Category: 23783-42-8

Pipertzis, Achilleas published the artcileIonic Conductivity in Polyfluorene-Based Diblock Copolymers Comprising Nanodomains of a Polymerized Ionic Liquid and a Solid Polymer Electrolyte Doped with LiTFSI, COA of Formula: C9H20O5, the main research area is ionic conductivity polyfluorene diblock copolymer polymer electrolyte doped LiTFSI.

Diblock copolymer electrolytes based on a π-conjugated polyfluorene (PF) backbone were synthesized comprising nanodomains of a polymerized ionic liquid (PIL) and of a solid polymer electrolyte (SPE). The former consists of a single-ion conductor based on an imidazolium alkyl chain with a [Br]- counteranion grafted on the PF backbone. The latter consists of short ethylene oxide (EO) chains, grafted on the PF backbone and further doped with LiTFSI. The two nanophases support ionic conductivity, whereas the rigid PF backbone provides the required mech. stability. In the absence of LiTFSI, ionic conductivity in the PIL nanophase is low and exhibits an Arrhenius temperature dependence. LiTFSI substitution enhances ionic conductivity by about 3 orders of magnitude and further changes to a Vogel-Fulcher-Tammann temperature dependence. However, at ambient temperature, ionic conductivity is lower than in the corresponding PEO/LiTFSI electrolytes. X-ray studies and thermal anal. revealed that the conjugated backbone imparts liquid-crystalline order that can be fine-tuned through the EO side group length. Ionic conductivity measurements performed as a function of pressure identified local jumps of [Li]+ and [Br]- ions in the resp. SPE/PIL nanophases as responsible for the ionic conductivity Between the two ions, it is [Li]+ that has the major contribution to the ionic conductivity The current results provide designing rules for new copolymers that comprise two different ionic nanodomains (PIL and SPE) and a conjugated backbone that can further support electronic conduction.

Macromolecules (Washington, DC, United States) published new progress about Diffusion. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, COA of Formula: C9H20O5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Berac, Christian M. published the artcileEvaluation of charge-regulated supramolecular copolymerization to tune the time scale for oxidative disassembly of β-sheet comonomers, Computed Properties of 23783-42-8, the main research area is peptide solid phase synthesis self Click chem assembly nanorod; nanorod peptide polymer beta sheet charge TEM CD; supramol structure peptide dendrimer nanorod oxidation disassembly kinetics; kinetic control; multicomponent supramolecular polymers; reactive oxygen species responsive materials; redox regulation; supramolecular chemistry.

A multistimuli-responsive supramol. copolymerization is reported. The copolymerization is driven by hydrogen bond encoded β-sheet-based charge co-assembly into 1D nanorods in water, using glutamic acid or lysine residues in either of the peptide comonomers. The incorporation of methionine as hydrophobic amino acid supports β-sheet formation, but oxidation of the thioether side-chain to a sulfoxide functional group destabilizes the β-sheet ordered domains and induces disassembly of the supramol. polymers. Using H2O2 as reactive oxygen species, the time scale and kinetics of the oxidative disassembly are probed. Compared to the charge neutral homopolymers, it is found that the oxidative disassembly of the charged ampholytic copolymers is up to two times faster and is operative at neutral pH. The strategy is therefore an important addition to the growing field of amphiphilic polythioether containing (macro)mol. building blocks, particularly in view of tuning their oxidation induced disassembly which tends to be notoriously slow and requires high concentrations of reactive oxygen species or acidic reaction media.

Macromolecular Rapid Communications published new progress about Azidation. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Computed Properties of 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Byrne, Stephen A. published the artcileLate-stage modification of peptides and proteins at cysteine with diaryliodonium salts, Formula: C9H20O5, the main research area is cysteine diaryliodonium salt peptide protein modification.

The modification of peptides and proteins has emerged as a powerful means to efficiently prepare high value bioconjugates for a range of applications in chem. biol. and for the development of next-generation therapeutics. Herein, we report a novel method for the chemoselective late-stage modification of peptides and proteins at cysteine in aqueous buffer with suitably functionalised diaryliodonium salts, furnishing stable thioether-linked synthetic conjugates. The power of this new platform is showcased through the late-stage modification of the affibody zEGFR and the histone protein H2A.

Chemical Science published new progress about Arylation. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Formula: C9H20O5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lin, En published the artcileA Class of Rigid-Flexible Coupling Crystalline Crosslinked Polymers as Vapomechanical Actuators, Related Products of ethers-buliding-blocks, the main research area is rigid flexible coupling crystalline crosslinked polyazomethine vapomech actuator; Covalent Organic Frameworks; Crosslinked Polymer; Crystalline; Smart Materials; Vapor Responsive.

Fabricating mech. responsive actuators that can efficiently convert external stimuli into mech. work is of great significance for real-world applications. Herein, we rationally design a class of rigid-flexible coupling crystalline crosslinked polymers (CCPs) to fabricate vapomechanically responsive actuators. Interfacial condensation reactions of flexible macromers with rigid monomers afford a series of freestanding CCP membranes. Notably, it is the first example where crosslinked polymers show high crystallinity and porosity. Moreover, the CCP membranes exhibit good mech. properties and interesting vapor-triggered actuation performance, which is reversible and repeatable. We find that the unusual polymer structures, high vapor sorption, and anisotropic membranes contribute to the directional deformation performance of the CCP actuators. The synthesis approach in this work provides new insights into the design and fabrication of smart materials for advanced applications.

Angewandte Chemie, International Edition published new progress about Actuators. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Related Products of ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pang, Long published the artcileDesign of crown ether based micelles and their anti-tumor properties by perturbing potassium ion homeostasis, Name: 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is crown ether micelle potassium ion homeostasis antitumor.

Chemotherapy is one of the most used method for cancer therapy, however, brings huge pain to patients as the drugs commonly causes side effects. Inducing tumor cells apoptosis by perturbing ion homeostasis is a novel approach to replace chemotherapy in recent years. Crown ether has been widely used since it was discovered in the last century and has shown its potential in biol. applications. The aim of this paper is to design a series of novel nanometer micelles with crown ether on their surface. Crown ether was connected to a commonly used amphiphilic polymeric carrier, PEG-PCL, through ester bond (CPMs). Micelles about 120 nm in diameter were formed in aqueous solution The micelles could capture potassium ions prominently in both aqueous solution and tumor cells. In vitro and in vivo experiments showed that the CPMs had certain anti-tumor activity, indicating that the CPMs had anti-tumor potential.

Materials & Design published new progress about Adsorption. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Name: 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Na published the artcileBacteriochlorin aggregates as dopant-free hole-transporting materials for perovskite solar cells, Product Details of C9H20O5, the main research area is bacteriochlorin aggregate hole transport perovskite solar cell electrochem property.

Organic-inorganic hybrid perovskite solar cells (PSCs) have attracted great interests not only of academic field but also of industrial world toward practical applications in the last decade due to their extremely low production cost and excellent photo-phys. properties. Hole-transporting layer (HTL) as an integral component of PSC plays an important role in elevating its performance. In this work, five bacteriochlorophyll-a derivatives characterized by different C17-propionate residue were prepared and their J-type aggregates were investigated as HTLs of PSCs. It was confirmed that the nature of the introduced C17-propionate side chains have negligible effects on the electrochem. properties of main dye unit, such as the electronic absorption spectra and energy levels. However, the different lipophilicity, hydrophilicity, or hydrophobicity of chain characters affect the solubility of each dye component, resulting in diverse surface morphologies of their aggregate films as revealed by AFM observations. Furthermore, the five solid films prepared by spin-coating method showed discrepant charge extraction and transport abilities as HTLs, which were supported by both photo luminescence spectra and electrochem. impedance spectroscopy measurement results and were concluded to be the fundamental reason of the different PSC performance.

Organic Electronics published new progress about Aggregates. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Product Details of C9H20O5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yiu, Asteria published the artcileFacile Synthesis of Novel Thermo-Responsive Polyvalerolactones with Tunable LCSTs, COA of Formula: C9H20O5, the main research area is thermoresponsive polyvalerolactone biodegradable tunable lower critical solution temperature; oligoethylene glycol functionalized polyvalerolactone thermal tunable.

Thermoresponsive polymers have emerged as promising candidates for biomedical applications. Seven novel oligoethylene glycol (OEG) functionalized polyvalerolactones P1-P7 are synthesized from poly(α-allyl-δ-valerolactone) via thiol-ene addition post-polymerization modification. All seven polymers exhibit thermoresponsive behavior with lower critical solution temperatures (LCSTs) ranging from 13.8 to 92.2°C. Polymers P5-P7 are synthesized via thiol-ene addition reaction using two thiol mixtures at three different ratios. LCSTs of P5-P7 fall in between those of P1 and P2, and exhibit a linear relationship, indicating a tunable thermoresponsive system. This newly developed system offers great control for a desired thermoresponsive biocompatible, biodegradable polymeric system with desired LCSTs.

Macromolecular Chemistry and Physics published new progress about Aggregates. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, COA of Formula: C9H20O5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bartolec, Boris published the artcileEmergence of Compartments Formed from Unconventional Surfactants in Dynamic Combinatorial Libraries, Computed Properties of 23783-42-8, the main research area is combinatorial library self assembly membrane.

Assembly processes can drive the selection of self-assembling mols. in dynamic combinatorial libraries, yielding self-synthesizing materials. We now show how such selection in a dynamic combinatorial library made from an amphiphilic building block which, by itself, assembles into micelles, can yield membranous aggregates ranging from vesicles to sponge phases. These aggregates are made from a mixture of unconventional surfactant mols., showing the power of dynamic combinatorial selection approaches for the discovery of new, not readily predictable, self-assembly motifs.

Langmuir published new progress about Aggregates. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Computed Properties of 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bach, Nicolai N. published the artcileActive Mechanical Threading by a Molecular Motor, Safety of 2,5,8,11-Tetraoxatridecan-13-ol, the main research area is active mech threading mol motor; Hemithioindigo; Indigoids; Molecular Machines; Molecular Motors; Photochemistry.

Mol. motors transform external energy input into directional motions and offer exquisite precision for nano-scale manipulations. To make full use of mol. motor capacities, their directional motions need to be transmitted and used for powering downstream mol. events. Here we present a macrocyclic mol. motor structure able to perform repetitive mol. threading of a flexible tetraethylene glycol chain through the macrocycle. This mech. threading event is actively powered by the motor and leads to a direct translation of the unidirectional motor rotation into unidirectional translation motion (chain vs. ring). The mechanism of the active mech. threading is elucidated and the actual threading step is identified as a combined helix inversion and threading event. The established mol. machine function resembles the crucial step of macroscopic weaving or sewing processes and therefore offers a first entry point to a “”mol. knitting”” counterpart.

Angewandte Chemie, International Edition published new progress about Alkylation. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Safety of 2,5,8,11-Tetraoxatridecan-13-ol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Delehedde, Caroline published the artcileNovel Sterically Crowded and Conformationally Constrained α-Aminophosphonates with a Near-Neutral pKa as Highly Accurate 31P NMR pH Probes. Application to Subtle pH Gradients Determination in Dictyostelium discoideum Cells, Computed Properties of 23783-42-8, the main research area is Dictyostelium discoideum cell aminophosphonate neutral pKa NMR pH probe; 31P NMR; Dictyostelium discoideum cells; X-ray crystallography; pH probes; phophorus pyramidalization angle; trans-sarcolemmal pH gradients; α-aminophosphonates.

In order to discover new 31P NMR markers for probing subtle pH changes (<0.2 pH unit) in biol. environments, fifteen new conformationally constrained or sterically hindered α-aminophosphonates derived from diethyl(2-methylpyrrolidin-2-yl)phosphonate were synthesized and tested for their pH reporting and cytotoxic properties in vitro. All compounds showed near-neutral pKas (ranging 6.28-6.97), chem. shifts not overlapping those of phosphorus metabolites, and spectroscopic sensitivities (i.e., chem. shifts variation Δδab between the acidic and basic forms) ranging from 9.2-10.7 ppm, being fourfold larger than conventional endogenous markers such as inorganic phosphate. X-ray crystallog. studies combined with predictive empirical relationships and ab initio calculations addressed the inductive and stereochem. effects of substituents linked to the protonated amine function. Satisfactory correlations were established between pKas and both the 2D structure and pyramidalization at phosphorus, showing that steric crowding around the phosphorus is crucial for modulating Δδab. Finally, the hit 31P NMR pH probe 1b bearing an unsubstituted 1,3,2-dioxaphosphorinane ring, which is moderately lipophilic, nontoxic on A549 and NHLF cells, and showing pKa = 6.45 with Δδab = 10.64 ppm, allowed the first clear-cut evidence of trans-sarcolemmal pH gradients in normoxic Dictyostelium discoideum cells with an accuracy of <0.05 pH units. Molecules published new progress about Biomarkers. 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Computed Properties of 23783-42-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem