Extended knowledge of Benzyl ether

About Benzyl ether, If you have any questions, you can contact Si, XG; Zhao, YP; Song, QL; Cao, JP; Wang, RY; Wei, XY or concate me.. COA of Formula: C14H14O

In 2020 REACT CHEM ENG published article about NITROGEN-DOPED CARBON; HYDRODEOXYGENATION; EFFICIENT; NANOPARTICLES; CLEAVAGE; MODEL; RU; DEPOLYMERIZATION; HYDROGENATION; PERFORMANCE in [Si, Xing-Gang; Zhao, Yun-Peng; Song, Qing-Lu; Cao, Jing-Pei; Wei, Xian-Yong] China Univ Min & Technol, Minist Educ, Key Lab Coal Proc & Efficient Utilizat, Xuzhou 221114, Jiangsu, Peoples R China; [Zhao, Yun-Peng] Taiyuan Univ Technol, State Key Lab Breeding Base Coal Sci & Technol Co, Taiyuan 030024, Peoples R China; [Zhao, Yun-Peng] Taiyuan Univ Technol, Minist Sci & Technol, Taiyuan 030024, Peoples R China; [Wang, Rui-Yu] China Univ Min & Technol, Low Carbon Energy Inst, Xuzhou 221008, Jiangsu, Peoples R China in 2020, Cited 43. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4. COA of Formula: C14H14O

A highly efficient Ni/N-C catalyst was synthesized by facile pyrolysis of a Ni-containing metal-organic framework (Ni-MOF), and its catalytic hydrogenolysis performance towards C-O bonds in lignin was evaluated in detail using diphenyl ether (DPE) as a model compound. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analyses show that the flower-like nanosheets of the Ni-MOF shrink, forming a loose and ordered spherical structure during pyrolysis. Under the optimal conditions, DPE was completely converted and the selectivity to monomers (benzene, cyclohexanol and cyclohexane) reached 99.1%. During the catalytic hydrogenolysis conversion (CHC) of DPE, the direct cleavage of the C-aromatic-O bond affording benzene and phenol is the major reaction pathway, and a low H2 pressure is crucial to increase the monomer selectivity. Furthermore, Ni/N-C-450 shows high hydrogenolysis activity for other lignin-derived aryl ethers, such as benzyl phenyl ether, dibenzyl ether, dinaphthalene ether, benzyl 2-naphthyl ether and 3-methoxyphenol.

About Benzyl ether, If you have any questions, you can contact Si, XG; Zhao, YP; Song, QL; Cao, JP; Wang, RY; Wei, XY or concate me.. COA of Formula: C14H14O

Reference:
Ether – Wikipedia,
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Why do aromatic interactions matter of compound:101-84-8

About Diphenyl oxide, If you have any questions, you can contact Ontiveros-Cuadras, JF; Ruiz-Fernandez, AC; Sanchez-Cabeza, JA; Sericano, J; Perez-Bernal, LH; Paez-Osuna, F; Dunbar, RB; Mucciarone, DA or concate me.. Recommanded Product: Diphenyl oxide

An article Recent history of persistent organic pollutants (PAHs, PCBs, PBDEs) in sediments from a large tropical lake WOS:000461270900030 published article about POLYCYCLIC AROMATIC-HYDROCARBONS; HEAVY-METALS; RIVER-BASIN; CHAPALA; MEXICO; EXPOSURE; VERACRUZ; POPS; GULF; CONTAMINATION in [Feliciano Ontiveros-Cuadras, Jorge; Sanchez-Cabeza, Joan-Albert] Univ Nacl Autonoma Mexico, Inst Ciencias Mar & Limnol, Unidad Acad Proc Ocean & Costeros, Ciudad Univ, Mexico City 04510, DF, Mexico; [Carolina Ruiz-Fernandez, Ana; Hascibe Perez-Bernal, Libia; Paez-Osuna, Federico] Univ Nacl Autonoma Mexico, Inst Ciencias Mar & Limnol, Unidad Acad Mazatlan, Mazatlan 82040, Mexico; [Sericano, Jose] Texas A&M Univ, Geochem & Environm Res Grp, 833 Graham Rd, College Stn, TX 77845 USA; [Dunbar, Robert B.; Mucciarone, David A.] Stanford Univ, Earth Syst Sci, Stanford, CA 94305 USA in 2019.0, Cited 74.0. Recommanded Product: Diphenyl oxide. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8

Pb-210-dated sediment cores and surface sediments from Lake Chapala (LC), Mexico, were analyzed to assess the temporal trends in concentrations and fluxes of persistent organic pollutants (POPs: PAHs, PCBs and PBDEs). Total sediment concentrations of PAHs (95-1,482 ng g(-1)), PCBs (9-27 ng g(-1)) and PBDEs (0.2-2.5 ng g(-1)) were indicative of moderate to intense contamination. The POP concentrations have progressively increased since the 1990s. The light molecular weight PAHs, and the prevalence of PCB congeners with low-chlorination levels (e.g., di- to tri-CB) and low-to medium-brominated (tri- to penta-BDE) PBDEs in most sections of the sediment profiles, suggested that these POPs have most likely reached these sediments by long-range atmospheric transport from distant sources; although the significant presence of heavier PAH, PCB and PBDE congeners in the topmost sediments, indicate that other nearby and local sources (soil erosion from the catchment, urban and industrial wastewaters discharges, as well as navigation) might have also contributed to the recent input of POPs to LC. Taking into account the relevance of LC as regional freshwater supply and commercial fishing ground, the potential risk posed by the organic contaminated sediments to the biota and human population should not be underestimated.

About Diphenyl oxide, If you have any questions, you can contact Ontiveros-Cuadras, JF; Ruiz-Fernandez, AC; Sanchez-Cabeza, JA; Sericano, J; Perez-Bernal, LH; Paez-Osuna, F; Dunbar, RB; Mucciarone, DA or concate me.. Recommanded Product: Diphenyl oxide

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

What unique challenges do researchers face in C12H10O

About Diphenyl oxide, If you have any questions, you can contact Ding, Y; Zhang, SY; Chen, YC; Fan, SX; Tian, JS; Loh, TP or concate me.. HPLC of Formula: C12H10O

I found the field of Chemistry very interesting. Saw the article Regioselective C-H Amidation of (Alkyl)arenes by Iron(II) Catalysis published in 2019. HPLC of Formula: C12H10O, Reprint Addresses Tian, JS; Loh, TP (corresponding author), Nanjing Tech Univ NanjingTech, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, SCME, IAS, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China.; Loh, TP (corresponding author), Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore.; Loh, TP (corresponding author), Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China.. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide

A nondirected amidation reaction of aromatic C-H bond was developed under iron(II) catalysis, using sulfonyl azides as the nitrogen source. The reaction displayed a broad substrate scope and good regioselectivities in the aspects of aromatic ring vs alkyl chain and different aromatic position of (alkyl)arenes. This method provided a new protocol for the synthesis of some aromatic amines, which were hard to achieve in a previous report.

About Diphenyl oxide, If you have any questions, you can contact Ding, Y; Zhang, SY; Chen, YC; Fan, SX; Tian, JS; Loh, TP or concate me.. HPLC of Formula: C12H10O

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Discovery of C14H14O

Application In Synthesis of Benzyl ether. About Benzyl ether, If you have any questions, you can contact Schneidereit, D; Brollochs, A; Ritter, P; Kreiss, L; Mokhtari, Z; Beilhack, A; Kronke, G; Ackermann, JA; Faas, M; Gruneboom, A; Schurmann, S; Friedrich, O or concate me.

Recently I am researching about 2ND-HARMONIC GENERATION; SHG MICROSCOPY; SKELETAL-MUSCLE; HIGH-RESOLUTION; MICROARCHITECTURE; REGENERATION; MORPHOMETRY; EXCITATION, Saw an article supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)German Research Foundation (DFG) [326998133 -TRR225]. Published in IVYSPRING INT PUBL in LAKE HAVEN ,Authors: Schneidereit, D; Brollochs, A; Ritter, P; Kreiss, L; Mokhtari, Z; Beilhack, A; Kronke, G; Ackermann, JA; Faas, M; Gruneboom, A; Schurmann, S; Friedrich, O. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether. Application In Synthesis of Benzyl ether

Rationale: Structural remodeling or damage as a result of disease or injury is often not evenly distributed throughout a tissue but strongly depends on localization and extent of damaging stimuli. Skeletal muscle as a mechanically active organ can express signs of local or even systemic myopathic damage, necrosis, or repair. Conventionally, muscle biopsies (patients) or whole muscles (animal models) are mechanically sliced and stained to assess structural alterations histologically. Three-dimensional tissue information can be obtained by applying deep imaging modalities, e.g. multiphoton or light-sheet microscopy. Chemical clearing approaches reduce scattering, e.g. through matching refractive tissue indices, to overcome optical penetration depth limits in thick tissues. Methods: Here, we optimized a range of different clearing protocols. We find aqueous solution-based protocols employing (20-80%) 2,2′-thiodiethanol (TDE) to be advantageous over organic solvents (dibenzyl ether, cinnamate) regarding the preservation of muscle morphology, ease-of-use, hazard level, and costs. Results: Applying TDE clearing to a mouse model of local cardiotoxin (CTX)-induced muscle necrosis, a complete loss of myosin-II signals was observed in necrotic areas with little change in fibrous collagen or autofluorescence (AF) signals. The 3D aspect of myofiber integrity could be assessed, and muscle necrosis in whole muscle was quantified locally via the ratios of detected AF, forward- and backward-scattered Second Harmonic Generation (fSHG, bSHG) signals. Conclusion: TDE optical clearing is a versatile tool to study muscle architecture in conjunction with label-free multiphoton imaging in 3D in injury/myopathy models and might also be useful in studying larger biofabricated constructs in regenerative medicine.

Application In Synthesis of Benzyl ether. About Benzyl ether, If you have any questions, you can contact Schneidereit, D; Brollochs, A; Ritter, P; Kreiss, L; Mokhtari, Z; Beilhack, A; Kronke, G; Ackermann, JA; Faas, M; Gruneboom, A; Schurmann, S; Friedrich, O or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Interesting scientific research on Benzyl ether

About Benzyl ether, If you have any questions, you can contact Lachowicz, D; Wirecka, R; Gorka-Kumik, W; Marzec, MM; Gajewska, M; Kmita, A; Zukrowski, J; Sikora, M; Zapotoczny, S; Bernasik, A or concate me.. SDS of cas: 103-50-4

An article Gradient of zinc content in core-shell zinc ferrite nanoparticles – precise study on composition and magnetic properties WOS:000495070100019 published article about IRON-OXIDE NANOPARTICLES; FE3O4 NANOPARTICLES; X-RAY; SIZE; TEMPERATURE; FERROFLUID; MORPHOLOGY; RANGE; XPS in [Lachowicz, Dorota; Marzec, Mateusz Marek; Gajewska, Marta; Kmita, Angelika; Zukrowski, Jan; Sikora, Marcin] AGH Univ Sci & Technol, Acad Ctr Mat & Nanotechnol, Al A Mickiewicza 30, PL-30059 Krakow, Poland; [Wirecka, Roma; Bernasik, Andrzej] AGH Univ Sci & Technol, Fac Phys & Appl Comp Sci, Al A Mickiewicza 30, PL-30059 Krakow, Poland; [Gorka-Kumik, Weronika] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, Prof Stanislawa Lojasiewicza 11, PL-30348 Krakow, Poland; [Zapotoczny, Szczepan] Jagiellonian Univ, Fac Chem, Gronostajowa 2, PL-30387 Krakow, Poland in 2019, Cited 66. The Name is Benzyl ether. Through research, I have a further understanding and discovery of 103-50-4. SDS of cas: 103-50-4

A broad spectrum of applications of magnetic nanoparticles leads to the need for the precise tuning of their magnetic properties. In this study, a series of magnetite and zinc-ferrite nanoparticles were successfully prepared by modified high-temperature synthesis in a controlled gas atmosphere. Nanoparticles with different zinc to iron ratios and pure Fe3O4 were obtained. The structure of the nanoparticles was studied by transmission electron microscopy and Mossbauer spectroscopy. These revealed the single domain character of the nanoparticles and the influence of the synthesis temperature and zinc to iron ratio on their shape and size. Chemical structure was characterized by inductively coupled plasma optical emission spectroscopy, energy dispersive X-ray spectroscopy and thermogravimetric analysis. X-ray photoelectron spectroscopy coupled with an argon gas cluster ion beam (Ar-GCIB) allowed the study of subsequent layers of the nanoparticles without altering their chemical structure. This revealed the presence of a carbon layer on all nanoparticles consisting of capping agents used in the synthesis and revealed the core-shell character of the zinc ferrite particles. In addition, different types of zinc infusions in the nanoparticle structure were observed when using different Zn/Fe ratios. Finally, magnetic studies performed by means of vibrating sample magnetometry proved the superparamagnetic behavior of all the samples.

About Benzyl ether, If you have any questions, you can contact Lachowicz, D; Wirecka, R; Gorka-Kumik, W; Marzec, MM; Gajewska, M; Kmita, A; Zukrowski, J; Sikora, M; Zapotoczny, S; Bernasik, A or concate me.. SDS of cas: 103-50-4

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Top Picks: new discover of Benzyl ether

About Benzyl ether, If you have any questions, you can contact Xu, LJ; Yuan, YY; Zhang, J; Zhang, YF; Zhang, XM; Chen, L; Xu, L or concate me.. SDS of cas: 103-50-4

I found the field of Chemistry; Crystallography very interesting. Saw the article In situ fabrication of core-shell-structured Beta@Silicalite-1 catalysts by a novel steam-assisted crystallization strategy published in 2020. SDS of cas: 103-50-4, Reprint Addresses Yuan, YY; Xu, L (corresponding author), Chinese Acad Sci, Dalian Inst Chem Phys, Natl Lab Clean Energy, Dalian 116023, Peoples R China.. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether

A green, cost-effective and facile steam-assisted crystallization (SAC) strategy was developed to synthesize core-shell-structured zeolite composites with different frameworks between the core and shell. Chemical incompatibility from different structures has been circumvented by dip-coating Silicalite-1 seeds and an in situ transformation process. Beta@Silicalite-1 zeolites with a nanoscale polycrystal Silicalite-1 shell wrapped around the monocrystal Beta core was synthesized. The crystallization process and synthetic parameters, such as the composition of the core, crystallization temperature and gel composition of the seed solution, were investigated. The results revealed the importance of stability of the core and the crystallization rate of the Silicalite-1 shell. Interestingly, a trace amount of aluminum in the core zeolite could help resist corrosion during crystallization. Further investigation on alkylation and etherification reactions over Beta@Silicalite-1 demonstrated the advantage in selectivity control toward self-etherification versus alkylation.

About Benzyl ether, If you have any questions, you can contact Xu, LJ; Yuan, YY; Zhang, J; Zhang, YF; Zhang, XM; Chen, L; Xu, L or concate me.. SDS of cas: 103-50-4

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Something interesting about Diphenyl oxide

HPLC of Formula: C12H10O. About Diphenyl oxide, If you have any questions, you can contact Yakovlev, IG; Garkushin, IK; Kolyado, AV or concate me.

In 2020.0 RUSS J PHYS CHEM A+ published article about BINARY-MIXTURES; DENSITY in [Yakovlev, I. G.; Garkushin, I. K.; Kolyado, A., V] Samara State Tech Univ, Samara 443001, Russia in 2020.0, Cited 19.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. HPLC of Formula: C12H10O

A theoretical and experimental study is performed for liquid-solid phase equilibria in the two-component diphenyl oxide-n-hexadecane system. The results show that this system is eutectic. Two means are chosen for the theoretical study of the system: the Schroder-Le Chatelier equations and the original UNIFAC system. Experimental studies are made via differential thermal analysis on a DSC unit. Results from the theoretical and experimental studies are presented in the formT-xdiagrams of the system. The theoretical and experimental data are compared to one another. Each way of calculating is assessed, and recommendations are made for their application. The eutectic coordinates (melting point and composition) are determined experimentally. The following values are determined experimentally for a eutectic melt: the enthalpy of melting; density at 25 degrees C; kinematic viscosity in the temperature range of 25 to 50 degrees C; flash point in an open cup; boiling point, and refractive index in the temperature range of 25 to 40 degrees C. The composition of the eutectic melt can be used in industry as a heat transfer fluid.

HPLC of Formula: C12H10O. About Diphenyl oxide, If you have any questions, you can contact Yakovlev, IG; Garkushin, IK; Kolyado, AV or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Can You Really Do Chemisty Experiments About 103-50-4

SDS of cas: 103-50-4. About Benzyl ether, If you have any questions, you can contact Khawaji, M; Chadwick, D or concate me.

I found the field of Chemistry; Engineering very interesting. Saw the article Selective catalytic oxidation over Au-Pd/titanate nanotubes and the influence of the catalyst preparation method on the activity published in 2019. SDS of cas: 103-50-4, Reprint Addresses Chadwick, D (corresponding author), Imperial Coll London, Dept Chem Engn, London SW7 2AZ, England.. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether

The dependence of the selective oxidation catalytic activity of Au-Pd supported on titanate nanotubes on the catalyst preparation method has been investigated. The most active Au-Pd/Ti-NT catalyst for the selective oxidation of benzyl alcohol is shown to be that prepared using colloidal synthesis and immobilization with PVA as a stabilizer, which has markedly superior catalytic activity compared to catalysts prepared by deposition-precipitation, adsorption, and dry impregnation methods. Au-Pd NPs stabilized by graphene oxide sheets and immobilized on Ti-NT has also been studied and while not optimum shows promising catalytic activity. The superior catalytic activity of the catalysts prepared by colloidal synthesis is attributed to the high metal dispersion on the external surfaces of Ti-NT, the narrow particle size distribution, and the high degree of Au-Pd alloying. This work also demonstrates that in the adsorption method of preparation using HAuCl4.3H(2)O and PdCl2 precursors, the uptake of Pd ions in solution by Ti-NT is proportional to the sodium content in Ti-NT, which implies that Na is involved in an ion-exchange reaction with Pd ions.

SDS of cas: 103-50-4. About Benzyl ether, If you have any questions, you can contact Khawaji, M; Chadwick, D or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

More research is needed about C12H10O

About Diphenyl oxide, If you have any questions, you can contact Zanuttini, C; Gally, F; Scholl, G; Thome, JP; Eppe, G; Das, K or concate me.. COA of Formula: C12H10O

An article High pollutant exposure level of the largest European community of bottlenose dolphins in the English Channel WOS:000485216500001 published article about PORPOISES PHOCOENA-PHOCOENA; TOXIC EQUIVALENCY FACTORS; POLYBROMINATED DIPHENYL ETHERS; PERSISTENT ORGANIC POLLUTANTS; TURSIOPS-TRUNCATUS; POLYCHLORINATED-BIPHENYLS; NORTH-SEA; LIFETIME EXPOSURE; SOCIAL-STRUCTURE; RISK-ASSESSMENT in [Zanuttini, Cyrielle; Gally, Francois] GECC, Pl Justes, F-50130 Octeville, France; [Scholl, Georges; Eppe, Gauthier] Univ Liege, UR MolSys B6c, CART, B-4000 Liege, Belgium; [Thome, Jean-Pierre] Univ Liege, CART LEAE, Freshwater & Ocean Sci Unit reS FOCUS CART LEAE, B6C, Liege, Belgium; [Das, Krishna] Univ Liege, B6C, Freshwater & Ocean Sci Unit reS FOCUS Oceanol, Liege, Belgium in 2019.0, Cited 48.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. COA of Formula: C12H10O

The objective of this study was to assess the levels of persistent organic pollutants (POPs) and mercury (T-Hg) in the blubber and skin, respectively, of the free-ranging bottlenose dolphins, Tursiops truncatus, from the Normanno-Breton Gulf, one of the largest identified coastal population in Europe. Among all the POPs analysed in this study, the Sigma NDL-PCBs were the most abundant compounds found in the blubber (mean: 1.33 x 10(5) -0.65 x 10(5) ng.g(-1) lipid weight (lw) for males and females respectively), followed by Sigma DDX (1.11 x 10(4) -4.67 x 10(3) ng.g(-1 )lw) > Sigma DL-PCBs (8.06 x 10(3)-2.62 x 10(3) ng.g(-1 )lw) >Sigma PBDEs (1.95 x 10(3) -0.64 x 10(3) ng.g(-1) lw) > dieldrin (1.86 x 10(3)-0.18 x 10(3) ng.g(-1 )lw) >Sigma endosulfan (405-62 ng.g(-1 )lw) > HCB (86-52 ng.g(-1 )lw) > Sigma HCHs (47-60 ng. g(-1) lw) >Sigma chlordane (24-0.97 ng.g(-1 )lw) >Sigma PCDFs (0.3-0.1 ng.g(-1 )lw) >Sigma PCDDs (0.06-0.05 ng.g(-1) lw). The T-Hg concentrations were highly variable between individuals (2.45 x 10(3) ng.g(-1) to 21.3 x 10(3) ng.g(-1) dry weight, dw). The reported concentrations are among the highest reported for cetaceans. We strongly recommend that the Normanno-Breton Gulf be a special area of conservation (cSAC) candidate because it contains the last large European population of bottlenose dolphins (rare or threatened within a European context) designated under the EC Habitats Directive.

About Diphenyl oxide, If you have any questions, you can contact Zanuttini, C; Gally, F; Scholl, G; Thome, JP; Eppe, G; Das, K or concate me.. COA of Formula: C12H10O

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem

Our Top Choice Compound:C12H10O

HPLC of Formula: C12H10O. About Diphenyl oxide, If you have any questions, you can contact Oda, S; Ueura, K; Kawakami, B; Hatakeyama, T or concate me.

An article Multiple Electrophilic C-H Borylation of Arenes Using Boron Triiodide WOS:000508468200074 published article about DELAYED FLUORESCENCE MOLECULES; CATALYZED DIRECT BORYLATION; CROSS-COUPLING REACTIONS; AROMATIC-HYDROCARBONS; OPTICAL-PROPERTIES; ANTIFUNGAL AGENT; LEWIS-ACID; ACTIVATION; REMOTE; FUNCTIONALIZATION in in 2020.0, Cited 97.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8. HPLC of Formula: C12H10O

Electrophilic C-H borylation of arenes using boron triiodide has been developed. This reaction proceeded smoothly in the absence of additives, and the diiodoboryl group was installed at the most sterically accessible carbon, where the HOMO is localized to a certain extent. Moreover, regioselective multiple borylation of polycyclic aromatic compounds was achieved by using excess boron triiodide. The borylated intermediates were transformed into a variety of arylboron compounds such as arylboronates, boronic acids, and trifluoroborates.

HPLC of Formula: C12H10O. About Diphenyl oxide, If you have any questions, you can contact Oda, S; Ueura, K; Kawakami, B; Hatakeyama, T or concate me.

Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem