Tag: M.W=150-200

Yu, Congjun published the artcileRegioselective Oxidative Arylation of Fluorophenols, Recommanded Product: (2-Chloroethoxy)benzene, the main research area is regioselective oxidative arylation fluorophenol; quinone regioselective preparation; arylated quinone; cross dehydrogenative coupling; fluorophenols; hypervalent iodine; regioselective arylation.

A metal free and highly regioselective oxidative arylation reaction of fluorophenols is described. The relative position of the fluoride leaving group (i.e., ortho or para) controls the 1,2 or 1,4 nature of the arylated quinone product, lending versatility and generality to this oxidative, defluorinative, arylation concept.

Angewandte Chemie, International Edition published new progress about Fluorophenols Role: RCT (Reactant), RACT (Reactant or Reagent). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Recommanded Product: (2-Chloroethoxy)benzene.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chu, Guobiao published the artcileA new and more efficient synthesis of methylene acetals, Recommanded Product: (2-Chloroethoxy)benzene, the main research area is methylene acetal preparation alc dichloromethoxytriazine.

A new and efficient synthesis of benzyl chlorides and methylene acetals by use of 2,4-dichloro-6-methoxy[1,3,5]triazine (MeOTCT) and DMSO has been developed. Chlorides are the major products for benzyl alcs., while methylene acetals are the major products for secondary alcs. This procedure provides the highest yields so far for methylene acetals of steroids. A plausible mechanism is proposed on the basis of the experiments

Synthesis published new progress about Acetals Role: SPN (Synthetic Preparation), PREP (Preparation). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Recommanded Product: (2-Chloroethoxy)benzene.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wang, Zijing published the artcileSynthesis of NHC Pincer Hydrido Nickel Complexes and Their Catalytic Applications in Hydrodehalogenation, Application In Synthesis of 622-86-6, the main research area is nickel bromide pincer complex hydrogenation hydride reagent; hydrido nickel pincer complex preparation catalyst alkyl halide hydrodehalogenation; crystal structure aminocarbeneamine nickel hydride pincer complex; mol structure aminocarbeneamine nickel hydride pincer complex.

The C(carbene)N(amino)N(amine)-pincer Ni(II) bromides (1a – 1c) were hydrogenated to the corresponding Ni(II) hydrides (2a – 2c) by (EtO)3SiH/NaOtBu or NaBH4. These Ni(II) hydrides (2a -2c) were characterized by NMR and IR spectroscopy as well as x-ray diffraction. The catalytic performance of complex 2b for hydrodehalogenation reactions was explored. In a combination of 3 mol% catalyst loading, (EtO)3SiH/NaOtBu/toluene/80° and different reaction time, organic halides were successfully reduced to the related alkanes. A catalytic radical mechanism is proposed and partly verified by experiments

Organometallics published new progress about Alkanes Role: SPN (Synthetic Preparation), PREP (Preparation). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Application In Synthesis of 622-86-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lamb, Jessica R. published the artcileCarbonylative, Catalytic Deoxygenation of 2,3-Disubstituted Epoxides with Inversion of Stereochemistry: An Alternative Alkene Isomerization Method, Related Products of ethers-buliding-blocks, the main research area is carbonylative deoxygenation epoxide inversion stereochem catalyst; alkene stereoselective preparation.

Reactions facilitating inversion of alkene stereochem. are rare, sought-after transformations in the field of modern organic synthesis. Although a number of isomerization reactions exist, most methods require specific, highly activated substrates to achieve appreciable conversion without side product formation. Motivated by stereoinvertive epoxide carbonylation reactions, we developed a two-step epoxidation/deoxygenation process that results in overall inversion of alkene stereochem. Unlike most deoxygenation systems, carbon monoxide was used as the terminal reductant, preventing difficult postreaction separations, given the gaseous nature of the resulting carbon dioxide byproduct. Various alkyl-substituted cis- and trans-epoxides can be reduced to trans- and cis-alkenes, resp., in >99:1 stereospecificity and up to 95% yield, providing an alternative to traditional, direct isomerization approaches.

Journal of the American Chemical Society published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Related Products of ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Uyanik, Muhammet published the artcileHypoiodite-catalysed oxidative homocoupling of arenols and tandem oxidation/cross-coupling of hydroquinones with arenes, SDS of cas: 121-00-6, the main research area is biarenol biquinone preparation; arenol oxidative homocoupling hypoiodite catalyst; aryl quinone preparation; hydroquinone arene tandem oxidation coupling hypoiodite catalyst.

The hypoiodite-catalyzed oxidative C-C homocoupling of arenols to biarenols or biquinones using aqueous hydrogen peroxide as an oxidant was reported. In addition, by combining hypoiodite catalysis and lipophilic Lewis acid-assisted Bronsted acid catalysis under aqueous conditions, a tandem oxidation/cross-coupling reaction of hydroquinones with electron-rich arenes was achieved. These results highlighted the substantial scope of hypoiodite/acid co-catalysis for use in oxidative coupling reactions.

Chemical Communications (Cambridge, United Kingdom) published new progress about Biaryls Role: SPN (Synthetic Preparation), PREP (Preparation). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, SDS of cas: 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhao, Qiang published the artcileRadical α-addition involved electrooxidative [3 + 2] annulation of phenols and electron-deficient alkenes, Application In Synthesis of 121-00-6, the main research area is phenol alkene electrooxidative regioselective diastereoselective cycloaddition; aryl dihydrobenzofuran preparation green chem.

An electrooxidative [3 + 2] annulation of phenols and electron-deficient alkenes for the synthesis of C3-functionalized 2-aryl-2,3-dihydrobenzofuran derivatives was achieved. The ring construction started by a unique α-addition of carbon radicals derived from anodic oxidation of phenols to electron-deficient alkenes. The subsequent anodic oxidation of the resulting alkyl radical intermediates followed by trapping with the phenolic hydroxy group assembles the 2,3-dihydrobenzofuran core. Such a pathway enabled the installation of various electrophilic functionalities including alkoxycarbonyl, alkylaminocarbonyl, trifluoromethyl, and cyano groups at the C-3 of the 2,3-dihydrobenzofuran framework, which is unattainable by other intermol. reactions. The application of this method for a rapid synthesis of a bioactive natural product was demonstrated.

Chemical Science published new progress about [3+2] Cycloaddition reaction, stereoselective (electrochem.). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Application In Synthesis of 121-00-6.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Bin published the artcileVolatile-char interactions during biomass pyrolysis Effect of char preparation temperature, Recommanded Product: 4-Hydroxy-3-tert-butylanisole, the main research area is volatile char interactions biomass cellulose pyrolysis.

In this study, the effect of char preparation temperature on the interactions between cellulose volatiles and acid-washed sawdust char was investigated exptl. on a fixed-bed pyrolysis system. The results indicated that significant volatile-char interactions did exist at the pyrolysis temperature of 500 °C as evidenced by the great changes in the composition and distribution of pyrolysis products. The oxygen-containing functional groups as well as the aromatic ring systems in the char both acted as active sites during the volatile-char interactions. The changes in chem. structure of biochar caused by the different preparation temperatures would notably affect the final products of cellulose pyrolysis. Meanwhile, the acid-washed sawdust char was still found to participate in the reaction process, lower temperature chars would have higher reactivities, and an obvious weight loss of char was also observed after interactions. In addition, volatile-char interactions significantly increased the yields of non-condensable gases, especially those of CO and CO2, while decreased the yield of condensable vapors. The introduction of biochar into cellulose pyrolysis could promote the ring scission of pyranoses as well as the decarbonylation/decarboxylation and dehydration reactions, thus caused the yields of anhydrosugars and monoarom. compounds decreased and the yields of light ketones and acids increased.

Energy (Oxford, United Kingdom) published new progress about Acids Role: IMF (Industrial Manufacture), PREP (Preparation). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Recommanded Product: 4-Hydroxy-3-tert-butylanisole.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Fan, Qingqing published the artcileNickel-Catalyzed Sonogashira Coupling Reactions of Nonactivated Alkyl Chlorides under Mild Conditions, Safety of (2-Chloroethoxy)benzene, the main research area is nickel catalyzed Sonogashira coupling reaction nonactivated alkyl halide alkyne; bidentate phosphinobenzenethiol phosphinobenzeneselenol nickel chelate preparation Sonogashira catalyst; crystal structure bidentate phosphinobenzenethiol nickel chloride chelate; mol structure bidentate phosphinobenzenethiol nickel chloride chelate.

The two Ni chlorides 1 and 2 with [P,S] and [P,Se] bidentate ligands, resp., were synthesized and used as catalysts for Sonogashira coupling reaction. Both 1 and 2 are efficient catalysts for Sonogashira C(sp3)-C(sp) coupling reactions. Complex 1 has better catalytic activity than complex 2. In a combination of 1 mol % catalyst loading of 1 and CuI/Cs2CO3/DMSO at 25° for the coupling reactions of alkyl iodides with terminal alkynes, the corresponding coupling products were obtained in moderate to excellent yields. This catalytic system is also suitable for alkyl bromides at 40°. It must be pointed out that with NaI as an additive complex 1 could effectively catalyze the C(sp3)-C(sp) coupling of nonactivated alkyl chlorides with alkynes under mild conditions (50°) with low catalyst loading (1 mol %). Complex 1 is easy to synthesize and has efficient catalytic activity, especially for alkyl chlorides, under mild conditions.

Organometallics published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Safety of (2-Chloroethoxy)benzene.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wang, Zijing published the artcileSonogashira reactions of alkyl halides catalyzed by NHC [CNN] pincer nickel(II) complexes, Safety of (2-Chloroethoxy)benzene, the main research area is nickel CNN pincer NHC carbene complex preparation Sonogashira catalyst; Sonogashira coupling catalyst nickel carbene pincer complex preparation; crystal structure nickel CNN pincer imidazolylidene carbene complex; mol structure nickel CNN pincer imidazolylidene carbene complex.

CNN-Pincer carbene nickel complexes I (6-8; R = iPr, Bu, PhCH2; X = Cl Br) were prepared and evaluated as catalysts for Sonogashira coupling of alkyl halides. The catalytic performance of complexes 6-8 for Sonogashira cross-coupling reactions was explored. In a combination of 5 mol% catalyst loading of 6 and CuI/Cs2CO3/NaI/DMSO at different temperatures for the coupling reactions between alkyl iodides, bromides, chlorides and terminal alkynes, the corresponding coupling products were obtained in moderate to excellent yields. The mechanism of these catalytic reactions was discussed and partially supported by experiments The phenylethynyl CNN pincer nickel complex 9 as a catalytically active complex was isolated and structurally characterized using X-ray diffraction.

New Journal of Chemistry published new progress about Alkynes, internal Role: SPN (Synthetic Preparation), PREP (Preparation). 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Safety of (2-Chloroethoxy)benzene.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Iu, Leo published the artcileHigh iso Aldehyde Selectivity in the Hydroformylation of Short-Chain Alkenes, Product Details of C11H16O2, the main research area is iso aldehyde selectivity hydroformylation alkene rhodium phospholane phosphite catalyst; enantioselective catalysis; fluorinated solvents; hydroformylation; phosphorus ligands; rhodium.

The hydroformylation of propene to give predominantly iso-butanal was achieved; class-leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic Rh complexes of bidentate phospholane phosphites derived from tropos-biphenols and unusual solvent systems are the key to the selectivity observed

Angewandte Chemie, International Edition published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation) (iso). 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Product Details of C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem