Month: October 2022

In 2019,Molecules (Basel, Switzerland) included an article by Chen, Ichen; Xu, Chenxi; Peng, Jing; Han, Dong; Liu, Siqi; Zhai, Maolin. Electric Literature of C10H20O5. The article was titled 《Novel Functionalized Cellulose Microspheres for Efficient Separation of Lithium Ion and Its Isotopes: Synthesis and Adsorption Performance.》. The information in the text is summarized as follows:

The adsorption of lithium ions(Li+) and the separation of lithium isotopes have attracted interests due to their important role in energy storage and nuclear energy, respectively. However, it is still challenging to separate the Li+ and its isotopes with high efficiency and selectivity. A novel cellulose-based microsphere containing crown ethers groups (named as MCM-g-AB15C5) was successfully synthesized by pre-irradiation-induced emulsion grafting of glycidyl methacrylate (GMA) and followed by the chemical reaction between the epoxy group of grafted polymer and 4′-aminobenzo-15-crown-5 (AB15C5). By using MCM-g-AB15C5 as adsorbent, the effects of solvent, metal ions, and adsorption temperature on the adsorption uptake of Li+ and separation factor of 6Li/7Li were investigated in detail. Solvent with low polarity, high adsorption temperature in acetonitrile could improve the uptake of Li+ and separation factor of lithium isotopes. The MCM-g-AB15C5 exhibited the strongest adsorption affinity to Li+ with a separation factor of 1.022 ± 0.002 for 6Li/7Li in acetonitrile. The adsorption isotherms in acetonitrile is fitted well with the Langmuir model with an ultrahigh adsorption capacity up to 12.9 mg·g-1, indicating the unexpected complexation ratio of 1:2 between MCM-g-AB15C5 and Li+. The thermodynamics study confirmed the adsorption process is the endothermic, spontaneous, and chemisorption adsorption. As-prepared novel cellulose-based adsorbents are promising materials for the efficient and selective separation of Li+ and its isotopes. In the experiment, the researchers used many compounds, for example, 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Electric Literature of C10H20O5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Electric Literature of C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Advanced Synthesis & Catalysis included an article by Kim, Seongwoo; Kim, Youngik; Jin, Hyomin; Park, Myung Hwan; Kim, Youngjo; Lee, Kang Mun; Kim, Min. Computed Properties of C8H8O2. The article was titled 《Europium-catalyzed aerobic oxidation of alcohols to aldehydes/ketones and photoluminescence tracking》. The information in the text is summarized as follows:

Europium-catalyzed aerobic oxidation of alcs. to aldehydes/ketones with external catalytic oxidants utilizing the redox cycle of Eu2+/Eu3+ was developed. The oxidation reaction was performed under mild conditions and it showed good substrate tolerance. The photoluminescence spectra clearly demonstrated the oxidation state changes that occur during the presented europium-catalyzed aerobic oxidation In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Computed Properties of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Computed Properties of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organic & Biomolecular Chemistry included an article by Takagi, Mio; Watanabe, Ayako; Murata, Shigeo; Takita, Ryo. Formula: C7H7IO. The article was titled 《Copper-catalyzed arene amination in pure aqueous ammonia》. The information in the text is summarized as follows:

A simple protocol for copper-catalyzed arene amination using aqueous ammonia without any addnl. ligands and organic coordinating solvents has been developed. The reaction pathway via a Cu(I)/Cu(III) mechanism is proposed based on the results of control experiments as well as DFT calculations After reading the article, we found that the author used 1-Iodo-2-methoxybenzene(cas: 529-28-2Formula: C7H7IO)

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Formula: C7H7IO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Advanced Synthesis & Catalysis included an article by Ruan, Hongjie; Meng, Ling-Guo; Zhu, Lingqiong; Wang, Lei. Related Products of 882-33-7. The article was titled 《Visible-Light-Induced Hydroxysulfurization and Alkoxysulfurization of Styrenes in the Absence of Photocatalyst: Synthesis of β-Hydroxysulfides and β-Alkoxysulfides》. The information in the text is summarized as follows:

Hydroxysulfurization and alkoxysulfurization of styrenes using a visible-light synthetic strategy in the absence of photocatalyst and oxidant was devoleped. This strategy provided the corresponding β-hydroxysulfides and β-alkoxysulfides in moderate to good yields with high regioselectivity. The reaction was tolerated by a wide range of functional groups. This is the first example of ArSSAr/CBr4 system was introduced into organic transformation. The experimental process involved the reaction of 1,2-Diphenyldisulfane(cas: 882-33-7Related Products of 882-33-7)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.The C-O bonds that comprise simple ethers are strong. Related Products of 882-33-7 They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Computationally Assisted Mechanistic Investigation into Hypervalent Iodine Catalysis: Cyclization of N-Allylbenzamide》 were Butt, Smaher E.; Das, Mirdyul; Sotiropoulos, Jean-Marc; Moran, Wesley J.. And the article was published in Journal of Organic Chemistry in 2019. Application of 529-28-2 The author mentioned the following in the article:

Previous exptl. work identified 2-iodoanisole as the best precatalyst for the oxidative cyclization of N-alkenylamides into 2-oxazolines. Herein, we describe our investigation into the effect on reaction rate based on the structure of the iodoarene precatalyst. We also reveal the mechanism of the cyclization based on DFT modeling and obtain a clear correlation between observed reaction rates and computationally derived activation energies for different iodoarenes. In addition, the rate-limiting step is shown to be the cyclization of the substrate which is zero order in the concentration of the iodoarene precatalyst. The rate of the cyclization is found to correlate with the ease of oxidation of the iodoarene, however the most easily oxidized iodoarenes generate iodine(III) species that decompose readily. Finally, loss of iodoarene from the cyclized intermediate can proceed by either ligand-coupling or SN2 displacement (reductive elimination), and this is shown to be substrate dependent. After reading the article, we found that the author used 1-Iodo-2-methoxybenzene(cas: 529-28-2Application of 529-28-2)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Application of 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Mechanochemical Pd(II)-Catalyzed Direct and C-2-Selective Arylation of Indoles》 were Das, Dharmendra; Bhutia, Zigmee T.; Chatterjee, Amrita; Banerjee, Mainak. And the article was published in Journal of Organic Chemistry in 2019. Safety of 1-Iodo-2-methoxybenzene The author mentioned the following in the article:

A mechanochem. method for the preparation of synthetically useful 2-arylindoles is developed using Pd(II) as the catalyst in the absence of phosphine ligands in a ball-mill. The developed protocol is highly C-2 selective and tolerant of structural variations with electron-rich and electron-deficient substituents both in indoles and iodoarenes. Arylation is possible in both unprotected indoles and N-protected indoles with the electron-donating group with the former substrate being relatively slower to react and little less yielding. Indoles with a deactivated five-membered ring could also take part in the reaction with ease. The scalability of the reaction was demonstrated by conducting the reaction in the gram scale. In general, the reactions were achieved in a shorter time than the conventional methods. The experimental process involved the reaction of 1-Iodo-2-methoxybenzene(cas: 529-28-2Safety of 1-Iodo-2-methoxybenzene)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Safety of 1-Iodo-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《A peri-xanthenoxanthene centered columnar-stacking organic semiconductor for efficient, photothermally stable perovskite solar cells》 were Xu, Niansheng; Li, Yang; Wu, Ruihan; Zhu, Rui; Zhang, Jidong; Zakeeruddin, Shaik M.; Li, Hanying; Li, Ze-Sheng; Graetzel, Michael; Wang, Peng. And the article was published in Chemistry – A European Journal in 2019. Application In Synthesis of Bis(4-methoxyphenyl)amine The author mentioned the following in the article:

Modulating the structure and property of hole-transporting organic semiconductors is of paramount importance for high-efficiency and stable perovskite solar cells (PSCs). This work reports a low-cost peri-xanthenoxanthene based small-mol. P1, which is prepared at a total yield of 82% using a 3-step synthetic route from the low-cost starting material 2-naphthol. P1 mols. stack in 1-dimensional columnar arrangement characteristic of strong intermol. π-π interactions, contributing to the formation of a solution-processed, semicrystalline thin-film exhibiting one order of magnitude higher hole mobility than the amorphous one based on the state-of-the art hole-transporter, 2,2-7,7-tetrakis(N,N’-di-paramethoxy-phenylamine 9,9′-spirobifluorene) (spiro-OMeTAD). PSCs employing P1 as the hole-transporting layer attain a high efficiency of 19.8% at the standard AM 1.5 G conditions, and good long-term stability under continuous full sunlight exposure at 40°C. The experimental part of the paper was very detailed, including the reaction process of Bis(4-methoxyphenyl)amine(cas: 101-70-2Application In Synthesis of Bis(4-methoxyphenyl)amine)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.Application In Synthesis of Bis(4-methoxyphenyl)amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Bis(diphenylamine)-Tethered Carbazolyl Anthracene Derivatives as Hole-Transporting Materials for Stable and High-Performance Perovskite Solar Cells》 was published in ACS Applied Energy Materials in 2020. These research results belong to Singh, Ashutosh; Abate, Seid Yimer; Pavan Kumar, Ch.; Wu, Wen-Ti; Hsiao, Jye-Chian; Wu, Feng-Ling; Lin, Jiann T’suen; Tao, Yu-Tai. COA of Formula: C14H15NO2 The article mentions the following:

Three new hole-transporting materials (HTMs), composed of N3,N6-bis(di-4-anisylamino)-9H-carbazole and anthracene moieties, have been developed for perovskite solar cell (PSC) application. Two of the new HTMs have better hole mobility and hole-extraction ability compared to spiro-OMeTAD. Accordingly, the best PSC based on mixed ion perovskite of Cs0.05FA0.79MA0.16PbI2.49Br0.51 and doped HTMs has better power conversion efficiency (18.65%) than the corresponding PSC based on doped spiro-OMeTAD (17.90%). Moreover, the PSCs based on these HTMs have negligible hysteresis and good temporal stability. The experimental process involved the reaction of Bis(4-methoxyphenyl)amine(cas: 101-70-2COA of Formula: C14H15NO2)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.COA of Formula: C14H15NO2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Long-Distance Chirality Transfer from P-Ligand to Prochiral Dihydrosilanes via Pd(II) Aryl Iodide Complex in Pd-Catalyzed Silylation of Aryl Iodide: A DFT Study》 was published in Journal of Organic Chemistry in 2020. These research results belong to Yang, Jing-Jing; Xu, Zheng; Nie, Yi-Xue; Lu, Si-Qi; Zhang, Jin; Xu, Li-Wen. Recommanded Product: 1-Iodo-2-methoxybenzene The article mentions the following:

The mechanism of Pd-catalyzed desym. monoarylation of dihydrosilanes with aryl iodides in the presence of chiral TADDOL-derived phosphoramidite ligand toward deeper understanding of the stereoselectivity has been investigated using hybrid d. functional theory (DFT) methodol. The full catalytic cycle for the favorable reaction pathway, which is initiated by the oxidative addition of aryl iodide to monoligated Pd0 leading to the silylation product, was calculated The DFT calculation results indicate that the enantio-discriminating transmetalation between Pd-Ar bond of the Pd(II) aryl iodide complex and Si-H bond of the prochiral dihydrosilane was the enantioselectivity-determining step. On the basis of the structure of the transition state, the attractive aryl-aryl interactions between the aryl group of ligand, aryl iodide, and dihydrosilane were found to play an important role for the chiral transference from the chiral ligand to asym. cleavage of the Si-H bond of the prochiral dihydrosilane. The results came from multiple reactions, including the reaction of 1-Iodo-2-methoxybenzene(cas: 529-28-2Recommanded Product: 1-Iodo-2-methoxybenzene)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Recommanded Product: 1-Iodo-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Miao, An-Qi; Zhou, Meng; Chen, Jing-Long; Wang, Shi-Chao; Hao, Wen-Juan; Tu, Shu-Jiang; Jiang, Bo published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Pd-Catalyzed Asymmetric Addition of Arylboronic Acids to Pyrazolinone Ketimines》.Formula: C7H9BO3 The article contains the following contents:

An asym. addition of arylboronic acids to pyrazolinone ketimines was reported using palladium/chiral N,N’-disulfonyl bisimidazoline (Bim) catalytic system, producing 25 examples of enantioenriched 4-amino-5-pyrazolones I [R1 = Ph, 4-FC6H4, 4-MeOC6H4, etc.; R2 = t-Bu, Ph, p-tolyl, etc.; Ar = Ph, 3-MeOC6H4, 4-BrC6H4, etc.; stereo = R] bearing one quaternary carbon stereocenter with 60-91% yields and 81-98% ee. The reaction demonstrated remarkable compatibility regarding pyrazolinone ketimines and arylboronic acids, rendering an enantioselective access to chiral aza-heterocycles bearing α-tertiary amines. In addition to this study using 3-Methoxyphenylboronic acid, there are many other studies that have used 3-Methoxyphenylboronic acid(cas: 10365-98-7Formula: C7H9BO3) was used in this study.

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Formula: C7H9BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem