Tag: M.W=150-200

Xiong, Ying published the artcileEnantioselective Total Synthesis of (-)-Hamigeran F and Its Rearrangement Product, Application In Synthesis of 725251-81-0, the publication is Organic Letters (2022), 24(28), 5161-5165, database is CAplus and MEDLINE.

Herein, we report the first enantioselective total synthesis of the highly complex hamigeran diterpenoid (-)-hamigeran F and its rearrangement product. The synthetic strategy features key steps of asym. hydrogenation, Horner-Wadsworth-Emmons olefination, and intramol. Friedel-Crafts acylation to construct the [6,6,5]-tricyclic skeleton bearing three consecutive stereocenters, a sequence of steps involving Rosenmund reduction, Wittig reaction, dihydroxylation to assemble the α-acetoxy ketone group, and an intramol. aldol reaction to build the tetracyclic core structure.

Organic Letters published new progress about 725251-81-0. 725251-81-0 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Methoxy-5-methylphenyl)boronic acid, and the molecular formula is C18H23N3O4S, Application In Synthesis of 725251-81-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yao, Juanjuan published the artcileNew insight into the regulation mechanism of visible light in naproxen degradation via activation of peroxymonosulfate by MOF derived BiFeO₃, Application of 2-Methoxynaphthalene, the publication is Journal of Hazardous Materials (2022), 128513, database is CAplus and MEDLINE.

BiFeO₃ (BFO) nanocage prepared by metal-organic-framework derivatization (MOF-d) was adopted as activator to first investigate the effect mechanism of visible-light on naproxen-degradation via peroxymonosulfate (PMS) activation. MOF-d BFO expressed more excellent PMS activation ability than hydrothermal-synthetic BFO, due to highly ordered mesopores. A 3.0 times higher pseudo-first-order degradation rate constant was achieved after visible-light introduced. The quenching experiments indicated that the contribution of ROS in naproxen degradation followed the order of SO•^–₄>¹O₂ ≈ •OH in MOF-d BFO/PMS/dark system, while changed into h⁺>¹O₂ > >O•-app2SO•^–₄> •OH after visible-light introduced. EPR tests first revealed that visible-light promoted ¹O₂ yield (non-radical pathway) but suppressed •OH and SO•^–₄ generation (free-radical pathways). N2-purging experiments further proved that ¹O₂ primarily originates from the reaction between h⁺ and PMS, equivalently to that between O₂ and e^–-h⁺ in MOF-d BFO/PMS/vis system. Under visible-light, PMS activation via Fe (III) might be hindered by e- filling on Fe 3d orbital and anion PMS preferred to approach h⁺ rather than e^–, resulting in the decrease of •OH and SO•^–₄ yields. Moreover, PMS faces competition from adsorbed-O₂ and oxygen-vacancies for e^– capture. The degradation-pathways for naproxen in dark and under visible light were both proposed in MOF-d BFO/PMS system.

Journal of Hazardous Materials published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C22H38O2, Application of 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, Recommanded Product: 2-Methoxynaphthalene, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chang, Hson Mou published the artcileStructure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen), HPLC of Formula: 2944-47-0, the publication is Journal of Organic Chemistry (1990), 55(11), 3537-43, database is CAplus.

Eleven new compounds were isolated from the dried root of Salvia miltiorrhiza Bunge “Danshen”, and their structures were elucidated by spectrometric methods. The total syntheses of 2 new compounds namely, 1,2-didehydromiltirone (I) and 4-methylenemiltirone (II) are also reported.

Journal of Organic Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, HPLC of Formula: 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Lui, Yuen Wai published the artcileMethylation with Dimethyl Carbonate/Dimethyl Sulfide Mixtures: An Integrated Process without Addition of Acid/Base and Formation of Residual Salts, COA of Formula: C11H10O, the publication is ChemSusChem (2022), 15(3), e202102538, database is CAplus and MEDLINE.

Di-Me sulfide, a major byproduct of the Kraft pulping process, was used as an inexpensive and sustainable catalyst/co-reagent (Me donor) for various methylations with di-Me carbonate (as both reagent and solvent), which afforded excellent yields of O-methylated phenols and benzoic acids, and mono-C-methylated arylacetonitriles. Furthermore, these products could be isolated using a remarkably straightforward workup and purification procedure, realized by di-Me sulfide’s neutral and distillable nature and the absence of residual salts. The likely mechanisms of these methylations were elucidated using exptl. and theor. methods, which revealed that the key step involves the generation of a highly reactive trimethylsulfonium methylcarbonate intermediate. The phenol methylation process represents a rare example of a Williamson-type reaction that occurs without the addition of a Bronsted base.

ChemSusChem published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, COA of Formula: C11H10O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Qingyu published the artcileHypervalent Chalcogenonium…π Bonding Catalysis, Synthetic Route of 93-04-9, the publication is Angewandte Chemie, International Edition, database is CAplus and MEDLINE.

A proof-of-concept study of hypervalent chalcogenonium…π bonding catalysis was performed. A new catalytic strategy using 1,2-oxaselenolium salts as chalcogen bond donors and alkenes as chalcogen bond acceptors is described. The feasibility of this concept is demonstrated by the use of trisubstituted selenonium salts in the metal-free catalytic hydrofunctionalization and polymerization of alkenes via unconventional seleniranium ion-like intermediates. The results indicate that counter anions have a significant effect on the catalysis based on hypervalent chalcogenonium…π bonding interactions.

Angewandte Chemie, International Edition published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C9H9BN2O2, Synthetic Route of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Tan, Ming published the artcileRoasting treatments affect physicochemical, aroma and nutritional quality of strong fragrant rapeseed oil, Related Products of ethers-buliding-blocks, the publication is Journal of Food Composition and Analysis (2022), 104648, database is CAplus.

The strong fragrant rapeseed oil (SFRO) attracts the growing interest in China due to its fragrant flavor, attractive color, and phys. and oxidative stability. It is usually produced with simple processes including rapeseed roasting, mech. pressing, and degumming with hot water (80-90°C). To produce SFROs with high quality and nutritional contents, the seed roasting parameters including temperature up to 220°C and time ranging from 10 min to 30 min were investigated. Results showed that 20-min roasting at temperature 160°C resulted in the highest oil extraction yield of 33.20% with the lowest water content of 0.121%. The produced SFRO had the roasted, nutty and soft tastes with the maximum overall score, the highest total tocopherol and sterol contents of 789.73 mg/kg and 4582.80 mg/kg, resp., and high CoQ10 content of 65.57 mg/kg. Over-roasting at roasting temperature of over 180°C and time of over 30 min led to the high Lovibond red readings, off-flavors, and increased concentrations of high saturated fatty acids and Benzo[a]pyrene (BaP). Our findings would provide a reference to produce SFROs with the highest extraction yield and nutrient contents, acceptable physicochem. properties, optimal profile of the fatty acids and the key aroma compounds, and relatively-low BaP concentration

Journal of Food Composition and Analysis published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C15H14BNO4S, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zou, Zidan published the artcileCore shell hetero-structured SiO₂@Ni/SiO₂ catalyst for efficient aqueous-phase hydrogenation of bio-derived unsaturated compounds, SDS of cas: 134-96-3, the publication is Fuel (2022), 123694, database is CAplus.

Silica is one of the most referenced materials for the preparation of heterogeneous metal catalysts. However, silica spheres with smooth surfaces have difficulty encapsulating active metals due to their small surface area and the presence of only a handful of silicon hydroxyl groups on the surface. In this work, the silica sphere has been first consciously transformed into a hierarchical SiO₂@silicate structure, and then the core-shell hetero-structured SiO₂@Ni/SiO₂ catalyst can be tactfully obtained by reducing treatment. The core-shell catalyst is composed of a rigid core (SiO2) and a rough shell (Ni NPs highly disperse on nanosheet SiO₂), which are carefully verified by X-ray diffraction (XRD), transmission electron microscope (TEM), field scanning electron microscope (FESEM), H₂-TPR/TPD and XPS. The derived SiO₂@Ni/SiO₂ catalyst can selectively hydrogenate vanillin in the aqueous phase at near-room temperature (40 °C) and low hydrogen pressure (2 MPa H₂), and the conversion of vanillin can be up to 99%. The preparation method of the SiO₂@Ni/SiO₂ catalyst is simple and can be amplified to a large scale at a low price, thus can be adopted to convert bio-derived unsaturated compounds in an economical and eco-friendly way.

Fuel published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C10H16BNO2, SDS of cas: 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Secinti, Hatice published the artcileTotal Syntheses of Multicaulins via Oxidative Photocyclization of Stilbenes, Application In Synthesis of 2944-47-0, the publication is Journal of Natural Products (2014), 77(9), 2134-2137, database is CAplus and MEDLINE.

The Wittig reaction of 3-isopropyl-4-methoxybenzaldehyde and 2,3-dimethylbenzylphosphonium bromide afforded the corresponding stilbene mixture I. Oxidative photocyclization of stilbene I with iodine facilitated the first total synthesis of 7-isopropyl-6-methoxy-1,2-dimethylphenanthrene, multicaulin (II). The O-demethylation of II with BBr₃ afforded the 7-isopropyl-1,2-dimethylphenanthren-6-ol, O-demethylmulticaulin (III).

Journal of Natural Products published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C16H10O5, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Yi, Wen-Bin published the artcileFriedel-Crafts alkylation in fluorous biphasic system catalyzed by rare earth(III) perfluorooctanesulfonate, Recommanded Product: 2-Isopropylanisole, the publication is Yingyong Huaxue (2006), 23(2), 212-214, database is CAplus.

Rare earth (III) perfluorooctanesulfonate salts (catalysts) were prepared and used in Friedel-Crafts alkylation in fluorous biphasic systems. Perfluorohexane, perfluoromethylcyclohexane, perfluorotoluene, perfluorooctane, perfluorooctyl bromide and perfluorodecalin can be used as the fluorous solvent for this kind of reaction. The catalytic activities of other rare earth metal salts with different ligands were tested. The results show that Yb(OSO₂C₈F₁₇)₃ [1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonic acid ytterbium(3+) salt], ,and C₁₀F₁₈ were the best catalyst and fluorous solvent resp. The yield of alkylation of anisole with benzyl alc. was 96% in the presence of Yb(OSO₂C₈F₁₇)₃ and C₁₀F₁₈. By simple phase-separation the fluorous phase containing only catalyst could be re-utilized up to five times with a slight decrease in activity.

Yingyong Huaxue published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C18H26ClN3O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem