Tag: M.W=150-200

Yi, Wen-Bin published the artcileRare earth(III) perfluorooctanesulfonates catalyzed Friedel-Crafts alkylation in fluorous biphase system, Application of 2-Isopropylanisole, the publication is Journal of Fluorine Chemistry (2005), 126(5), 831-833, database is CAplus.

The catalyst of rare earth(III) perfluorooctanesulfonates (RE(OSO₂C₈F₁₇)₃, RE = Sc, Y, La-Lu) were prepared from either rare earth(III) chlorides or oxides and perfluorooctanesulfonic acid. The perflates thus obtained act as novel catalysts for Friedel-Crafts alkylation in fluorous biphasic system. Perfluorohexane (C₆F₁₄), perfluoromethylcyclohexane (C₇F₁₄), perfluorotoluene (C₇F₈), perfluorooctane (C₈F₁₈), perfluorooctyl bromide (C₈F₁₇Br), and perfluorodecalin (C₁₀F₁₈, cis- and trans-mixture) can be used as fluorous solvents for this reaction. By simple separation of the fluorous phase containing only catalyst, alkylation can be repeated many times.

Journal of Fluorine Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C3H8N2S, Application of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gui, Jingjing published the artcileFacile and practical hydrodehalogenations of organic halides enabled by calcium hydride and palladium chloride, Quality Control of 93-04-9, the publication is Organic Chemistry Frontiers (2021), 8(17), 4685-4692, database is CAplus.

Herein, a convenient hydrodehalogenation method was described by employing less-explored calcium hydride as the reductant. A wide range of organic halides such as aromatic bromides RBr (R = 4-(dimethylamino)phenyl, 4-aminonaphthalen-1-yl, quinolin-5-yl, etc.), aromatic chlorides R¹Cl (R¹ = naphthalen-1-yl, 3-carboxy-5-methoxyphenyl, 2-[2-(cyclohexa-1,5-dien-1-yl)ethenyl]phenyl, etc.), aromatic triflates R²Otf (R² = 2-methylquinolin-8-yl, 2-nitrophenyl, 2-acetylnaphthalen-1-yl, etc.), 1-(2-(4-bromo/chlorobutoxy)phenyl)ethan-1-one were efficiently and selectively reduced to obtain the corresponding hydrocarbons e.g., Phenyl(pyrrolidin-1-yl)methanone. More importantly, monodehalogenation of trihalomethyl compounds R³CXY₂ (R³ = benzenesulfonyl, 3-oxo-1-phenyl-3-(thiophen-3-yl)propyl, N-(naphthalen-1-yl)carbamoyl, etc.; X = Br, Cl; Y = Br, Cl, F) in THF could provide various useful dihalomethyl products R³CHY₂.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Quality Control of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sun, Guodong published the artcileOrganic matter biomarker and ¹³C NMR characteristics of soil and sediment standard reference materials from China, Formula: C9H10O4, the publication is Science of the Total Environment (2022), 155661, database is CAplus and MEDLINE.

Soil and sediment organic matter (OM) in terrestrial environments represent two critical organic carbon pools on Earth and are likely subject to distinct degrees of oxidation and modification. However, few studies have identified critical mol.-level characteristics that differentiate soil and sediment OM from various climate zones. Using biomarkers and solid-state ¹³C NMR (NMR) spectroscopy analyses, we studied the OM characteristics of 11 soil and 7 sediment standard reference materials (SRMs) originating from various geog. locations in China. Results showed significantly higher concentrations of lignin phenols in sediment OM than in soil OM, which may result from protection by higher contents of CaO and less microbial degradation in sediments. Nevertheless, the relative abundances of solvent-extractable lipids (alkanes, alkanols, and alkanoic acids) and ester-bound cutin and suberin biomarkers did not differ significantly between soil and sediment SRMs. The concentrations of lignin biomarkers decreased with increasing weathering degree of the soil, while cutin biomarkers increased with mean annual temperature and precipitation This phenomenon was not observed in sediment SRMs. This study reveals the distinct OM characteristics between Chinese soil and sediment SRMs and provides fundamental data for future studies to link OM characteristics and functions.

Science of the Total Environment published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C10H20O2, Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ruan, Jing-Ya published the artcileStructural characterization of phenolic constituents from the rhizome of Imperata cylindrica var. major and their anti-inflammatory activity, HPLC of Formula: 134-96-3, the publication is Phytochemistry (Elsevier) (2022), 113076, database is CAplus and MEDLINE.

As one of raw materials, the rhizome of Imperata cylindrica var. major (Nees) C. E. Hubb. is used in kinds of preparations curing inflammation related diseases, while its effective substances are not yet clear. In this paper, its chem. constituents and their anti-inflammatory activities were investigated. As results, ten compounds, named as imperphenoside A (1), imperphenols B (2) and C (3), imperphenosides D-F (4-6), and imperlignanosides A-D (7-10), along with previously reported thirty-seven known ones (11-47) were obtained from it. Their structures were ascertained basing on the extensive spectroscopic methods and electronic CD data anal. Meanwhile, compounds 4, 11, 12, 24, 27, 31, 32, 37, 43, 45, and 47 exhibited nitric oxide inhibitory effects in concentration dependent at 3, 10, and 30 μM on lipopolysaccharides induced RAW 264.7 cells. Moreover, the western blot anal. indicated that compounds 4, 11, 43, and 47 could restrain the phosphorylation of nuclear factor kappa-B kinase to down-regulate the protein expression of inflammatory cytokines such as inducible nitric oxide synthase, interleukin-6 and tumor necrosis factor-α. In conclusion, they might play the anti-inflammatory effects through regulating NF-κB signaling pathway.

Phytochemistry (Elsevier) published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, HPLC of Formula: 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Burnell, Robert H. published the artcileApproach to the synthesis of candelabrone and synthesis of 3,7-diketo-12-hydroxyabieta-8,11,13-triene., Product Details of C10H14O, the publication is Canadian Journal of Chemistry (1992), 70(5), 1446-54, database is CAplus.

An approach to the synthesis of aromatic diterpenes was tested for its generality. Phenylacetonitriles with increasing substitution on the aromatic ring were prepared and alkylated with geranyl bromide and the resulting dienes, e.g. I, subjected to cationic cyclization. The less-substituted examples afforded tricyclic products of the required stereochem., e.g. II, while the more highly substituted compounds cyclized with reduced yields or not at all. One of the intermediates III was used to synthesize nimosone IV, a natural diterpene isolated originally from Chamaecyparis formosensis and recently from Azadirachta indica.

Canadian Journal of Chemistry published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Burnell, Robert H. published the artcileSynthesis of aromatic diterpenes. Synthesis of 12-hydroxyabieta-8,11,13-triene-3,7-dione, Recommanded Product: 2-Isopropylanisole, the publication is Synthetic Communications (1991), 21(1), 127-32, database is CAplus.

Model studies involving cationic cyclization. of suitable dienes have provided a synthesis of the title compound (I). Preparation of the dienes from available aromatic starting materials and the modification of the cyclized products are described. Thus, nitrile II in MeNO₂ was treated with PhSMe and BF₃ to give III, which was converted to I in 4 steps.

Synthetic Communications published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Jimenez-Sanchez, Maria published the artcileThe impact of ultrasound, micro-oxygenation and oak wood type on the phenolic and volatile composition of a Tempranillo red wine, Computed Properties of 134-96-3, the publication is LWT–Food Science and Technology (2022), 113618, database is CAplus.

The accelerated ageing of a Tempranillo red wine has been studied at pilot scale through the combined application of ultrasound, micro-oxygenation and different oak wood type chips (American, French and Spanish). The phenolic and volatile content of the aged samples and their sensory profiles have been determined The wine samples that had been aged using micro-oxygenation, French or American oak chips, and ultrasound revealed to be similar in terms of polyphenols to those wines that had been aged without implementing this last accelerating technique. Ageing time, with a high extraction kinetics, was the most significant variable with regard to their polyphenol content. In terms of volatiles, Spanish and French oak wood wine samples showed a similar behavior closely associated to ageing time, while American oak wood achieved a rather low enrichment in volatile constituents, resulting in a poor sensory profile of the final wines, which was particularly poor in the case of ultrasound aged wines.

LWT–Food Science and Technology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Computed Properties of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Han, Chong published the artcileNegishi Coupling of Secondary Alkylzinc Halides with Aryl Bromides and Chlorides, Recommanded Product: 2-Isopropylanisole, the publication is Journal of the American Chemical Society (2009), 131(22), 7532-7533, database is CAplus and MEDLINE.

An efficient palladium-catalyzed process has been developed for Negishi coupling of secondary alkylzinc halides with a wide range of aryl bromides and activated aryl chlorides. A palladium catalyst composed of a new biaryldialkylphosphine ligand, CPhos, effectively promotes the rate of the reductive elimination step relative to the rate of the undesired β-hydride elimination. The broad substrate scope and excellent ratio of the desired secondary to the undesired primary coupling product make this method a powerful and reliable tool for C(sp³)-C(sp²) bond formation.

Journal of the American Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Recommanded Product: 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Royer, Rene published the artcileReactioons induced by pyridine hydrochloride. IX. Possible uses of pyridine hydrochloride analogs for the dealkylation of phenolic ethers, COA of Formula: C10H14O, the publication is Bulletin de la Societe Chimique de France (1971), 4362-7, database is CAplus.

Pyridine hydrobromide (I) gave higher dealkylation yields of 2-alkoxynaphthalenes than pyridine hydrochloride (II), although temperatures >250° had to be used instead of ∼220°. The 2-naphthol yield from 2-isobutoxynaphthalene was 91% with I, compared with 11% for II. I also gave higher dealkylation yields of substituted anisoles, except those with large substituents next to the methoxy group. Thus for 2,6-diisopropylanisole demethylation was accompanied by isopropyl cleavage. PhNH2.HCl was less efficient than II as a dealkylating agent. 2,4-Lutidine hydrochloride was too sublimable to be used, but 3- and 4-picoline hydrochlorides were effective replacements for II. 2-Picoline retained too much H2O to be useful. Et2NH.HCl, BuNH2.HCl, and iso-BuNH2.HCl were less efficient dealkylating agents than II.

Bulletin de la Societe Chimique de France published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Royer, Rene published the artcileReactions induced by pyridine hydrochloride. VI. Comparison of the sensitivities to dealkylation by pyridine hydrochloride of alkyl ethers of phenols according to their structures, Safety of 2-Isopropylanisole, the publication is Bulletin de la Societe Chimique de France (1970), 3647-50, database is CAplus.

Increasing the dealkylation temperature of β-naphthyl alkyl ethers or the demethylation temperature of mono- or disubstituted anisoles with pyridinium hydrochloride decreases the effect of steric factors. The demethylation rates and product yields at 155° decreased in the order: PhOMe > o-MeC6H4OMe > o-EtC6H4OMe > o-BuC6H4-OMe; at reflux temperature the demethylation rates of these compounds were similar. The steric factors (proximity, branching of the substituents) are counterbalanced by the inductive effects and to some extent by the symmetry of the ethers. The dealkylation conditions must be optimized for each ether sep.

Bulletin de la Societe Chimique de France published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Safety of 2-Isopropylanisole.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem