60656-87-3 Archives - Page 2 of 9 - Ethers-buliding-blocks

Chen, Yuye’s team published research in Organic Letters in 2019 | CAS: 60656-87-3

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Related Products of 60656-87-3

In 2019,Organic Letters included an article by Chen, Yuye; Hu, Jingping; Guo, Lian-Dong; Tian, Peilin; Xu, Tianyue; Xu, Jing. Related Products of 60656-87-3. The article was titled 《Synthesis of the Core Structure of Daphnimacropodines》. The information in the text is summarized as follows:

Daphniphyllum alkaloids daphnimacropodines A-C possess a highly congested ring system and share a common tetracyclic ring skeleton. To access the challenging chem. structure of daphnimacropodines, a divergent synthetic approach toward their total synthesis is described. A stereoselective synthesis of the core structure I of daphnimacropodines has been achieved from a simple diketone building block. Our approach features an intramol. carbamate aza-Michael addition and a hydropyrrole synthesis via a Au-catalyzed alkyne hydration followed by an aldol condensation, whereas all the other attempts failed.2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Related Products of 60656-87-3) was used in this study.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhao, Jing’s team published research in Organic Letters in 2021 | CAS: 60656-87-3

Zhao, Jing; Chen, Jiuxi; Xu, Qing; Li, Huan published their research in Organic Letters in 2021. The article was titled 《Synthesis of Benzoxaboroles by ortho-Oxalkylation of Arylboronic Acids with Aldehydes/Ketones in the Presence of Bronsted Acids》.Application In Synthesis of 2-(Benzyloxy)acetaldehyde The article contains the following contents:

Herein the authors describe a simple and efficient synthesis of benzoxaboroles from arylboronic acids and aldehydes or ketones in the presence of a Bronsted acid. This method greatly simplifies the starting materials and reduces the number of reaction steps. The reaction can also be accomplished with acetals and ketals. The reaction has a wide substrate scope and high practicability. After reading the article, we found that the author used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Application In Synthesis of 2-(Benzyloxy)acetaldehyde)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Heberle, Martin’s team published research in ChemCatChem in 2022 | CAS: 60656-87-3

Heberle, Martin; Legendre, Sarah; Wannenmacher, Nick; Weber, Manuel; Frey, Wolfgang; Peters, Rene published an article in 2022. The article was titled 《Bispalladacycle Catalyzed Nucleophilic Enantioselective Allylation of Aldehydes by Allylstannanes》, and you may find the article in ChemCatChem.Product Details of 60656-87-3 The information in the text is summarized as follows:

The first palladium catalysts capable of controlling asym. nucleophilic allylations of aldehydes with allyltributyltin was reported. TONs up to 620 were achieved, which is significantly higher than for any other reported catalyst. The method also tolerated electronically and sterically unfavorable substrates. It was showed that transmetallation occurred, favoring an η1-allyl coordination mode with the bispalladacycles. In contrast, for the corresponding monopalladacycle an unproductive η3 coordination was dominant. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Product Details of 60656-87-3)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhong, Tao’s team published research in Chemical Science in 2021 | CAS: 60656-87-3

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Recommanded Product: 2-(Benzyloxy)acetaldehyde

Recommanded Product: 2-(Benzyloxy)acetaldehydeIn 2021 ,《Photoredox-catalyzed aminofluorosulfonylation of unactivated olefins》 was published in Chemical Science. The article was written by Zhong, Tao; Yi, Ji-Tao; Chen, Zhi-Da; Zhuang, Quan-Can; Li, Yong-Zhao; Lu, Gui; Weng, Jiang. The article contains the following contents:

The first three-component aminofluorosulfonylation of unactivated olefins, e.g., cyclohex-2-en-1-yl N-(4-chlorophenyl)carbamate by merging photoredox-catalyzed proton-coupled electron transfer (PCET) activation with radical relay processes has been described. Various aliphatic sulfonyl fluorides featuring a privileged 5-membered heterocyclic core compounds, e.g., I have been efficiently afforded under mild conditions with good functional group tolerance. The synthetic potential of the sulfonyl fluoride products has been examined by diverse transformations including SuFEx reactions and transition metal-catalyzed cross-coupling reactions. Mechanistic studies demonstrate that amidyl radicals, alkyl radicals and sulfonyl radicals are involved in this difunctionalization transformation. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Recommanded Product: 2-(Benzyloxy)acetaldehyde)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xue, Sijing’s team published research in Organic Letters in 2021 | CAS: 60656-87-3

Name: 2-(Benzyloxy)acetaldehydeIn 2021 ,《Asymmetric Synthesis of Homoallylic Alcohols Featuring Vicinal Tetrasubstituted Carbon Centers via Dual Pd/Photoredox Catalysis》 was published in Organic Letters. The article was written by Xue, Sijing; Limburg, Bart; Ghorai, Debasish; Benet-Buchholz, Jordi; Kleij, Arjan W.. The article contains the following contents:

Dual palladium/photoredox-catalysis provides an effective method for the decarboxylative asym. synthesis of vicinal α,β-tri/tetra- or α,β-tetrasubstituted homoallylic alcs. using Hantzsch-type esters as radical precursors. This mild methodol. capitalizes on vinyl cyclic carbonates as accessible reagents providing the target mols. in appreciable to good yields, high branch selectivity, and enantiomeric ratios of up to 94:6, making it a rare example of using prochiral electrophiles for the creation of vicinal congested carbon centers. After reading the article, we found that the author used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Name: 2-(Benzyloxy)acetaldehyde)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Kato, Shota’s team published research in Chemical Science in 2021 | CAS: 60656-87-3

Kato, Shota; Mizukami, Daichi; Sugai, Tomoya; Tsuda, Masashi; Fuwa, Haruhiko published their research in Chemical Science in 2021. The article was titled 《Total synthesis and complete configurational assignment of amphirionin-2》.Reference of 2-(Benzyloxy)acetaldehyde The article contains the following contents:

Herein the first total synthesis of amphirionin-2 and determination of its absolute configuration was disclosed. This synthesis featured an extensive use of cobalt-catalyzed Mukaiyama-type cyclization of γ-hydroxy olefins for stereoselective formation of all the THF rings found in the natural product and a late-stage Stille-type coupling for convergent assembly of the entire carbon backbone. Four candidate diastereomers of amphirionin-2 were synthesized in a unified, convergent manner and their spectroscopic/chromatog. properties were compared with those of the authentic material. The present study culminated in the reassignment of the C5/C7 relative configuration, assignment of the C12/C18 relative configuration, and determination of the absolute configuration of amphirionin-2. In the experimental materials used by the author, we found 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Reference of 2-(Benzyloxy)acetaldehyde)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Han, Xing-Wang’s team published research in CCS Chemistry in 2021 | CAS: 60656-87-3

Han, Xing-Wang; Zhang, Tao; Yao, Wei-Wei; Chen, Hao; Ye, Mengchun published their research in CCS Chemistry in 2021. The article was titled 《Nickel- and Bronsted acid-catalyzed redox-neutral coupling of 1,3-dienes and aldehydes for synthesis of dienols》.Category: ethers-buliding-blocks The article contains the following contents:

Dienols are important structural motifs in organic mols., but most of the traditional synthetic methods required multistep prefunctionalization of substrates, leading to stoichiometric waste and low atom economy. Herein, a redox-neutral coupling of simple 1,3-dienes and aldehydes via nickel and Bronsted acid dual catalysis, providing a highly atom-economical and byproduct-free route to various dienols with up to 94% yield and up to 50:1 EE/EZ ratio is reported. The use of 2-isopropoxyphenol as a Bronsted acid co-catalyst was critical to the reactivity and selectivity. The experimental process involved the reaction of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Category: ethers-buliding-blocks)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Shuangqing’s team published research in ACS Catalysis in 2021 | CAS: 60656-87-3

Li, Shuangqing; Wang, Shuangshuang; Li, Juan; Qi, Yue; Wang, Chao; Zong, Lili; Tan, Choon-Hong published an article in 2021. The article was titled 《Monocationic Cinchoninium Catalyzed Asymmetric Oxohydroxylation of Enoates》, and you may find the article in ACS Catalysis.Electric Literature of C9H10O2 The information in the text is summarized as follows:

In this paper, asym. oxohydroxylation of α-alkyl enoates RCH=C(R1)C(O)OR2 (R = Me, cyclohexyl, furan-2-yl, etc.; R1 = Me, prop-2-en-1-yl, prop-2-yn-1-yl, Bn, etc.; RR1 = -(CH2)3-, -(CH2)4-; R2 = Et, Bn, 2-(4-methoxyphenyl)-2-oxoethyl) with potassium permanganate catalyzed by monocationic quaternary ammonium salts I (R3 = H, Bn, (2-bromo-3,5-di-tert-butylphenyl)methyl, [3,5-bis(3,5-di-tert-butylphenyl)phenyl]methyl, etc.; R4 = Br, F, CF3; R5 = F, CF3, [3,5-bis(trifluoromethyl)phenyl]methyl) derived from cinchona alkaloid is reported. A series of α-hydroxy-β-keto esters RC(O)C(R1)(OH)C(O)OR2 were obtained in up to 96% yield and 98% ee under user-friendly conditions. Synthetic application of oxohydroxylation was demonstrated in the synthesis of key chiral building blocks for thapsigargin and camptothecin synthesis. Control experiments indicated that, compared with tetrabutylammonium, monocationic chiral cinchoninium has a dramatic rate acceleration effect on catalytic permanganate oxidation After reading the article, we found that the author used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Electric Literature of C9H10O2)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Zhenhao’s team published research in ACS Catalysis in 2022 | CAS: 60656-87-3

Zhang, Zhenhao; Sabat, Nazarii; Frison, Gilles; Marinetti, Angela; Guinchard, Xavier published an article in 2022. The article was titled 《Enantioselective Au(I)-Catalyzed Multicomponent Annulations via Tethered Counterion-Directed Catalysis》, and you may find the article in ACS Catalysis.Category: ethers-buliding-blocks The information in the text is summarized as follows:

Gold(I) complexes of a chiral phosphoric acid-functionalized phosphine of the CPA-Phos series enable the enantioselective multicomponent reactions between aldehydes, hydroxylamines, and cyclic yne-enones, leading to 3,4-dihydro-1H-furo[3,4-d][1,2]oxazines. This represents a rare example of a highly enantioselective multicomponent reaction in gold(I) catalysis. The reactions proceed at a low catalyst loading and provide high yields, total diastereoselectivity, and enantiomeric excesses up to 99%. Silver-free conditions was applied. The method had a very broad scope as it applies to both aliphatic and aromatic aldehydes and hydroxylamines, to a variety of cyclic yne-enones, and to yne-enone-derived oximes. DFT calculations complement this study to enlighten reactivity issues and mechanistic pathways. The experimental part of the paper was very detailed, including the reaction process of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Category: ethers-buliding-blocks)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jung, Woo-Ok’s team published research in Organic Letters in 2022 | CAS: 60656-87-3

Jung, Woo-Ok; Yoo, Minjin; Migliozzi, Madyson M.; Zbieg, Jason R.; Stivala, Craig E.; Krische, Michael J. published an article in 2022. The article was titled 《Regio- and Enantioselective Iridium-Catalyzed Amination of Alkyl-Substituted Allylic Acetates with Secondary Amines》, and you may find the article in Organic Letters.Computed Properties of C9H10O2 The information in the text is summarized as follows:

Robust air-stable cyclometalated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were observed despite the formation of more highly substituted C-N bonds. The experimental part of the paper was very detailed, including the reaction process of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Computed Properties of C9H10O2)

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem