Month: November 2022

Pan, Wenjing; Li, Chenchen; Zhu, Haoyin; Li, Fangfang; Li, Tao; Zhao, Wanxiang published an article in 2021, the title of the article was A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK.Safety of 2-Methoxynaphthalene And the article contains the following content:

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C6H5, 3-FC6H4, 2-naphthyl, etc.), R1OCH2Ph (R1 = C6H5, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R2OCH2CH=CH2 (R2 = C6H5, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh2 and tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene

The Article related to phenol preparation, aryl methyl ether demethylation, benzyl ether preparation debenzylation, allyl ether preparation deallylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Safety of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pan, Wenjing; Li, Chenchen; Zhu, Haoyin; Li, Fangfang; Li, Tao; Zhao, Wanxiang published an article in 2021, the title of the article was A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2 and tBuOK.Recommanded Product: 1,4-Dimethoxybenzene And the article contains the following content:

A general method for the demethylation, debenzylation, and deallylation of aryl ethers ROMe (R = C6H5, 3-FC6H4, 2-naphthyl, etc.), R1OCH2Ph (R1 = C6H5, 5,6,7,8-tetrahydronaphthalen-2-yl, 2-naphthyl, etc.) and R2OCH2CH=CH2 (R2 = C6H5, 2,3-dimethylphenyl, 1-naphthyl, etc.) using HPPh2 and tBuOK is reported. The reaction features mild and metal-free reaction conditions, broad substrate scope, good functional group compatibility, and high chem. selectivity towards aryl ethers over aliphatic structures. Notably, this approach is competent to selectively deprotect the allyl or benzyl group, making it a general and practical method in organic synthesis. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Recommanded Product: 1,4-Dimethoxybenzene

The Article related to phenol preparation, aryl methyl ether demethylation, benzyl ether preparation debenzylation, allyl ether preparation deallylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Recommanded Product: 1,4-Dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 16, 2014, Li, Yiming; Pu, Jiahua; Jiang, Xuefeng published an article.Recommanded Product: Benzyl(4-bromophenyl)sulfane The title of the article was A Highly Efficient Cu-Catalyzed S-Transfer Reaction: From Amine to Sulfide. And the article contained the following:

A highly efficient Cu-catalyzed dual C-S bonds formation reaction, proceeding in alc. and water under air, is reported, in which inodorous stable Na2S2O3 is used as a sulfurating reagent. This powerful strategy provides a practical and efficient approach to construct thioethers, using readily available aromatic amines and alkyl halides as starting materials. Sensitive and synthetic useful functional groups could be tolerated. Furthermore, pharmaceuticals, glucose, an amino acid, and a chiral ligand are successfully furnished by this late-stage sulfuration strategy. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Recommanded Product: Benzyl(4-bromophenyl)sulfane

The Article related to thioether preparation dual carbon sulfur bond formation copper catalyst, aromatic amine alkyl halide sulfuration sodium thiosulfate sulfurating reagent, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Recommanded Product: Benzyl(4-bromophenyl)sulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 30, 1996, Mutti, S.; Daubie, C.; Decalogne, F.; Fournier, R.; Montuori, O.; Rossi, P. published an article.Safety of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the article was A convenient synthesis of (S)-(+)-2-(2-methoxyphenyl)propanoic acid. And the article contained the following:

A short, convenient and large scale synthesis of (S)-(+)-2-(2-methoxyphenyl)propanoic acid, involving a resolution of the corresponding racemic acid with quinine, is reported. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Safety of (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to propanoic acid methoxyphenyl preparation, methoxyphenylpropanoic acid preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Safety of (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 31, 2022, Kirihara, Masayuki; Sakamoto, Yugo; Yamahara, Sho; Kitajima, Atsuhito; Kugisaki, Naoki; Kimura, Yoshikazu published an article.Recommanded Product: 2-Methylanisole The title of the article was Aerobic Photooxidation of Toluene Derivatives into Carboxylic Acids with Bromine-Water under Catalyst-Free Conditions. And the article contained the following:

The photoirradiation of toluene derivatives with two equivalent of bromine in benzotrifluoride-water provided a satisfactory yield of the corresponding benzoic acid derivatives Either a fluorescent lamp, blue LED (454 nm), or UV LED (385 nm) was used for the photoreaction. The reaction pathway might proceed through the dibromination of benzylic carbon, generation of the benzylic radical via oxidative C-H abstraction, formation of benzoyl bromide, and hydrolysis of carboxylic acid. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 2-Methylanisole

The Article related to benzoic acid preparation, toluene aerobic photooxidation bromine water catalyst free, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Recommanded Product: 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 30, 2021, Wang, Chang-Cheng; Zhang, Guo-Xiang; Zuo, Zhi-Wei; Zeng, Rong; Zhai, Dan-Dan; Liu, Feng; Shi, Zhang-Jie published an article.Safety of 2-Methylanisole The title of the article was Photo-induced deep aerobic oxidation of alkyl aromatics. And the article contained the following:

In this report, e.g., photo-induced deep aerobic oxidation of (poly)alkyl benzene toluene to benzene (poly)carboxylic acids e.g., benzoic acid was developed. CeCl3 was proved to be an efficient HAT (hydrogen atom transfer) catalyst in the presence of alc. as both hydrogen and electron shuttle. Dioxygen (O2) was found as a sole terminal oxidant. In most cases, pure products were easily isolated by simple filtration, implying large-scale implementation advantages. The reaction provides an ideal protocol to produce valuable fine chems. from naturally abundant petroleum feedstocks. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Safety of 2-Methylanisole

The Article related to benzene polycarboxylic acid preparation green chem, polyalkyl benzene photo aerobic oxidation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Safety of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 29, 1992, Senanayake, Chris H.; Bill, Timothy J.; Larsen, Robert D.; Leazer, John; Reider, Paul J. published an article.Name: (S)-2-(2-Methoxyphenyl)propanoic acid The title of the article was Rabbit liver esterase-mediated enantioselective synthesis of 2-arylpropanoic acids. And the article contained the following:

A novel enzymic resolution of o-substituted 2-arylpropanoic acids I (R = H, iodo, Me, OMe) using rabbit liver esterase is described. The (R)-enantiomer is obtained by enzymic hydrolysis of the Et ester whereas the (S)-enantiomer is obtained by enzyme mediated enantioselective transesterification of allyl propionates to their corresponding Me esters. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Name: (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to arylpropanoic acid resolution enzymic, arylpropionate allyl transesterification esterase mediated, hydrolysis arylpropionate esterase mediated, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Name: (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On January 31, 1992, Fadel, Antoine published an article.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the article was Optically active arylpropionic acids from the stereoselective alkylation of chiral imide enolates. And the article contained the following:

The chiral imides (3-arylacetyl-4-isopropyl/benzyl-2-oxazolidinones I (R = Q, R1 = H, R3 = CHMe2, CH2 Ph), II (R = Q, R1 = H, R2 = 4-CHEtMe, 2,3-4-MeO, R3 = CHMe2), and III (R = Q, R1 = H, R3 = CHMe2) were alkylated via their imide enolates with Me iodide; subsequent removal of the chiral auxiliary provided readily, with high stereoselectivity, the (S)-2-arylpropionic acids I, II, and III (R = OH), in good yield. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to arylacetyloxazolidinone preparation stereoselective alkylation, stereoselective methylation arylacetyloxazolidinone, arylpropionic acid optically active, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Application In Synthesis of (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xu, Ren-Rui; Wen, Dan; Qi, Xinxin; Wu, Xiao-Feng published an article in 2022, the title of the article was Palladium-catalyzed cascade Heck-type cyclization and reductive aminocarbonylation for the synthesis of functionalized amides.Recommanded Product: 2-Methoxynaphthalene And the article contains the following content:

A palladium-catalyzed Heck/carbonylative cyclization process was explored for the synthesis of functionalized amides. By using nitroarenes as readily accessible nitrogen sources, a variety of amide products, e.g., I (Ar = 4-MeC6H4, 2-ClC6H4, 1-naphthyl, 2-thienyl, 8-quinolinyl, etc.), was obtained from the corresponding o-iodoaryl alkenes, e.g., II, in moderate to excellent yields with good functional group compatibility. Furthermore, a late-stage modification of a natural mol. was also achieved by this protocol. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to amide benzopyran benzofuran preparation, alkenyl iodobenzene tandem heck cyclization aminocarbonylation nitroarene palladium catalyst, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, Hui; Chen, Xinyu; Wang, Pei-Long; Shi, Meng-Meng; Shang, Ling-Long; Guo, Heng-Yi; Li, Hongji; Li, Pinhua published an article in 2022, the title of the article was Electrochemical benzylic C-H arylation of xanthenes and thioxanthenes without a catalyst and oxidant.Reference of 2-Methylanisole And the article contains the following content:

A catalyst-free and oxidant-free C-H arylation of xanthenes and thioxanthenes I (R1 = H, Me, OH, Cl, etc.; R2 = H, OMe; R3R4 = -CH=CH-CH=CH-; X = O, S) using electrochem. has been developed, which affords a number of cross-coupling products II (R5 = 4-methoxyphenyl, 4-methoxy-3-methylphenyl, 4-methoxy-3,5-dimethylphenyl, 2H-1,3-benzodioxol-5-yl, etc.) in moderate to good yields. This method is atom- and step-economical as it uses cheap and easily available arenes and heteroarenes as partners directly and the C(sp2)-H/C(sp3)-H type cross-coupling reaction. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Reference of 2-Methylanisole

The Article related to aryl xanthene preparation, xanthene arene electrochem arylation reaction, arylthioxanthene preparation, arene thioxanthene electrochem arylation reaction, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Reference of 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem