Month: December 2022

Unveiling the nature of supramolecular crown ether-C₆₀ interactions was written by Moreira, Luis;Calbo, Joaquin;Krick Calderon, Rafael M.;Santos, Jose;Illescas, Beatriz M.;Arago, Juan;Nierengarten, Jean-Francois;Guldi, Dirk M.;Orti, Enrique;Martin, Nazario. And the article was included in Chemical Science in 2015.Category: ethers-buliding-blocks This article mentions the following:

A series of exTTF-(crown ether)₂ receptors, designed to host C₆₀, has been prepared The size of the crown ether and the nature of the heteroatoms have been systematically changed to fine tune the association constants Electrochem. measurements and transient absorption spectroscopy assisted in corroborating charge transfer in the ground state and in the excited state, leading to the formation of radical ion pairs featuring lifetimes in the range from 12 to 21 ps. To rationalize the nature of the exTTF-(crown ether)₂·C₆₀ stabilizing interactions, theor. calculations have been carried out, suggesting a synergetic interplay of donor-acceptor, π-π, n-π and CH···π interactions, which is the basis for the affinity of our novel receptors towards C₆₀. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Category: ethers-buliding-blocks).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Solvate ionic liquid boosting favorable interfaces kinetics to achieve the excellent performance of Li₄Ti₅O₁₂ anodes in Li₁₀GeP₂S₁₂ based solid-state batteries was written by Cao, Yi;Lou, Shuaifeng;Sun, Zhen;Tang, Weiping;Ma, Yulin;Zuo, Pengjian;Wang, Jiajun;Du, Chunyu;Gao, Yunzhi;Yin, Geping. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2020.Safety of 2,5,8,11-Tetraoxadodecane This article mentions the following:

Solid-state lithium batteries (SSLBs) exhibit numerous advantages including high safety, high energy d., power d., etc., and therefore it is the most promising candidate for next-generation batteries. However, constructing an intimate contact within the composite electrode and the electrode/electrolyte interface via simple mixing and cold-pressing processes is still challenging. Herein, a novel fabrication process for homogeneous composite electrodes used in SSLBs is successfully demonstrated. An in-situ liquid-phase approach employing the [Li(triglyme)]⁺[TFSI]^– (LiG3) solvent-salt complex with excellent stability to modify the sulfide-based solid-state electrolyte interfaces, is introduced into the SSLBs system, which enables SSLBs to work efficiently at lower external pressures. The quasi-solid-state prototype cells with Li₄Ti₅O₁₂ (LTO) active material deliver excellent room-temperature performance, generating a super high capacity of 160 mA h g^-1 and high capacity retention of 91.4% for 1500 cycles under 0.25 C. This work gives new insight into the interface engineering, processing and more pos. impact on the industrial production of SSLBs. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Safety of 2,5,8,11-Tetraoxadodecane).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Safety of 2,5,8,11-Tetraoxadodecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Boosting the triplet activity of heavy-atom-free difluoroboron dibenzoylmethane via sp³ oxygen-bridged electron donors was written by Huang, Wenhuan;Zhang, Xuepeng;Chen, Biao;Miao, Hui;Trindle, Carl O.;Wang, Yucai;Luo, Yi;Zhang, Guoqing. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.HPLC of Formula: 54916-28-8 This article mentions the following:

Purely organic phosphors have important applications in imaging, sensing, informatics and illumination. Methoxy-substituted difluoroboron dibenzoylmethane (BF₂dbm) complexes exhibit intense fluorescence with an almost unity quantum yield. Here, we show that by simply introducing an sp³ oxygen-bridged methoxylphenyl group as a pendant to BF₂dbm, the boron complex exhibits a triplet quantum yield of 0.16, a more than 100-fold increase compared to that of BF₂dbm. In the experiment, the researchers used many compounds, for example, 1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8HPLC of Formula: 54916-28-8).

1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.HPLC of Formula: 54916-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zinc and magnesium complexes supported by bulky multidentate amino-ether phenolate ligands: potent pre-catalysts for the immortal ring-opening polymerization of cyclic esters was written by Poirier, Valentin;Roisnel, Thierry;Carpentier, Jean-Francois;Sarazin, Yann. And the article was included in Dalton Transactions in 2011.COA of Formula: C10H21NO4 This article mentions the following:

A family of heteroleptic complexes of zinc and magnesium supported by bulky multidentate amino-ether phenolate ligands has been developed; in combination with external chain transfer agents, they constitute efficient binary catalytic systems for the immortal ring-opening polymerization of cyclic esters. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3COA of Formula: C10H21NO4).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).COA of Formula: C10H21NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Solid Electrolyte Interphase Growth on Mg Metal Anode: Case Study of Glyme-Based Electrolytes was written by Popovic, Jelena. And the article was included in Energy Technology (Weinheim, Germany) in 2021.Reference of 112-49-2 This article mentions the following:

Batteries based on Mg metal anodes promise high capacities and dendrite-free metal deposition, making them one of the most promising candidates for post-Li(Na) energy-storage technologies. Herein, for the first time, the fundamental issue of solid electrolyte interphase (SEI) growth under open circuit voltage (OCV) conditions in a Mg salt-triglyme electrolyte as observed by electrochem. impedance spectroscopy (EIS) is dealt with. The EIS suggests that SEIs are liquid/solid composites where ion transport occurs predominantly via diffusion in the encapsulated liquid Depending on the salt choice, volume percent of the liquid part of SEI is varied up to one order of magnitude. The surface limiting reaction growth mechanism proceeds through SEI densification or as a consequence of inherent mech. instabilities. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Reference of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Reference of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones was written by Wang, Zexu;Wu, Xiaofan;Li, Zhining;Huang, Zedu;Chen, Fener. And the article was included in Organic & Biomolecular Chemistry in 2019.Category: ethers-buliding-blocks This article mentions the following:

We report here the stereoselective bioreduction of α-nitro ketones catalyzed by ketoreductases (KREDs) with publicly known sequences. YGL039w and RasADH/SyADH were able to reduce 23 class I substrates (1-aryl-2-nitro-1-ethanone (1)) and ten class II substrates (1-aryloxy-3-nitro-2-propanone (4)) to furnish both enantiomers of the corresponding β-nitro alcs., with good-to-excellent conversions (up to >99%) and enantioselectivities (up to >99% ee) being achieved in most cases. To the best of our knowledge, KRED-mediated reduction of class II α-nitro ketones (1-aryloxy-3-nitro-2-propanone (4)) is unprecedented. Select β-nitro alcs., including the synthetic intermediates of bioactive mols. (R)-tembamide, (S)-tembamide, (S)-moprolol, (S)-toliprolol and (S)-propanolol, were stereoselectively synthesized in preparative scale with 42% to 90% isolated yields, showcasing the practical potential of our developed system in organic synthesis. Finally, the advantage of using KREDs with known sequence was demonstrated by whole-cell catalysis, in which β-nitro alc. (R)-2k, the key synthetic intermediate of hypoglycemic natural product (R)-tembamide, was produced in a space-time yield of 178 g L^-1 d^-1 as well as 95% ee by employing the whole cells of a recombinant E. coli strain coexpressing RasADH and glucose dehydrogenase as the biocatalyst. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Category: ethers-buliding-blocks).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Metabolism of N-acylated and O-alkylated drugs by intestinal microflora during anaerobic incubation in vitro was written by Smith, G. E.;Griffiths, L. A.. And the article was included in Xenobiotica in 1974.Quality Control of 3-(2,4-Dimethoxyphenyl)acrylic acid This article mentions the following:

Phenacetin [62-44-2] and derivatives of acetanilide were N-deacylated by rat cecal microflora, the deacylation of the latter being dependent on the nature and position of the substituents. Thus, p-alkylated or o-, m-, or p-hydroxylated derivatives were deacylated, whereas a p-aromatic or halide substituent or an aromatic acyl grouping prevented deacylation. A few O-alkylated compounds with a simple benzenoid structure were dealkylated by cecal microflora, but none of the N-alkylated drugs were dealkylated. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Quality Control of 3-(2,4-Dimethoxyphenyl)acrylic acid).

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Quality Control of 3-(2,4-Dimethoxyphenyl)acrylic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and Biological Activity of N-Aroyl (Aryloxyacetyl)-N’-ferrocenyl Thiourea Derivatives was written by Zhang, Qiong;Zhao, Bihong;Song, Yangyang;Hua, Chengwen;Gou, Xiaofeng;Chen, Bang;Zhao, Junlong. And the article was included in Heteroatom Chemistry in 2015.Related Products of 1877-75-4 This article mentions the following:

In this study, the synthesis of aminoferrocene was improved and a series of novel ferrocene-containing thiourea compounds were designed and synthesized as potential plant growth regulators. All the new compounds were characterized by IR, ¹H NMR, and x-ray crystallog. Furthermore, the cytokinin and auxin activities of 5c and 5a–i were investigated. Notably, compounds 5e, 5g, and 5j in a concentration of 50 μg/mL exhibited significant cytokinin activity, and compounds 5b and 5h in a concentration of 50 μg/mL exhibited higher auxin activity than indoleacetic acid. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Related Products of 1877-75-4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Related Products of 1877-75-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and evaluation of new BODIPY-benzofuroquinoline conjugates for sensitive and selective DNA detection was written by Du, Gang;Huang, Su-Mei;Zhai, Peng;Chen, Shuo-Bin;Hua, Wen-Zhao;Tan, Jia-Heng;Ou, Tian-Miao;Huang, Shi-Liang;Li, Ding;Gu, Lian-Quan;Huang, Zhi-Shu. And the article was included in Dyes and Pigments in 2014.Application In Synthesis of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

The sensitive and selective detection of nucleic acids is important for basic research and many applied fields. Herein, a series of new BODIPY-benzofuroquinoline conjugates were designed, synthesized and evaluated as DNA intercalating dyes. All compounds were characterized by using ¹H, ¹³C NMR, IR, UV-Vis and fluorescence spectroscopy, and DNA binding properties of these conjugates to calf thymus DNA were studied by using fluorescence titration, UV titration, isothermal titration calorimetry and CD anal. Significant enhancement of the fluorescent quantum yield was observed for all the conjugates in the presence of calf thymus DNA, and one compound showed excellent sensitivity and selectivity offering its potential application as a DNA specific fluorescent probe. Our results showed that these conjugates could intercalate into calf thymus DNA with high binding affinities. The properties of these dyes as fluorescent probes for living cells imaging were also investigated. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Application In Synthesis of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Application In Synthesis of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Palladium-catalyzed direct ortho-alkynylation of arylalkylacid derivatives at γ and δ positions via an N,O-bidentate directing group was written by Li, Guobao;Liu, Pei;Zhang, Jingyu;Shi, Da-Qing;Zhao, Yingsheng. And the article was included in Organic Chemistry Frontiers in 2017.Safety of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

Palladium-catalyzed ortho-alkynylation of arylalkylacid derivatives at remote γ and δ positions with the assistance of an N,O-bidentate directing group of glycine dimethylamide (GDMA) is reported for the first time. A wide variety of phenylacetic acid and 3-phenylpropionic acid derivatives is tolerated in this protocol, which provides a general means to synthesize substituted alkynylarylalkyl acid derivatives, e.g., I. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Safety of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Safety of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem