Month: November 2022

Construction of chiral Betti base precursors containing a congested quaternary stereogenic center via chiral phosphoric acid-catalyzed arylation of isoindolinone-derived ketimines was written by Glavac, Danijel;Gredicak, Matija. And the article was included in New Journal of Chemistry in 2022.Reference of 103-16-2 The following contents are mentioned in the article:

Synthesis of enantioenriched Betti base precursors containing a congested quaternary stereocenter was described. In a chiral phosphoric acid-catalyzed reaction, a series of in-situ generated isoindolinone-derived ketimines and phenol derivatives yield products in good to excellent yields and moderate enantioselectivities. Conversion of the obtained products into chiral Betti bases with the retention of the optical purity was demonstrated. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Reference of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Reference of 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of 2-Aryloxy-1,3-dienes from Phenols and Propargyl Carbonates was written by Ishida, Naoki;Hori, Yusaku;Okumura, Shintaro;Murakami, Masahiro. And the article was included in Journal of the American Chemical Society in 2019.Formula: C13H12O2 The following contents are mentioned in the article:

A convenient method for the synthesis of 1,3-dienes from readily available compounds is reported. 2-Aryloxy-1,3-dienes are produced stereoselectively by a nickel-catalyzed reaction of propargyl carbonates with phenols. Functional group tolerance is broad to allow iodo, formyl, and boryl groups. The resulting 1,3-dienes are of much synthetic value because they can participate in a wide variety of reactions, including the Diels-Alder reaction. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Formula: C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Prediction of upper flammability limit percent of pure compounds from their molecular structures was written by Gharagheizi, Farhad. And the article was included in Journal of Hazardous Materials in 2009.Name: 2-(2-(Hexyloxy)ethoxy)ethanol The following contents are mentioned in the article:

In this study, a quant. structure-property relationship (QSPR) is presented to predict the upper flammability limit percent (UFLP) of pure compounds The obtained model is a five parameters multi-linear equation. The parameters of the model are calculated only from chem. structure. The average absolute error and squared correlation coefficient of the obtained model over all 865 pure compounds used to develop the model are 9.7%, and 0.92, resp. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Name: 2-(2-(Hexyloxy)ethoxy)ethanol).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: 2-(2-(Hexyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Preparation and catalytic activity of novel water-tolerant lanthanoid alkoxide complexes was written by Kamaura, Masahiro;Daikai, Kazuhiro;Hanamoto, Takeshi;Inanaga, Junji. And the article was included in Kidorui in 1998.HPLC of Formula: 112-59-4 The following contents are mentioned in the article:

We prepared novel water-resistant lanthanoid-lithium mixed alkoxide complexes by utilizing the high coordination number of lanthanoid ions in combination with polydentate ligands. The complexes are stable and effectively catalyze the Robinson-type reaction of 2-butanone with chalcone even in the presence of water (60 equiv to the catalyst). The terbium-lithium complex of polyethylene glycol was the most effective catalyst to the above reaction. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4HPLC of Formula: 112-59-4).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 112-59-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and biological evaluation of novel SIPI-7623 derivatives as farnesoid X receptor (FXR) antagonists was written by Nian, Si-Yun;Wang, Guo-Ping;Jiang, Zheng-Li;Xiao, Ying;Huang, Mo-Han;Zhou, Yi-Huan;Tan, Xiang-Duan. And the article was included in Molecular Diversity in 2019.Related Products of 103-16-2 The following contents are mentioned in the article:

Most of reported steroidal FXR antagonists are restricted due to low potency. We described the design and synthesis of novel nonsteroidal scaffold SIPI-7623 derivatives as FXR antagonists. The most potent compound A-11 (IC₅₀ = 7.8 ± 1.1 μM) showed better activity compared to SIPI-7623 (IC₅₀ = 40.8 ± 1.7 μM) and guggulsterone (IC₅₀ = 45.9 ± 1.1 μM). Docking of A-11 in FXR′s ligand-binding domain was also studied. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Related Products of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Power Law Expressions for Predicting Lower and Upper Flammability Limit Temperatures was written by Mathieu, Didier. And the article was included in Industrial & Engineering Chemistry Research in 2013.COA of Formula: C10H22O3 The following contents are mentioned in the article:

By analogy with recent models for flash point, the lower and upper flammability limit temperatures of organic compounds are represented as power law expressions in terms of fragment contributions. The predictive value of the resulting models compares well with recently published methods. A major advantage of the present approach is the fact it provides better insight into the relations between flammability limit temperatures and mol. structure. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4COA of Formula: C10H22O3).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.COA of Formula: C10H22O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Exploring the regioselectivity of the cyanoalkylation of 3-aza-1,5-dienes: photoinduced synthesis of 3-cyanoalkyl-4-pyrrolin-2-ones was written by He, Jia-Qin;Yang, Zhi-Xian;Zhou, Xue-Lu;Li, Yanni;Gao, Shulin;Shi, Lou;Liang, Deqiang. And the article was included in Organic Chemistry Frontiers in 2022.COA of Formula: C3H9NO The following contents are mentioned in the article:

A visible-light-induced regioselective cyanoalkylalkenylation of 1,5-dienes with oxime esters as the alkyl radical precursors was reported. Such a radical cascade proceeds with high yields and a broad substrate scope under mild conditions to provide 3-cyanoalkyl-4-pyrrolin-2-ones in one step from readily available N-vinylacrylamides. It was readily scalable to the gram scale, and could be induced by natural sunlight as a sustainable light source. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3COA of Formula: C3H9NO).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C3H9NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Novel Pd-N-heterocyclic carbene complexes: design, synthesis and application in Buchwald-Hartwig cross coupling reaction was written by Wang, Fan;Hu, Yucai;Shen, An;Cao, Yucai. And the article was included in Youji Huaxue in 2017.Reference of 562085-85-2 The following contents are mentioned in the article:

N-Heterocyclic carbene (NHC) palladium complexes with different imine ligands had been developed and applied in Buchwald-Hartwig cross coupling reaction. The structure of imine ligand would influence the catalytic activity apparently. Especially, the imine ligand with electron withdrawing group performed best. Low to 0.5 mol% catalyst loading could realize effective Buchwald-Hartwig cross coupling reaction between various aryl chlorides and amines. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Reference of 562085-85-2).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 562085-85-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of 3-Amino-5-fluoroalkylfurans by Intramolecular Cyclization was written by Placais, Clotilde;Donnard, Morgan;Panossian, Armen;Vors, Jean-Pierre;Bernier, David;Pazenok, Sergii;Leroux, Frederic R.. And the article was included in Organic Letters in 2021.Recommanded Product: 109-85-3 The following contents are mentioned in the article:

A synthesis to access rarely described 3-amino-5-fluoroalkylfurans has been developed by cyclization of easily accessible fluorovinamides. This method is rapid and simple and affords the desired furans as hydrochloride salts in quant. or nearly quant. yields. It is compatible with four different fluorinated groups (-CF₃, -CF₂CF₃, -CHF₂, and -CF₂Cl) and a wide range of substituents on the amine. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Recommanded Product: 109-85-3).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 109-85-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Photoinduced hydroxylation of arylboronic acids with molecular oxygen under photocatalyst-free conditions was written by Xu, Yu-Ting;Li, Chen-Yuan;Huang, Xiao-Bo;Gao, Wen-Xia;Zhou, Yun-Bing;Liu, Miao-Chang;Wu, Hua-Yue. And the article was included in Green Chemistry in 2019.Application of 103-16-2 The following contents are mentioned in the article:

Photoinduced hydroxylation of boronic acids RB(OH)₂ (R = octyl, 1-naphthyl, thianthren-1-yl, benzo[d][1,3]dioxol-5-yl, 9-phenyl-9H-carbazol-2-yl, etc.) with mol. oxygen under photocatalyst-free conditions is reported, providing a green entry to a variety of phenols and aliphatic alcs. ROH in a highly concise fashion. This new protocol features photocatalyst-free conditions, wide substrate scope and excellent functional group compatibility. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Application of 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem