Month: October 2022

On November 2, 2016, Le, Christine M.; Sperger, Theresa; Fu, Rui; Hou, Xiao; Lim, Yong Hwan; Schoenebeck, Franziska; Lautens, Mark published an article.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Stereoselective Synthesis of Methylene Oxindoles via Palladium(II)-Catalyzed Intramolecular Cross-Coupling of Carbamoyl Chlorides. And the article contained the following:

In the presence of PdCl2(PhCN)2 in toluene, arylalkynylphenylcarbamoyl chlorides such as I underwent regio- and stereoselective intramol. cross-coupling to yield chloromethyleneoxindoles such as II. The reaction proceeds under mild conditions, is insensitive to the presence of moisture and air, formed products in >95:5 Z:E selectivity in nearly all cases and is readily scalable. Product isomerization studies and calculations of the transition state structures and energies for pathways leading to product regioisomers and diastereomers were used to study the mechanism of the reaction. The calculations provide support for a mechanism involving oxidative addition into the carbamoyl chloride bond to generate a high valent PdIV species, which then undergoes facile C-C reductive elimination to form the final product. I underwent stereoselective substitution and Suzuki cross-coupling reactions. The structures of a (phenylchloromethylene)oxindole, a chlorophenylquinolinone byproduct, and the substitution product of II with benzylthiol were determined by X-ray crystallog. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Reference of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to chloromethylene oxindole regioselective diastereoselective preparation, palladium catalyst regioselective stereoselective cyclization arylalkynyl phenylcarbamoyl chloride, intramol regioselective stereoselective cross coupling arylalkynyl phenylcarbamoyl chloride and other aspects.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 7, 2021, Kim, Hyun Tae; Kang, Eunsu; Kim, Minkyu; Joo, Jung Min published an article.SDS of cas: 91-16-7 The title of the article was Synthesis of Bidentate Nitrogen Ligands by Rh-Catalyzed C-H Annulation and Their Application to Pd-Catalyzed Aerobic C-H Alkenylation. And the article contained the following:

A new class of bidentate ligands was prepared by a modular approach involving Rh-catalyzed C-H annulation reactions. The resulting conformationally constrained ligands enabled the Pd-catalyzed C-H alkenylation at electron-rich and sterically less hindered positions of electron-rich arenes while promoting the facile oxidation of Pd(0) intermediates by oxygen. This newly introduced ligand class was complementary to the ligands developed for Pd-catalyzed oxidative reactions and may find broad application in transition-metal-catalyzed reactions. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).SDS of cas: 91-16-7

The Article related to bidentate pyrazolonaphthyridine ligand palladium catalyst preparation, aryl amine terminal alkene pyrazolonaphthyridine palladium catalyst regioselective alkenylation, alkoxyarene terminal alkene pyrazolonaphthyridine palladium catalyst regioselective alkenylation and other aspects.SDS of cas: 91-16-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 7, 2021, Kim, Hyun Tae; Kang, Eunsu; Kim, Minkyu; Joo, Jung Min published an article.Related Products of 578-58-5 The title of the article was Synthesis of Bidentate Nitrogen Ligands by Rh-Catalyzed C-H Annulation and Their Application to Pd-Catalyzed Aerobic C-H Alkenylation. And the article contained the following:

A new class of bidentate ligands was prepared by a modular approach involving Rh-catalyzed C-H annulation reactions. The resulting conformationally constrained ligands enabled the Pd-catalyzed C-H alkenylation at electron-rich and sterically less hindered positions of electron-rich arenes while promoting the facile oxidation of Pd(0) intermediates by oxygen. This newly introduced ligand class was complementary to the ligands developed for Pd-catalyzed oxidative reactions and may find broad application in transition-metal-catalyzed reactions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Related Products of 578-58-5

The Article related to bidentate pyrazolonaphthyridine ligand palladium catalyst preparation, aryl amine terminal alkene pyrazolonaphthyridine palladium catalyst regioselective alkenylation, alkoxyarene terminal alkene pyrazolonaphthyridine palladium catalyst regioselective alkenylation and other aspects.Related Products of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 9, 2022, Xu, Ren-Rui; Bao, Xuanzhang; Huo, Yong-Wang; Miao, Ren-Guan; Wen, Dan; Dai, Weiqi; Qi, Xinxin; Wu, Xiao-Feng published an article.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Palladium-Catalyzed Domino Carbopalladation/Carbonylative Cyclization: Synthesis of Heterocycles bearing Oxindoles and 3-Acylbenzofuran/3-Acylindole Moieties. And the article contained the following:

A novel and straightforward methodol. for palladium-catalyzed carbopalladation-initiated domino carbonylative cyclization to construct bisheterocycles was established. With TFBen as an efficient and convenient CO source, the protocol wass capable of generating oxindole and 3-acylbenzofuran/3-acylindole moieties from the corresponding N-(o-iodoaryl)acrylamides and o-alkynylphenols/o-alkynylanilines with the formation of three C-C bonds and one C-O/C-N bond in a single one-step operation. A wide range of bisheterocycles bearing oxindoles and 3-acylbenzofurans/3-acylindoles were prepared in moderate to excellent yields with good functional group tolerance. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to iodophenyl acrylamide ethynylphenol tfben palladium tandem carbonylative heterocyclization, benzofuranyl oxindolyl ethanone preparation, ethynylaniline iodoaryl acrylamide tfben palladium tandem carbonylative heterocyclization, oxindolyl indolylethanone preparation and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 15, 1994, Wudl, Fred; Hoger, Sigurd published a patent.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene The title of the patent was Highly soluble, conductive, luminescent polyphenylenevinylenes, and products and uses thereof. And the patent contained the following:

Soluble, fast doping and de-doping, conductive, electroluminescent π-conjugated polymers I [R1 = H; hydrocarbyl, or OR3, R2 = H or Me, R3 = (mono- or polyhydroxy) branched C6-30 hydrocarbyl or C1-10 esters, C1-10 ethers, (poly)furanosyl, (poly)pyranosyl of the hydroxy derivatives; A is O, C, S, N or a single bond; n, m = 1-4; o = 1-2, x ≥ 1, y ≥ 0 and x + y > 20] are manufactured for use in electrostatic and electromagnetic interference shields, molded articles, and especially in electroluminescent layers, films and fibers for use in light-emitting diodes for tech. devices. A method for sensing a dopant within a designated area is described by exposing an amount of a dopant to ≥1 I. An improved method is described for transducing elec. energy into visible light by means of a light-emitting diode containing I. A typical polymer was manufactured by polymerization of 2,5-bis(chloromethyl)-1-methoxy-4-(2-ethylhexyloxy)benzene 24 h in THF in the presence of tert-BuOK. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to soluble elec conductive electroluminescent polyphenylenevinylene, electrostatic shield polyphenylenevinylene, bischloromethyl methoxyethylhexyloxybenzene polymer soluble elec conductive, electromagnetic shield polyphenylenevinylene, led device polyphenylenevinylene and other aspects.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 29, 2021, He, Yu-Ping; Cao, Jian; Wu, Hua; Wang, Qian; Zhu, Jieping published an article.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Catalytic Enantioselective Aminopalladation-Heck Cascade. And the article contained the following:

Domino processes initiated by intramol. nucleopalladation of alkynes have been developed into powerful synthetic tools for the synthesis of functionalized heterocycles. However, a catalytic enantioselective version of this class of reactions remains scarce. We report herein that reaction of 2-alkynylanilines with prochiral cyclopentenes in the presence of a catalytic amount of Pd(OAc)2, a chiral bidentate pyrox ligand and O2 as terminal oxidant affords the structurally diverse indole-cyclopentene conjugates, e.g., I, bearing two stereocenters in a highly diastereo- and enantio-selective manner. One of the products is converted to a heavily functionalized tetracyclic indolinone derivative The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to alkynylaniline cyclopentene diastereoselective enantioselective palladium pyrox aminopalladation heck cascade, indole cyclopentene stereoselective preparation, asymmetric synthesis, domino reactions, homogeneous catalysis, nucleopalladation, oxidative heck reactions and other aspects.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 17, 2017, Huang, He; Wu, Yang; Zhang, Wen; Feng, Chun; Wang, Bi-Qin; Cai, Wan-Fei; Hu, Ping; Zhao, Ke-Qing; Xiang, Shi-Kai published an article.SDS of cas: 321-28-8 The title of the article was Copper-Catalyzed Regioselective C-H Sulfonyloxylation of Electron-Rich Arenes with p-Toluenesulfonic Acid and Sulfonyloxylation of Aryl(mesityl)iodonium Sulfonates. And the article contained the following:

Copper-catalyzed regioselective C-H sulfonyloxylation of electron-rich arenes with p-toluenesulfonic acid has been developed. Electron-rich benzene derivatives and heteroarenes can undergo this C-H sulfonyloxylation reaction to generate aryl tosylates. Furthermore, sulfonyloxylation of aryl(mesityl)iodonium sulfonates has also been investigated. Both aryl(mesityl)iodonium tosylates and triflates can react smoothly to get aryl sulfonates. The formed aryl sulfonates, e.g., I, can be converted to phenols, as well as used as good partners of cross-coupling reactions. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8

The Article related to toluenesulfonic acid electron rich arene regioselective ch sulfonyloxylation copper, arylmesityliodonium sulfonate electron rich arene regioselective ch sulfonyloxylation, aryl sulfonate regioselective preparation, copper regioselective ch sulfonyloxylation catalyst and other aspects.SDS of cas: 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Zhuo; Jiang, Hang; Zhang, Yanghui published an article in 2021, the title of the article was Pd-catalyzed cross-electrophile Coupling/C-H alkylation reaction enabled by a mediator generated via C(sp3)-H activation.Formula: C8H10O And the article contains the following content:

Pd-catalyzed cascade cross-electrophile coupling and C-H alkylation reaction of 2-iodo-alkoxylarenes with alkyl chlorides were reported. Methoxy and benzyloxy groups, which were ubiquitous functional groups and common protecting groups, were utilized as crucial mediators via primary or secondary C(sp3)-H activation. The reaction provided an innovative and convenient access for the synthesis of alkylated phenol derivatives, which were widely found in bioactive compounds and organic functional materials. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Formula: C8H10O

The Article related to methoxy alkylarene preparation regioselective, haloalkane methoxy aryliodide palladium tandem alkylation oxidative cross coupling, benzyloxy alkylbenzene preparation regioselective, phenyl benzyloxyiodide haloalkane palladium tandem alkylation oxidative cross coupling and other aspects.Formula: C8H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Zhuo; Jiang, Hang; Zhang, Yanghui published an article in 2021, the title of the article was Pd-catalyzed cross-electrophile Coupling/C-H alkylation reaction enabled by a mediator generated via C(sp3)-H activation.Reference of 2-Methoxynaphthalene And the article contains the following content:

Pd-catalyzed cascade cross-electrophile coupling and C-H alkylation reaction of 2-iodo-alkoxylarenes with alkyl chlorides were reported. Methoxy and benzyloxy groups, which were ubiquitous functional groups and common protecting groups, were utilized as crucial mediators via primary or secondary C(sp3)-H activation. The reaction provided an innovative and convenient access for the synthesis of alkylated phenol derivatives, which were widely found in bioactive compounds and organic functional materials. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Reference of 2-Methoxynaphthalene

The Article related to methoxy alkylarene preparation regioselective, haloalkane methoxy aryliodide palladium tandem alkylation oxidative cross coupling, benzyloxy alkylbenzene preparation regioselective, phenyl benzyloxyiodide haloalkane palladium tandem alkylation oxidative cross coupling and other aspects.Reference of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 21, 2001, Peng, Kang-Yung; Chen, Show-An; Fann, Wun-Shain published an article.Recommanded Product: 1-((2-Ethylhexyl)oxy)-4-methoxybenzene The title of the article was Efficient Light Harvesting by Sequential Energy Transfer across Aggregates in Polymers of Finite Conjugational Segments with Short Aliphatic Linkages. And the article contained the following:

A series of light-harvesting polymers (poly-DSBs) of dialkyloxy- or dialkyl-substituted distyrylbenzene ( substituents = methoxy, 2-ethylhexyloxy, and cyclohexyl) with methylene or ethylene spacers were prepared The interactions between lumophores and the role of chem. structure of poly-DSBs on the absorption, emission, and excitation spectra were studied. The proximity of distyrylbenzene lumophores was critical to effective interactions and to the energy-transfer processes. In concentrated solutions and solid films, intermol. aggregates exist resulting from different extents of interactions between lumophores and involve at least three species: loose, compact, and aligned aggregates as observed by photoluminescence and excitation spectroscopy. Sequential energy transfer was directly observed from individual lumophores to the most compact, aligned aggregates via looser intermol. aggregates by time-resolved fluorescence spectroscopy. This process mimics energy transfer in photosynthesis and is highly efficient; fluorescence can be red-shifted drastically by the presence of comparatively few aggregates and light from concentrated solutions and films of poly-DSBs is entirely or almost due to aggregation emission. Although sequential energy-transfer in fully conjugated electro/photoluminescent polymers due to inhomogeneity other than distributed conjugation length has never been directly observed at room temperature, events similar to those observed in poly-DSBs could occur but on a much shorter time scale, i.e., a few picoseconds. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Recommanded Product: 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to alkyl substituted styrylbenzene light harvesting polymer preparation, aggregation conjugated polymer alkyl substituted styrylbenzene lumophore, energy transfer aggregate alkyl substituted styrylbenzene polymer, conjugated polymer alkyl alkoxy substituted styrylbenzene and other aspects.Recommanded Product: 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem