Category: 529-28-2

《Unconventional Reactivity with DABCO-Bis(sulfur dioxide): C-H Bond Sulfenylation of Imidazopyridines》 was published in European Journal of Organic Chemistry in 2020. These research results belong to Le Bescont, Julie; Breton-Patient, Chloe; Piguel, Sandrine. Application In Synthesis of 1-Iodo-2-methoxybenzene The article mentions the following:

This work highlights the unexpected and unprecedented outcome of the reactivity with DABCO-bis(sulfur dioxide). The use of this reagent led to the exclusive introduction of a sulfur atom on the C-3 position of imidazopyridines instead of a sulfone group. The reaction methodol. turned out to be robust, scalable and suitable for various imidazopyridines and aryl iodides both bearing substituents with different electronic and steric properties (38 examples). Beyond the fact that this synthetic method complements the previously reported protocols for sulfenylation reactions, this work is meant to underline the unconventional role of DABCO-bis(sulfur dioxide). Thus, e.g., 2-phenylimidazo[1,2-a]pyridine + PhI + DABSO → I (68%) in presence of CuI/phenanthroline and tBuOK in DMF at 140°. A polemic in response to the work of D. Yang et al. (2018), who reported the preparation of sulfones under similar conditions. The results came from multiple reactions, including the reaction of 1-Iodo-2-methoxybenzene(cas: 529-28-2Application In Synthesis of 1-Iodo-2-methoxybenzene)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Application In Synthesis of 1-Iodo-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Chemical Research in Chinese Universities included an article by Wang, Junzhong; Li, Hengyu; Zhang, Dongdong; Bai, Jie. Product Details of 529-28-2. The article was titled 《Amorphous Cu0 on Carbon Nanofiber as Recyclable Heterogeneous Catalyst for N-Arylation Reactions》. The information in the text is summarized as follows:

A novel heterogeneous catalyst, amorphous Cu0 on the carbon nanofibers was developed and characterized by means of several characterization techniques. The prepared Cu0 was investigated as a heterogeneous catalyst for N-arylation reaction. The results show that is an excellent catalyst with recyclability, high consistency and catalytic activity. After the catalyst was used for 5 cycles in the N-arylation reaction, amorphous Cu0 reunited into crystalline copper nanoparticles with different particle sizes and its good heterogeneity in the catalytic system was confirmed after the catalyst recovery.1-Iodo-2-methoxybenzene(cas: 529-28-2Product Details of 529-28-2) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Product Details of 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Kan; Yao, Yanxiu; Sun, Wenjin; Wen, Rui; Wang, Yanyan; Sun, Huaming; Zhang, Weiqiang; Zhang, Guofang; Gao, Ziwei published an article in 2021. The article was titled 《Triazine-wingtips accelerated NHC-Pd catalysed carbonylative Sonogashira cross-coupling reaction》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Formula: C7H7IO The information in the text is summarized as follows:

By using a ppm-level precatalyst T-NHC-Pd, the highly efficient coupling of aryl iodide, alkyne and carbon monoxide furnished a variety of ynone compounds T-NHC-Pd, which deprotonated 4-methyl-phenylacetylene under mild conditions, converted into alkynyl-coordinated catalytic active species PdCl(T-NHC)(Py)(alkynyl). In the putative Pd/Pd catalytic cycle, both triazine-wingtips and NHCs were key players for establishing the carbonylative cross-couplings with high TON and TOF. After reading the article, we found that the author used 1-Iodo-2-methoxybenzene(cas: 529-28-2Formula: C7H7IO)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Formula: C7H7IO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Gao, Qianwen; Liu, Ze-Shui; Hua, Yu; Li, Lisha; Cheng, Hong-Gang; Cong, Hengjiang; Zhou, Qianghui. Application of 529-28-2. The article was titled 《A palladium/norbornene cooperative catalysis to access N-containing bridged scaffolds》. The information in the text is summarized as follows:

A palladium/norbornene cooperative catalysis promoted annulation involving an ortho-C-H amination and intramol. Heck cascade between aryl iodides ArI (Ar = 2-methylphenyl, 3-fluoro-2-methylphenyl, naphthalen-1-yl, etc.) and functionalized amination reagents I (R = Me, Et, benzyl, cyclopropylmethyl, 2-methylpropyl) is reported, thereby providing a highly convergent access to the unique N-containing bridged scaffolds: hexahydro-2,6-methano-1-benzazocine II (R1 = Me, F, C6H5, etc.; R2 = H, Me, F; R3 = H, F, C(O)2CH3, etc.; R1R2 = CH=CH-CH=CH). The salient features of the reaction include its broad substrate scope (with respect to aryl iodides), its high step economy, and good chemoselectivity. Preliminary studies underscore the future promise of rendering this Catellani-type annulation enantioselective.1-Iodo-2-methoxybenzene(cas: 529-28-2Application of 529-28-2) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Application of 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《DMAP and PivOH-promoted amination/allenization reaction》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Zhang, Bo-Sheng; Li, Yuke; Gou, Xue-Ya; Zhang, Zhe; An, Yang; Wang, Xin-Gang; Liang, Yong-Min. Quality Control of 1-Iodo-2-methoxybenzene The article mentions the following:

This report described the first DMAP and PivOH-promoted ortho-C-H amination and ipso-allenization reaction of iodobenzenes realized by Pd/norbornene cooperative catalysis. Based on control experiments and DFT calculations, the authors speculated that the three ligands have different functions and mechanism paths in the reaction. In the experiment, the researchers used many compounds, for example, 1-Iodo-2-methoxybenzene(cas: 529-28-2Quality Control of 1-Iodo-2-methoxybenzene)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Quality Control of 1-Iodo-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem