Category: 33100-27-5

Bhuyar, Prakash; Rahim, Mohd hasbi ab.; Maniam, Gaanty pragas; Govindan, Natanamurugaraj published their research in Journal of Microbiology, Biotechnology and Food Sciences in 2021. The article was titled 《Isolation and characterization of bioactive compounds in medicinal plant Centella asiatica and study the effects on fungal activities》.Computed Properties of C10H20O5 The article contains the following contents:

Medicinal plants are sources of important therapeutic aids for alleviating human ailments. The present research investigation was carried out to study anti-fungal activity of C. asiatica were tested against C. albicans, Aspergillus niger, and Penicillium sp. using two methods, disk diffusion method and broth dilution method. C. asiatica crude methanol extract was found to be the most effective against fungal activity. Compared to disk diffusion, broth dilution was a more appropriate method to quant. determine the anti-Candida activity of plant extract, whereby the MIC values of the crude extracts was determined The result from disk diffusion assay demonstrates that plant extracts have an inhibitory effect. However, the broth dilution method result reveal that C. asiatica crude methanol extract has lower MIC values, meaning it has more prove that C. asiatica has an anti-fungal effect. Bioactive anal. results reveled that bioactive compounds present in the leaf, stems, roots, and the whole plant extract from Centella asiatica are the major chem. constituents are n-Hexadecanoic acid (99%), cis-Vaccenic acid (91%), 5-Hydroxymethylfurfural (88%), Tetradecanoic acid (86%). Further study is required to find out the specific phytochem. which is responsible for its medicinal value. In the part of experimental materials, we found many familiar compounds, such as 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Computed Properties of C10H20O5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Computed Properties of C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Antibacterial and antifungal study on novel Ag(I)-15C5 complexes》 was published in European Journal of Biomedical and Pharmaceutical Sciences in 2020. These research results belong to Chitlangia, Seema; Ranjan, Rajeev. Reference of 1,4,7,10,13-Pentaoxacyclopentadecane The article mentions the following:

Crown ether is a general name given to macrocyclic polyethers containing ethylene bridges separating electroneg. oxygen atoms. They typically contain central electron rich hydrophilic cavity with diameter varying from 1.2-6.0 Å. Crown ethers have been used for the various studies pertaining to extraction equilibrium constant, stability constant and for determination of some of the alkali and alk. earth elements and other elements from p, d and f-block elements. Crown ethers have a significant coordination power towards silver ion. The present paper describes synthesis, characterization and antimicrobial study of novel Ag(I) complexes synthesized by 15-crown-5 ether. The organic salts used for complexation were salts of nitrophenols. Products were isolated from silver salts of all the three nitrophenols, 2-nitrophenol(ONPH), 2,4-dinitrophenol(DNPH) and 2,4,6-trinitrophenol(TNPH), having general formula of [Ag.L](Pic-), where L = 15C5 and Pic- = Picrate anion. Elemental anal., molar conductivity, UV-Vis, IR, and 1H-NMR spectral anal. were performed for establishment of the structure of synthesized complexes. Antibacterial activities of the synthesized complexes were determined by using Kirby Bauer disk diffusion method. Antibacterial and antifungal activity of the prepared complexes were determined and recorded by zone inhibition method. The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Reference of 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Reference of 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Destructive-quantum-interference suppression in crown ether single molecule junction》 was published in European Physical Journal B: Condensed Matter and Complex Systems in 2020. These research results belong to Mijbil, Zainelabideen Y.; Essa, Haider O.. Quality Control of 1,4,7,10,13-Pentaoxacyclopentadecane The article mentions the following:

The electronic transmission coefficient of X-crown ether-Y (X = 3Y ;Y = 4, 5, and 6) have been investigated using d. functional theory and Green’s function approximation incorporated with the Huckel method. The results illustrate unexpected role of the oxygen atoms to highly enhance charge transport in the crown ether mols. by moving the destructive quantum interferences (QI) close to the Fermi level. Such slight shifting creates a beneficial peak-valley pattern in the transmission spectra that facilitates the ON/OFF variation. Moreover, the length of the crown ether rings offers an insignificant impact on electronic transmission. Hence, we believe that these findings would deepen our understanding of QI patterns and exploit crown ether mols. more practically and efficiently in mol. devices. The results came from multiple reactions, including the reaction of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Quality Control of 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Quality Control of 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Eichstaedt, Natalie; van der Zwan, Kasper P.; Mayr, Lina; Siegel, Renee; Senker, Juergen; Breu, Josef published an article in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences. The title of the article was 《Crystal structure of phenanthrenide salts stabilized by 15-crown-5 and 18-crown-6》.Application In Synthesis of 1,4,7,10,13-Pentaoxacyclopentadecane The author mentioned the following in the article:

Potassium 15-crown-5 phenanthrenide and potassium 18-crown-6 phenanthrenide were synthesized and characterized by powder X-ray diffraction and 39K solid state NMR spectroscopy. While the radical carbanion is very reactive in solution, the crystals are stable and storable under inert atm. For 15-crown-5, a sandwich-like complex of potassium is formed with two mols. of crown ether per potassium resulting in a coordination number of 10. For the larger 18-crown-6 ligand, a 1:1 complex is obtained and a coordination number of 6 for the potassium cation. In neither crystal structure solvent mols. are incorporated. The 15-crown-5 compound crystallizes faster and is less soluble in THF as compared to the 18-crown-6 compound Both compounds form solid phenanthrenide that is easy to handle and can be applied for reduction reactions. In the experimental materials used by the author, we found 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Application In Synthesis of 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Application In Synthesis of 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Ahsin, Atazaz; Jadoon, Tabish; Ayub, Khurshid published an article in Physica E: Low-Dimensional Systems & Nanostructures (Amsterdam, Netherlands). The title of the article was 《M@[12-crown-4] and M@[15-crown-5] where (M=Li, Na, and K); the very first examples of non-conventional one alkali metal-containing alkalides with remarkable static and dynamic NLO response》.Synthetic Route of C10H20O5 The author mentioned the following in the article:

Excess electron compounds, such as alkalides, were shown to be promising nonlinear optical (NLO) materials with higher static and frequency-dependent nonlinearities. The intriguing alkalides are obtained after doping the alkali metals with crown ethers M@[12-crown-4] and M@[15-crown-5] (where M=Li, Na, and K). The studied complexes are thermodynamically stable and their interactions energies range from -66.51 to -3.51 kcal mol-1. The geometric, electronic, and nonlinear optical properties are validated through d. functional theory at the CAM-B3LYP/6-31+G(d,p) level of theory. The significant (neg.) NBO charge present on alkali metals reveals their alkalide characteristics. Furthermore, reduced HOMO-LUMO gaps for the designed complexes show their excellent electronic and conductive properties. Being excess electron candidate the significant static first hyperpolarizability value increased up to 1.2 x 107 au where the βvec response recorded up to 1.1 x 107 au. The total hyperpolarizability nicely correlates with hyperpolarizability (βtl) which suggests their excellent NLO properties. Besides, the dynamic hyperpolarizability response for electro-optical pockel’s effect β(-2ω;ω,0) increases up to 3.5 x 107 au at dispersion frequency of 1064 nm. The dynamic hyperpolarizability responses for SHG are much pronounced at the larger dispersion frequency. The dynamic second hyperpolarizability response for the dc-Kerr effect increases up to 6.4 x 109 au. The frequency-dependent NLO response of M@[12-crown-4] alkalides is slightly larger than those of M@[12-crown-4]. Moreover, the hyper Rayleigh scattering hyperpolarizability (βHRS) value is calculated up to 3.4 x 106 au. The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Synthetic Route of C10H20O5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Synthetic Route of C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem