Month: November 2022

On August 31, 2021, Bao, Can-Can; Luo, Yan-Long; Du, Hui-Zhen; Guan, Bing-Tao published an article.SDS of cas: 578-58-5 The title of the article was Benzylic aroylation of toluenes with unactivated tertiary benzamides promoted by directed ortho-lithiation. And the article contained the following:

The deprotonative functionalization of toluenes, for their weak acidity, generally needed strong bases, thus led to the requirement of harsh conditions and the generation of byproducts. Direct nucleophilic acyl substitution reaction of amides with organometallic reagents could provide an ideal solution for ketone synthesis. However, the inert amides and highly reactive organometallic reagents brought great challenges for an efficient and selective synthetic approach. Herein, an lithium diisopropylamide (LDA)-promoted benzylic aroylation of toluenes with unactivated tertiary benzamides, providing a direct and efficient synthesis of various aryl benzyl ketones ArC(O)CH2Ar1 [Ar = Ph, 3,4-di-MeOC6H3, 2-naphthyl, etc.; Ar1 = Ph, 4-MeOC6H4, 3,5-di-MeC6H3, etc.] was reported. This process featured a kinetic deprotonative functionalization of toluenes with a readily available base LDA. Mechanism studies revealed that the directed ortho-lithiation of the tertiary benzamide with LDA promoted the benzylic kinetic deprotonation of toluene and triggered the nucleophilic acyl substitution reaction with the amide. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).SDS of cas: 578-58-5

The Article related to aryl arylethanone preparation, toluene tertiary arylamide benzylic aroylation ortho lithiation catalyst lda, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.SDS of cas: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 16, 2016, Chen, Tao; Li, Yi-Fan; An, Yang; Zhang, Fu-Min published an article.Synthetic Route of 321-28-8 The title of the article was Iron-Catalyzed α-Arylation of Deoxybenzoins with Arenes through an Oxidative Dehydrogenative Approach. And the article contained the following:

A novel α-arylation of deoxybenzoins with non-prefunctionalized arenes is developed through an iron-catalyzed oxidative dehydrogenative approach. The reaction shows broad substrate scope and functional group tolerance and thus provides efficient access to synthetically useful 1,2,2-triarylethanones. A reasonable mechanism is also proposed. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Synthetic Route of 321-28-8

The Article related to deoxybenzoin arene iron regioselective oxidative arylation catalyst, triaryl ethanone preparation green chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Synthetic Route of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 1, 2021, Li, Xue; Bai, Fang; Liu, Chaogan; Ma, Xiaowei; Gu, Chengzhi; Dai, Bin published an article.Safety of 2-Methylanisole The title of the article was Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls. And the article contained the following:

An efficient electrochem. method for benzylic C(sp3)-H bond oxidation has been developed. A variety of methylarenes, e.g., p-chlorotoluene, methylheteroarenes, e.g., 6-methylquinoline and benzylic (hetero)methylenes, e.g., p-ethyltoluene could be converted into the desired aryl aldehydes, e.g., 4-chlorobenzaldehyde/e.g., quinoline-6-carbaldehyde and aryl ketones, e.g., 1-(p-tolyl)ethan-1-one in moderate to excellent yields in an undivided cell, using O2 as the oxygen source and lutidinium perchlorate as an electrolyte. On the basis of cyclic voltammetry studies, 18O labeling experiments, and radical trapping experiments, a possible single-electron transfer mechanism has been proposed for the electrooxidation reaction. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Safety of 2-Methylanisole

The Article related to aldehyde preparation chemoselective, alkylarene selective electrochem oxygenation, ketone preparation chemoselective, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Safety of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 7, 2021, Bhattacharya, Aditya; mani Shukla, Pushpendra; Maji, Biswajit published an article.Recommanded Product: 93-04-9 The title of the article was “Haliranium Ion”-Induced Intermolecular Friedel-Crafts Alkylation in HFIP: Synthesis of β,β-Diaryl α-Halo carbonyl Compounds. And the article contained the following:

Herein, a highly regio- and diastereoselective haliranium ion-induced intermol. Friedel-Crafts reaction of α,β-unsaturated carbonyl compounds in HFIP is reported. The operationally simple and mild method affords the synthetically useful β,β-diarylated α-halo carbonyl compounds in good yields after a very short reaction time. As an application, a few examples of β,β-diarylated olefins are prepared in excellent yields. Based on the exptl. results and a qual. study of 1D-NMR-experiments, a plausible reaction mechanism is proposed. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 93-04-9

The Article related to halo carbonyl compound preparation regioselective stereoselective, chalcone ester intermol friedel crafts reaction haliranium ion hexafluoropropanol, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Recommanded Product: 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xu, Bo; Liu, Wei; Kuang, Chunxiang published an article in 2014, the title of the article was Palladium-Catalyzed C-H Acylation of Arenes Using Thioethers as Directing Groups.SDS of cas: 53136-21-3 And the article contains the following content:

A highly efficient protocol for regioselective synthesis of diaryl ketones by palladium-catalyzed direct acylation of arenes using thioethers as directing groups is reported. The possible pathway of direct acylation between thioethers and α-oxocarboxylic acids is discussed. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).SDS of cas: 53136-21-3

The Article related to diaryl ketone preparation regioselective acylation arene thioether directing group, palladium catalyzed carbon hydrogen acylation thioether alpha oxocarboxylic acid, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.SDS of cas: 53136-21-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 17, 2020, See, Yi Yang; Sanford, Melanie S. published an article.Quality Control of 2-Methylanisole The title of the article was C-H Amination of Arenes with Hydroxylamine. And the article contained the following:

This Letter describes the development of a TiIII-mediated reaction for the C-H amination of arenes with hydroxylamine. This reaction is applied to a variety of electron-rich (hetero)arene substrates, including a series of natural products and pharmaceuticals. It offers the advantages of mild conditions (room temperature), fast reaction rates (<30 min), compatibility with ambient moisture and air, scalability, and the use of inexpensive com. reagents. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Quality Control of 2-Methylanisole

The Article related to arene hydroxylamine titanium amination, aniline preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Quality Control of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 8, 2021, Wang, Tao; Hoffmann, Marvin; Dreuw, Andreas; Hasagic, Edina; Hu, Chao; Stein, Philipp M.; Witzel, Sina; Shi, Hongwei; Yang, Yangyang; Rudolph, Matthias; Stuck, Fabian; Rominger, Frank; Kerscher, Marion; Comba, Peter; Hashmi, A. Stephen K. published an article.Application In Synthesis of 2-Methylanisole The title of the article was A Metal-Free Direct Arene C-H Amination. And the article contained the following:

Here, a metal-free arene e.g., mesitylene C-H amination using hydroxylamine derivatives 4-(CH3)C6H5S(O)2ON(R)R1 (R = H, Me; R1 = Me, Boc, Bn, etc.) under benign conditions was reported. A charge transfer interaction between the aminating reagents and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven exptl. In addition, this was rationalized by a theor. study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen mol. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole

The Article related to aryl amine preparation chemoselective, arene hydroxylamine amination, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Application In Synthesis of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 8, 2021, Wang, Tao; Hoffmann, Marvin; Dreuw, Andreas; Hasagic, Edina; Hu, Chao; Stein, Philipp M.; Witzel, Sina; Shi, Hongwei; Yang, Yangyang; Rudolph, Matthias; Stuck, Fabian; Rominger, Frank; Kerscher, Marion; Comba, Peter; Hashmi, A. Stephen K. published an article.Formula: C11H10O The title of the article was A Metal-Free Direct Arene C-H Amination. And the article contained the following:

Here, a metal-free arene e.g., mesitylene C-H amination using hydroxylamine derivatives 4-(CH3)C6H5S(O)2ON(R)R1 (R = H, Me; R1 = Me, Boc, Bn, etc.) under benign conditions was reported. A charge transfer interaction between the aminating reagents and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven exptl. In addition, this was rationalized by a theor. study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen mol. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Formula: C11H10O

The Article related to aryl amine preparation chemoselective, arene hydroxylamine amination, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Formula: C11H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 16, 2017, Gao, Chunji; Zhang, Chengcheng; Li, Guoqiang; Hu, Xiaoming; Cui, Dunzhu published a patent.Name: Benzyl(4-bromophenyl)sulfane The title of the patent was Preparation of aromatic amine compound and their application as light-emitting devices. And the patent contained the following:

The invention is related to the preparation of aromatic amine compound I and their application as light-emitting devices. The invention provides an aromatic amine compound I, wherein R1-R4 are independent H, halo, cyano, C1-C30 alkyl, C6-C50 aryl, C7-C50 arylalkyl, C7-50 aryl alkoxy, C7-50 arylalkyl-thiol, or C5-50 heteroaryl; and Ar1 and Ar2 are independently selected from C6-50 arylidene; are claimed. Compound I was prepared by multi-step procedure (procedure given). The inventive aromatic amine compound(current efficiency reaching 6.7 cd/A under elec. c.d. of 20mA/cm2, and service life reaching 6800h) can be used for preparing organic light-emitting devices. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Name: Benzyl(4-bromophenyl)sulfane

The Article related to preparation aromatic amine compound application light emitting devices, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Name: Benzyl(4-bromophenyl)sulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On December 9, 2015, Gao, Chunji; Zhang, Chengcheng; Li, Guoqiang; Hu, Xiaoming; Cui, Dunzhu published a patent.Formula: C13H11BrS The title of the patent was Preparation of aromatic amine compound and their application as light-emitting devices. And the patent contained the following:

The invention is related to the preparation of aromatic amine compound I and their application as light-emitting devices. The invention provides an aromatic amine compound I, wherein R1-R4 are independent H, halo, cyano, C1-C30 alkyl, C6-C50 aryl, C7-C50 arylalkyl, C7-50 aryl alkoxy, C7-50 arylalkyl-thiol, or C5-50 heteroaryl; and Ar1 and Ar2 are independently selected from C6-50 arylidene; are claimed. Compound I was prepared by multi-step procedure (procedure given). The inventive aromatic amine compound(current efficiency reaching 6.7 cd/A under elec. c.d. of 20mA/cm2, and service life reaching 6800h) can be used for preparing organic light-emitting devices. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Formula: C13H11BrS

The Article related to preparation aromatic amine compound application light emitting devices, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Formula: C13H11BrS

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem