Tag: M.W=150-200

Insyani, Rizki published the artcileImproved hydrodeoxygenation of lignin-derived oxygenates and biomass pyrolysis oil into hydrocarbon fuels using titania-supported nickel phosphide catalysts, COA of Formula: C9H10O4, the publication is Energy Conversion and Management (2022), 115822, database is CAplus.

Biomass pyrolysis oil is a potentially essential renewable energy source that can serve as an alternative to petroleum-based fuels and chems. In this study, biomass pyrolysis oil was converted into petroleum-like deoxygenated hydrocarbons via catalytic hydrodeoxygenation using a titania-supported nickel phosphide catalyst. The phosphor precursor was added to several transition metals, including nickel, cobalt, copper, and iron, supported on titania. The formation of isolated nickel phosphide particles, which were active for complete hydrodeoxygenation, was confirmed by the characterization of prepared catalysts. As a model reactant of biomass pyrolysis oil, a mixture of alkyl-methoxyphenol compounds was hydrodeoxygenated to produce completely deoxygenated compounds, generating an 87% yield of cycloalkanes at 300 °C and 4 MPa H2 for a reaction time of 2 h. The hydrodeoxygenation of biomass pyrolysis oil also generated a 37.4% yield of hydrocarbon fuels. The high hydrodeoxygenation activity can be attributed to the synergy between the hydrogenating metals and the acid sites, which can be improved by electron transfer from a slightly cationic nickel to a slightly anionic phosphor. Furthermore, the addition of phosphor improved the formation of highly dispersed nickel particles, increasing the quantity of hydrogen-adsorbing surface metals. The observations in this study indicate that the efficient conversion of lignocellulose-derivatives into chems. and fuels can be achieved using modified non-precious transition metal catalysts.

Energy Conversion and Management published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, COA of Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chang, Hson Mou published the artcileCompounds from Danshen. Part 4. Structure-activity relationship of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen), Related Products of ethers-buliding-blocks, the publication is Journal of Medicinal Chemistry (1991), 34(5), 1675-92, database is CAplus and MEDLINE.

Twenty-one o-quinonoid-type compounds, e.g. I–VI and one coumarin-type compound related to miltirone (VII) were synthesized for identification of the key structural elements involved in the reaction of VII with the central benzodiazepine receptor. Based on their inhibition of [³H]flunitrazepam binding to bovine cerebral cortex membranes, it was apparent that ring A of VII is essential for affinity. Although increasing the size of ring A from 6-membered to 7- and 8-membered is well-tolerated, the introduction of polar hydroxyl groups greatly reduces binding affinity. The presence of 1,1-di-Me groups on ring A is, however, not essential, but the iso-Pr group on ring C appears to be critical for binding as its removal decreases affinity by more than 30-fold. Its replacement with an Me group causes only a minimal reduction in affinity. Linking ring A and B with an -CH₂CH₂– bridge results in analog VIII which is 6 times more potent than VII at the central benzodiazepine receptor (IC₅₀ = 0.05 μM).

Journal of Medicinal Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Spadafora, Natasha D. published the artcileA complex interaction between pre-harvest and post-harvest factors determines fresh-cut melon quality and aroma, COA of Formula: C10H14O, the publication is Scientific Reports (2019), 9(1), 1-15, database is CAplus and MEDLINE.

Melons are prized for their characteristic aroma, however, pre-harvest growth, stage of ripening at harvest, post-harvest processing and storage conditions lead to quality changes in fresh-cut fruit. We considered changes in metabolites and gene expression over 14 days storage to assess underlying mechanisms and identify potential quality markers. Overall, 99 volatile organic compounds (VOCs) were detected and VOC profiles discriminated between two melon seasons, cut-size, storage temperatures and storage time, although season affected their discriminatory power. Abundance of two VOCs fell rapidly and was not associated with cut size, indicating their use as markers for early changes post-processing. Non-acetate to acetate ester ratio differed between the seasons and correlated with changes in alc. acyl-transferase (CmAAT1) gene expression. Furthermore, CmAAT1 expression clustered with two ester VOCs that may be potential new products of this enzyme. Season also strongly affected post-harvest sugar content, most likely attributable to meteorol. differences during growth. Storage temperature and cut size affected expression of transcription factors ERF71, ERF106, and TINY, whose expression generally rose during storage, probably related to increased stress. Thus, although time × temperature of storage are key factors, pre-harvest conditions and fruit processing impact significantly gene expression and aroma loss post-harvest.

Scientific Reports published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C9H9NO, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Casimiro, Filipa M. published the artcileHardwood and softwood lignins from sulfite liquors: Structural characterization and valorization through depolymerization, COA of Formula: C9H10O4, the publication is International Journal of Biological Macromolecules (2022), 272-279, database is CAplus and MEDLINE.

This work aims to evaluate the structural characteristics and study the oxidative depolymerization of lignins obtained from hardwood and softwood sulfite liquors. Lignins were obtained after ultrafiltration and freeze-drying of the sulfite liquors and characterized based on inorganic content, nitrobenzene oxidation, ¹³C NMR, and mol. weight determination The structural characteristics achieved allow evaluating the potential of each lignin through oxidative depolymerization to produce added-value phenolic monomers. Hardwood and softwood lignins were submitted to alk. oxidation with oxygen and the reaction conditions optimized to obtain a final oxidation mixture with the maximum yield of phenolic monomers. Through oxidation with O₂, hardwood lignin generates mostly syringaldehyde while lignin from softwood biomass mainly produces vanillin; moreover, a lower reaction time and the interruption of O₂ admission avoid the degradation of the oxidation products in the final mixture for both lignins, more evidenced to hardwood lignin due to its higher reactivity. From the results, it is possible to conclude that a phenolic aldehyde-rich oxidation mixture could be obtained, confirming the viability of lignin as raw material to produce added-value products as vanillin and syringaldehyde.

International Journal of Biological Macromolecules published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, COA of Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Loubinoux, B. published the artcileSelective demethylation of aryl methyl ethers, Formula: C10H14O, the publication is Synthesis (1980), 638-40, database is CAplus.

Title ethers RC₆H₄OMe (R = 3-Me, 4-Me, 2-Me₂CH, 2-MeO, 3-MeO, 4-MeO) were treated with PhMeNNa in the presence of (Me₂N)₃PO to give 80-95% RC₆H₄OH. Monodealkylation of Me ethers of polyhydric phenols, e. g., 1,3,5-trimethoxybenzene and the dimethoxybenzene isomers, was easily achieved. Both Me and benzyl ethers were cleaved but methyl ethers were cleaved more easily.

Synthesis published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhao, Jing published the artcileSynthesis of Benzoxaboroles by ortho-Oxalkylation of Arylboronic Acids with Aldehydes/Ketones in the Presence of Bronsted Acids, Recommanded Product: (3-Methoxy-5-methylphenyl)boronic acid, the publication is Organic Letters (2021), 23(6), 1986-1990, database is CAplus and MEDLINE.

Herein the authors describe a simple and efficient synthesis of benzoxaboroles from arylboronic acids and aldehydes or ketones in the presence of a Bronsted acid. This method greatly simplifies the starting materials and reduces the number of reaction steps. The reaction can also be accomplished with acetals and ketals. The reaction has a wide substrate scope and high practicability.

Organic Letters published new progress about 725251-81-0. 725251-81-0 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Methoxy-5-methylphenyl)boronic acid, and the molecular formula is C8H15ClN2, Recommanded Product: (3-Methoxy-5-methylphenyl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Webster-Gardiner, Michael S. published the artcileCatalytic Synthesis of “Super” Linear Alkenyl Arenes Using an Easily Prepared Rh(I) Catalyst, Synthetic Route of 2944-47-0, the publication is Journal of the American Chemical Society (2017), 139(15), 5474-5480, database is CAplus and MEDLINE.

Linear alkyl benzenes (LAB) are global chems. that are produced by acid-catalyzed reactions that involve the formation of carbocationic intermediates. One outcome of the acid-based catalysis is that 1-phenylalkanes cannot be produced. Herein, it is reported that [Rh(μ-OAc)(η²-C₂H₄)₂]₂ catalyzes production of 1-Ph substituted alkene products via oxidative arene vinylation. Since C=C bonds can be used for many chem. transformations, the formation of unsaturated products provides a potential advantage over current processes that produce saturated alkyl arenes. Conditions that provide up to a 10:1 linear:branched ratio have been achieved, and catalytic turnovers >1470 have been demonstrated. In addition, electron-deficient and electron-rich substituted benzenes are successfully alkylated. The Rh catalysis provides ortho:meta:para selectivity that is opposite to traditional acid-based catalysis.

Journal of the American Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C5H5NO3S, Synthetic Route of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Chengxi published the artcileEfficient Synthesis of Sterically Hindered Arenes Bearing Acyclic Secondary Alkyl Groups by Suzuki-Miyaura Cross-Couplings, Application In Synthesis of 2944-47-0, the publication is Angewandte Chemie, International Edition (2015), 54(12), 3792-3796, database is CAplus and MEDLINE.

Bulky P,P:O ligands I (R = H, OMe, NMe₂) were designed and synthesized to inhibit isomerization and reduction side reactions during the cross coupling between sterically hindered aryl halides and alkylboronic acids. Suzuki-Miyaura cross-couplings between di-ortho-substituted aryl bromides and acyclic secondary alkylboronic acids using one of these ligands were achieved with high yields. The method also enabled the preparation of ortho-alkoxy/di-ortho-substituted arenes bearing iso-Pr groups in excellent yields. The utility of the synthetic method was demonstrated in a late-stage modification of estrone and in the application to a new synthetic route towards gossypol.

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Jia-Qin published the artcileBromination of phenyl ether and other aromatics with bromoisobutyrate and dimethyl sulfoxide, Recommanded Product: 2-Methoxynaphthalene, the publication is Tetrahedron Letters (2021), 153375, database is CAplus.

Bromoisobutyrate was used for the first time as a general brominating source for the direct bromination of a diverse of simple Ph ethers. Aromatic ethers bearing various substituents was compatible in this reaction system delivered brominated arenes ArOMe [Ar = 4-Br-2,3-diMeC₆H₂, 4-NHAc-3-Br-C₆H₃, 1-Br-2-naphthyl, etc.] in moderate to good yields. The reaction system was expanded to bromination of phenols and unactivated arene. This process was regarded as an alternative for the well-established bromination systems for bromoarene synthesis.

Tetrahedron Letters published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Ying-Qi published the artcileAsymmetric dearomatization catalysed by chiral Bronsted acids via activation of ynamides, Category: ethers-buliding-blocks, the publication is Nature Chemistry (2021), 13(11), 1093-1100, database is CAplus and MEDLINE.

The chiral Bronsted acids enable the catalytic asym. dearomatization reactions of naphthols- phenols- RCCN(R¹)R² (R = 2-(4-hydroxynaphthalen-1-yl)benzen-1-yl, 2-(4-hydroxy-1,4,5,6,7,8-hexahydronaphthalen-1-yl)benzen-1-yl, 2-(2-hydroxyphenyl)benzen-1-yl, etc.; R¹ = Ms, Ts, Bs, etc.; R² = Ph, naphthalen-2-yl, n-Bu, etc.) and pyrrole-ynamides R³(CH₂)₂NCC(R¹)R² (R³ = 2,5-dimethyl-1H-pyrrol-1-yl, 2-methyl-5-(thiophen-3-yl)-1H-pyrrol-1-yl, 2-methyl-5-phenyl-1H-pyrrol-1-yl, etc.) by the direct activation of alkynes. This method leads to the practical and atom-economic construction of various valuable spirocyclic enones I (R⁴ = H, 6-F, benzene-1,2-bis(yl), 5-Cl, etc.) and II, 2H-pyrroles III (R⁵ = Me, Ph, thiophen-2-yl, etc.; R⁶ = Me, Et) that bear a chiral quaternary carbon stereocenter in generally good-to-excellent yields with excellent chemo-, regio- and enantioselectivities. The activation mode of chiral Bronsted acid catalysis revealed in this study is expected to be of broad utility in catalytic asym. reactions that involve ynamides and the related heteroatom-substituted alkynes.

Nature Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C10H14O, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem