late stage of restoration (>15 years) accumulated more microbially-derived C, and less from plant residues. These findings highlight the dominance of microbial contribution to SOC stabilization compared with plant residues. The contribution of bacteria-derived C to SOC gradually increased from 29% to 50% with progress of grassland restoration, while the contribution of fungal C to SOC decreased from 30% to 21%. Consequently, microbial residue contribution to SOC shifts from fungal and bacterial to mainly bacterial residues during grassland restoration. This shift may be due to the faster bacterial growth and a increasing living biomass during grassland restoration, leading to higher accumulation of bacterial residues. Correlation anal. and random forest models showed that belowground plant biomass, soil pH, and living microbial biomass were the main factors regulating plant-derived C. The microbially-derived C in SOC, however, was dependent on living microbial biomass, soil pH and dissolved organic C. Concluding, grassland restoration increased soil C sequestration primarily by microbial necromass (mainly bacterial necromass), and is affected by abiotic and biotic factors, as well as plant C input.

Soil Biology & Biochemistry published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C8H11BO3, Synthetic Route of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Suleman, Zubair published the artcileNeuroprotective effects of Lippia javanica (Burm.F.) Spreng. Herbal tea infusion on Lead-induced oxidative brain damage in Wistar rats, HPLC of Formula: 134-96-3, the publication is BMC Complementary Medicine and Therapies (2022), 22(1), 4, database is CAplus and MEDLINE.

Though Lippia javanica (Burm.f.) Spreng antioxidant activity has been demonstrated, its effect in protecting the brain from lead (Pb)-induced oxidative damage is unknown. This study investigated the effect of L. javanica against Pb-induced oxidative stress, inflammation, apoptosis and acetylcholinesterase activity in rats brain. L. javanica herbal tea infusion was prepared, its phytochem. constituent was revealed by liquid chromatog.-Mass spectrometer (LC-MS) and was administered simultaneously with Pb. Four groups of male Wistar rats (n = 5/group) were used: control received distilled water; Pb-acetate group received 50 mg Pb/ Kg bodyweight (bw), treatment group received 50 mg Pb/ Kg Pb-acetate + 5 mL/kg bw L. javanica and L. javanica group received 5 mL/Kg bw of L. javanica tea infusion only. After 6 wk of treatment, oxidative status, acetylcholinesterase activity, inflammation and apoptosis was assessed in brain tissue which was also histol. examined Mean brain and heart weight was reduced (p < 0.05) while liver and spleen weights were increased (p < 0.05) in Pb exposed animals but were prevented by L. juvanica treatment. Treatment with L. javanica increased (p < 0.05) overall brain antioxidant status (glutathione and superoxide dismutase activities) and reduced lipid peroxidation (p < 0.05) compared to the Pb exposed animals. Pro-inflammatory cytokine tumor necrotic factor-alpha, pro-apoptosis Bax protein and anticholinesterase activity were reduced (p < 0.05) in Pb-L. javanica treated animals compared to the Pb exposed group. Histol. examination confirmed neuroprotective effects of L. javanica as evidenced by reduced apoptosis/necrosis and inflammation-induced vacuolization and edema in the hippocampus. The L. javanica treatment alone had no detrimental effects to the rats. LC-MS anal. revealed L. javanica to be rich in phenolics. This study demonstrated that L. javanica, rich in phenolics was effective in reducing Pb-induced brain oxidative stress, inflammation, apoptosis, acetylcholinesterase activity and neuronal damage.

BMC Complementary Medicine and Therapies published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C23H43NP2, HPLC of Formula: 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Rizzo, P. V. published the artcileIdentification of aroma-active compounds in Cheddar cheese imparted by wood smoke, Related Products of ethers-buliding-blocks, the publication is Journal of Dairy Science (2022), 105(7), 5622-5640, database is CAplus and MEDLINE.

Cheddar cheese is the most popular cheese in the United States, and the demand for specialty categories of cheese, such as smoked cheese, are rising. The objective of this study was to characterize the flavor differences among Cheddar cheeses smoked with hickory, cherry, or apple woods, and to identify important aroma-active compounds contributing to these differences. First, the aroma-active compound profiles of hickory, cherry, and apple wood smokes were analyzed by solid-phase microextraction (SPME) gas chromatog.-olfactometry (GCO) and gas chromatog.-mass spectrometry (GC-MS). Subsequently, com. Cheddar cheeses smoked with hickory, cherry, or apple woods, as well as an unsmoked control, were evaluated by a trained sensory panel and by SPME GCO and GC-MS to identify aroma-active compounds Selected compounds were quantified with external standard curves. Seventy-eight aroma-active compounds were identified in wood smokes. Compounds included phenolics, carbonyls, and furans. The trained panel identified distinct sensory attributes and intensities among the 3 cheeses exposed to different wood smokes (P < 0.05). Hickory smoked cheeses had the highest intensities of flavors associated with characteristic “smokiness” including smoke aroma, overall smoke flavor intensity, and meaty, smoky flavor. Cherry wood smoked cheeses were distinguished by the presence of a fruity flavor. Apple wood smoked cheeses were characterized by the presence of a waxy, green flavor. Ninety-nine aroma-active compounds were identified in smoked cheeses. Phenol, guaiacol, 4-methylguaiacol, and syringol were identified as the most important compounds contributing to characteristic “smokiness.” Benzyl alc. contributed to the fruity flavor in cherry wood smoked cheeses, and 2-methyl-2-butenal and 2-ethylfuran were responsible for the waxy, green flavor identified in apple wood smoked cheeses. These smoke flavor compounds, in addition to diacetyl and acetoin, were deemed important to the flavor of cheeses in this study. from this study identified volatile aroma-active compounds contributing to differences in sensory perception among Cheddar cheeses smoked with different wood sources.

Journal of Dairy Science published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Perez, Dolores published the artcileEffect of non-wine Saccharomyces yeasts and bottle aging on the release and generation of aromas in semi-synthetic Tempranillo wines, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is International Journal of Food Microbiology (2022), 109554, database is CAplus and MEDLINE.

Interest in the use of non-conventional yeasts in wine fermentation has been increased in the last years in the wine sector. The main objective of this manuscript was to explore the aromatic diversity produced by wild and non-wine strains of S. cerevisiae, S. eubayanus, S. kudriavzevii, and S. uvarum species in young and bottle-aged Tempranillo wines as well as evaluate their fermentation capacity and the yield on ethanol, glycerol, and organic acids, that can contribute to diminishing the effects of climate change on wines. S. uvarum strain U1 showed the highest ability to release or de novo produce monoterpenes, such as geraniol and citronellol, whose values were 1.5 and 3.5-fold higher than those of the wine S. cerevisiae strain. We found that compared to the normal values for red wines, β-phenylethyl acetate was highly synthesized by U1 and E1 strains, achieving 1 mg/L. Addnl., after aging, wines of S. eubayanus strains contained the highest levels of this acetate. Malic acid was highly degraded by S. kudriavzevii yeasts, resulting in the highest yields of lactic acid (>5-fold) and Et lactate (>2.8-fold) in their wines. In aged wines, we observed that the modulating effects of yeast strain were very high in β-ionone. S. uvarum strains U1 and BMV58 produced an important aging attribute, Et isobutyrate, which was highly enhanced during the aging. Also, the agave S. cerevisiae strain develops an essential aroma after aging, reaching the highest Et leucate contents. According to the results obtained, the use of wild non-wine strains of S. cerevisiae and strains of the cryotolerant species S. eubayanus, S. kudriavzevii, and S. uvarum in Tempranillo wine fermentation increase the aroma complexity. In addition, wines from S. kudriavzevii strains had twice addnl. glycerol, those from S. uvarum 4-fold more succinic acid, while wines from wild strains yielded 1% volume/volume less ethanol which may solve wine problems associated with climate change.

International Journal of Food Microbiology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Application of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhao, Lanxiao published the artcileRegioselective C-H Alkylation of Aromatic Ethers with Alkenes by a Half-Sandwich Calcium Catalyst, SDS of cas: 93-04-9, the publication is ACS Catalysis (2022), 12(13), 7877-7885, database is CAplus.

The catalytic ortho-regioselective C-H alkylation of a of alkoxy-substituted benzene derivatives with alkenes could be achieved by the use of a half-sandwich calcium alkyl complex [(CpAr₅)Ca{CH(SiMe₃)₂}(THF)] (CpAr₅ = C₅Ar₅, Ar = 3,5-i-Pr-C₆H₃) as the precatalyst to form 1-alkoxy-2-phenethylbenzene derivatives I [R = H, 4-Me, 4-SMe, etc.; R¹ = OMe, OEt, i-Pr, etc.]. The potential catalytic reaction intermediates, half-sandwich calcium anisyl complexes [(CpAr₅)Ca(o-MeO-m-Ph-C₆H₃) (THF)₂] and [(CpAr₅)Ca(o-MeO-2-Np) (THF)₂] (Np = naphthyl), were isolated and X-ray structurally characterized. DFT calculations were carried out to elucidate the different reaction profiles of sp² and sp³ C-H activations.

ACS Catalysis published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C19H14Cl2, SDS of cas: 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lee, Yong Ho published the artcilePalladium-catalysed carboformylation of alkynes using acid chlorides as a dual carbon monoxide and carbon source, Product Details of C11H10O, the publication is Nature Chemistry (2021), 13(2), 123-130, database is CAplus and MEDLINE.

Hydroformylation, a reaction that installs both a C-H bond and an aldehyde group across an unsaturated substrate, is one of the most important catalytic reactions in both industry and academia. Given the synthetic importance of creating new C-C bonds, the development of carboformylation reactions, wherein a new C-C bond is formed instead of a C-H bond, would bear enormous synthetic potential to rapidly increase mol. complexity in the synthesis of valuable aldehydes. However, the demanding complexity inherent in a four-component reaction, utilizing an exogenous CO source, has made the development of a direct carboformylation reaction a formidable challenge. Here, we describe a palladium-catalyzed strategy that uses readily available aroyl chlorides as a carbon electrophile and CO source, in tandem with a sterically congested hydrosilane, to perform a stereoselective carboformylation of alkynes [e.g., 2-methylbenzoyl chloride + i-Pr₃SiH + n-PrCCPr-n â†?(Z)-I (up to 83%)]. An extension of this protocol to four chemodivergent carbonylations further highlights the creative opportunity offered by this strategy in carbonylation chem.

Nature Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Product Details of C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Coniglio, Romina O. published the artcileEnzyme-assisted extraction of phenolic compounds and proteins from sugarcane bagasse using a low-cost cocktail from Auricularia fuscosuccinea, Related Products of ethers-buliding-blocks, the publication is International Journal of Food Science and Technology (2022), 57(2), 1114-1121, database is CAplus.

Sugarcane bagasse is the major byproduct of the sugarcane industry, and it can serve as a substrate for biotechnol. processes for obtaining value-added products. This study gave multiple adding values to sugarcane bagasse using it in two sep. bioprocesses. Sugarcane bagasse was used as a substrate for enzymic cocktail production from Auricularia fuscosuccinea LBM 244 and as a source of proteins and phenolic compounds A. fuscosuccinea LBM 244 enzyme cocktail-assisted extraction, com. enzyme assisted extraction and conventional extraction were compared. Enzymic-assisted extractions released 557-827% more protein content than those at 0 h. A. fuscosuccinea LBM 244 enzyme cocktail released 50% and 30% phenolic compounds more than conventional and com. enzyme extraction, resp. These phenolic compounds were represented mainly by ρ-coumaric and ferulic acids. On top of that, the cost of the enzymes in enzyme-assisted extraction was reduced fourfold using the A. fuscosuccinea LBM 244 enzyme cocktail.

International Journal of Food Science and Technology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Paquette, Leo A. published the artcileSynthesis of optically active triazolinediones and examination of their utility for inducing asymmetry in Diels-Alder cycloaddition reactions, Application In Synthesis of 2944-47-0, the publication is Journal of Organic Chemistry (1980), 45(25), 5105-13, database is CAplus.

Optically active triazolinedione derivatives of (-)-PhCHMeNH₂, (+)-dehydroabietylamine acetate, and (+)-camphor, I–III, resp., were prepared and their ability to discriminate between diastereomeric transition states in their Diels-Alder reactions with racemic and optically active p-mentha-2,4-diene and α-phellandrene was studied. In each case plotting the [α]_D of the adduct from the diene of known optical purity and that of the adduct from the racemic dienes vs. diastereomeric purity served to delineate the enantioselectivity and the absolute configuration of the adducts. The triazolinedione derivatives are also useful for nondestructive resolution of compounds

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wu, Shaofeng published the artcilePhosphorous Acid-Catalyzed Alkylation of Phenols with Alkenes, Safety of 2-Methoxynaphthalene, the publication is Journal of Organic Chemistry (2020), 85(22), 14307-14314, database is CAplus and MEDLINE.

A H₃PO₃-catalyzed alkylation of phenols with alkenes is achieved in a facile, efficient, and selective manner. The reaction shows a unique selectivity, i.e., excellent regioselectivity, thorough suppression of overalkylation, without alkylation of a simple Ph ring, and can selectively provide ortho-, meta-, or para-alkylated phenol derivatives in good to excellent yields. This feature along with mild reaction conditions, sensitive functional group tolerance, and scale-up synthesis and late modification of phenolic bioactive compounds make it an ideal and practical alternative for the modification of phenols.

Journal of Organic Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C25H16O, Safety of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem