Month: November 2022

On June 30, 2017, Sinai, Adam; Meszaros, Adam; Balogh, Adam; Zwillinger, Marton; Novak, Zoltan published an article.Product Details of 157869-15-3 The title of the article was Hexafluorosilicic Acid as a Novel Reagent for the Desilylation of Silylacetylenes: Application in Sequential Sonogashira Coupling and Click Reaction. And the article contained the following:

Hexafluorosilicic acid was utilized as a novel, cheap, readily available, and environmentally benign alternative reagent for the desilylation of 1-trimethylsilylacetylenes. The applicability of the aqueous solution of the hexafluorosilicic acid was demonstrated in the sequential coupling of aryl halides and ethynyltrimethylsilane to afford internal acetylenes, benzofurans, and triazoles in one-pot Sonogashira-Sonogashira and Sonogashira-CuAAC reactions. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Product Details of 157869-15-3

The Article related to arylalkyne preparation, aryl iodide silylacetylene sequential sonogashira coupling click chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Product Details of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 31, 2013, Liu, Zong-ying; Wang, Yue-ming; Han, Yan-xing; Liu, Ling; Jin, Jie; Yi, Hong; Li, Zhuo-rong; Jiang, Jian-dong; Boykin, David W. published an article.Recommanded Product: 1-Fluoro-2-methoxybenzene The title of the article was Synthesis and antitumor activity of novel 3,4-diaryl squaric acid analogs. And the article contained the following:

A series of novel 3,4-diaryl squaric acid analogs 4a-r related to combretastatin A-4 (CA4) using squaric acid as the cis-restricted linker were prepared and studied for their anticancer activity against selected human cancer cell lines. New compounds 4g, 4k, 4m, 4n, 4p, 4q and 4r exhibit strong activities against human leukemia cells with IC50 values of ≤20 nM and compounds 4k, 4n, 4p, 4q and 4r showed potent activities against a panel of human tumor cell lines. Compounds 4n and 4p arrest tumor cell cycle in G2-M phase. Computational modeling anal. suggests that the binding mechanism of compound 4n to the colchicine binding site on the microtubules is similar to that of CA4. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Recommanded Product: 1-Fluoro-2-methoxybenzene

The Article related to antitumor diaryl squaric acid analog, 3,4-diaryl squaric acid analogs, anticancer, cytotoxic agents, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Recommanded Product: 1-Fluoro-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 31, 2021, Higginson, Bradley; Sanjose-Orduna, Jesus; Gu, Yiting; Martin, Ruben published an article.Formula: C8H10O2 The title of the article was Nickel-Catalyzed Photodehalogenation of Aryl Bromides. And the article contained the following:

Herein, Ni-catalyzed photodehalogenation of aryl bromides under visible-light irradiation that utilizes THF as hydrogen source were described. The protocol obviated the need for exogenous amine reductants or photocatalysts and was characterized by its simplicity and broad scope, including challenging substrate combinations. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Formula: C8H10O2

The Article related to aryl bromide thf nickel catalyst photodehalogenation, arene preparation, deuterated arene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Formula: C8H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wu, Yaxing; Ding, Hongliang; Zhao, Ming; Ni, Zhong-Hai; Cao, Jing-Pei published an article in 2020, the title of the article was Electrochemical and direct C-H methylthiolation of electron-rich aromatics.Synthetic Route of 93-04-9 And the article contains the following content:

The electrochem.-induced C-H methylthiolation of electron-rich aromatics for the synthesis of thiomethylated aromatics ArSR [R = Me, Et, n-Pr; Ar = 4-MeOC6H4, 4-MeNHC6H4, 2-MeO-1-naphthyl, etc.] was accomplished via a three component cross-coupling strategy. Potassium thiocyanate (KSCN) as both the supporting electrolyte and sulfur source and methanol as the methylation reagent were used. This protocol was versatile for various (hetero)aromatic compounds such as aniline, anisole and indole. The reaction proceeded under mild conditions without any metal catalyst, exogenous oxidant and highly toxic sulfur reagent. Importantly, such an electrochem.-induced methylthiolated reaction could be easily scaled up with good efficiency. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Synthetic Route of 93-04-9

The Article related to thiomethylated aromatic compound preparation, electron rich aromatic compound electrochem methylthiolation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Synthetic Route of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 7, 2020, Panigrahi, Adyasha; Whitaker, Daniel; Vitorica-Yrezabal, Inigo J.; Larrosa, Igor published an article.Electric Literature of 321-28-8 The title of the article was Ag/Pd Cocatalyzed Direct Arylation of Fluoroarene Derivatives with Aryl Bromides. And the article contained the following:

Diverse C-H functionalizations catalyzed by Pd employ Ag(I) salts added as halide abstractors or oxidants. Recent reports have shown that Ag can also perform the crucial C-H activation step in several of these functionalizations. However, all of these processes are limited by the wasteful requirement for (super)stoichiometric Ag(I) salts. Herein, we report the development of a Ag/Pd cocatalyzed direct arylation of (fluoroarene) chromium tricarbonyl complexes with bromoarenes. The small organic salt, NMe4OC(CF3)3, added as a halide abstractor, enables the use of a catalytic amount of Ag, reversing the rapid precipitation of AgBr. We have shown through H/D scrambling and kinetic studies that a (PR3)Ag-alkoxide is responsible for C-H activation, a departure from previous studies with Ag carboxylates. Furthermore, the construction of biaryls directly from the simple arene is achieved via a one-pot chromium tricarbonyl complexation/C-H arylation/decomplexation sequence using (pyrene)Cr(CO)3 as a Cr(CO)3 donor. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Electric Literature of 321-28-8

The Article related to biaryl preparation, fluoroarene chromium tricarbonyl complex bromoarene arylation silver palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Electric Literature of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 3, 2022, Caldarelli, Marina; Laze, Loris; Piazza, Lavinia; Caputo, Giulia; De Amici, Marco; Papeo, Gianluca published an article.Computed Properties of 93-04-9 The title of the article was Use of acridinium-based photocatalyst in the Giese-type coupling of arylboronic acids with electron poor olefins. And the article contained the following:

The development of a visible light-mediated Giese-type reaction using arylboronic acids as aryl radical source was described. The synthetic protocol capitalizes on the employment of environmentally benign metal-free catalyst to forge Csp2-Csp3 bonds. Applications of the methodol. to the synthesis of aminoesters and the anti-inflammatory drug nabumetone, either in batch or in flow, was also reported. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Computed Properties of 93-04-9

The Article related to alkene arylboronic acid mesityl acridinium photocatalyst giese coupling, aryl alkane preparation green chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Computed Properties of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ishida, Naoki; Shinoya, Hiroki; Kamino, Yuka; Kawasaki, Tairin; Murakami, Masahiro published an article in 2022, the title of the article was Dehydrogenative Three-component Coupling of CO with Methylarenes Forming Dibenzyl Ketones.Recommanded Product: 2-Methylanisole And the article contains the following content:

NUM Herein reported is a photoinduced dehydrogenative three-component coupling reaction of carbon monoxide with two mols. of methylarenes fArCH3 (Ar = Ph, 2-naphthyl, 2-thiophenyl, etc.) forming dibenzyl ketones ArCH2C(O)CH2Ar. A gaseous dihydrogen mol. evolves as the byproduct, and neither oxidants nor hydrogen acceptors are required. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 2-Methylanisole

The Article related to dibenzyl ketone preparation photochem, methylarene carbon monoxide dehydrogenative three component coupling iridium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Recommanded Product: 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 15, 2022, Zhang, Wenxuan; Sun, Jiaying; Lian, Zhendong; Song, Ran; Yang, Daoshan; Lv, Jian published an article.Synthetic Route of 578-58-5 The title of the article was Enantioselective Friedel-Crafts Reaction of 2-Alkynyphenols with Aromatic Ethers by Chiral Bronsted Acid Catalysis. And the article contained the following:

Herein, authors report chiral strong Bronsted acid-catalyzed enantioselective Friedel-Crafts reaction of 2-alkynyphenols with aromatic ethers. The reaction affords the corresponding axially chiral styrenes in up to 91% yield and 97% ee. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Synthetic Route of 578-58-5

The Article related to axially chiral styrene preparation enantioselective strong bronsted acid catalyst, alkynyphenol aromatic ether friedel crafts, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Synthetic Route of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 15, 2022, Zhang, Wenxuan; Sun, Jiaying; Lian, Zhendong; Song, Ran; Yang, Daoshan; Lv, Jian published an article.Synthetic Route of 150-78-7 The title of the article was Enantioselective Friedel-Crafts Reaction of 2-Alkynyphenols with Aromatic Ethers by Chiral Bronsted Acid Catalysis. And the article contained the following:

Herein, authors report chiral strong Bronsted acid-catalyzed enantioselective Friedel-Crafts reaction of 2-alkynyphenols with aromatic ethers. The reaction affords the corresponding axially chiral styrenes in up to 91% yield and 97% ee. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Synthetic Route of 150-78-7

The Article related to axially chiral styrene preparation enantioselective strong bronsted acid catalyst, alkynyphenol aromatic ether friedel crafts, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Synthetic Route of 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lamola, Jairus L.; Moshapo, Paseka T.; Holzapfel, Cedric W.; Maumela, Munaka Christopher published an article in 2021, the title of the article was Evaluation of P-bridged biaryl phosphine ligands in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions.Category: ethers-buliding-blocks And the article contains the following content:

A family of biaryl phosphacyclic ligands derived from phobane and phosphatrioxa-adamantane frameworks was described. The rigid biaryl phosphacycles were efficient for synthesis of biaryls ArAr1 [Ar = 3-MeC6H4, 2-naphthyl, 2-thienyl, etc.; Ar1 = Ph, 2-MeC6H4, 2,6-di-MeC6H3] via palladium-catalyzed Suzuki-Miyaura cross-coupling of aryl bromides/chlorides with phenylboronic acids. In particular, coupling reactions of the challenging sterically hindered and heterocyclic substrates were viable at room temperature The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Category: ethers-buliding-blocks

The Article related to phosphacyclic ligand preparation, biaryl preparation, aryl halide phenylboronic acid suzuki miyaura coupling palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem