Month: December 2022

Xing, Chuanwang published the artcilePerylenetetracarboxylic diimide covalently bonded with mesoporous g-C₃N₄ to construct direct Z-scheme heterojunctions for efficient photocatalytic oxidative coupling of amines, Application In Synthesis of 6850-57-3, the publication is Applied Catalysis, B: Environmental (2021), 120534, database is CAplus.

Photocatalytic oxidative coupling of amines is a promising method for imine synthesis. In this paper, a robust covalently-bonded direct Z-scheme heterostructure (PDI/mpgCN) for photocatalytic oxidative coupling of amine was reported for the first time. Perylenetetracarboxylic diimide (PDI) mols. were covalently connected to the surface of mesoporous carbon nitride (mpgCN) via an in-situ condensation strategy. Compared with the poor conversion efficiency upon pristine g-C₃N₄, PDI/mpgCN heterostructure exhibits a remarkable enhancement on amine oxidation rate (AOR), with the optimal AOR reaches to as high as 20.63 mmol g^-1 h^-1 upon 20 % PDI/mpgCN. As far as we know, it is the highest AOR achieved so far for amine photooxidation coupling with heterojunction materials. Transient absorption studies proved the formation of Z-scheme junction, and efficient interfacial charge transfer. Our study not only makes an insight into the heterojunction design with chem. bond precision, but highlights the great prospects of Z-scheme photocatalyst in photo-chem. synthesis.

Applied Catalysis, B: Environmental published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C10H9IO4, Application In Synthesis of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ishiyama, Haruaki published the artcileEnantioselective total synthesis of eudistomidins G, H, and I, Formula: C25H23NO4, the publication is Tetrahedron (2012), 68(31), 6186-6192, database is CAplus.

Asym. first total synthesis of eudistomidins G, H, and I, tetrahydro-β-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus, has been accomplished with the Bischler-Napieralski reaction and the Noyori catalytic asym. hydrogen-transfer reaction. The absolute configurations of eudistomidins G, H, and I were confirmed from comparison of the ¹H and ¹³C NMR, and CD spectral data of synthetic and natural eudistomidins G, H, and I, resp.

Tetrahedron published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C25H23NO4, Formula: C25H23NO4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Kreutzer, Adam G. published the artcileStabilization, Assembly, and Toxicity of Trimers Derived from Aβ, Category: ethers-buliding-blocks, the publication is Journal of the American Chemical Society (2017), 139(2), 966-975, database is CAplus and MEDLINE.

Oligomers of the β-amyloid peptide Aβ have emerged as important contributors to neurodegeneration in Alzheimer’s disease. Mounting evidence suggests that Aβ trimers and higher-order oligomers derived from trimers have special significance in the early stages of Alzheimer’s disease. Elucidating the structures of these trimers and higher-order oligomers is paramount for understanding their role in neurodegeneration. This paper describes the design, synthesis, X-ray crystallog. structures, and biophys. and biol. properties of two stabilized trimers derived from the central and C-terminal regions of Aβ. These triangular trimers are stabilized through three disulfide crosslinks between the monomer subunits. The X-ray crystallog. structures reveal that the stabilized trimers assemble hierarchically to form hexamers, dodecamers, and annular pore-like structures. Solution-phase biophys. studies reveal that the stabilized trimers assemble in solution to form oligomers that recapitulate some of the higher-order assemblies observed crystallog. The stabilized trimers share many of the biol. characteristics of oligomers of full-length Aβ, including toxicity toward a neuronally derived human cell line, activation of caspase-3 mediated apoptosis, and reactivity with the oligomer-specific antibody A11. These studies support the biol. significance of the triangular trimer assembly of Aβ β-hairpins and may offer a deeper understanding of the mol. basis of Alzheimer’s disease.

Journal of the American Chemical Society published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C25H23NO4, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Shimizu, Satoko published the artcileEffect of type of aromatic nucleus in lignin on the rate of the β-O-4 bond cleavage during alkaline pulping process, Formula: C16H18O4, the publication is Journal of Wood Science (2015), 61(5), 529-536, database is CAplus.

Several C₆-C₃ and C₆-C₂-type dimeric non-phenolic β-O-4 lignin model compounds, whose aromatic nuclei consisting of the carbon skeleton and β-O-4 linkage are named the A- and B-rings, resp., were treated under alk. pulping conditions to examine whether or not the substitution of methoxyl group on the B-ring or of guaiacyl for syringyl A-ring accelerates the β-O-4 cleavage as a further study of our previous reports. It was suggested that either first or second substitution of methoxyl group on the B-ring accelerates the β-O-4 cleavage in both C₆-C₃ and C₆-C₂ compounds although the former compounds are more sensitive to the substitution than the latter, suggesting that the lack of the γ-hydroxymethyl group makes model compound insensitive to the substitution. It was confirmed that the substitution of guaiacyl for syringyl A-ring accelerates the β-O-4 cleavage in both C₆-C₃ and C₆-C₂ compounds with the degrees similar to each other regardless of the type of the B-ring. It was clarified that the leaving ability of the leaving B-ring phenoxides in the β-O-4 cleavage does not correlate well with the p^Ka values of the conjugate acids of the phenoxides, which is not in accordance with the common property of a nucleophilic substitution reaction.

Journal of Wood Science published new progress about 183303-74-4. 183303-74-4 belongs to ethers-buliding-blocks, auxiliary class Benzene,Alcohol,Ether, name is 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol, and the molecular formula is C3H5BN2O2, Formula: C16H18O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Kang, Qiaoxiang published the artcileHollow multi-shelled In₂S₃ hierarchical nanotubes for enhanced photocatalytic oxidative coupling of benzylamine, Quality Control of 6850-57-3, the publication is Journal of Solid State Chemistry (2022), 123087, database is CAplus.

The unique structural features of the hollow and hierarchical structures give light to the developing categories of photocatalysts as a promising way to deal with the challenges involved in the process of heterogeneous photocatalysis. Herein, hollow multi-shelled In₂S₃ hierarchical nanotubes have been fabricated using NH₂-MIL-68 (In) as template and TAA. The results demonstrated that hollow multi-shelled In₂S₃ hierarchical nanotubes has been used as an efficient photocatalyst for the coupling of benzylamines under visible light irradiation and aerobic or anaerobic conditions, which burst out of the shackles of the reported reaction conditions. And the conversion and selectivity reached 74% and 99%, resp. The hierarchical structure with nanosheet on the surface of hollow multi-shelled nanotube have effectively promote the mass transfer and photogenerated carrier separation, increasing the number of reactive points. Then, it also has proved that the hole (h⁺), the nitrogen-centered radical cations as well as the carbon-centered radicals were most important in the reaction. This work provides a novel concept for further design of unique structural photocatalyst for boosting the catalytic activity.

Journal of Solid State Chemistry published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Quality Control of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sahin, Neslihan published the artcileFirst used of Alkylbenzimidazole-Cobalt(II) complexes as a catalyst for the N-Alkylation of amines with alcohols under solvent-free medium, Related Products of ethers-buliding-blocks, the publication is Journal of Organometallic Chemistry (2020), 121285, database is CAplus.

Alkylbenzimidazole-cobalt(II) I [R = allyl, 2-methylallyl, 2-vinyloxyethyl]-catalyzed direct N-alkylation reactions of amines with alcs. derivatives was investigated under solvent-free medium. For this purpose, a series of cobalt(II) complexes I was synthesized and novel complexes fully characterized by elemental anal., FT-IR, ¹H-NMR and ¹³C-NMR spectroscopies. Also, the structure of the complex I [R = allyl] was confirmed by X-ray crystallog. Generally, the N-alkylating reaction is usually performed in toluene with various metal complexes including cobalt. In this catalytic study of complexes I, was carried out without solvent and alc. acted both as solvent and reactant. Conversion and selectivity of amine products according to imine products for alkylation reactions were seen high yield in medium solvent-free relative to in toluene.

Journal of Organometallic Chemistry published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Vafai, Yassaman published the artcilePrenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status, Category: ethers-buliding-blocks, the publication is Journal of Maternal-Fetal & Neonatal Medicine, database is CAplus and MEDLINE.

The association between obesity (body mass index (BMI) ≥ 30 kg/m2) and pattern of medication use during pregnancy in the United States is not well-studied. Higher pre-pregnancy BMI may be associated with increases or decreases in medication use across pregnancy as symptoms (e.g. reflux) or comorbidities (e.g. gestational diabetes) requiring treatment that may be associated with higher BMI could also change with advancing gestation. To determine whether prenatal medication use, by the number and types of medications, varies by pre-pregnancy obesity status. In a secondary data anal. of a racially/ethnically diverse prospective cohort of pregnant women with low risk for fetal abnormalities enrolled in the first trimester of pregnancy and followed to delivery (singleton, 12 United States clin. sites), free text medication data were obtained at enrollment and up to five follow-up visits and abstracted from medical records at delivery. In 436 women with obesity and 1750 women without obesity (pre-pregnancy BMI, 19-29.9 kg/m2), more than 70% of pregnant women (77% of women with and 73% of women without obesity) reported taking at least one medication during pregnancy, resp. (adjusted risk ratio (aRR)=1.10, 95% confidence interval (CI)=1.01, 1.20), with 81% reporting two and 69% reporting three or more. A total of 17 classes of medications were identified. Among medication classes consumed by at least 5% of all women, the only class that differed between women with and without obesity was hormones and synthetic substitutes (including steroids, progesterone, diabetes, and thyroid medications) in which women with obesity took more medications (11 vs. 5%, aRR = 1.9, 95% CI = 1.38, 2.61) compared to women without obesity. Within this class, a higher percentage of women with obesity took diabetes medications (2.3 vs. 0.7%) and progesterone (3.4 vs. 1.3%) than their non-obese counterparts. Similar percentages of women with and without obesity reported consuming medications in the remaining medication classes including central nervous system agents (50 and 46%), gastrointestinal drugs (43 and 40%), anti-infective agents (23 and 21%), antihistamines (20 and 17%), autonomic drugs (10 and 9%), and respiratory tract agents (7 and 6%), resp. (p > 0.05 for all adjusted comparisons). There were no differences in medication use by obesity status across gestation. Since the study exclusion criteria limited the non-obese group to women without thyroid disease, in a sensitivity anal. we excluded all women who reported thyroid medication intake and still a higher proportion of women with obesity took the hormones and synthetic substitutes class compared to women without obesity. Our findings suggest that pre-pregnancy obesity in otherwise healthy women is associated with a higher use of only selected medications (such as diabetes medications and progesterone) during pregnancy, while the intake of other more common medication types such as analgesics, antibiotics, and antacids does not vary by pre-pregnancy obesity status. As medication safety information for prenatal consumption is insufficient for many medications, these findings highlight the need for a more in-depth examination of factors associated with prenatal medication use.

Journal of Maternal-Fetal & Neonatal Medicine published new progress about 637-58-1. 637-58-1 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is 4-(3-(4-Butoxyphenoxy)propyl)morpholine hydrochloride, and the molecular formula is C19H14N2, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Bagheri, Mehdi published the artcileMolecular modeling of the standard state heat of formation, SDS of cas: 1589-47-5, the publication is Energy Conversion and Management (2013), 587-596, database is CAplus.

The standard heat of formation is a basic thermophys. property required in determining enthalpies of reaction and in thermodn. stability analyses. Further, the enthalpies of formation are important in investigating bond energies, resonance energies and the nature of chem. bonds. Therefore, the development of accurate structure-based estimation methods for large varieties of chem. species is greatly beneficial in enhancing capability in process and product development. In this work, quant. structure-property relationship (QSPR) models were developed for a structurally diverse DIPPR dataset of standard heats of formation comprising 1765 pure compounds involving 82 chem. classes. We have employed both linear and nonlinear QSPR modeling techniques. The linear approach involves the use of constricted binary particle swarm optimization (BPSO) for feature selection and multiple-linear regression. In the nonlinear approach, the optimum network architecture and its associated inputs are identified using a wrapper-based feature selection algorithm combining differential evolution and artificial neural networks. Model predictions for the root-mean-square error of the BPSO and nonlinear approaches were 138 and 97 kJ/mol, resp.

Energy Conversion and Management published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, SDS of cas: 1589-47-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Chen, Zhiyong published the artcileDiastereoselective synthesis of the acyl side-chain and amino acid (2S,3R)-3-hydroxy-3-methylproline fragments of polyoxypeptin A, Application In Synthesis of 99438-28-5, the publication is Synlett (2005), 2781-2785, database is CAplus.

Synthesis of the acyl side-chain and amino acid (2S,3R)-3-hydroxy-3-methylproline units of the potent depsipeptide polyoxypeptin A, is described. Key intermediates were secured via diastereoselective addition involving a homoenolate ion and allylation of an aminoketone, resp.

Synlett published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Application In Synthesis of 99438-28-5.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Zhen published the artcileAn S-scheme α-Fe₂O₃/Cu₂O photocatalyst for an enhanced primary amine oxidative coupling reaction under visible light, Safety of (2-Methoxyphenyl)methanamine, the publication is Dalton Transactions (2022), 51(27), 10578-10586, database is CAplus and MEDLINE.

Here, an S-scheme α-Fe₂O₃/Cu₂O heterojunction photocatalyst was designed and fabricated for the primary amines oxidative coupling reaction to give aryl imines. On account of that, the S-scheme structure effectively separated the photogenerated electron-hole pairs and enhanced the photoredox ability of the photocatalytic system. The α-Fe₂O₃/Cu₂O composite could also enhance the reactivity to a large extent. This work will provide new insight into the design of photocatalysts with a more reasonable structure and higher performance.

Dalton Transactions published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Safety of (2-Methoxyphenyl)methanamine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem