Month: November 2022

Bai, Chaolumen; Chao, Bao; Muschin, Tegshi; Bao, Agula; Baiyin, Menghe; Liu, Dan; Bao, Yong-Sheng published an article in 2021, the title of the article was Regiodivergent CDC reactions of aromatic aldehydes with unactivated arenes controlled by transient directing strategy.Category: ethers-buliding-blocks And the article contains the following content:

The regiodivergent catalytic dehydrogenative cross-coupling reactions at both sp2 and sp3 hybridized carbons of aromatic compounds are particularly challenging. Herein, the finding of transient directing group controlled regiodivergent C(sp3)-C(sp2) and C(sp2)-C(sp2) cross-coupling in the o-Me benzaldehyde frameworks 2-CH3RC6H3CHO (R = H, 6-Me, 4-Br, 4,6-(CH3)2, etc.) is reported. Catalyzed by palladium, using K2S2O8 or [F+] reagents as by-standing oxidants and unactivated arenes R1C6H5 (R1 = H, OEt, Me, Cl, etc.) as substrates/solvents, various benzyl benzaldehydes RC6H3CHO-2-CH2C6H4R1 or Ph benzaldehydes R-2-MeC6H2CHOC6H4R1 were prepared A mechanism study indicated that the regiospecificity is dominated by the [5,6]-fused palladacycle or [6,5]-fused palladacycle intermediates, which are generated from Pd-chelation with specified transient directing groups and further C-H activations. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Category: ethers-buliding-blocks

The Article related to benzylbenzaldehyde preparation regioselective, phenylbenzaldehyde preparation regioselective, arene aromatic aldehyde coupling reaction palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Aldehydes and Derivatives, Including Sulfur Analogs and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 27, 2013, Ye, Yingda; Sanford, Melanie S. published an article.Application of 321-28-8 The title of the article was Mild Copper-Mediated Fluorination of Aryl Stannanes and Aryl Trifluoroborates. And the article contained the following:

This communication describes a mild copper-mediated fluorination of aryl stannanes and aryl trifluoroborates with N-fluoro-2,4,6-trimethylpyridinium triflate. This protocol demonstrates broad substrate scope and functional group tolerance, and does not require the use of any noble metal additives. The reaction is proposed to proceed via an arylcopper(III) fluoride intermediate. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Application of 321-28-8

The Article related to copper catalyst fluorination aryl stannane trifluoroborate, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Application of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On December 6, 2019, He, Jingjing; Yang, Kang; Zhao, Jianhong; Cao, Song published an article.Name: 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was LiHMDS-Promoted Palladium-Catalyzed Sonogashira Cross-Coupling of Aryl Fluorides with Terminal Alkynes. And the article contained the following:

A highly efficient Pd-catalyzed Sonogashira coupling of various aryl fluorides with terminal alkynes in the presence of LiHMDS was developed. Both unreactive electron-rich fluoroarenes and electron-poor fluoroarenes proceeded smoothly and afforded the corresponding internal alkynes in moderate to excellent yields. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Name: 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to aryl fluoride terminal alkyne sonogashira coupling palladium catalyst lhmds, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Name: 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Salamanca, Vanesa; Albeniz, Ana C. published an article in 2021, the title of the article was Faster palladium-catalyzed arylation of simple arenes in the presence of a methylketone: beneficial effect of an a priori interfering solvent in C-H activation.Electric Literature of 91-16-7 And the article contains the following content:

The arylation of arenes with no directing groups (non-chelate assisted) was carried out using the cooperating ligand [2,2′-bipyridin]-6(1H)-one (bipy-6-OH), the use of a moderately coordinating solvent allows a decrease of the amount of arene used. Moreover, for the least coordinating arenes, the co-solvent produced a significant accelerating effect by altering the concentration and relative stability of relevant metal species in the catalytic cycle as well as the catalyst resting state. t-Bu Me ketone (pinacolone) was one of the most effective co-solvents: Even if the ketone C-H bond cleaves easily, the final products were determined by the reductive elimination step (the product-forming step) so the target biaryl products were selectively observed The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Electric Literature of 91-16-7

The Article related to arene haloarene palladium catalyst regioselective arylation, biaryl preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Electric Literature of 91-16-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 30, 2021, Rawat, Vishal Kumar; Higashida, Kosuke; Sawamura, Masaya published an article.Computed Properties of 93-04-9 The title of the article was Nickel-Catalyzed Homocoupling of Aryl Ethers with Magnesium Anthracene Reductant. And the article contained the following:

Nickel-catalyzed reductive homocoupling of aryl ethers has been achieved with Mg(anthracene)(thf)3 as a readily available low-cost reductant. DFT calculations provided a rationale for the specific efficiency of the diorganomagnesium-type two-electron reducing agent. The calculations show that the dianionic anthracene-9,10-diyl ligand reduces the two aryl ether substrates, resulting in the homocoupling reaction through supply of electrons to the Ni-Mg bimetallic system to form organomagnesium nickel(0)-ate complexes, which cause two sequential C-O bond cleavage reactions. The calculations also showed cooperative actions of Lewis acidic magnesium atoms and electron-rich nickel atoms in the C-O cleavage reactions. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9

The Article related to aryl ether reductive homocoupling nickel catalyst magnesium anthracene reductant, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Computed Properties of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Feng, Boya; Zhang, Guodong; Feng, Xu; Chen, Yu published an article in 2022, the title of the article was Palladium-catalyzed decarbonylative methylation of aryl carboxylic acids.Quality Control of 2-Methylanisole And the article contains the following content:

Described herein is a palladium-catalyzed decarbonylative methylation of aryl carboxylic acids using trimethylboroxine (TMB) as the methylating reagent. The Pd(OAc)2/XantPhos system is compatible with a wide range of carboxylic acids and derivatives including aroyl chloride/fluoride. The successful methylation of bioactive mols. and examples of orthogonal cross-couplings demonstrate the practicality of this method. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Quality Control of 2-Methylanisole

The Article related to aryl carboxylic acid decarbonylative methylation palladium acetate xantphos catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Quality Control of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 21, 2020, Cao, Dawei; Chen, Zhangpei; Lv, Leiyang; Zeng, Huiying; Peng, Yong; Li, Chao-Jun published an article.Product Details of 578-58-5 The title of the article was Light-Driven Metal-Free Direct Deoxygenation of Alcohols under Mild Conditions. And the article contained the following:

An efficient metal-free strategy that enabled direct deoxygenation of alcs. to arenes such as RCH2R1 [R = Ph, 2-MeOC6H4, 2-naphthyl, etc.; R1 = H, Me, Ph, etc.] had been developed for the first time, with hydrazine as the reductant induced by light. The features of this protocol were mild reaction conditions, excellent functional group tolerance, and abundant and easily available starting materials, rendering selective deoxygenation of a variety of 1° and 2° alcs., vicinal diols, and β-1 and even β-O-4 models of natural wood lignin. This strategy was also highlighted by its “traceless” and non-toxic byproducts N2 and H2, as readily escapable gases. Mechanistic studies demonstrated di-Me sulfide being a key intermediate in this transformation. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Product Details of 578-58-5

The Article related to arene preparation photochem, alc deoxygenation, catalysis, chemistry, organic chemistry, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Product Details of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Tang, Lin; Wu, Chaoting; Hu, Qiyan; Li, Qian; Zhang, Wu published an article in 2018, the title of the article was Cross-coupling reactions using porous multipod Cu2O microcrystals as recoverable catalyst in aqueous media.Related Products of 157869-15-3 And the article contains the following content:

Porous multipod Cu2O microcrystals were found to be an efficient, highly recyclable and eco-friendly catalyst for the cross-coupling reactions of aryl halides and terminal alkynes with high yields in aqueous media. Noteworthy, the Cu2O catalyst can be reused for several times without significant decrease in catalytic activity. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to aryl halide alkyne terminal copper sonogashira coupling catalyst, alkyne aryl preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Related Products of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 21, 2018, Ho, Yee Ann; Leiendecker, Matthias; Liu, Xiangqian; Wang, Chengming; Alandini, Nurtalya; Rueping, Magnus published an article.Product Details of 321-28-8 The title of the article was Nickel-Catalyzed Csp2-Csp3 Bond Formation via C-F Bond Activation. And the article contained the following:

A nickel-catalyzed cross coupling of aryl fluorides via C-F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to alkylarene preparation, aryl fluoride alkyl grignard reagent cross coupling nickel catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Product Details of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yin, Biao; Fu, Manlin; Wang, Lei; Liu, Jiang; Zhu, Qing published an article in 2020, the title of the article was Dual ligand-promoted palladium-catalyzed nondirected C-H alkenylation of aryl ethers.HPLC of Formula: 578-58-5 And the article contains the following content:

Herein, a novel strategy for nondirected C-H alkenylation of alkyl aryl ethers (anisole, phenetole, Pr Ph ether, Bu Ph ether and benzyl Ph ether), cyclic aryl ethers (1,4-benzodioxane, 2,3-dihydrobenzofuran, dibenzofuran), and di-Ph oxide promoted by a dual ligand catalyst was demonstrated. This catalytic system readily achieved the highly efficient alkenylation of aryl ethers. Moreover, the proposed methodol. was successfully employed for the late-stage modification of complex drugs containing the aryl ether motif. Interestingly, the compounds developed herein displayed fluorescent properties, which would facilitate their biol. applications. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).HPLC of Formula: 578-58-5

The Article related to aryl alkene preparation diastereoselective, alkene aryl ether alkenylation palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.HPLC of Formula: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem