Month: October 2022

《Synthesis, Photophysics and Theoretical Calculation of (E)-2-(benzo[d] thiazol-2-yl)-3-(3-methoxyphenyl)acrylonitrile》 was published in Letters in Organic Chemistry in 2020. These research results belong to Wu, Pei-Chieh; Chen, Chih-Hsien. Recommanded Product: 2398-37-0 The article mentions the following:

A new type of luminogen with aggregation-induced-emission (AIE) behavior was designed and synthesized. The result of single-crystal x-ray structure showed a planar structure in which the dihedral angle between two aromatic rings is < 30o. Also, two different intermol. H bond interactions supported the stability of the crystal structure. After the formation of organic nanoparticles in poor solubility solvent, the emission intensity of the desired product was increased and the enhancement achieved was 14-fold. This new design of luminogen provided further understanding of the AIE mechanism. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Recommanded Product: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Recommanded Product: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Green synthesis and antibacterial activity of chalcogenoesters》 was published in Monatshefte fuer Chemie in 2020. These research results belong to da Silva, Rafael S.; Junior, Guerino B.; Soares, Letiere C.; da Rosa, Fernanda H.; Ravanello, Bruno B.; Dornelles, Luciano; Barboza, Victor dos S.; Vaucher, Rodrigo de A.; Santos, Roberto C. V.; Baldisserotto, Bernardo; Rodrigues, Oscar E. D.. COA of Formula: C12H10S2 The article mentions the following:

A new variation for an eco-friendly methodol. for the synthesis of chalcogenoester RC(O)YAr (R = 4-CH3C6H4, 4-O2NC6H4, 2-ClC6H4, 4-(CH3)3CC6H4; Ar = C6H5, 2-CH3OC6H4, 4-CH3C6H4, 4-ClC6H4; Y = Se, S) in good-to-excellent yields in a short time, with an easy work-up/purification step, and in a greenest methodol., affording the min. generation of solid and liquid waste, in comparison to that described in the literature has been described. Addnl., some selected compounds RC(O)YAr (R = 4-CH3C6H4, Ar = C6H5, Y = Se; R = 4-O2NC6H4, Ar = C6H5, Y = Se; R = Ar = 4-CH3C6H4, Y = Se; R = 4-CH3C6H4, Ar = 4-ClC6H4, Y = S; R = 4-O2NC6H4, Ar = 4-ClC6H4, Y = S) were evaluated as antimicrobial agents, showing moderate activity against a variety of microorganisms including the K. pneumonia, P. aeruginosa and also some selected fish pathogenic bacteria. In the experimental materials used by the author, we found 1,2-Diphenyldisulfane(cas: 882-33-7COA of Formula: C12H10S2)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.The C-O bonds that comprise simple ethers are strong. They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes. COA of Formula: C12H10S2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Synthesis, characterization and antibacterial effect of diarylmethylamine-based imines》 was published in Journal of Molecular Structure in 2020. These research results belong to Onur, Sultan; Kose, Muhammet; Kocer, Ferudun; Tumer, Ferhan. Safety of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:

Firstly, starting from benzoic acid, the diarylmethanone compound (4-methylphenyl)(phenyl)methanone was synthesized. The diarylmethanone (4-methylphenyl)(phenyl)methanone was converted to the corresponding oxime N-[(4-methylphenyl)(phenyl)methylidene]hydroxylamine and then reduced to the diarylmethylamine compd (4-methylphenyl)(phenyl)methanamine. Four different imine compounds2-OH-3-R1-4-R2C6H2CH=NCH(4-CH3C6H5)C6H4(R1 = H, OH, OMe; R2 = H, OH, OMe) were obtained from the condensation of the (4-methylphenyl)(phenyl)methanamine with four different salicylaldehyde 2-OH-3-R1-4-R2C6H2CHO. Antimicrobial activities against Gram (+) and Gram (-) microorganisms (Staphylococcus aureus, Bacillus cereus as the Gram (+); Escherichia coli and Salmonella typhimurium as the Gram (-); and Candida albicans as the fungi) were investigated. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《A Selectfluor-promoted oxidative reaction of disulfides and amines: access to sulfinamides》 was published in Organic & Biomolecular Chemistry in 2020. These research results belong to Mei, Haibo; Liu, Jiang; Pajkert, Romana; Roschenthaler, Gerd-Volker; Han, Jianlin. Formula: C12H10S2 The article mentions the following:

An unprecedented transition-metal-free oxidative reaction of disulfides and amines with Selectfluor as a mild oxidant under aerobic conditions was developed. This reaction was conducted under mild conditions and tolerated a wide range of coupling partners including disulfides and amines, affording the corresponding sulfinamide products in good chem. yields. Furthermore, this reaction could be used in gram-scale synthesis. This reaction enriches the research content of Selectfluor and provides a valuable vista for the convenient synthesis of sulfinamides. After reading the article, we found that the author used 1,2-Diphenyldisulfane(cas: 882-33-7Formula: C12H10S2)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Formula: C12H10S2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Selectfluor-initiated cyanation of disulfides to thiocyanates》 was published in Journal of Chemical Research in 2020. These research results belong to Zhou, Pengpeng; Chen, Chuan; Li, Shubai. HPLC of Formula: 882-33-7 The article mentions the following:

A Selectfluor-initiated cyanation of disulfides to thiocyanates was developed. In this process, Selectfluor was employed as the oxidant and trimethylsilyl cyanide was used as the cyanation reagent. It provides an eco-friendly and simple way to synthesize the thiocyanates. In the experiment, the researchers used 1,2-Diphenyldisulfane(cas: 882-33-7HPLC of Formula: 882-33-7)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.The C-O bonds that comprise simple ethers are strong. They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes. HPLC of Formula: 882-33-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Palladium/N,N’-Disulfonyl Bisimidazoline-Catalyzed Enantioselective Addition of Arylboronic Acids to Cyclic N-Sulfonyl Ketimines》 was written by Li, Meng-Fan; Miao, An-Qi; Zhu, Hong-Yu; Wang, Rong; Hao, Wen-Juan; Tu, Shu-Jiang; Jiang, Bo. HPLC of Formula: 10365-98-7 And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

The combination of Pd(TFA)2 and an N,N’-disulfonyl bisimidazoline ligand shows high catalytic activity and excellent asym. induction in the addition of arylboronic acids to cyclic N-sulfonyl ketimines including benzo[d]isothiazole-1,1-dioxides, benzo[e][1,2,3]oxathiazine-2,2-dioxides, and 1,2,5-thiadiazole-1,1-dioxides, by which three types of chiral quaternary carbon-containing sultams with substantial substitution diversity were synthesized with high yields and excellent enantioselectivities (up to >99% ee). The current catalysis demonstrated a remarkable tolerance to oxygen and thus provided an operationally simple approach for constructing enantioenriched cyclic quaternary stereocenters. The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7HPLC of Formula: 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.HPLC of Formula: 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Miao, Shi-Xing; Wan, Lin-Xi; He, Zhen-Xiang; Zhou, Xian-Li; Li, Xiaohuan; Gao, Feng published their research in Journal of Natural Products in 2021. The article was titled 《Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer’s Disease Drug: Synthesis and Biological Evaluation of N-Aryl Huperzine A Analogues》.SDS of cas: 2398-37-0 The article contains the following contents:

The first systematic direct diversification of a complex natural product by metal-catalyzed N-H functionalization was carried out. A new series of N-(hetero)aryl analogs I (Ar = Ph, 2-naphthyl, 4-methylpyridin-2-yl, etc.) of the natural anti-Alzheimer’s disease drug huperzine A (HPA) was prepared via palladium-catalyzed Buchwald-Hartwig cross-coupling reactions of HPA with various aryl bromides ArBr in good yields. Most of the N-aryl-huperzine A (N-aryl-HPA) analogs showed good acetylcholinesterase (AChE) inhibitory activity in in vitro experiments Three arylated huperzine A analogs I (Ar = 4-FC6H4, 4-methoxy-2,6-dimethylphenyl, 5-methoxypyridin-2-yl) exhibited stronger anti-AChE activity than HPA. The 5-methoxy-2-pyridyl analog I (Ar = 5-methoxypyridin-2-yl) displayed the most potent AChE inhibition activity, with an IC50 value of 1.5μM, which was 7.6-fold more active than HPA. Compound I (Ar = 5-methoxypyridin-2-yl) also exhibited better neuroprotective activity for H2O2-induced damage in SH-SY5Y cells than HPA. Structure-activity relationship anal. suggested that the electron d. of the installed aromatic ring or heteroaromatic ring played a significant role in inducing the AChE inhibition activity. Overall, compound I (Ar = 5-methoxypyridin-2-yl) showed the advantages of easy synthesis, high potency and selectivity, and improved neuroprotection, making it a potential huperzine-type lead compound for Alzheimer’s disease drug development. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0SDS of cas: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.SDS of cas: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sands, Kai N.; Gelfand, Benjamin S.; Back, Thomas G. published their research in Journal of Organic Chemistry in 2021. The article was titled 《One-Pot Synthesis of Aryl Selenonic Acids and Some Unexpected Byproducts》.Electric Literature of C7H7BrO The article contains the following contents:

The synthesis of aryl selenonic acids was achieved from diverse aryl bromides via a one-pot method involving metalation, selenation, and oxidation with hydrogen peroxide followed by ion exchange to afford the pure products in 77-90% yield. An o-hydroxymethyl derivative was found to dehydrate readily, affording the first example of a cyclic selenonic ester, while two minor byproducts were isolated and shown by X-ray crystallog. to be mixed salts of aryl selenonic acids with either the corresponding aryl seleninic or selenious acid. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Electric Literature of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Electric Literature of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Wu; Shu, Xiaomin; Huan, Leitao; Cheng, Buqing; Huo, Haohua published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Enantioselective β-C(sp3)-H arylation of amides via synergistic nickel and photoredox catalysis》.Reference of 1-Bromo-3-methoxybenzene The article contains the following contents:

An enantioselective benzylic β-C(sp3)-H arylation of amides RC(O)CH2CH2Ar (R = Me, phenylaminyl, [3-(trifluoromethyl)phenyl]aminyl, Ph, etc.; Ar = Ph, 4-methoxyphenyl, 3-chlorophenyl, etc.) via synergistic nickel and photoredox catalysis is reported. The C-H bond is activated by a bromine-radical-mediated C-H cleavage. This mild yet straightforward protocol provides arylation products (S)-RC(O)CH2CH(R1)Ar (R1 = 4-(trifluoromethyl)phenyl, 4-cyanophenyl, 3-bromophenyl, 1-benzothiophen-5-yl, etc.) in up to 96% yield and with up to 95% ee. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Reference of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Reference of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Vankar, H. P.; Rana, V. A. published their research in Materials Today: Proceedings in 2021. The article was titled 《Density, viscosity and ultrasonic velocity study: Binary mixtures of 3-bromoanisole and methanol at different temperatures》.COA of Formula: C7H7BrO The article contains the following contents:

The values of d., viscosity and ultrasonic velocity at three different temperatures (303.15, 313.15 and 323.15 K) of the prepared binary mixture solutions with different compositions of 3-bromoanisole (3-BA) and methanol (MeOH) are exptl. determined and presented. Moreover, the excess values of molar volume, viscosity and ultrasonic velocity have been determined These determined excess properties are fitted to the Redlich-Kister equation. Deviations from the linearity are found in the exptl. measured parameters with variation in mixture composition and are interpreted in terms of mol. interaction. Moreover, thermodn. properties are evaluated to understand the dynamic behavior of the system. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0COA of Formula: C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.COA of Formula: C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem