Month: November 2022

Anodic Oxidation of Iodobenzene and Iodobenzoic Acids in Acetic Acid Environment – Electrochemical Investigation and Density Functional Theory Study was written by Bystron, Tomas;Devadas, Balamurugan;Bouzek, Karel;Svoboda, Jan;Kolarikova, Viola;Kvicala, Jaroslav. And the article was included in ChemElectroChem in 2021.Name: 2-Methoxyethylamine The following contents are mentioned in the article:

Kinetic and mechanistic aspects of an anodic oxidation of iodobenzene and its selected derivatives leading to the corresponding iodosyl compounds, were investigated in anhydrous acidic acetic acid environment using boron-doped diamond electrode. The first electron removal leading to the formation of radical cation was identified as the rate determining step of the process. Oxidation potential values of the investigated compounds were rationalised by their solution phase ionisation energies (in conformation of the radical cations as products of the first electron removal), calculated by advanced DFT methods. Unexpectedly low oxidation potential of 2-iodobenzoic acid and its functional derivatives compared to iodobenzene, 3-iodo and 4-iodobenzoic acids was explained by decreased electron d. at iodine atom leading to planar 2-iodobenzoic acid radical cation. This is connected with reordering of its frontier MOs compared to non-planar neutral mol. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Name: 2-Methoxyethylamine).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: 2-Methoxyethylamine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Alkyl polyglucosides as hydrotropes was written by Matero, Anna;Mattsson, Asa;Svensson, Martin. And the article was included in Journal of Surfactants and Detergents in 1998.Name: 2-(2-(Hexyloxy)ethoxy)ethanol The following contents are mentioned in the article:

The hydrotropic effect of different alkyl polyglucosides (APG) was studied and compared with a model hydrotrope, toluol-4-sulfonic acid. The effect was assessed by 2 different methods: (i) as the cloud point elevation of a solution containing different nonionic surfactants upon addition of the hydrotrope and (ii) the destabilization of liquid crystalline phases in a ternary system. The effect of the hydrophobic alkyl group length was opposite in the 2 methods. APG with intermediate alkyl chain lengths (octyl and decyl) was very effective in elevating the cloud point, while APG with a short (butyl) group was the most efficient in destabilizing liquid crystalline phases in the system of water, sodium dodecyl sulfate and pentanol. Effects on phase behavior and cloud point elevation with addition of an APG are highly dependent on its structure. However, the correlation between structural effects as observed in the 2 methods requires further study. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Name: 2-(2-(Hexyloxy)ethoxy)ethanol).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: 2-(2-(Hexyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

δ-Carbolines and their ring-opened analogs: Synthesis and evaluation against fungal and bacterial opportunistic pathogens was written by Mazu, Tryphon K.;Etukala, Jagan R.;Jacob, Melissa R.;Khan, Shabana I.;Walker, Larry A.;Ablordeppey, Seth Y.. And the article was included in European Journal of Medicinal Chemistry in 2011.Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine The following contents are mentioned in the article:

Previous studies have indicated that the δ-carboline ring system derived from the natural product cryptolepine may represent a pharmacophore for anti-infective activity. The design and synthesis of a small library of substituted δ-carbolines and the evaluation of their antifungal and antibacterial activities is reported. An evaluation of the antibacterial activity of a previously reported library of ring-opened analogs was also conducted to provide an opportunity to test the hypothesis that both group of compounds may have the same biol. target. Results indicate that against a selected group of fungal pathogens, substituted δ-carbolinium analogs displayed higher potency and several fold lower cytotoxicity than cryptolepine the parent natural product. Both the δ-carbolinium compounds and their ring-opened analogs, exhibited equally high antibacterial activity against the selected pathogens and especially against the gram pos. bacteria evaluated. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of N-(4-Methoxyphenyl)pyridin-3-amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The effect of glycols and their ethers on micellar behavior of cetyltrimethylammonium tosylate was written by Padasala, Shailesh;Chavda, S.;Ray, Debes;Aswal, Vinod K.;Bahadur, Pratap. And the article was included in Journal of Molecular Liquids in 2017.Category: ethers-buliding-blocks The following contents are mentioned in the article:

The effect of glycols viz., ethylene glycol (EG), diethylene glycol (DEG) propylene glycol (PG), dipropylene glycol (DPG) and their monoalkyl ethers on the morphol. features of cetyltrimethylammonium tosylate (CTAT) micelle was examined from viscosity and small angle neutron scattering (SANS) measurements. EG and DEG, and their short chain ethers showed an initial increase in viscosity followed by a decrease while long chain PG, DPG and their ethers showed a monotonous decrease in viscosity. SANS results support the viscosity behavior. These trends are explained on the basis of hydrophobicity of the additives that determines its location in the micelle exerting an effect on micelle morphol. The critical micelle concentrations (CMCs) of CTAT determined tensiometrically for selected systems are also reported. This study helps in fine tuning of rheol. of micellar systems in the presence of gycols and their ethers often used with surfactant systems. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Category: ethers-buliding-blocks).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Thermophysical and bionotox properties of solvo-surfactants based on ethylene oxide, propylene oxide and glycerol was written by Queste, Sebastien;Michina, Youlia;Dewilde, Anny;Neueder, Roland;Kunz, Werner;Aubry, Jean-Marie. And the article was included in Green Chemistry in 2007.Application In Synthesis of 2-(2-(Hexyloxy)ethoxy)ethanol The following contents are mentioned in the article:

Thermophys. and bionotox properties of a new class of natural solvo-surfactants, glycerol 1-monoethers, were investigated in comparison with widespread but harmful glycol ethers. Vapor pressures and heats of vaporization were measured between 25 °C and 50 °C, and calculated thanks to two group contribution methods. Evaporation rates and Hansen parameters, evaluated from TGA measurements and group contributions resp., were compared as well. Bionotox properties, i.e. cytotoxicity, irritating power and biodegradability, were evaluated exptl. Glycerol 1-monoethers turned out to be less volatile than glycol derivatives, but contrary to the latter they will not be considered as VOCs. Toxicities and irritating powers are equivalent and increase with increasing alkyl chain length, i.e. with increasing amphiphilicity. Glycerol ethers are degradable at lower concentrations compared to glycol compounds, which is related to their higher interfacial activity. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Application In Synthesis of 2-(2-(Hexyloxy)ethoxy)ethanol).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application In Synthesis of 2-(2-(Hexyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Access to Unexplored 3D Chemical Space: cis-Selective Arene Hydrogenation for the Synthesis of Saturated Cyclic Boronic Acids was written by Kaithal, Akash;Wagener, Tobias;Bellotti, Peter;Daniliuc, Constantin G.;Schlichter, Lisa;Glorius, Frank. And the article was included in Angewandte Chemie, International Edition in 2022.Product Details of 1132669-90-9 The following contents are mentioned in the article:

A new class of saturated boron-incorporated cyclic mols. has been synthesized employing an arene-hydrogenation methodol. Cis-Selective hydrogenation of easily accessible, and biol. important mols. comprising benzoxaborole, benzoxaborinin, and benzoxaboripin derivatives is reported. Among the various catalysts tested, rhodium cyclic(alkyl)(amino)carbene [Rh-CAAC] (1) pre-catalyst revealed the best hydrogenation activity confirming turnover number up to 1400 with good to high diastereoselectivity. A broad range of functional groups was tolerated including sensitive substituents such as -F, -CF₃, and -silyl groups. The utility of the synthesized products was demonstrated by the recognition of diols and sugars under physiol. conditions. These motifs can have a substantial importance in medicinal chem. as they possess a three-dimensional structure, are highly stable, soluble in water, form hydrogen bonds, and interact with diols and sugars. This study involved multiple reactions and reactants, such as 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9Product Details of 1132669-90-9).

5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 1132669-90-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pre-almond supplemental forage improves colony survival and alters queen pheromone signaling in overwintering honey bee colonies was written by Carroll, Mark J.;Meikle, William G.;McFrederick, Quinn S.;Rothman, Jason A.;Brown, Nicholas;Weiss, Milagra;Ruetz, Zachary;Chang, Erica. And the article was included in Apidologie in 2018.Computed Properties of C9H12O3 The following contents are mentioned in the article:

Supplemental forage can be used to provide nutrition to bees during winter dearth. We examined the effects of supplemental forage on colony performance, colony survival, worker quality, and queen pheromone signaling in Nosema ceranae-infected overwintering colonies. Colonies were either supplemented with rapini or left unsupplemented for 1 mo before almond pollination. Unsupplemented colonies experienced higher mortality than supplemented colonies. Supplemental forage did not affect colony performance, worker mass, or hypopharyngeal gland protein content. However, supplemented queens released more of three queen QMP and QRP compounds (4-hydroxy-3-methoxyphenylethanol, Me oleate, and 1-hexadecanol) that promote queen care among workers. In addition, colonies that survived almond pollination thermoregulated their hives more than colonies that failed. Supplemental forage may prepare overwintering colonies for the stresses of early spring pollination. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Computed Properties of C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Computed Properties of C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Functionalized Triphenylene Discotic Molecules: Synthesis and Mesomorphic Characterizations was written by Srinivasa, H. T.;Hariprasad, S.. And the article was included in ChemistrySelect in 2022.HPLC of Formula: 103-16-2 The following contents are mentioned in the article:

The synthesis and characterization of two sets of triphenylene derived discotic mols. with phenol, aldehyde and acid functional groups was reported. In the first set, triphenylene moiety was tethered with benzene derivatives via an ester linkage, while in the second set via an ether linkage with increased aromatic conjugation. All the mols. have triphenylene disk at one end and with benzene, biphenyl and terphenyl cores at the other end connected via flexible methylene spacers. The chem. structures of the novel compounds were confirmed by IR, NMR spectroscopy and CHN anal. methods. Thermal and liquid crystal texture properties were determined using differential scanning calorimetry, polarized optical microscope and X-ray diffraction studies. Amongst all the novel compounds, only the terphenyl derivative displayed mesomorphism. However, their charge transfer complexes with trinitrofluorenone (TNF) an electron acceptor exhibited columnar mesophases. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2HPLC of Formula: 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Functionalized Triphenylene Discotic Molecules: Synthesis and Mesomorphic Characterizations was written by Srinivasa, H. T.;Hariprasad, S.. And the article was included in ChemistrySelect in 2022.HPLC of Formula: 103-16-2 The following contents are mentioned in the article:

The synthesis and characterization of two sets of triphenylene derived discotic mols. with phenol, aldehyde and acid functional groups was reported. In the first set, triphenylene moiety was tethered with benzene derivatives via an ester linkage, while in the second set via an ether linkage with increased aromatic conjugation. All the mols. have triphenylene disk at one end and with benzene, biphenyl and terphenyl cores at the other end connected via flexible methylene spacers. The chem. structures of the novel compounds were confirmed by IR, NMR spectroscopy and CHN anal. methods. Thermal and liquid crystal texture properties were determined using differential scanning calorimetry, polarized optical microscope and X-ray diffraction studies. Amongst all the novel compounds, only the terphenyl derivative displayed mesomorphism. However, their charge transfer complexes with trinitrofluorenone (TNF) an electron acceptor exhibited columnar mesophases. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2HPLC of Formula: 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nickel Dual Photoredox Catalysis for the Synthesis of Aryl Amines was written by Key, Ryan J.;Vannucci, Aaron K.. And the article was included in Organometallics in 2018.Electric Literature of C12H12N2O The following contents are mentioned in the article:

In this work, a new dual photoredox nickel catalysis system has been utilized for the synthesize of aryl amines. Previously, our group has shown that a nickel catalyst in conjunction with a photosensitizer and a sacrificial electron donor can cross-couple C-C bonds via photoredox-assisted reductive coupling. Here we have built upon that system to develop a redox-neutral cross-coupling system for the formation of C-N bonds. The catalytic system is composed of just a nickel cross-coupling catalyst, a Ru photocatalyst, and base and is capable of coupling amines with aryl halides in good to excellent yields. Furthermore, it was found that these reactions are functional under ambient conditions with catalyst loadings of 1 mol %. Spectroscopic studies provide support that this amination mechanism proceeds via a nitrogen-based radical intermediate. This N-radical mechanism offers direct synthetic access to di- and triaryl amines from nickel photocatalysis. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Electric Literature of C12H12N2O).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Electric Literature of C12H12N2O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem