Month: December 2022

Menk, Florian published the artcileReactivity Studies of Alkoxy-Substituted [2.2]Paracyclophane-1,9-dienes and Specific Coordination of the Monomer Repeating Unit during ROMP, Formula: C15H24O2, the publication is Macromolecules (Washington, DC, United States) (2015), 48(20), 7435-7445, database is CAplus.

The polymerization of alkoxy-substituted [2.2]paracyclophane-1,9-dienes via ring-opening metathesis polymerization (ROMP) to obtain soluble poly(p-phenylenevinylene)s is a versatile method due to its living nature which enables the possibility of block copolymerization and end group modification. However, detailed studies on the reactivity behavior and the polymerization process of alkoxy-substituted [2.2]paracyclophane-1,9-dienes have not been reported so far. Herein we present a detailed study on the varying tendencies of the four isomers of dimethoxy-(2-ethylhexyloxy)-[2.2]paracyclophane-1,9-diene to undergo ROMP. Therefore, we carried out polymerization combining all individual isomers with five different metathesis catalysts and collected initiation and propagation kinetics for various combinations. Furthermore, we revealed a specific coordination of the monomer repeating unit to the catalyst during the polymerization process and succeeded to polymerize not only the pseudogeminal isomers but also one of the pseudo-ortho isomers.

Macromolecules (Washington, DC, United States) published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, Formula: C15H24O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Ledovskikh, V. M. published the artcilePolarographic study of the reaction of thiourea with copper(II) sulfate, COA of Formula: C2H8Cl2N4S2, the publication is Zhurnal Obshchei Khimii (1976), 46(1), 11-15, database is CAplus.

Results are given on the reaction of thiourea [62-56-6] and some of its derivatives with CuSO4 [7758-98-7] in H2SO4 solutions by using the polarog. method. The anomalous behavior can be explained by the presence of highly surface-active complexes of Cu(I) with thiourea. The thiourea and its derivatives is oxidized by the Cu(II) ion to form the appropriate formamidine disulfide, together with complexes of the original substance with Cu(I). Quant. determination of the products of the reaction are possible by polarog. The presence in the H2SO4 electrolyte of Cu compounds of the disulfide class is a necessary condition for the brightening action of dimethylolthiourea [3084-25-1] and its dialkyl esters.

Zhurnal Obshchei Khimii published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, COA of Formula: C2H8Cl2N4S2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Merey, Hanan A. published the artcileSimultaneous determination of pramocaine HCl and hydrocortisone acetate in pharmaceutical dosage form, Category: ethers-buliding-blocks, the publication is Journal of Liquid Chromatography & Related Technologies (2013), 36(19), 2774-2784, database is CAplus.

Two sensitive and selective methods were developed and validated for simultaneous determination of pramocaine HCl and hydrocortisone acetate in pharmaceutical dosage form. The first method is a spectrodensitometric method where pramocaine HCl and hydrocortisone acetate were separated using toluene:methanol:chloroform: 10% NH₃ [(5:3:6:0.1, by volume) as the developing system followed by densitometric measurement at 290 nm] and 250 nm for pramocaine HCl and hydrocortisone acetate, resp. The second method is a high performance liquid chromatog. method for separation and determination of both drugs using reversed phase C₁₈ column and mobile phase consisting of distilled water:acetonitrile:triethylamine (530:470:0.1, by volume); pH was adjusted to 3 by o-phosphoric acid. The proposed methods were successfully applied for the anal. of pramocaine HCl and hydrocortisone acetate in laboratory prepared mixtures and in pharmaceutical dosage form and the results obtained were assessed by applying the standard addition technique. Statistical comparison between the results obtained by applying the proposed methods and official method for the cited drugs was done and no significant difference was found at p = 0.05.

Journal of Liquid Chromatography & Related Technologies published new progress about 637-58-1. 637-58-1 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is 4-(3-(4-Butoxyphenoxy)propyl)morpholine hydrochloride, and the molecular formula is C17H28ClNO3, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Marstokk, K.-M. published the artcileStructural and conformational properties of methoxyacetamide as studied by microwave spectroscopy and ab initio computations, Recommanded Product: 2-Methoxyacetamide, the publication is Acta Chemica Scandinavica (1996), 50(9), 845-847, database is CAplus.

Ab initio (6-311+G^** level) structure, rotational constants, dipole moments and energy differences of the three rotomers of methoxyacetamide found to be min. on the potential energy surface.

Acta Chemica Scandinavica published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Recommanded Product: 2-Methoxyacetamide.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Ruyu published the artcileSynthesis and properties of poly(p-phenylene vinylene) derivatives with hyperbranched structure and containing a nitro substituent, COA of Formula: C15H24O2, the publication is Monatshefte fuer Chemie (2014), 145(1), 85-90, database is CAplus and MEDLINE.

In order to improve efficiency, processability, and stability, two groups of novel poly(p-phenylene vinylene) (PPV) derivatives (P₁-P₃ and P₄-P₆) with hyperbranched structure and containing a nitro substituent were synthesized via a Gilch reaction in different monomer ratios. The properties of the polymers were investigated by using UV-Vis absorption, fluorescence spectroscopy, cyclic voltammetry, and thermogravimetric anal. The result shows that the band gaps of the PPV derivatives with a nitro substituent were decreased and the polymers had higher mol. weights (10⁶), excellent solubility in common organic solvents, good film-forming ability, and better thermal stability. The polymers can be used as an efficient acceptor material in polymeric solar cells.

Monatshefte fuer Chemie published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, COA of Formula: C15H24O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Shimizu, Ken-ichi published the artcileSilica-Supported Silver Nanoparticles with Surface Oxygen Species as a Reusable Catalyst for Alkylation of Arenes, COA of Formula: C10H14O, the publication is ChemCatChem (2010), 2(1), 84-91, database is CAplus.

A series of silica-supported silver catalysts with various Ag loading (3-30 wt %) and different treatment (oxidation and subsequent reduction by H₂) were prepared, and their local structures were characterized by extended x-ray absorption fine structure (EXAFS) anal. In oxidized catalysts, silver were mainly present as small nanoparticles with surface oxygen atoms, and the number of surface oxygen atoms decreased with increased silver loading. The H₂ reduction of these samples resulted in a removal of the surface oxygen atoms. The structure-activity relationship was studied for the alkylation of anisole with benzyl alc. and styrene. Ag^I oxide, Ag^I ion, bulk silver metal, and silica-supported silver nanoparticles were non-active species. In contrast, silica-supported silver nanoparticles with the surface oxygen atoms acted as an effective heterogeneous catalyst for the alkylation of arenes with alcs. and styrenes. Kinetic studies in alkylation of anisole with alcs. showed that the cleavage of the α-C-H bond of alc. was the rate-limiting step. It is proposed that the surface oxygen adjacent to the silver surface atoms plays an important role in the dissociation of the α-C-H bond.

ChemCatChem published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C9H9NO6S, COA of Formula: C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Subagyono, Rr dirgarini j. n. published the artcilePyrolysis of fast growing wood Macaranga gigantea: Product characterisation and kinetic study, Formula: C9H10O4, the publication is Fuel (2022), 123182, database is CAplus.

Fast-growing wood Macaranga gigantea has been pyrolyzed and its pyrolysis products have been characterized and their formation kinetics studied. Pyrolysis of M. gigantea wood was carried out by varying the temperature and time of pyrolysis to determine the effect of these two parameters on product yields and product characteristics. In general, an increase in pyrolysis temperature and time increased the yield of liquid and gas products, the concentration of cellulose, hemicellulose and lignin-derived compounds, but decreased the biochar yield. The organic phase liquid pyrolysis products mainly contained phenolic compounds and their derivatives, eugenols, furans, aldehydes and ketones. Fourier-transform IR spectroscopy and pyrolysis-gas chromatog.-mass spectrometry analyses of biochar showed that thermal decomposition of M. gigantea required temperatures higher than 300°C to optimize thermal decomposition and carbonization of lignin, cellulose and hemicellulose. The concentration of phenols and benzenediols in biochar decreased with an increase in pyrolysis temperature M. gigantea pyrolysis kinetics studies showed that wood pyrolysis occurred through four main stages with activation energy (Eα) values, based on calculations by the Friedman and Kissinger-Akahira-Sunose methods, of 28.1-99.0 kJ/mol and 35.6-104.9 kJ/mol, resp. The spectra produced by thermogravimetric analyzer coupled with a Fourier-transform IR spectroscopy showed that H₂O and CO₂ were produced during pyrolysis and the volatile compounds produced were predominantly phenolic compounds, in accord with characterization results of the liquid products by gas chromatog.-mass spectrometry and NMR spectroscopy.

Fuel published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C8H11NO, Formula: C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Palav, Amey published the artcileNCBSI/KI: A Reagent System for Iodination of Aromatics through In Situ Generation of I-Cl, Application In Synthesis of 93-04-9, the publication is Journal of Organic Chemistry (2021), 86(17), 12467-12474, database is CAplus and MEDLINE.

In-situ iodine monochloride (I-Cl) generation followed by iodination of aromatics using NCBSI/KI system was developed. The NCBSI reagent required no activation due to longer bond length, lower bond dissociation energy, and higher absolute charge d. on nitrogen. The system was adequate for mono- and diiodination of a wide range of moderate to highly activated arenes with good yield and purity. Moreover, the precursor N-(benzenesulfonyl)benzenesulfonamide was recovered and transformed to NCBSI and made the protocol eco-friendly and cost-effective.

Journal of Organic Chemistry published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Application In Synthesis of 93-04-9.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Jayaraman, Arumugam published the artcilePractical and scalable synthesis of borylated heterocycles using bench-stable precursors of metal-free lewis pair catalysts, Formula: C11H17BO3S, the publication is Organic Process Research & Development (2018), 22(11), 1489-1499, database is CAplus.

Five-membered heterocycles undergo borylation and hydroboration with HBpin boronate in a green scalable process under catalysis with o-phenylene borate-amine frustrated Lewis pairs, yielding substituted boronic esters. A practical and scalable metal-free catalytic method for the borylation and borylative dearomatization (hydroboration) of pyrroles and indoles has been developed. This synthetic method uses inexpensive and conveniently synthesizable bench-stable precatalysts of the form 1-NHR₂-2-BF₃-C₆H₄, com. and synthetically accessible heteroarenes as substrates, and pinacolborane as the borylation reagent. The preparation of several borylated heterocycles on 2 and 50 g scales was achieved under solvent-free conditions without the use of Schlenk techniques or a glovebox. A kilogram-scale borylation of one of the heteroarene substrates was also achieved using this cost-effective green methodol. to exemplify the fact that our methodol. can be conveniently implemented in fine chem. industries.

Organic Process Research & Development published new progress about 596819-12-4. 596819-12-4 belongs to ethers-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Ether,Boronate Esters,Boronic acid and ester, name is 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C11H17BO3S, Formula: C11H17BO3S.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Alibakhshi, A. published the artcilePrediction of flash points of pure organic compounds: Evaluation of the DIPPR database, Name: 2-Methoxypropan-1-ol, the publication is Process Safety and Environmental Protection (2017), 127-133, database is CAplus.

The flash point is one of the most important flammability properties of compounds for the design of inherently safe processes. Many models have been developed to predict the flash point using the DIPPR database. However, for only 740 of the 1628 organic compounds available in the DIPPR database, the data for both flash point and normal b.p. were exptl. determined For the other compounds, at least one of these properties was predicted and therefore is not appropriate for model development. The present study introduces a model to predict the flash points of pure organic compounds using their mol. structures and normal b.ps. The new model exploits the equality of the relative errors observed for the normal b.p. and flash point values predicted using the Joback method. Consequently, the relative error of the predicted normal b.ps. can be used as a scaling factor to modify the predicted flash points. The ability of the model to evaluate the accuracy of a database was investigated. The ratio of the relative error of the predicted flash point to the relative error of the predicted normal b.p. obtained using the Joback method was proposed as a measure to evaluate the accuracy of flash point data.

Process Safety and Environmental Protection published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Name: 2-Methoxypropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem